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The map label for this gene is ppnK

Identifier: 92113433

GI number: 92113433

Start: 1491050

End: 1491931

Strand: Direct

Name: ppnK

Synonym: Csal_1307

Alternate gene names: 92113433

Gene position: 1491050-1491931 (Clockwise)

Preceding gene: 92113432

Following gene: 92113434

Centisome position: 40.34

GC content: 64.74

Gene sequence:

>882_bases
ATGCAGCCATTCAAGACCATTGGCCTGATCGGGCGATTGGGCAGCCCCAATGCAGTGGAGACGCTCAAGCGGTTGCTGCG
CTTCCTCGGCACCCGTGAGCTCGATGTGATCGTCGACGAACGCACCGCCACGGTGCTGCTCAACCACGGCTACCCCGAGG
CGAGCCGCAGTCGCCTGGGGGAGCTTTGCGACCTGGTGATCGTGGTGGGGGGCGACGGCAGCCTGCTCAGCGCGGCACGC
GTGCTGTGCCAGACCCAGACGCCGGTGCTGGGGGTCAATCGCGGGCGCCTGGGGTTTCTCACCGATATTTCTCCGGACGA
CGTCGAGGAGCGGATCGGCGAGGTGCTCGACGGCCATTTCGAGAGCGAGCAGCGCTTTCTGCTCGAAGCGGAAGTCTTTC
GCGCCGGCAAGCAGGTGGGCACAGCCTCGGGGCTCAACGACGTGGTCATCCACCCCGGCAAGGCGGCGCGCATGATCGAG
TTCGAACTGTTCATCGATGGGCAGTTCGTCTATAGCCAGCGCAGCGATGGGTTGATCATCGCCACGCCAACCGGCTCCAC
CGCCTATGCCTTGTCGGGGGGCGGACCCATCGTGCACCCGCGCCTCGAGGCCATCACCCTGGTGCCGATGTTCCCTCATA
CTCTCTCCAGCCGGCCGATCGTCGTCGATGCCGCCAGCGAGGTCACGATTCACATCGGCGAGACCAATCAGGCGTATCCC
CACGTCAGTTGCGATGGCCAGACCCAGGTGGTGTCCAAACCCGGCGACATCATGGTCGTGCGTCGCAAGCGCGAACGCCT
GACCCTGATTCACCCACGCGGACACAACTACTTCGAGACCTGTCGCACCAAGCTCGGCTGGAGCAGCCGGTTGGGAGAGT
GA

Upstream 100 bases:

>100_bases
GCATGCCGCCGGCCGGCGGCGTCGCGGGTGCTCGCGGTTTGCTCCCCCGAGCGCCAGTCCGCATAATGACGGGCCGCGAT
GCCGGCAACGAGACGTTTTC

Downstream 100 bases:

>100_bases
CATGACATTGCCTCGCCACGACCTCGATGGCTACGACTTGATCGGCGATGTCCACGGCTGTGGCGCATCGCTGGCCGTGC
TGCTGGAGAAGCTCGGCTAT

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MQPFKTIGLIGRLGSPNAVETLKRLLRFLGTRELDVIVDERTATVLLNHGYPEASRSRLGELCDLVIVVGGDGSLLSAAR
VLCQTQTPVLGVNRGRLGFLTDISPDDVEERIGEVLDGHFESEQRFLLEAEVFRAGKQVGTASGLNDVVIHPGKAARMIE
FELFIDGQFVYSQRSDGLIIATPTGSTAYALSGGGPIVHPRLEAITLVPMFPHTLSSRPIVVDAASEVTIHIGETNQAYP
HVSCDGQTQVVSKPGDIMVVRRKRERLTLIHPRGHNYFETCRTKLGWSSRLGE

Sequences:

>Translated_293_residues
MQPFKTIGLIGRLGSPNAVETLKRLLRFLGTRELDVIVDERTATVLLNHGYPEASRSRLGELCDLVIVVGGDGSLLSAAR
VLCQTQTPVLGVNRGRLGFLTDISPDDVEERIGEVLDGHFESEQRFLLEAEVFRAGKQVGTASGLNDVVIHPGKAARMIE
FELFIDGQFVYSQRSDGLIIATPTGSTAYALSGGGPIVHPRLEAITLVPMFPHTLSSRPIVVDAASEVTIHIGETNQAYP
HVSCDGQTQVVSKPGDIMVVRRKRERLTLIHPRGHNYFETCRTKLGWSSRLGE
>Mature_293_residues
MQPFKTIGLIGRLGSPNAVETLKRLLRFLGTRELDVIVDERTATVLLNHGYPEASRSRLGELCDLVIVVGGDGSLLSAAR
VLCQTQTPVLGVNRGRLGFLTDISPDDVEERIGEVLDGHFESEQRFLLEAEVFRAGKQVGTASGLNDVVIHPGKAARMIE
FELFIDGQFVYSQRSDGLIIATPTGSTAYALSGGGPIVHPRLEAITLVPMFPHTLSSRPIVVDAASEVTIHIGETNQAYP
HVSCDGQTQVVSKPGDIMVVRRKRERLTLIHPRGHNYFETCRTKLGWSSRLGE

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Homo sapiens, GI55743112, Length=255, Percent_Identity=30.5882352941176, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI1788968, Length=288, Percent_Identity=48.2638888888889, Blast_Score=290, Evalue=8e-80,
Organism=Saccharomyces cerevisiae, GI6320794, Length=242, Percent_Identity=31.404958677686, Blast_Score=135, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6322509, Length=242, Percent_Identity=29.3388429752066, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325068, Length=204, Percent_Identity=33.8235294117647, Blast_Score=116, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573828, Length=255, Percent_Identity=34.1176470588235, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28573826, Length=255, Percent_Identity=34.1176470588235, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28573830, Length=255, Percent_Identity=34.1176470588235, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28573832, Length=255, Percent_Identity=34.1176470588235, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI161077047, Length=255, Percent_Identity=34.1176470588235, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24653422, Length=286, Percent_Identity=30.4195804195804, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI20129957, Length=286, Percent_Identity=30.4195804195804, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI281363321, Length=286, Percent_Identity=30.4195804195804, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24653424, Length=286, Percent_Identity=30.4195804195804, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281363323, Length=286, Percent_Identity=30.4195804195804, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_CHRSD (Q1QXZ6)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_573361.1
- ProteinModelPortal:   Q1QXZ6
- SMR:   Q1QXZ6
- STRING:   Q1QXZ6
- GeneID:   4027761
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_1307
- NMPDR:   fig|290398.4.peg.1297
- eggNOG:   COG0061
- HOGENOM:   HBG713904
- OMA:   FESFMID
- ProtClustDB:   PRK01231
- BioCyc:   CSAL290398:CSAL_1307-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 32004; Mature: 32004

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPFKTIGLIGRLGSPNAVETLKRLLRFLGTRELDVIVDERTATVLLNHGYPEASRSRLG
CCCHHHHHHEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCHHHHHHHH
ELCDLVIVVGGDGSLLSAARVLCQTQTPVLGVNRGRLGFLTDISPDDVEERIGEVLDGHF
HHEEEEEEECCCCCHHHHHHHHHCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHCCCC
ESEQRFLLEAEVFRAGKQVGTASGLNDVVIHPGKAARMIEFELFIDGQFVYSQRSDGLII
CCCHHHHHHHHHHHCCHHCCCCCCCCCEEECCCCCCEEEEEEEEECCEEEEECCCCCEEE
ATPTGSTAYALSGGGPIVHPRLEAITLVPMFPHTLSSRPIVVDAASEVTIHIGETNQAYP
EECCCCEEEEECCCCCEECCCEEEEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCCC
HVSCDGQTQVVSKPGDIMVVRRKRERLTLIHPRGHNYFETCRTKLGWSSRLGE
EECCCCCEEEECCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MQPFKTIGLIGRLGSPNAVETLKRLLRFLGTRELDVIVDERTATVLLNHGYPEASRSRLG
CCCHHHHHHEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCHHHHHHHH
ELCDLVIVVGGDGSLLSAARVLCQTQTPVLGVNRGRLGFLTDISPDDVEERIGEVLDGHF
HHEEEEEEECCCCCHHHHHHHHHCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHCCCC
ESEQRFLLEAEVFRAGKQVGTASGLNDVVIHPGKAARMIEFELFIDGQFVYSQRSDGLII
CCCHHHHHHHHHHHCCHHCCCCCCCCCEEECCCCCCEEEEEEEEECCEEEEECCCCCEEE
ATPTGSTAYALSGGGPIVHPRLEAITLVPMFPHTLSSRPIVVDAASEVTIHIGETNQAYP
EECCCCEEEEECCCCCEECCCEEEEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCCC
HVSCDGQTQVVSKPGDIMVVRRKRERLTLIHPRGHNYFETCRTKLGWSSRLGE
EECCCCCEEEECCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA