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The map label for this gene is glpD [H]

Identifier: 92114228

GI number: 92114228

Start: 2375043

End: 2376548

Strand: Direct

Name: glpD [H]

Synonym: Csal_2106

Alternate gene names: 92114228

Gene position: 2375043-2376548 (Clockwise)

Preceding gene: 92114227

Following gene: 92114229

Centisome position: 64.25

GC content: 63.08

Gene sequence:

>1506_bases
ATGAACGCCTGCCCCCGACAGGACATACTCGATCTCTTCGTCATCGGCGGTGGCATCAATGGCACCGGTATCGCCAACGA
TGCTGCCGGTCGCGGCCTGCGTGTCGCCCTGAGCGAGCAGCGTGACCTGGCCAGCGCCACCTCGTCGGCGAGCAGCAAGC
TGATCCACGGCGGACTTCGCTATCTCGAACACCGCGAGTTTCGCCTGGTCAGGGAGGCGCTGCACGAACGCGAAGTTCTG
TTGCGCAAGGCGCCGCACATCGTCTGGCCGCTGCGTTTCATCCTGCCGCATCAGCCGCACCTGCGGCCGGCATGGATGAT
TCGTGCGGGCCTGTTTCTCTACGATCACCTTAGCCAGCGCGACAACCTGCCCGCATCACGCAGTCTTCGTTTCGGCGCCG
ACAGCCCGTTGCAACCGAGCATCAAGCGCGGTTTCGAATATTCGGACTGCTGGGTCGACGACGCACGACTGGTGATCCTC
AATGCCATGCAGGCACGCGAAAAAGGCGCCGACATTCAAGTCGGCAGCCGCTGTATCGGCGCAAAGGCAGAAGATGGCAT
CTGGCATATCACGCTGGAAGACGTCACCACCGGCAAACGCCAGACACGCCACGCCAGGGCTCTGGTCAACGCGGCCGGCC
CCTGGGTGGAGAACGTGGTGCGCGAAGGCGTGCAACGCGATTCGCGTTACGGCGTGCGCATGATTCAGGGCAGCCATATC
GTGGTTCCGCGCCTCAATGGCGACGAGCGCGCCTACATTCTTCAGAACCGTGACCGGCGCATCGTCTTCGTTCTACCCTA
TCAGCAAGACTACAGTCTGATCGGCACCACCGACGTACGCTATCAGGGCGACCCCGCCCAGGTCAGCGCCAGCCGACAGG
AGATCGACTATCTCCTCGAGGTGGTCAACCAGCACTTCACGCATCCCCTTACCCACCAGGATGTCATCGCCACCTTTTCC
GGTGTGCGTCCATTGTGCGATGACGAGTCCGCCGACCCGTCGGCGATGACGCGTGATTACACGCTCGATCTCGACGCACG
CGACGCCCCGCTGCTTTCCGTCTTCGGCGGCAAGATCACGACCTATCGCAAACTGGCCGAAGCCGCGCTGGAGCAACTGT
CACCGTACTTCCAGGATATCGGCGAGGCCTGGACCGCCGGCGCCGTCCTGCCGGGGGGCGACATCGATTCGCGTGAAGCC
TTTGCCATGCAACTCGTGCGTGATTACCCATTCCTTGGCGAAGCACGTGCACGACGATTCGCTTCGAGCTATGGCTCGCT
CTGCCTGCGCTTTCTGCACGACACGACCCACGAAGCCCAATTGGGCGATACCTTCGGCGCCGGGCTGACGCAGGCCGAGG
TCGATTATCTGGTCCGCGACGAATGGGCCCGCTCGACAGACGACATCCTCTGGCGGCGCACCAAACTCGGTCTACGCCTC
GACGCTGCGCAGCAGGAGCGGCTGACCACTTATCTCGAGCGTCACCGCCGGGAACACGCCGCCTGA

Upstream 100 bases:

>100_bases
CCCCTTGATGTTCGTTTTCGACTACGCTACTTTCACAATCGAATACTGCAGTCGTCATCGACGATCACCGACCTGCGACA
TCAACCTTGCGGAGCCTGCC

Downstream 100 bases:

>100_bases
GGCGCGACGCAGCAAGAATCTTGGCCCAACGGCCGCCTGGCCTGATACGCTCAAGACTCACGCTACCAGGGACGGTAACG
CACCGCTCGCTATCGGGAGC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MNACPRQDILDLFVIGGGINGTGIANDAAGRGLRVALSEQRDLASATSSASSKLIHGGLRYLEHREFRLVREALHEREVL
LRKAPHIVWPLRFILPHQPHLRPAWMIRAGLFLYDHLSQRDNLPASRSLRFGADSPLQPSIKRGFEYSDCWVDDARLVIL
NAMQAREKGADIQVGSRCIGAKAEDGIWHITLEDVTTGKRQTRHARALVNAAGPWVENVVREGVQRDSRYGVRMIQGSHI
VVPRLNGDERAYILQNRDRRIVFVLPYQQDYSLIGTTDVRYQGDPAQVSASRQEIDYLLEVVNQHFTHPLTHQDVIATFS
GVRPLCDDESADPSAMTRDYTLDLDARDAPLLSVFGGKITTYRKLAEAALEQLSPYFQDIGEAWTAGAVLPGGDIDSREA
FAMQLVRDYPFLGEARARRFASSYGSLCLRFLHDTTHEAQLGDTFGAGLTQAEVDYLVRDEWARSTDDILWRRTKLGLRL
DAAQQERLTTYLERHRREHAA

Sequences:

>Translated_501_residues
MNACPRQDILDLFVIGGGINGTGIANDAAGRGLRVALSEQRDLASATSSASSKLIHGGLRYLEHREFRLVREALHEREVL
LRKAPHIVWPLRFILPHQPHLRPAWMIRAGLFLYDHLSQRDNLPASRSLRFGADSPLQPSIKRGFEYSDCWVDDARLVIL
NAMQAREKGADIQVGSRCIGAKAEDGIWHITLEDVTTGKRQTRHARALVNAAGPWVENVVREGVQRDSRYGVRMIQGSHI
VVPRLNGDERAYILQNRDRRIVFVLPYQQDYSLIGTTDVRYQGDPAQVSASRQEIDYLLEVVNQHFTHPLTHQDVIATFS
GVRPLCDDESADPSAMTRDYTLDLDARDAPLLSVFGGKITTYRKLAEAALEQLSPYFQDIGEAWTAGAVLPGGDIDSREA
FAMQLVRDYPFLGEARARRFASSYGSLCLRFLHDTTHEAQLGDTFGAGLTQAEVDYLVRDEWARSTDDILWRRTKLGLRL
DAAQQERLTTYLERHRREHAA
>Mature_501_residues
MNACPRQDILDLFVIGGGINGTGIANDAAGRGLRVALSEQRDLASATSSASSKLIHGGLRYLEHREFRLVREALHEREVL
LRKAPHIVWPLRFILPHQPHLRPAWMIRAGLFLYDHLSQRDNLPASRSLRFGADSPLQPSIKRGFEYSDCWVDDARLVIL
NAMQAREKGADIQVGSRCIGAKAEDGIWHITLEDVTTGKRQTRHARALVNAAGPWVENVVREGVQRDSRYGVRMIQGSHI
VVPRLNGDERAYILQNRDRRIVFVLPYQQDYSLIGTTDVRYQGDPAQVSASRQEIDYLLEVVNQHFTHPLTHQDVIATFS
GVRPLCDDESADPSAMTRDYTLDLDARDAPLLSVFGGKITTYRKLAEAALEQLSPYFQDIGEAWTAGAVLPGGDIDSREA
FAMQLVRDYPFLGEARARRFASSYGSLCLRFLHDTTHEAQLGDTFGAGLTQAEVDYLVRDEWARSTDDILWRRTKLGLRL
DAAQQERLTTYLERHRREHAA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=526, Percent_Identity=31.3688212927757, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI285002231, Length=526, Percent_Identity=31.3688212927757, Blast_Score=196, Evalue=4e-50,
Organism=Escherichia coli, GI2367226, Length=463, Percent_Identity=58.3153347732181, Blast_Score=553, Evalue=1e-158,
Organism=Escherichia coli, GI1788574, Length=465, Percent_Identity=27.5268817204301, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI115534726, Length=508, Percent_Identity=29.1338582677165, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17509253, Length=534, Percent_Identity=29.4007490636704, Blast_Score=145, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6322036, Length=543, Percent_Identity=27.6243093922652, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI161077125, Length=520, Percent_Identity=29.8076923076923, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24653942, Length=520, Percent_Identity=29.8076923076923, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24653944, Length=520, Percent_Identity=29.8076923076923, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI20130025, Length=520, Percent_Identity=29.8076923076923, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24586295, Length=506, Percent_Identity=29.4466403162055, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI19921278, Length=492, Percent_Identity=23.5772357723577, Blast_Score=93, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56428; Mature: 56428

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNACPRQDILDLFVIGGGINGTGIANDAAGRGLRVALSEQRDLASATSSASSKLIHGGLR
CCCCCCHHHHEEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
YLEHREFRLVREALHEREVLLRKAPHIVWPLRFILPHQPHLRPAWMIRAGLFLYDHLSQR
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
DNLPASRSLRFGADSPLQPSIKRGFEYSDCWVDDARLVILNAMQAREKGADIQVGSRCIG
CCCCCCCCEECCCCCCCCHHHHCCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEECCEEEC
AKAEDGIWHITLEDVTTGKRQTRHARALVNAAGPWVENVVREGVQRDSRYGVRMIQGSHI
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCEE
VVPRLNGDERAYILQNRDRRIVFVLPYQQDYSLIGTTDVRYQGDPAQVSASRQEIDYLLE
EEECCCCCCEEEEEECCCCEEEEEEECCCCCCEEECCCEEECCCHHHHHHHHHHHHHHHH
VVNQHFTHPLTHQDVIATFSGVRPLCDDESADPSAMTRDYTLDLDARDAPLLSVFGGKIT
HHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHCCCHH
TYRKLAEAALEQLSPYFQDIGEAWTAGAVLPGGDIDSREAFAMQLVRDYPFLGEARARRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
ASSYGSLCLRFLHDTTHEAQLGDTFGAGLTQAEVDYLVRDEWARSTDDILWRRTKLGLRL
HHHHHHHHHHHHHCCCCHHHCCCHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCEEE
DAAQQERLTTYLERHRREHAA
CHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNACPRQDILDLFVIGGGINGTGIANDAAGRGLRVALSEQRDLASATSSASSKLIHGGLR
CCCCCCHHHHEEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
YLEHREFRLVREALHEREVLLRKAPHIVWPLRFILPHQPHLRPAWMIRAGLFLYDHLSQR
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
DNLPASRSLRFGADSPLQPSIKRGFEYSDCWVDDARLVILNAMQAREKGADIQVGSRCIG
CCCCCCCCEECCCCCCCCHHHHCCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEECCEEEC
AKAEDGIWHITLEDVTTGKRQTRHARALVNAAGPWVENVVREGVQRDSRYGVRMIQGSHI
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCEE
VVPRLNGDERAYILQNRDRRIVFVLPYQQDYSLIGTTDVRYQGDPAQVSASRQEIDYLLE
EEECCCCCCEEEEEECCCCEEEEEEECCCCCCEEECCCEEECCCHHHHHHHHHHHHHHHH
VVNQHFTHPLTHQDVIATFSGVRPLCDDESADPSAMTRDYTLDLDARDAPLLSVFGGKIT
HHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHCCCHH
TYRKLAEAALEQLSPYFQDIGEAWTAGAVLPGGDIDSREAFAMQLVRDYPFLGEARARRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
ASSYGSLCLRFLHDTTHEAQLGDTFGAGLTQAEVDYLVRDEWARSTDDILWRRTKLGLRL
HHHHHHHHHHHHHCCCCHHHCCCHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCEEE
DAAQQERLTTYLERHRREHAA
CHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]