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The map label for this gene is lptA [H]

Identifier: 92114346

GI number: 92114346

Start: 2496083

End: 2496607

Strand: Direct

Name: lptA [H]

Synonym: Csal_2224

Alternate gene names: 92114346

Gene position: 2496083-2496607 (Clockwise)

Preceding gene: 92114345

Following gene: 92114347

Centisome position: 67.52

GC content: 66.48

Gene sequence:

>525_bases
ATGATGACACGAACCTTGACGGTCGCGCTGGCATGCGCGGCACTGGGCCTGGCCAGTCACGCGGCCCTGGCGCTGGAAAG
CGATGCCAGCCAGCCCATCGAGATCGCCGCCGACCAGTTGGATCTCGACGATAACGCCGGCACCGCCGTCTACACCGGCG
ACGTCGACATGCAGCAGGGCAGCATGCGCCTGACCGCGGCACGCGTGGAGATCGAGCGCAACGCGCAGGGCGAGGTCTCC
ACCGTCACCGCCCACGGCAGCGGTAGCGAGCGCGCCTATCTCGAGCAGAAGCCTTCACCGGACGAGCCGGTGGCCAAGGG
CTGGGGCGACACCGTGATCTATCATGCCGGCGAACGCCGCGTCGAACTCATCGATCGCGCTCAGCTTCACCAGGGCGGAG
ACACCTTCAACGGTGCCTATGTCGAATATTTCCTCGATCGCCGCCAGGTCCAGGCGCGCTCCGACGACGACGGTGAAGGC
GATCAGCGCGTGCGCATGACGCTGACCCCGCGCAATGACCAATGA

Upstream 100 bases:

>100_bases
GCGTGCGCGGCAATCGCTTCGACGCCTGGCTCGATACCGACCGTGCGCGCCTGACCGGCGACGTGCAAGGCCACCACCCA
CAGATTGCCGAGGACGACAC

Downstream 100 bases:

>100_bases
CACCCTCGACCTTTCGTTCACCAACGCCCTGGATGCGATGCCCATGAAGACCCTGAGTGCCGCCAACCTGGCCAAGAGTT
ACAAGGGCCGCCGCGTGGTC

Product: OstA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MMTRTLTVALACAALGLASHAALALESDASQPIEIAADQLDLDDNAGTAVYTGDVDMQQGSMRLTAARVEIERNAQGEVS
TVTAHGSGSERAYLEQKPSPDEPVAKGWGDTVIYHAGERRVELIDRAQLHQGGDTFNGAYVEYFLDRRQVQARSDDDGEG
DQRVRMTLTPRNDQ

Sequences:

>Translated_174_residues
MMTRTLTVALACAALGLASHAALALESDASQPIEIAADQLDLDDNAGTAVYTGDVDMQQGSMRLTAARVEIERNAQGEVS
TVTAHGSGSERAYLEQKPSPDEPVAKGWGDTVIYHAGERRVELIDRAQLHQGGDTFNGAYVEYFLDRRQVQARSDDDGEG
DQRVRMTLTPRNDQ
>Mature_174_residues
MMTRTLTVALACAALGLASHAALALESDASQPIEIAADQLDLDDNAGTAVYTGDVDMQQGSMRLTAARVEIERNAQGEVS
TVTAHGSGSERAYLEQKPSPDEPVAKGWGDTVIYHAGERRVELIDRAQLHQGGDTFNGAYVEYFLDRRQVQARSDDDGEG
DQRVRMTLTPRNDQ

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 18878; Mature: 18878

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTRTLTVALACAALGLASHAALALESDASQPIEIAADQLDLDDNAGTAVYTGDVDMQQG
CCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCEECCCCCCCCEEEECCCCCCCC
SMRLTAARVEIERNAQGEVSTVTAHGSGSERAYLEQKPSPDEPVAKGWGDTVIYHAGERR
CEEEEEEEEEEECCCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCH
VELIDRAQLHQGGDTFNGAYVEYFLDRRQVQARSDDDGEGDQRVRMTLTPRNDQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MMTRTLTVALACAALGLASHAALALESDASQPIEIAADQLDLDDNAGTAVYTGDVDMQQG
CCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCEECCCCCCCCEEEECCCCCCCC
SMRLTAARVEIERNAQGEVSTVTAHGSGSERAYLEQKPSPDEPVAKGWGDTVIYHAGERR
CEEEEEEEEEEECCCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCH
VELIDRAQLHQGGDTFNGAYVEYFLDRRQVQARSDDDGEGDQRVRMTLTPRNDQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]