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The map label for this gene is pabB [H]

Identifier: 92114542

GI number: 92114542

Start: 2727150

End: 2728496

Strand: Direct

Name: pabB [H]

Synonym: Csal_2424

Alternate gene names: 92114542

Gene position: 2727150-2728496 (Clockwise)

Preceding gene: 92114528

Following gene: 92114543

Centisome position: 73.77

GC content: 66.37

Gene sequence:

>1347_bases
ATGACGCCAACACTCGAACAGACTCCTCTGCCCTATCATGCCGATCCGCTGACACGCTTCGAGCGACTGCGCCAGCGCCC
CCATGCCGTGCTTCTGGACAGCGGTTTTCCGGCGGCCCCCGGCGGACGTTACGATATCATCAGCAGCGATCCCGTCGCCT
GGCTCGAGATCGATCGTCACGGGCGGGCGATCAGCAACGTCAAGGACCTGCCCGACGCCCCGCTGGATGCTCAGCGTGCA
CTGCTGGAGCGACTGCCCGAGCCCGCCCTGGCAAGCGAGCTGCCGTTTCTCGGCGGCCTGATCGGTTATTGGAGCTATGA
CTTCGGCCGCCACCTGGAATCCTTGCCGGACACCGCCCGCGAAGCGGTGACGCTCCCTCATAGTCGGGTCGGCCTCTACG
ACTGGGCGATCGTTCACGATCATCAGGCACGGCATGCCTGGCTCGTGGCCACGCCGGAAAGGCGCGCGCAGGTCCTGGCA
TGGCTGCAGGACACGCCGCCGCCAGCGGCGCCATTCACGCTGCTCTCGGCCTTTCGGAGCGAATGGAACCGCCAGGCATA
CGGCGAGCGCTTCCGCGCCGTGCAGCATTACATTCGCAGCGGCGACTGCTACCAGATCAATCTTGCCCAGCGTTTCAGCG
CCGCCTATCGCGGCGATCTCTGGCAAGCCTATCGGCGCCTCCGTGCCGCCACGCCGACACCGTACGGCGCCTACCTGGCC
TGGGGCGATCAGGGCATCCTGTCGCTATCGCCGGAGCGCTTTCTGCGGGTCGAAGGCACGCAGGTGGAAGCCCGCCCCAT
CAAGGGCACGCGCCCGCGCGGGCAGACGCCCTGGCAGGACCGCCAGTACGCGCATGAACTGCGCCACAGTCTCAAGGACA
CCGCCGAGAACGTCATGATCGTCGACCTGTTGCGCAACGATCTGGGACGGGTATGTCGACCGGGAAGCGTGCGTGTGCCG
CAACTGTGCGGTCTCGAAAGCTACGCCAACGTGCACCATCTGGTCAGTGTCATCACCGGCGAACTGACCGCCGATCAGCA
CGCCCTGGACTTGCTGGGCGCGGCCTTTCCGGGCGGGTCGATCACCGGTGCGCCCAAGGTTCGCGCCATGCAGCTCATTG
ACGCGCTCGAGCCCAGTCGACGCAGCGTGTACTGCGGCAGCATCGGCTACGTGGACGTTCGGGGCCACATGGACACCTCC
ATCGCGATCCGTACCGCCGTGGCCGATGCCGGCCACCTGCATCTCTGGGGCGGCGGCGGCCTGGTCGCGGATTCCGACGA
GGAAGCCGAATATCAGGAGACCCTGGCCAAGATCACACGTCTGATGGACGCCTTGACCGGCGACTGA

Upstream 100 bases:

>100_bases
GGCAAATCGATGAGTTCGGCTCGAAATCCGTTGCTCTCGCGGCGACCGATCACGCCTTACAGGCTGTTAGAATAAGCCGC
TCGCGAAAGGAAGCCAGTGC

Downstream 100 bases:

>100_bases
CACCGCATGCTCCGGGGGAATCGCGTATCCTGAGGGCGCCCATACATCGCTATACGCCGACGCCATGACACATGCATCGC
CCGCCACCGCCAATGCCGAC

Product: aminodeoxychorismate synthase, subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MTPTLEQTPLPYHADPLTRFERLRQRPHAVLLDSGFPAAPGGRYDIISSDPVAWLEIDRHGRAISNVKDLPDAPLDAQRA
LLERLPEPALASELPFLGGLIGYWSYDFGRHLESLPDTAREAVTLPHSRVGLYDWAIVHDHQARHAWLVATPERRAQVLA
WLQDTPPPAAPFTLLSAFRSEWNRQAYGERFRAVQHYIRSGDCYQINLAQRFSAAYRGDLWQAYRRLRAATPTPYGAYLA
WGDQGILSLSPERFLRVEGTQVEARPIKGTRPRGQTPWQDRQYAHELRHSLKDTAENVMIVDLLRNDLGRVCRPGSVRVP
QLCGLESYANVHHLVSVITGELTADQHALDLLGAAFPGGSITGAPKVRAMQLIDALEPSRRSVYCGSIGYVDVRGHMDTS
IAIRTAVADAGHLHLWGGGGLVADSDEEAEYQETLAKITRLMDALTGD

Sequences:

>Translated_448_residues
MTPTLEQTPLPYHADPLTRFERLRQRPHAVLLDSGFPAAPGGRYDIISSDPVAWLEIDRHGRAISNVKDLPDAPLDAQRA
LLERLPEPALASELPFLGGLIGYWSYDFGRHLESLPDTAREAVTLPHSRVGLYDWAIVHDHQARHAWLVATPERRAQVLA
WLQDTPPPAAPFTLLSAFRSEWNRQAYGERFRAVQHYIRSGDCYQINLAQRFSAAYRGDLWQAYRRLRAATPTPYGAYLA
WGDQGILSLSPERFLRVEGTQVEARPIKGTRPRGQTPWQDRQYAHELRHSLKDTAENVMIVDLLRNDLGRVCRPGSVRVP
QLCGLESYANVHHLVSVITGELTADQHALDLLGAAFPGGSITGAPKVRAMQLIDALEPSRRSVYCGSIGYVDVRGHMDTS
IAIRTAVADAGHLHLWGGGGLVADSDEEAEYQETLAKITRLMDALTGD
>Mature_447_residues
TPTLEQTPLPYHADPLTRFERLRQRPHAVLLDSGFPAAPGGRYDIISSDPVAWLEIDRHGRAISNVKDLPDAPLDAQRAL
LERLPEPALASELPFLGGLIGYWSYDFGRHLESLPDTAREAVTLPHSRVGLYDWAIVHDHQARHAWLVATPERRAQVLAW
LQDTPPPAAPFTLLSAFRSEWNRQAYGERFRAVQHYIRSGDCYQINLAQRFSAAYRGDLWQAYRRLRAATPTPYGAYLAW
GDQGILSLSPERFLRVEGTQVEARPIKGTRPRGQTPWQDRQYAHELRHSLKDTAENVMIVDLLRNDLGRVCRPGSVRVPQ
LCGLESYANVHHLVSVITGELTADQHALDLLGAAFPGGSITGAPKVRAMQLIDALEPSRRSVYCGSIGYVDVRGHMDTSI
AIRTAVADAGHLHLWGGGGLVADSDEEAEYQETLAKITRLMDALTGD

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=431, Percent_Identity=48.7238979118329, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1787518, Length=393, Percent_Identity=35.6234096692112, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1786809, Length=221, Percent_Identity=27.6018099547511, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082077, Length=200, Percent_Identity=28, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=371, Percent_Identity=36.3881401617251, Blast_Score=210, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6324361, Length=399, Percent_Identity=27.0676691729323, Blast_Score=137, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 49844; Mature: 49713

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTLEQTPLPYHADPLTRFERLRQRPHAVLLDSGFPAAPGGRYDIISSDPVAWLEIDRH
CCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCEEEEEECCC
GRAISNVKDLPDAPLDAQRALLERLPEPALASELPFLGGLIGYWSYDFGRHLESLPDTAR
CCHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHH
EAVTLPHSRVGLYDWAIVHDHQARHAWLVATPERRAQVLAWLQDTPPPAAPFTLLSAFRS
HHCCCCCCCCCCEEEEEEECCCCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EWNRQAYGERFRAVQHYIRSGDCYQINLAQRFSAAYRGDLWQAYRRLRAATPTPYGAYLA
HHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
WGDQGILSLSPERFLRVEGTQVEARPIKGTRPRGQTPWQDRQYAHELRHSLKDTAENVMI
ECCCCCEEECHHHEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEH
VDLLRNDLGRVCRPGSVRVPQLCGLESYANVHHLVSVITGELTADQHALDLLGAAFPGGS
HHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
ITGAPKVRAMQLIDALEPSRRSVYCGSIGYVDVRGHMDTSIAIRTAVADAGHLHLWGGGG
CCCCCHHHHHHHHHHCCCCCCEEEECCCCEEEECCCCCCCEEEEEECCCCCEEEEEECCC
LVADSDEEAEYQETLAKITRLMDALTGD
EECCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPTLEQTPLPYHADPLTRFERLRQRPHAVLLDSGFPAAPGGRYDIISSDPVAWLEIDRH
CCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCEEEEEECCC
GRAISNVKDLPDAPLDAQRALLERLPEPALASELPFLGGLIGYWSYDFGRHLESLPDTAR
CCHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHH
EAVTLPHSRVGLYDWAIVHDHQARHAWLVATPERRAQVLAWLQDTPPPAAPFTLLSAFRS
HHCCCCCCCCCCEEEEEEECCCCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EWNRQAYGERFRAVQHYIRSGDCYQINLAQRFSAAYRGDLWQAYRRLRAATPTPYGAYLA
HHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
WGDQGILSLSPERFLRVEGTQVEARPIKGTRPRGQTPWQDRQYAHELRHSLKDTAENVMI
ECCCCCEEECHHHEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEH
VDLLRNDLGRVCRPGSVRVPQLCGLESYANVHHLVSVITGELTADQHALDLLGAAFPGGS
HHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
ITGAPKVRAMQLIDALEPSRRSVYCGSIGYVDVRGHMDTSIAIRTAVADAGHLHLWGGGG
CCCCCHHHHHHHHHHCCCCCCEEEECCCCEEEECCCCCCCEEEEEECCCCCEEEEEECCC
LVADSDEEAEYQETLAKITRLMDALTGD
EECCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]