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The map label for this gene is sucC [H]

Identifier: 92113346

GI number: 92113346

Start: 1398168

End: 1399397

Strand: Direct

Name: sucC [H]

Synonym: Csal_1220

Alternate gene names: 92113346

Gene position: 1398168-1399397 (Clockwise)

Preceding gene: 92113345

Following gene: 92113347

Centisome position: 37.82

GC content: 62.03

Gene sequence:

>1230_bases
GTGACGGCGACCTCGTGGGTGGCCGCCACCATTCGAGTCACATGCAACCAATGGCATGACACGATGAACCTTCACGAGTA
TCAGAGCAAACAGCTGTTTGCCGATTATGGTCTACCGGTGTCCAAGGGTTTCGCCGTGGATACCCCCGAAGAAGCCGCCG
AAGCGTGCAAGAAGATCGGTGGTGACAAGTGGGTCGTCAAGGCCCAGGTTCACGCGGGCGGCCGCGGCAAGGCCGGCGGC
GTCAAGCTGGTCGAAAGCCCCGCCGACGCCAAGGCCTTCGCCGAGCAGTGGCTGGGCAAGAACCTGGTGACCTTCCAGAC
TGACGAGAAGGGTCAGCCGGTCGCCAAGATCCTGGTCGAGAACTGCACCGACATCGCCAACGAGCTGTACCTGGGCGCCG
TCGTCGACCGTGGCACCCGCCGCATCGTTTTCATGGCTTCCACCGAAGGTGGCGTGGAAATCGAGAAGGTTGCCGAGGAA
ACTCCCGAGAAGATTCTCAAGGCCGAGATCGATCCCCTGGTCGGCGCTCAGCCGTATCAGGCGCGTGAGCTGGCCTTCGC
GCTGGGTCTCGAAGGCGCGCAGATCAAGCAGTTCACCAAGATCTTCCTGGGGCTGGCCAAGCTGTTCCAGGAAAAGGATC
TGGCGCTGCTCGAGATCAATCCGCTGGTGATCACCGACGAAGGCAATCTGCATTGCCTCGACGCCAAGATCGGTCTGGAC
GGCAATGCCCTGTATCGCCACCCCGATCTGCAGGCGATGCGTGACCCGTCTCAGGAAGACGAGCGCGAAGCGCATGCTCA
GGAGTGGGAACTCAACTACGTCGCCCTGGAAGGCAACATCGGCTGCATGGTCAACGGTGCCGGCCTGGCCATGGGCACCA
TGGACATCATCAAGCTCAACGGCGGCCAGCCGGCCAACTTCCTTGACGTTGGCGGCGGTGCGACGGAAGAGCGCGTCGGC
GAGGCGTTCAAGATCATCCTGTCCGACGATTCCGTGAAGGCCGTCCTGGTCAACATCTTCGGCGGCATCGTCCGTTGCGA
CATGATCGCCGAAGGCATCATCGGTGCCGTCGAGCAGGTCGGTGTCAACGTGCCGGTCGTGGTGCGTCTCGAGGGCAACA
ACGCCGAGCTGGGCGCCGAGAAACTGGCATCCAGTGGACTGAACATCATCGCTGCTACCAGCTTGACCGACGCGGCCCAG
CAGGTCGTCAAAGCAGCGGAGGGCAAGTAA

Upstream 100 bases:

>100_bases
CGCCATTCACATGGCCAACCGCAAGAAGCGCAAGTAAGCGTTTCGATCTGCGTTTCAGTGTAGAGACGCGTCGCTCCCGC
CTCGGCGGGAGCGAACAGGG

Downstream 100 bases:

>100_bases
TGAGTATCCTGATCGACAAGAGCACCAAGGTCATCTGCCAAGGTTTCACGGGTGGCCAGGGGACTTTCCACTCCGAGCAG
GCGATCGCCTACGGTACCCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTATSWVAATIRVTCNQWHDTMNLHEYQSKQLFADYGLPVSKGFAVDTPEEAAEACKKIGGDKWVVKAQVHAGGRGKAGG
VKLVESPADAKAFAEQWLGKNLVTFQTDEKGQPVAKILVENCTDIANELYLGAVVDRGTRRIVFMASTEGGVEIEKVAEE
TPEKILKAEIDPLVGAQPYQARELAFALGLEGAQIKQFTKIFLGLAKLFQEKDLALLEINPLVITDEGNLHCLDAKIGLD
GNALYRHPDLQAMRDPSQEDEREAHAQEWELNYVALEGNIGCMVNGAGLAMGTMDIIKLNGGQPANFLDVGGGATEERVG
EAFKIILSDDSVKAVLVNIFGGIVRCDMIAEGIIGAVEQVGVNVPVVVRLEGNNAELGAEKLASSGLNIIAATSLTDAAQ
QVVKAAEGK

Sequences:

>Translated_409_residues
MTATSWVAATIRVTCNQWHDTMNLHEYQSKQLFADYGLPVSKGFAVDTPEEAAEACKKIGGDKWVVKAQVHAGGRGKAGG
VKLVESPADAKAFAEQWLGKNLVTFQTDEKGQPVAKILVENCTDIANELYLGAVVDRGTRRIVFMASTEGGVEIEKVAEE
TPEKILKAEIDPLVGAQPYQARELAFALGLEGAQIKQFTKIFLGLAKLFQEKDLALLEINPLVITDEGNLHCLDAKIGLD
GNALYRHPDLQAMRDPSQEDEREAHAQEWELNYVALEGNIGCMVNGAGLAMGTMDIIKLNGGQPANFLDVGGGATEERVG
EAFKIILSDDSVKAVLVNIFGGIVRCDMIAEGIIGAVEQVGVNVPVVVRLEGNNAELGAEKLASSGLNIIAATSLTDAAQ
QVVKAAEGK
>Mature_408_residues
TATSWVAATIRVTCNQWHDTMNLHEYQSKQLFADYGLPVSKGFAVDTPEEAAEACKKIGGDKWVVKAQVHAGGRGKAGGV
KLVESPADAKAFAEQWLGKNLVTFQTDEKGQPVAKILVENCTDIANELYLGAVVDRGTRRIVFMASTEGGVEIEKVAEET
PEKILKAEIDPLVGAQPYQARELAFALGLEGAQIKQFTKIFLGLAKLFQEKDLALLEINPLVITDEGNLHCLDAKIGLDG
NALYRHPDLQAMRDPSQEDEREAHAQEWELNYVALEGNIGCMVNGAGLAMGTMDIIKLNGGQPANFLDVGGGATEERVGE
AFKIILSDDSVKAVLVNIFGGIVRCDMIAEGIIGAVEQVGVNVPVVVRLEGNNAELGAEKLASSGLNIIAATSLTDAAQQ
VVKAAEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=394, Percent_Identity=46.9543147208122, Blast_Score=342, Evalue=3e-94,
Organism=Homo sapiens, GI157779135, Length=394, Percent_Identity=44.6700507614213, Blast_Score=318, Evalue=4e-87,
Organism=Homo sapiens, GI294862256, Length=373, Percent_Identity=45.0402144772118, Blast_Score=306, Evalue=2e-83,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=77.0618556701031, Blast_Score=584, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI17567829, Length=392, Percent_Identity=44.8979591836735, Blast_Score=320, Evalue=8e-88,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=43.2569974554707, Blast_Score=309, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6321683, Length=398, Percent_Identity=44.4723618090452, Blast_Score=340, Evalue=2e-94,
Organism=Drosophila melanogaster, GI21356231, Length=392, Percent_Identity=44.1326530612245, Blast_Score=308, Evalue=3e-84,
Organism=Drosophila melanogaster, GI161078106, Length=398, Percent_Identity=43.7185929648241, Blast_Score=301, Evalue=6e-82,
Organism=Drosophila melanogaster, GI24645208, Length=398, Percent_Identity=43.7185929648241, Blast_Score=301, Evalue=6e-82,
Organism=Drosophila melanogaster, GI281361397, Length=399, Percent_Identity=43.859649122807, Blast_Score=299, Evalue=3e-81,
Organism=Drosophila melanogaster, GI281361395, Length=399, Percent_Identity=43.859649122807, Blast_Score=299, Evalue=3e-81,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 43723; Mature: 43592

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATSWVAATIRVTCNQWHDTMNLHEYQSKQLFADYGLPVSKGFAVDTPEEAAEACKKIG
CCCCCEEEEEEEEEEHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
GDKWVVKAQVHAGGRGKAGGVKLVESPADAKAFAEQWLGKNLVTFQTDEKGQPVAKILVE
CCEEEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
NCTDIANELYLGAVVDRGTRRIVFMASTEGGVEIEKVAEETPEKILKAEIDPLVGAQPYQ
HHHHHHHHHEEHHEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCH
ARELAFALGLEGAQIKQFTKIFLGLAKLFQEKDLALLEINPLVITDEGNLHCLDAKIGLD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEECCCCEEEEEEEECCC
GNALYRHPDLQAMRDPSQEDEREAHAQEWELNYVALEGNIGCMVNGAGLAMGTMDIIKLN
CCEEEECCCHHHHCCCCCHHHHHHHHHHEEEEEEEEECCCEEEEECCCEEECCEEEEEEC
GGQPANFLDVGGGATEERVGEAFKIILSDDSVKAVLVNIFGGIVRCDMIAEGIIGAVEQV
CCCCCCEEECCCCCCHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVNVPVVVRLEGNNAELGAEKLASSGLNIIAATSLTDAAQQVVKAAEGK
CCCCCEEEEECCCCCCCCHHHHHHCCCCEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TATSWVAATIRVTCNQWHDTMNLHEYQSKQLFADYGLPVSKGFAVDTPEEAAEACKKIG
CCCCEEEEEEEEEEHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
GDKWVVKAQVHAGGRGKAGGVKLVESPADAKAFAEQWLGKNLVTFQTDEKGQPVAKILVE
CCEEEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
NCTDIANELYLGAVVDRGTRRIVFMASTEGGVEIEKVAEETPEKILKAEIDPLVGAQPYQ
HHHHHHHHHEEHHEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCH
ARELAFALGLEGAQIKQFTKIFLGLAKLFQEKDLALLEINPLVITDEGNLHCLDAKIGLD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEECCCCEEEEEEEECCC
GNALYRHPDLQAMRDPSQEDEREAHAQEWELNYVALEGNIGCMVNGAGLAMGTMDIIKLN
CCEEEECCCHHHHCCCCCHHHHHHHHHHEEEEEEEEECCCEEEEECCCEEECCEEEEEEC
GGQPANFLDVGGGATEERVGEAFKIILSDDSVKAVLVNIFGGIVRCDMIAEGIIGAVEQV
CCCCCCEEECCCCCCHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVNVPVVVRLEGNNAELGAEKLASSGLNIIAATSLTDAAQQVVKAAEGK
CCCCCEEEEECCCCCCCCHHHHHHCCCCEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA