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The map label for this gene is 92114888

Identifier: 92114888

GI number: 92114888

Start: 3101158

End: 3102384

Strand: Direct

Name: 92114888

Synonym: Csal_2770

Alternate gene names: NA

Gene position: 3101158-3102384 (Clockwise)

Preceding gene: 92114879

Following gene: 92114889

Centisome position: 83.89

GC content: 66.42

Gene sequence:

>1227_bases
ATGCAGTCCCAGAGCCAATCCCCCGCCGTCGAGATGAGCGAGCTGTTCCCTTACGCACAAGGGCCCGCACTGCGCACCAG
TCAGGCCCACGACAAGGCGCTGGAGATCATCTGGGAAAACGCCGACAGCGCGCGCTTCAGCTACCGCTGGCTGCGCGACC
ACTGCGCCTGCCCCGAGTGCCGTCATCCCATGACGCGCGAGCGTCTTTACATGCCGCTCGAGGACGAAAACTTCCTGAAC
GCCCGGCCCGAAGCCAGCGTCGAGGACGGCGTGCTGGTGCTGCGCTGGGCCGACGGTCACGAGTCGCGCTTCGACGCCGG
CTGGCTGCACCAGCGCCGTCCCGAATCGCGCATCGATGACGGCGTTCCCCGTGCCGAAGCCTGGCGCGAAGGCTTCACCC
CGGCACATGTGCCGCATGCCGAGATGATGGGCGGCCACGAGGGCCGGCGCGAGTGGCTGACCGCCCTGTTGCGCGACGGC
CTGGTCCTGCTCGACGACGGTCCGCGCGAGCTCGAGGAGGTCGTGCGCATCGCCGAACTGTTCGGGCCGATGCGGGCCAC
CAACTTCGGCGCACGTTTCGACGTCCAGTCCAAGCCGAACCCCAACAATGCCGCTTACACGGCCATCGGCCTCGAGCTGC
ACACCGACCTTCCCAACTGGCGCCATCCGCCGGACATCCAGCTGCTGTATTGCCTGGAGAATGAAGCCGAAGGCGGCGAA
TCGCTGTTCGCCGATGGCTTCGCCGTGGCCGAGGCGCTGCGTCATGAAGCGCCGGAGCTCTTCCTCCGTCTGCGCGATAC
GCCCATCGATTTCCGTTTCCAGGACGAAGACAGCGACATCGCCGTGCGCGCGCCGGTCATCGAGGTCGATGACACCGGCC
GCATTCGTGAAGTCCGCTTCAACAACTGGATTCGCGACACCCTGCGCCTGCCGCCGGAAGAAGCCGACGCCTGGTACGAG
GCTTACCTGGTCTTCTGGCAGCGCCTGCGCGAGCCGCGCTTCCGCGTCGACTTCGCGCTCGAACCCGGCCAGATGGTCGC
CTTCGACAACCGTCGTGTACTGCACGGGCGTGGCGCCTTCGACCCCAATACCGGTCGTCGCCACCTCCAGGGCACCTATC
TGGACATCGATCACCTCGAATCGCATCTACGCGTGCTGGCGCGCCACGCCACTTCCGCCGCGCCCGACACCCCGACAACA
TCCACCAATGAAACGGGAGTTTCCTAA

Upstream 100 bases:

>100_bases
CAAATCTTGGCCTCAGGTCCGAGATTCATCGTTTGTCTAATGTCGCCATGAGGCGACATGCTAGTGGCCGATTCGCACGA
CCCAATATCAGGAGGCCAGC

Downstream 100 bases:

>100_bases
TGTCTCATTCGCTTCGTCCCTTGCTCGTCGGACTGCCGCTCGCCGCGGGTATCGGCATGGCCATGCCGGCCCAGGCCGCA
GAGCAGATACGCTTCGGCGT

Product: gamma-butyrobetaine,2-oxoglutarate dioxygenase

Products: NA

Alternate protein names: Gamma-butyrobetaine hydroxylase; Gamma-BBH; Gamma-butyrobetaine,2-oxoglutarate dioxygenase [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MQSQSQSPAVEMSELFPYAQGPALRTSQAHDKALEIIWENADSARFSYRWLRDHCACPECRHPMTRERLYMPLEDENFLN
ARPEASVEDGVLVLRWADGHESRFDAGWLHQRRPESRIDDGVPRAEAWREGFTPAHVPHAEMMGGHEGRREWLTALLRDG
LVLLDDGPRELEEVVRIAELFGPMRATNFGARFDVQSKPNPNNAAYTAIGLELHTDLPNWRHPPDIQLLYCLENEAEGGE
SLFADGFAVAEALRHEAPELFLRLRDTPIDFRFQDEDSDIAVRAPVIEVDDTGRIREVRFNNWIRDTLRLPPEEADAWYE
AYLVFWQRLREPRFRVDFALEPGQMVAFDNRRVLHGRGAFDPNTGRRHLQGTYLDIDHLESHLRVLARHATSAAPDTPTT
STNETGVS

Sequences:

>Translated_408_residues
MQSQSQSPAVEMSELFPYAQGPALRTSQAHDKALEIIWENADSARFSYRWLRDHCACPECRHPMTRERLYMPLEDENFLN
ARPEASVEDGVLVLRWADGHESRFDAGWLHQRRPESRIDDGVPRAEAWREGFTPAHVPHAEMMGGHEGRREWLTALLRDG
LVLLDDGPRELEEVVRIAELFGPMRATNFGARFDVQSKPNPNNAAYTAIGLELHTDLPNWRHPPDIQLLYCLENEAEGGE
SLFADGFAVAEALRHEAPELFLRLRDTPIDFRFQDEDSDIAVRAPVIEVDDTGRIREVRFNNWIRDTLRLPPEEADAWYE
AYLVFWQRLREPRFRVDFALEPGQMVAFDNRRVLHGRGAFDPNTGRRHLQGTYLDIDHLESHLRVLARHATSAAPDTPTT
STNETGVS
>Mature_408_residues
MQSQSQSPAVEMSELFPYAQGPALRTSQAHDKALEIIWENADSARFSYRWLRDHCACPECRHPMTRERLYMPLEDENFLN
ARPEASVEDGVLVLRWADGHESRFDAGWLHQRRPESRIDDGVPRAEAWREGFTPAHVPHAEMMGGHEGRREWLTALLRDG
LVLLDDGPRELEEVVRIAELFGPMRATNFGARFDVQSKPNPNNAAYTAIGLELHTDLPNWRHPPDIQLLYCLENEAEGGE
SLFADGFAVAEALRHEAPELFLRLRDTPIDFRFQDEDSDIAVRAPVIEVDDTGRIREVRFNNWIRDTLRLPPEEADAWYE
AYLVFWQRLREPRFRVDFALEPGQMVAFDNRRVLHGRGAFDPNTGRRHLQGTYLDIDHLESHLRVLARHATSAAPDTPTT
STNETGVS

Specific function: Catalyzes the formation of L-carnitine from gamma- butyrobetaine [H]

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-BBH/TMLD family [H]

Homologues:

Organism=Homo sapiens, GI4502369, Length=378, Percent_Identity=30.6878306878307, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI8922625, Length=375, Percent_Identity=29.3333333333333, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI296317249, Length=252, Percent_Identity=29.3650793650794, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17534641, Length=401, Percent_Identity=30.6733167082294, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI71992672, Length=389, Percent_Identity=26.4781491002571, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI19922166, Length=391, Percent_Identity=33.5038363171356, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI221329931, Length=375, Percent_Identity=33.6, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24639015, Length=379, Percent_Identity=31.6622691292876, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24648401, Length=360, Percent_Identity=27.2222222222222, Blast_Score=125, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012775
- InterPro:   IPR010376
- InterPro:   IPR003819 [H]

Pfam domain/function: PF06155 DUF971; PF02668 TauD [H]

EC number: =1.14.11.1 [H]

Molecular weight: Translated: 46775; Mature: 46775

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSQSQSPAVEMSELFPYAQGPALRTSQAHDKALEIIWENADSARFSYRWLRDHCACPEC
CCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHEEHHEECCCCCCHHHHHHHHHCCCCCHH
RHPMTRERLYMPLEDENFLNARPEASVEDGVLVLRWADGHESRFDAGWLHQRRPESRIDD
CCCCCHHHEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHCCCHHHHHC
GVPRAEAWREGFTPAHVPHAEMMGGHEGRREWLTALLRDGLVLLDDGPRELEEVVRIAEL
CCCHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHH
FGPMRATNFGARFDVQSKPNPNNAAYTAIGLELHTDLPNWRHPPDIQLLYCLENEAEGGE
HCCHHHCCCCCEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCC
SLFADGFAVAEALRHEAPELFLRLRDTPIDFRFQDEDSDIAVRAPVIEVDDTGRIREVRF
HHHHHHHHHHHHHHHCCHHHEEEECCCCCCEEECCCCCCEEEECCEEEECCCCCEEEEHH
NNWIRDTLRLPPEEADAWYEAYLVFWQRLREPRFRVDFALEPGQMVAFDNRRVLHGRGAF
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCEEEECCCCC
DPNTGRRHLQGTYLDIDHLESHLRVLARHATSAAPDTPTTSTNETGVS
CCCCCCHHCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQSQSQSPAVEMSELFPYAQGPALRTSQAHDKALEIIWENADSARFSYRWLRDHCACPEC
CCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHEEHHEECCCCCCHHHHHHHHHCCCCCHH
RHPMTRERLYMPLEDENFLNARPEASVEDGVLVLRWADGHESRFDAGWLHQRRPESRIDD
CCCCCHHHEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHCCCHHHHHC
GVPRAEAWREGFTPAHVPHAEMMGGHEGRREWLTALLRDGLVLLDDGPRELEEVVRIAEL
CCCHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHH
FGPMRATNFGARFDVQSKPNPNNAAYTAIGLELHTDLPNWRHPPDIQLLYCLENEAEGGE
HCCHHHCCCCCEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCC
SLFADGFAVAEALRHEAPELFLRLRDTPIDFRFQDEDSDIAVRAPVIEVDDTGRIREVRF
HHHHHHHHHHHHHHHCCHHHEEEECCCCCCEEECCCCCCEEEECCEEEECCCCCEEEEHH
NNWIRDTLRLPPEEADAWYEAYLVFWQRLREPRFRVDFALEPGQMVAFDNRRVLHGRGAF
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCEEEECCCCC
DPNTGRRHLQGTYLDIDHLESHLRVLARHATSAAPDTPTTSTNETGVS
CCCCCCHHCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8504802 [H]