| Definition | Chromohalobacter salexigens DSM 3043 chromosome, complete genome. |
|---|---|
| Accession | NC_007963 |
| Length | 3,696,649 |
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The map label for this gene is entA [C]
Identifier: 92114574
GI number: 92114574
Start: 2762346
End: 2763113
Strand: Direct
Name: entA [C]
Synonym: Csal_2456
Alternate gene names: 92114574
Gene position: 2762346-2763113 (Clockwise)
Preceding gene: 92114573
Following gene: 92114575
Centisome position: 74.73
GC content: 68.75
Gene sequence:
>768_bases ATGACATTCACCGGTCAACGCGTGCTGGTGACCGGCGGCGCCCGCGGTATCGGCGCCGCCACGGCACGGCGCTTTCTCGA ACAGGGGGCGCGCGTCGCCATCGGCGCGCGCCGAGAGGCCTCCGTCGAGGCGTTCCGCGATTCGCTGGCGAATACCGAGC TTGCCTCGGCCACGGTGGAATCCGCCGTGGGCGAGATCGGCACCCAGGCCGAGTGCCGGGCGGTCGTGGAAACTGCCGTC GCGCGCCTCGGTGGGCTCGACATTCTGGTCAATTGCGCCGGCGTCTTCGAGGAAGTGCCCTTCGAAGCGGTCACGCAGGA ACACTGGGACAGCACGTTCCGCGTCAACGTGGGCGGCACCTTCTTCTGCCTCCAGGCGGCGCTACCGCACCTGGAGGCCA GTGGCGGCAACGTCGTCAACCTGGGTTCGGATGCCGGCCTGATCGGCTTCCCACCGAGCAGCGTCTACTCCGGTGCCAAG GCCGCCGTGGTCAACCTGACCCGCGCCCTGGCCCTGGAGCTGGCCGGCCGCATACGGATCAACTGCGTGTGCCCGGGCAA TGTCGAGACCGACATGATTCAGCACGCCGCCGAGGCCAGCGGCGAGCCACACGCCTACCTGGACGCGGCCCATCGACGAG CGCCCCTGCAACGCATGGGAAAACCGCAAGAGATCGCCGATGCCGTGCTCTATCTCGCCTCTCCCCAGGCCGGCTTCACC CATGGCGCCATCCTGTCCGTCGACGGTGGCGGCGTGTGCGGCTTTTGA
Upstream 100 bases:
>100_bases CCGCACGCAGCAACGAAAGCGAGCATCTGGTGCTGCACTTCCACCGCCTGGTGTTCCAGGCCTTGCAGGGTGACGCCAGC ACGCCCCAGGAGGCGCCGTC
Downstream 100 bases:
>100_bases GCTCGCGCAGGCCCGCTCGCCGCACCTGACGGCAACACAACGACAACACATCACGAGGAGACTCCCATGACCGCTACCCC CCGACACCGCACCCCACTGG
Product: short-chain dehydrogenase/reductase SDR
Products: 2,3-Dihydroxybenzoate; H+; Nicotinamide adenine dinucleotide - reduced [C]
Alternate protein names: NA
Number of amino acids: Translated: 255; Mature: 254
Protein sequence:
>255_residues MTFTGQRVLVTGGARGIGAATARRFLEQGARVAIGARREASVEAFRDSLANTELASATVESAVGEIGTQAECRAVVETAV ARLGGLDILVNCAGVFEEVPFEAVTQEHWDSTFRVNVGGTFFCLQAALPHLEASGGNVVNLGSDAGLIGFPPSSVYSGAK AAVVNLTRALALELAGRIRINCVCPGNVETDMIQHAAEASGEPHAYLDAAHRRAPLQRMGKPQEIADAVLYLASPQAGFT HGAILSVDGGGVCGF
Sequences:
>Translated_255_residues MTFTGQRVLVTGGARGIGAATARRFLEQGARVAIGARREASVEAFRDSLANTELASATVESAVGEIGTQAECRAVVETAV ARLGGLDILVNCAGVFEEVPFEAVTQEHWDSTFRVNVGGTFFCLQAALPHLEASGGNVVNLGSDAGLIGFPPSSVYSGAK AAVVNLTRALALELAGRIRINCVCPGNVETDMIQHAAEASGEPHAYLDAAHRRAPLQRMGKPQEIADAVLYLASPQAGFT HGAILSVDGGGVCGF >Mature_254_residues TFTGQRVLVTGGARGIGAATARRFLEQGARVAIGARREASVEAFRDSLANTELASATVESAVGEIGTQAECRAVVETAVA RLGGLDILVNCAGVFEEVPFEAVTQEHWDSTFRVNVGGTFFCLQAALPHLEASGGNVVNLGSDAGLIGFPPSSVYSGAKA AVVNLTRALALELAGRIRINCVCPGNVETDMIQHAAEASGEPHAYLDAAHRRAPLQRMGKPQEIADAVLYLASPQAGFTH GAILSVDGGGVCGF
Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=34.375, Blast_Score=124, Evalue=1e-28, Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=33.8709677419355, Blast_Score=113, Evalue=1e-25, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=34.2857142857143, Blast_Score=111, Evalue=7e-25, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=33.1967213114754, Blast_Score=107, Evalue=9e-24, Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=31.7796610169492, Blast_Score=107, Evalue=9e-24, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=33.4661354581673, Blast_Score=101, Evalue=7e-22, Organism=Homo sapiens, GI66933014, Length=168, Percent_Identity=33.9285714285714, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI15277342, Length=167, Percent_Identity=34.1317365269461, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=36.7567567567568, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=32.0158102766798, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI31542939, Length=259, Percent_Identity=29.3436293436293, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=27.843137254902, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI126723191, Length=187, Percent_Identity=34.7593582887701, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI4504505, Length=237, Percent_Identity=29.1139240506329, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI142976729, Length=203, Percent_Identity=28.0788177339901, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=28.8, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI224922801, Length=176, Percent_Identity=30.6818181818182, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI40254986, Length=191, Percent_Identity=26.7015706806283, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI4503817, Length=196, Percent_Identity=27.5510204081633, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=26.2626262626263, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI210032110, Length=191, Percent_Identity=27.7486910994764, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1787335, Length=252, Percent_Identity=32.5396825396825, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=31.1023622047244, Blast_Score=114, Evalue=5e-27, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=31.2252964426877, Blast_Score=110, Evalue=8e-26, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=32.258064516129, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=32.9317269076305, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=30.6772908366534, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=32.4110671936759, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=29.5275590551181, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI1789208, Length=180, Percent_Identity=30.5555555555556, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=27.843137254902, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1787820, Length=187, Percent_Identity=31.0160427807487, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1789057, Length=264, Percent_Identity=28.030303030303, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1788891, Length=193, Percent_Identity=30.5699481865285, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787526, Length=228, Percent_Identity=26.7543859649123, Blast_Score=62, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=32.9365079365079, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI71994604, Length=243, Percent_Identity=30.8641975308642, Blast_Score=121, Evalue=3e-28, Organism=Caenorhabditis elegans, GI71994600, Length=244, Percent_Identity=30.7377049180328, Blast_Score=121, Evalue=4e-28, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=32.5670498084291, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=32.8063241106719, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=31.6205533596838, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=28.1368821292776, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=30.8880308880309, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=29.7619047619048, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=32.6693227091633, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=30.5343511450382, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=31.2741312741313, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=27.4131274131274, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=28.1853281853282, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562990, Length=256, Percent_Identity=28.515625, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=30.5343511450382, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=28.6259541984733, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI72000259, Length=256, Percent_Identity=28.90625, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=26.7924528301887, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=29.296875, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=29.9242424242424, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=28.3524904214559, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=28.1954887218045, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17562908, Length=258, Percent_Identity=28.2945736434109, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17551412, Length=259, Percent_Identity=27.4131274131274, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17568967, Length=191, Percent_Identity=29.8429319371728, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=31.0344827586207, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17536651, Length=261, Percent_Identity=28.3524904214559, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17508895, Length=206, Percent_Identity=26.2135922330097, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71982365, Length=148, Percent_Identity=30.4054054054054, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=26.7676767676768, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=27.319587628866, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=239, Percent_Identity=30.5439330543933, Blast_Score=89, Evalue=5e-19, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=26.4, Blast_Score=83, Evalue=5e-17, Organism=Saccharomyces cerevisiae, GI6322861, Length=243, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=3e-15, Organism=Saccharomyces cerevisiae, GI6322226, Length=202, Percent_Identity=30.1980198019802, Blast_Score=72, Evalue=9e-14, Organism=Saccharomyces cerevisiae, GI6322227, Length=209, Percent_Identity=28.2296650717703, Blast_Score=67, Evalue=3e-12, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=35.0597609561753, Blast_Score=139, Evalue=2e-33, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=33.7301587301587, Blast_Score=137, Evalue=6e-33, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=33.6, Blast_Score=125, Evalue=3e-29, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=31.2, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=30.8880308880309, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=34.5381526104418, Blast_Score=104, Evalue=6e-23, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=29.6442687747036, Blast_Score=103, Evalue=9e-23, Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=33.201581027668, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24665243, Length=259, Percent_Identity=30.5019305019305, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI221331218, Length=256, Percent_Identity=30.46875, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI221331216, Length=257, Percent_Identity=30.3501945525292, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI24665247, Length=260, Percent_Identity=30.3846153846154, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=29.6875, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI281364494, Length=248, Percent_Identity=29.0322580645161, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI18859837, Length=195, Percent_Identity=28.2051282051282, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI116007236, Length=238, Percent_Identity=24.3697478991597, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24656154, Length=212, Percent_Identity=27.8301886792453, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI19922628, Length=212, Percent_Identity=27.8301886792453, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI21357673, Length=234, Percent_Identity=24.7863247863248, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21358495, Length=212, Percent_Identity=25.9433962264151, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24581726, Length=232, Percent_Identity=25.4310344827586, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI281364892, Length=202, Percent_Identity=28.2178217821782, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.3.1.28 [C]
Molecular weight: Translated: 26404; Mature: 26273
Theoretical pI: Translated: 5.31; Mature: 5.31
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.4 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 2.4 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTFTGQRVLVTGGARGIGAATARRFLEQGARVAIGARREASVEAFRDSLANTELASATVE CCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHH SAVGEIGTQAECRAVVETAVARLGGLDILVNCAGVFEEVPFEAVTQEHWDSTFRVNVGGT HHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCH FFCLQAALPHLEASGGNVVNLGSDAGLIGFPPSSVYSGAKAAVVNLTRALALELAGRIRI HHHHHHHCCCCCCCCCCEEEECCCCCEEECCCHHHHCCCHHHHHHHHHHHHHHHCCCEEE NCVCPGNVETDMIQHAAEASGEPHAYLDAAHRRAPLQRMGKPQEIADAVLYLASPQAGFT EEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHHCCCCCCCC HGAILSVDGGGVCGF CCEEEEECCCCCCCC >Mature Secondary Structure TFTGQRVLVTGGARGIGAATARRFLEQGARVAIGARREASVEAFRDSLANTELASATVE CCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHH SAVGEIGTQAECRAVVETAVARLGGLDILVNCAGVFEEVPFEAVTQEHWDSTFRVNVGGT HHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCH FFCLQAALPHLEASGGNVVNLGSDAGLIGFPPSSVYSGAKAAVVNLTRALALELAGRIRI HHHHHHHCCCCCCCCCCEEEECCCCCEEECCCHHHHCCCHHHHHHHHHHHHHHHCCCEEE NCVCPGNVETDMIQHAAEASGEPHAYLDAAHRRAPLQRMGKPQEIADAVLYLASPQAGFT EEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHHCCCCCCCC HGAILSVDGGGVCGF CCEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NAD+ [C]
Metal ions: NA
Kcat value (1/min): 5550 [C]
Specific activity: 66
Km value (mM): 0.26 {methyl-2,3-dehydro-3-hydroxybenzoate}} 0.2 {3-oxocyclohexane-1-carboxylic} 0.3 {2,3-dihydro-2,3-dihydroxybenzoate}} [C]
Substrates: 2,3-Dihydro-2,3-dihydroxybenzoate; Nicotinamide adenine dinucleotide [C]
Specific reaction: 2,3-Dihydro-2,3-dihydroxybenzoate + Nicotinamide adenine dinucleotide <==> 2,3-Dihydroxybenzoate + H+ + Nicotinamide adenine dinucleotide - reduced [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]