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The map label for this gene is corC [H]

Identifier: 92114458

GI number: 92114458

Start: 2626985

End: 2627875

Strand: Direct

Name: corC [H]

Synonym: Csal_2337

Alternate gene names: 92114458

Gene position: 2626985-2627875 (Clockwise)

Preceding gene: 92114457

Following gene: 92114459

Centisome position: 71.06

GC content: 62.96

Gene sequence:

>891_bases
ATGAGCGAAGACCGATCGAGCAGCCAGGGTGGCAAGTCCTGGCTGGATAAACTGTTGAGCGCTTTCTCCAACGACGCCGA
CGAGCCCAGCTCGCGAGACGAACTGCTCACCTTCCTGCGCGAGGCCGGCACCCGGCTACGCCTCGATCAGGATGCGCTGA
CCATCATCGAGGGCGCATTCCAGATCAGCGATCAGCAAACCCGTGAGGTGATGATCCCGCGCTCCCAGGTAACCGCCCTG
CATGTCGATCAACGCCCCGAGGACTGCCTGCCGGTGATCCTCGAAACCGCTCACTCGCGCTACCCGGTCATCGACGAAAA
CCTCGATGAAGTGCTGGGCATCGTGCTGGTCAAGGACCTGCTGCCCTTGCTCAAGCTCAGCGATGCCGAGCGCCAGCGCT
TTCAACTGCGCGACATCCTGCGTCCGGCGATGTTCATTCCCGAGTCGAAGCGGCTCAACAGCCTGCTCAAGGAATTCCGC
GACACCCACAACCACATGGCGGTGGTGGTCGACGAATACGGCGGTACCGCCGGCATCGTGACCATCGAGGACATCCTCGA
GCAGATCGTCGGCGATATCGAAGACGAGCACGACACCGACGAGGAAGACGACATCCGCGACCTCGGCGACGGCACCTACG
CGATTCGTGCGCTGACCCCCATCGAGGAGTTCAACGAACGCTTCGACACGGCCTTCCCCGACGAGGAATTCGACACCGTC
GGCGGCCTGGTGATGCAGCGCTTCGGCCATCTTCCCCGTCGCAACGAATACGCCGACCTGGGCGACTGGCGCTTCACCGT
GCTCAACGCCGACAACCGCCGCATCCGGCTGTTGCAGGTCTCGCCCGCATCGGATGCCAGCAGCGAGACGGCGCAAGCCG
AAAGGGAATGA

Upstream 100 bases:

>100_bases
GCCGGAACGGCCCCCGGCTTCCTCCGAAACGCGACCGCCGGCCGCGTCAGCATCTTATTACCCCAGCGTGATCGTCCATG
AGGAACGAGAGACCCATCGC

Downstream 100 bases:

>100_bases
CCCCAAGTGCGCCGTGACGCCGTGTCGTCCTCGTTGCGGCATGGCCCACGGCGCCCTGCTCTGTTATAAGAGGCACCTTC
GACAAGGAGTGCCTCATGCT

Product: putative metal ion transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSEDRSSSQGGKSWLDKLLSAFSNDADEPSSRDELLTFLREAGTRLRLDQDALTIIEGAFQISDQQTREVMIPRSQVTAL
HVDQRPEDCLPVILETAHSRYPVIDENLDEVLGIVLVKDLLPLLKLSDAERQRFQLRDILRPAMFIPESKRLNSLLKEFR
DTHNHMAVVVDEYGGTAGIVTIEDILEQIVGDIEDEHDTDEEDDIRDLGDGTYAIRALTPIEEFNERFDTAFPDEEFDTV
GGLVMQRFGHLPRRNEYADLGDWRFTVLNADNRRIRLLQVSPASDASSETAQAERE

Sequences:

>Translated_296_residues
MSEDRSSSQGGKSWLDKLLSAFSNDADEPSSRDELLTFLREAGTRLRLDQDALTIIEGAFQISDQQTREVMIPRSQVTAL
HVDQRPEDCLPVILETAHSRYPVIDENLDEVLGIVLVKDLLPLLKLSDAERQRFQLRDILRPAMFIPESKRLNSLLKEFR
DTHNHMAVVVDEYGGTAGIVTIEDILEQIVGDIEDEHDTDEEDDIRDLGDGTYAIRALTPIEEFNERFDTAFPDEEFDTV
GGLVMQRFGHLPRRNEYADLGDWRFTVLNADNRRIRLLQVSPASDASSETAQAERE
>Mature_295_residues
SEDRSSSQGGKSWLDKLLSAFSNDADEPSSRDELLTFLREAGTRLRLDQDALTIIEGAFQISDQQTREVMIPRSQVTALH
VDQRPEDCLPVILETAHSRYPVIDENLDEVLGIVLVKDLLPLLKLSDAERQRFQLRDILRPAMFIPESKRLNSLLKEFRD
THNHMAVVVDEYGGTAGIVTIEDILEQIVGDIEDEHDTDEEDDIRDLGDGTYAIRALTPIEEFNERFDTAFPDEEFDTVG
GLVMQRFGHLPRRNEYADLGDWRFTVLNADNRRIRLLQVSPASDASSETAQAERE

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=197, Percent_Identity=34.010152284264, Blast_Score=120, Evalue=1e-27,
Organism=Escherichia coli, GI1786879, Length=290, Percent_Identity=48.6206896551724, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI145693175, Length=266, Percent_Identity=24.4360902255639, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082033, Length=287, Percent_Identity=26.4808362369338, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788119, Length=236, Percent_Identity=28.8135593220339, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790664, Length=231, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33627; Mature: 33496

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDRSSSQGGKSWLDKLLSAFSNDADEPSSRDELLTFLREAGTRLRLDQDALTIIEGAF
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHH
QISDQQTREVMIPRSQVTALHVDQRPEDCLPVILETAHSRYPVIDENLDEVLGIVLVKDL
HCCCHHHHHHCCCHHHEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LPLLKLSDAERQRFQLRDILRPAMFIPESKRLNSLLKEFRDTHNHMAVVVDEYGGTAGIV
HHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
TIEDILEQIVGDIEDEHDTDEEDDIRDLGDGTYAIRALTPIEEFNERFDTAFPDEEFDTV
EHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHH
GGLVMQRFGHLPRRNEYADLGDWRFTVLNADNRRIRLLQVSPASDASSETAQAERE
HHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHCCCC
>Mature Secondary Structure 
SEDRSSSQGGKSWLDKLLSAFSNDADEPSSRDELLTFLREAGTRLRLDQDALTIIEGAF
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHH
QISDQQTREVMIPRSQVTALHVDQRPEDCLPVILETAHSRYPVIDENLDEVLGIVLVKDL
HCCCHHHHHHCCCHHHEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LPLLKLSDAERQRFQLRDILRPAMFIPESKRLNSLLKEFRDTHNHMAVVVDEYGGTAGIV
HHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
TIEDILEQIVGDIEDEHDTDEEDDIRDLGDGTYAIRALTPIEEFNERFDTAFPDEEFDTV
EHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHH
GGLVMQRFGHLPRRNEYADLGDWRFTVLNADNRRIRLLQVSPASDASSETAQAERE
HHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]