Click here to switch to the map view.

The map label for this gene is ndh [H]

Identifier: 92114446

GI number: 92114446

Start: 2614198

End: 2615496

Strand: Direct

Name: ndh [H]

Synonym: Csal_2325

Alternate gene names: 92114446

Gene position: 2614198-2615496 (Clockwise)

Preceding gene: 92114443

Following gene: 92114447

Centisome position: 70.72

GC content: 65.74

Gene sequence:

>1299_bases
ATGTCTACACCGCGCATCGTGGTGGTCGGGGGAGGCGCAGGTGGCCTCGAACTGGTCACCCGCCTGGGGCGCAAGCTCGG
CAAGCGCCAACGCGCCGAGATCGTTCTGGTCGACCGCAACGCCACGCACATCTGGAAGCCCCTGCTGCATGAAGTGGCCA
CGGGCGTGCTCGATTCCAGCCTCGATGAAGTGTCCTACCAGGGGCATTCCAAGGCGCACGGCTACCGCTTTCAACGCGGC
ACGCTCAGCAACCTCGACCGCGACAACCGCACCATCACGCTGGCGCCGATCATCGACGACGACGGCGTCGTGATCCTGCC
GGCGCGCACGCTGGAGTACGATTACCTGGTGATGTCTCTGGGCAGCGTCTCCAACGACTTCGGCACTCCGGGCGTGGCCA
AGCACAGCCACTTCATCGACAGCCCGCAACAGGCCGAAAGCTTCCGCCAGGACATGCTCAACACCTTCCTACGGTACAGC
GATCCCGAGCGGCGTACCCATCCCAACCTGAGCGTGGGACTCGTCGGTGCCGGTGCCACCGGCGTCGAGCTGGCCGCCGA
ACTGATCGGCGCCTCCAAGATGCTGCACAGCTACGGGTTCACCGCCATGGACAGCGGCAAGCTGGAGATCCACCTCATCG
AGGCGGCACCGCGCATCCTGCCGGCACTGCCCGAGCGCATCAGCCGCGCCGTGCACCAGGAGCTGGAACGCCTGGGCGTG
CAGATCCATGTCGACACCCGCGTGACCTGCGCCGACGAGCACGGTTTCGTCACCGCCGACGAGACGCGCATCGCCACCGA
CCTCAACGTCTGGGCCGCCGGCATACGCGCGCCGGCCTTTCTGTCCGAACTGGGGCTTTCCACCGAGCGCAATCATCAGC
TCAAGGTGCATCAGACCCTGCAGAGCATCGACGACGATCGCATCTTCGCCTTCGGCGACTGCGCCTCCTGCCCGCAACCT
GACGACAAGCGCGTACCGCCGCGCGCCCAGGCCGCGCATCAGCAAGCCAGCCTGCTGTACCACAACCTGCGCGCGGCAAT
GGACGGCAAGCCCCTCAAGGATTTCGTCTTCCGCGATCGCGGCTCGCTGATCTCGCTGGCGCACTTCGATGCCGTGGGCA
GCCTGATGCGCGGCGCCTCGGCACGCAGCCTGTTCATCGAGGGGCGCCTGGCCAAGCTGTTCTATGCCTCGCTCTATCGC
ATGCACCAGCTGGCCATTCATGGCGCCTTGAAAACCGGCATGACCGTCATCGTCGACGGCCTCAACCGGTATCTGCGCCC
CCGCATGAAGTTGCACTAA

Upstream 100 bases:

>100_bases
CACGACACGCCTTCCCAGGCGCCTCGTACCTTGGCGTTTCGCTGCGATGCCCGACCCTGGCGACACCCTTTTTCCATGTT
TCGTTCTTCGGGAGTCCATC

Downstream 100 bases:

>100_bases
TCCGACCGGAGCACCATGATCGTGGCACTCACCGCGCGATCATGGAGCCCGCTCATGCAGCACTTCTTCAACGATGCCTC
TCGCGTGGTCGACGACGTTC

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSTPRIVVVGGGAGGLELVTRLGRKLGKRQRAEIVLVDRNATHIWKPLLHEVATGVLDSSLDEVSYQGHSKAHGYRFQRG
TLSNLDRDNRTITLAPIIDDDGVVILPARTLEYDYLVMSLGSVSNDFGTPGVAKHSHFIDSPQQAESFRQDMLNTFLRYS
DPERRTHPNLSVGLVGAGATGVELAAELIGASKMLHSYGFTAMDSGKLEIHLIEAAPRILPALPERISRAVHQELERLGV
QIHVDTRVTCADEHGFVTADETRIATDLNVWAAGIRAPAFLSELGLSTERNHQLKVHQTLQSIDDDRIFAFGDCASCPQP
DDKRVPPRAQAAHQQASLLYHNLRAAMDGKPLKDFVFRDRGSLISLAHFDAVGSLMRGASARSLFIEGRLAKLFYASLYR
MHQLAIHGALKTGMTVIVDGLNRYLRPRMKLH

Sequences:

>Translated_432_residues
MSTPRIVVVGGGAGGLELVTRLGRKLGKRQRAEIVLVDRNATHIWKPLLHEVATGVLDSSLDEVSYQGHSKAHGYRFQRG
TLSNLDRDNRTITLAPIIDDDGVVILPARTLEYDYLVMSLGSVSNDFGTPGVAKHSHFIDSPQQAESFRQDMLNTFLRYS
DPERRTHPNLSVGLVGAGATGVELAAELIGASKMLHSYGFTAMDSGKLEIHLIEAAPRILPALPERISRAVHQELERLGV
QIHVDTRVTCADEHGFVTADETRIATDLNVWAAGIRAPAFLSELGLSTERNHQLKVHQTLQSIDDDRIFAFGDCASCPQP
DDKRVPPRAQAAHQQASLLYHNLRAAMDGKPLKDFVFRDRGSLISLAHFDAVGSLMRGASARSLFIEGRLAKLFYASLYR
MHQLAIHGALKTGMTVIVDGLNRYLRPRMKLH
>Mature_431_residues
STPRIVVVGGGAGGLELVTRLGRKLGKRQRAEIVLVDRNATHIWKPLLHEVATGVLDSSLDEVSYQGHSKAHGYRFQRGT
LSNLDRDNRTITLAPIIDDDGVVILPARTLEYDYLVMSLGSVSNDFGTPGVAKHSHFIDSPQQAESFRQDMLNTFLRYSD
PERRTHPNLSVGLVGAGATGVELAAELIGASKMLHSYGFTAMDSGKLEIHLIEAAPRILPALPERISRAVHQELERLGVQ
IHVDTRVTCADEHGFVTADETRIATDLNVWAAGIRAPAFLSELGLSTERNHQLKVHQTLQSIDDDRIFAFGDCASCPQPD
DKRVPPRAQAAHQQASLLYHNLRAAMDGKPLKDFVFRDRGSLISLAHFDAVGSLMRGASARSLFIEGRLAKLFYASLYRM
HQLAIHGALKTGMTVIVDGLNRYLRPRMKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=435, Percent_Identity=53.5632183908046, Blast_Score=467, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6323515, Length=468, Percent_Identity=23.9316239316239, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6323794, Length=471, Percent_Identity=25.4777070063694, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320118, Length=453, Percent_Identity=23.3995584988962, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47609; Mature: 47478

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPRIVVVGGGAGGLELVTRLGRKLGKRQRAEIVLVDRNATHIWKPLLHEVATGVLDSS
CCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
LDEVSYQGHSKAHGYRFQRGTLSNLDRDNRTITLAPIIDDDGVVILPARTLEYDYLVMSL
HHHHHCCCCCCCCCEEECCCCHHCCCCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHH
GSVSNDFGTPGVAKHSHFIDSPQQAESFRQDMLNTFLRYSDPERRTHPNLSVGLVGAGAT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEEEEECCCH
GVELAAELIGASKMLHSYGFTAMDSGKLEIHLIEAAPRILPALPERISRAVHQELERLGV
HHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCE
QIHVDTRVTCADEHGFVTADETRIATDLNVWAAGIRAPAFLSELGLSTERNHQLKVHQTL
EEEECCEEEEECCCCEEEECCCEEEEHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHH
QSIDDDRIFAFGDCASCPQPDDKRVPPRAQAAHQQASLLYHNLRAAMDGKPLKDFVFRDR
HHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
GSLISLAHFDAVGSLMRGASARSLFIEGRLAKLFYASLYRMHQLAIHGALKTGMTVIVDG
CCEEEHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LNRYLRPRMKLH
HHHHHCCCCCCC
>Mature Secondary Structure 
STPRIVVVGGGAGGLELVTRLGRKLGKRQRAEIVLVDRNATHIWKPLLHEVATGVLDSS
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
LDEVSYQGHSKAHGYRFQRGTLSNLDRDNRTITLAPIIDDDGVVILPARTLEYDYLVMSL
HHHHHCCCCCCCCCEEECCCCHHCCCCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHH
GSVSNDFGTPGVAKHSHFIDSPQQAESFRQDMLNTFLRYSDPERRTHPNLSVGLVGAGAT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEEEEECCCH
GVELAAELIGASKMLHSYGFTAMDSGKLEIHLIEAAPRILPALPERISRAVHQELERLGV
HHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCE
QIHVDTRVTCADEHGFVTADETRIATDLNVWAAGIRAPAFLSELGLSTERNHQLKVHQTL
EEEECCEEEEECCCCEEEECCCEEEEHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHH
QSIDDDRIFAFGDCASCPQPDDKRVPPRAQAAHQQASLLYHNLRAAMDGKPLKDFVFRDR
HHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
GSLISLAHFDAVGSLMRGASARSLFIEGRLAKLFYASLYRMHQLAIHGALKTGMTVIVDG
CCEEEHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LNRYLRPRMKLH
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]