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The map label for this gene is lrp [H]

Identifier: 92114634

GI number: 92114634

Start: 2822537

End: 2823046

Strand: Direct

Name: lrp [H]

Synonym: Csal_2516

Alternate gene names: 92114634

Gene position: 2822537-2823046 (Clockwise)

Preceding gene: 92114632

Following gene: 92114635

Centisome position: 76.35

GC content: 63.92

Gene sequence:

>510_bases
ATGCCAAACAGCAACGCCCAGGCCGCCAACGTGACGCTCGATCGCTACGACCGTCAAATTCTCGACATCCTGCAACGCCA
CGGACGCATCAATAATCAGGAGCTGGCCGAACGCATCGGCCTGTCGCCCTCCCCCTGCCTGCGGCGCGTGCGGGCCCTGG
AAGACAACGGCCTGATCACCGGCTATCGTGCCCTGGTGGACGCCAAGCGGCTGGGCCATAGCCTCACCGCGCTATTGCAT
ATCTCCATGGACCGCCATACCCCGGAGCGTTTCGCCAACTTCGAGGCCAAGGTCGCGGCACTGCCCCAGGTTCAGGAATG
CCTGCTGATCACCGGCCAGGAGGCCGACTACCAACTCAAGGTCGTGGTACACGACATGGACGACTACCAGAACCTGCTGC
TCAACCAGATCACCCGCATCGAAGGCGTCACTGGCGCGCACTCGAGCTTCGTCCTGCGTCGAGTGCTCGAGCATCGCCCG
GTGCCCTCGTATCCCGCCGCCTCCCCGTGA

Upstream 100 bases:

>100_bases
CAGTTTACGTCGTCACTCCCCGCAGGGGATTGCAAACTCGACCTTCTTTCGCGTCACTTTTGGCATATAATTTTAACAAA
ACATCGTGAAGAGACATTTC

Downstream 100 bases:

>100_bases
GGAGGGCCATTAGACACTGGTGCAATGGTCGGGTGACAGGAAGCCTGTTACGTTCTTTGTATGCAATAGTCATCTATCGA
CCAGGACACATGCCATGCAA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MPNSNAQAANVTLDRYDRQILDILQRHGRINNQELAERIGLSPSPCLRRVRALEDNGLITGYRALVDAKRLGHSLTALLH
ISMDRHTPERFANFEAKVAALPQVQECLLITGQEADYQLKVVVHDMDDYQNLLLNQITRIEGVTGAHSSFVLRRVLEHRP
VPSYPAASP

Sequences:

>Translated_169_residues
MPNSNAQAANVTLDRYDRQILDILQRHGRINNQELAERIGLSPSPCLRRVRALEDNGLITGYRALVDAKRLGHSLTALLH
ISMDRHTPERFANFEAKVAALPQVQECLLITGQEADYQLKVVVHDMDDYQNLLLNQITRIEGVTGAHSSFVLRRVLEHRP
VPSYPAASP
>Mature_168_residues
PNSNAQAANVTLDRYDRQILDILQRHGRINNQELAERIGLSPSPCLRRVRALEDNGLITGYRALVDAKRLGHSLTALLHI
SMDRHTPERFANFEAKVAALPQVQECLLITGQEADYQLKVVVHDMDDYQNLLLNQITRIEGVTGAHSSFVLRRVLEHRPV
PSYPAASP

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=44.7552447552448, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=32, Blast_Score=95, Evalue=2e-21,
Organism=Escherichia coli, GI1790182, Length=144, Percent_Identity=29.8611111111111, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18997; Mature: 18866

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNSNAQAANVTLDRYDRQILDILQRHGRINNQELAERIGLSPSPCLRRVRALEDNGLIT
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCH
GYRALVDAKRLGHSLTALLHISMDRHTPERFANFEAKVAALPQVQECLLITGQEADYQLK
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHCHHHHHHHEECCCCCCEEEE
VVVHDMDDYQNLLLNQITRIEGVTGAHSSFVLRRVLEHRPVPSYPAASP
EEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PNSNAQAANVTLDRYDRQILDILQRHGRINNQELAERIGLSPSPCLRRVRALEDNGLIT
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCH
GYRALVDAKRLGHSLTALLHISMDRHTPERFANFEAKVAALPQVQECLLITGQEADYQLK
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHCHHHHHHHEECCCCCCEEEE
VVVHDMDDYQNLLLNQITRIEGVTGAHSSFVLRRVLEHRPVPSYPAASP
EEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]