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The map label for this gene is sucD [H]

Identifier: 92113347

GI number: 92113347

Start: 1399397

End: 1400269

Strand: Direct

Name: sucD [H]

Synonym: Csal_1221

Alternate gene names: 92113347

Gene position: 1399397-1400269 (Clockwise)

Preceding gene: 92113346

Following gene: 92113353

Centisome position: 37.86

GC content: 63.69

Gene sequence:

>873_bases
ATGAGTATCCTGATCGACAAGAGCACCAAGGTCATCTGCCAAGGTTTCACGGGTGGCCAGGGGACTTTCCACTCCGAGCA
GGCGATCGCCTACGGTACCCAGATGGTCGGTGGCGTGACGCCGGGCAAGGGCGGCCAGACGCACCTCGGCCTGCCGGTGT
TCAACACCGTCAAGGAAGCCGTCGAAACGACGGGTGCCGAAGCGTCCGTGATCTACGTGCCCGCGCCGTTCTGCAAGGAT
TCCATCCTGGAAGCGGCCAATGCCGGCATCAAGCTGATCGTGTGCATCACCGAGGGGATTCCCACCCTCGACATGCTCGA
CGTCAAGGTCAAGTGCGACGAGCTGGGTGTGCGCCTGATCGGGCCGAACTGCCCGGGCGTGATCACGCCGGGCGAGACCA
AGATCGGCATCATGCCGGGTCACATTCACAAGCCGGGCAAGGTCGGTATCGTCTCGCGTTCGGGCACCTTGACCTATGAA
GCGGTCAAGCAGACCACCGATCACGGCTTCGGCCAGTCCACCTGCGTGGGCATCGGCGGCGATCCGATCCCGGGCTCCAC
CTTCATCGACATGCTCGAGATGTTCGAGAAGGACCCGCAGACCGAAGCCATCGTGATGATCGGCGAAATCGGCGGCACGG
CGGAAGAAGAAGCCGCGGCATACATCAAGGAGCACGTCTCCAAGCCGGTGGTATCCTATATCGCCGGTGTGACGGCGCCT
CCGGGCAAGCGCATGGGCCACGCGGGTGCCATCATCGCCGGTGGCAAGGGCACGGCCGACGAGAAGTTCGCCGCGCTCGA
GTCTGCAGGTGTCAAGACCGTGCGTTCGCTCGCCGAGATCGGCGATGCGCTGAAGGCAGCCACGGGCTGGTAA

Upstream 100 bases:

>100_bases
TGGGCGCCGAGAAACTGGCATCCAGTGGACTGAACATCATCGCTGCTACCAGCTTGACCGACGCGGCCCAGCAGGTCGTC
AAAGCAGCGGAGGGCAAGTA

Downstream 100 bases:

>100_bases
GTCGCTGGCGTGATCGTCGGCGGTGACATGCCGCCGAATCACCCGCACGTTGAAGGCATCCCTCCGGGGATGCCTTCTTG
CGTTTGGGGGCTGACAATTT

Product: succinyl-CoA synthetase (ADP-forming) alpha subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSILIDKSTKVICQGFTGGQGTFHSEQAIAYGTQMVGGVTPGKGGQTHLGLPVFNTVKEAVETTGAEASVIYVPAPFCKD
SILEAANAGIKLIVCITEGIPTLDMLDVKVKCDELGVRLIGPNCPGVITPGETKIGIMPGHIHKPGKVGIVSRSGTLTYE
AVKQTTDHGFGQSTCVGIGGDPIPGSTFIDMLEMFEKDPQTEAIVMIGEIGGTAEEEAAAYIKEHVSKPVVSYIAGVTAP
PGKRMGHAGAIIAGGKGTADEKFAALESAGVKTVRSLAEIGDALKAATGW

Sequences:

>Translated_290_residues
MSILIDKSTKVICQGFTGGQGTFHSEQAIAYGTQMVGGVTPGKGGQTHLGLPVFNTVKEAVETTGAEASVIYVPAPFCKD
SILEAANAGIKLIVCITEGIPTLDMLDVKVKCDELGVRLIGPNCPGVITPGETKIGIMPGHIHKPGKVGIVSRSGTLTYE
AVKQTTDHGFGQSTCVGIGGDPIPGSTFIDMLEMFEKDPQTEAIVMIGEIGGTAEEEAAAYIKEHVSKPVVSYIAGVTAP
PGKRMGHAGAIIAGGKGTADEKFAALESAGVKTVRSLAEIGDALKAATGW
>Mature_289_residues
SILIDKSTKVICQGFTGGQGTFHSEQAIAYGTQMVGGVTPGKGGQTHLGLPVFNTVKEAVETTGAEASVIYVPAPFCKDS
ILEAANAGIKLIVCITEGIPTLDMLDVKVKCDELGVRLIGPNCPGVITPGETKIGIMPGHIHKPGKVGIVSRSGTLTYEA
VKQTTDHGFGQSTCVGIGGDPIPGSTFIDMLEMFEKDPQTEAIVMIGEIGGTAEEEAAAYIKEHVSKPVVSYIAGVTAPP
GKRMGHAGAIIAGGKGTADEKFAALESAGVKTVRSLAEIGDALKAATGW

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=68.6411149825784, Blast_Score=334, Evalue=6e-92,
Organism=Homo sapiens, GI38569423, Length=259, Percent_Identity=35.1351351351351, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI38569421, Length=259, Percent_Identity=35.1351351351351, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1786949, Length=285, Percent_Identity=90.1754385964912, Blast_Score=513, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17550194, Length=291, Percent_Identity=62.1993127147766, Blast_Score=334, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17553126, Length=291, Percent_Identity=62.1993127147766, Blast_Score=332, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17557344, Length=255, Percent_Identity=30.5882352941176, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17551266, Length=255, Percent_Identity=30.5882352941176, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=52.7397260273973, Blast_Score=276, Evalue=3e-75,
Organism=Drosophila melanogaster, GI21356559, Length=289, Percent_Identity=58.1314878892734, Blast_Score=325, Evalue=2e-89,
Organism=Drosophila melanogaster, GI28574296, Length=288, Percent_Identity=61.8055555555556, Blast_Score=322, Evalue=2e-88,
Organism=Drosophila melanogaster, GI281363477, Length=259, Percent_Identity=30.1158301158301, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281363475, Length=259, Percent_Identity=30.1158301158301, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281363473, Length=259, Percent_Identity=30.1158301158301, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29849; Mature: 29718

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILIDKSTKVICQGFTGGQGTFHSEQAIAYGTQMVGGVTPGKGGQTHLGLPVFNTVKEA
CEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHH
VETTGAEASVIYVPAPFCKDSILEAANAGIKLIVCITEGIPTLDMLDVKVKCDELGVRLI
HHHCCCCEEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCCEEEEEEEEEHHHCCEEEE
GPNCPGVITPGETKIGIMPGHIHKPGKVGIVSRSGTLTYEAVKQTTDHGFGQSTCVGIGG
CCCCCCEECCCCCEEEEECCCCCCCCCEEEEECCCCEEHHHHHHHHCCCCCCCEEEECCC
DPIPGSTFIDMLEMFEKDPQTEAIVMIGEIGGTAEEEAAAYIKEHVSKPVVSYIAGVTAP
CCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PGKRMGHAGAIIAGGKGTADEKFAALESAGVKTVRSLAEIGDALKAATGW
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SILIDKSTKVICQGFTGGQGTFHSEQAIAYGTQMVGGVTPGKGGQTHLGLPVFNTVKEA
EEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHH
VETTGAEASVIYVPAPFCKDSILEAANAGIKLIVCITEGIPTLDMLDVKVKCDELGVRLI
HHHCCCCEEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCCEEEEEEEEEHHHCCEEEE
GPNCPGVITPGETKIGIMPGHIHKPGKVGIVSRSGTLTYEAVKQTTDHGFGQSTCVGIGG
CCCCCCEECCCCCEEEEECCCCCCCCCEEEEECCCCEEHHHHHHHHCCCCCCCEEEECCC
DPIPGSTFIDMLEMFEKDPQTEAIVMIGEIGGTAEEEAAAYIKEHVSKPVVSYIAGVTAP
CCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PGKRMGHAGAIIAGGKGTADEKFAALESAGVKTVRSLAEIGDALKAATGW
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]