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The map label for this gene is ribD [H]

Identifier: 92113300

GI number: 92113300

Start: 1346331

End: 1347182

Strand: Direct

Name: ribD [H]

Synonym: Csal_1173

Alternate gene names: 92113300

Gene position: 1346331-1347182 (Clockwise)

Preceding gene: 92113298

Following gene: 92113306

Centisome position: 36.42

GC content: 69.01

Gene sequence:

>852_bases
ATGAGCGCTTCGATACTCGATGCAGCGTTGGCCTGGCAATGGATCGGCCAGATTCGCGAACAGGACTGGCATGCCCAGGC
CACGCTGACGCTGCGCTCGCCAGCGTGTACCTTGCGGGTTCAACGCGGCGGTGACTGGCAGGCCGAGGGCGAGGTGACGG
CGGACGCCGCGGCGCTGCTCGATACCTTGCTGCCCTGCTGTGCCACGCCGGGGCGTTTCGTCATCGGCCAGCTCGGGCAG
AGCCTCGATGGGCGCATCGCCACGGTCAGCGGTGCGTCGCATTACGTCACCGGCGAGGCGAGTCGCGTGCATCTGCACCG
GCTGCGCGCGCTGGTCGATGCCGTCCTGATCGGCGCGGGGACGGCATGCGCCGACGACCCACGGCTCAGCGTGCGGCACG
TGTCGGGACATAACCCGGTTCGCGTGATTCTCGATCCCAATGGGCGCGTGCCCGCCACCCAGGGCGTGTTCCAGAACGAC
GAGGCGCCGACCTTGCACATCACGCGGCATCCGTTGCCTCGGGGAGCGCTGGGGGCGCATGTCGATACCTGTGTGGTCGA
AGATGCCGCCGACCTGACGCCGGCTGCCTTGTGCAGGACCCTGGCAGCACGCGGCTTGCGGCGTGTGCTGGTCGAAGGCG
GCGGGCAGACCGTGTCGCGCTTCTTGGCCGACGGCGAGCTCGATCGCCTGCATGTCGTGGTGGCGCCGCTGTTGATCGGC
TCGGGGCGTCCGGCGGTGAGTCTCGCCGAGATCGAGACGCTCGACACCGCCCTGCGACCACCGTGCCGCACGTTCGCGAT
GGGAGACGATACCTTGTTCGATCTGGCGCTGCGTGCCGTCGACGCGGCGTGA

Upstream 100 bases:

>100_bases
GCTTCGATGACGTCTGGTCCGCCTGCGGCGCCTCGTCTCGCGACGTGGCCAGACGGCAGGCGGGATGGCGTTTTCGCCGG
CACACGGCATGGGAGACCGT

Downstream 100 bases:

>100_bases
TACGTCATCGTGCATGGCGGTCTCCTCAGCGTTCGCTCGTCAGCGGGGCGCCCGGCGGCGGGGTGTCGCGGCCCTGGCGT
GGCGGACGCCGACGGCACAG

Product: bifunctional deaminase-reductase-like protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSASILDAALAWQWIGQIREQDWHAQATLTLRSPACTLRVQRGGDWQAEGEVTADAAALLDTLLPCCATPGRFVIGQLGQ
SLDGRIATVSGASHYVTGEASRVHLHRLRALVDAVLIGAGTACADDPRLSVRHVSGHNPVRVILDPNGRVPATQGVFQND
EAPTLHITRHPLPRGALGAHVDTCVVEDAADLTPAALCRTLAARGLRRVLVEGGGQTVSRFLADGELDRLHVVVAPLLIG
SGRPAVSLAEIETLDTALRPPCRTFAMGDDTLFDLALRAVDAA

Sequences:

>Translated_283_residues
MSASILDAALAWQWIGQIREQDWHAQATLTLRSPACTLRVQRGGDWQAEGEVTADAAALLDTLLPCCATPGRFVIGQLGQ
SLDGRIATVSGASHYVTGEASRVHLHRLRALVDAVLIGAGTACADDPRLSVRHVSGHNPVRVILDPNGRVPATQGVFQND
EAPTLHITRHPLPRGALGAHVDTCVVEDAADLTPAALCRTLAARGLRRVLVEGGGQTVSRFLADGELDRLHVVVAPLLIG
SGRPAVSLAEIETLDTALRPPCRTFAMGDDTLFDLALRAVDAA
>Mature_282_residues
SASILDAALAWQWIGQIREQDWHAQATLTLRSPACTLRVQRGGDWQAEGEVTADAAALLDTLLPCCATPGRFVIGQLGQS
LDGRIATVSGASHYVTGEASRVHLHRLRALVDAVLIGAGTACADDPRLSVRHVSGHNPVRVILDPNGRVPATQGVFQNDE
APTLHITRHPLPRGALGAHVDTCVVEDAADLTPAALCRTLAARGLRRVLVEGGGQTVSRFLADGELDRLHVVVAPLLIGS
GRPAVSLAEIETLDTALRPPCRTFAMGDDTLFDLALRAVDAA

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=235, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 29930; Mature: 29799

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASILDAALAWQWIGQIREQDWHAQATLTLRSPACTLRVQRGGDWQAEGEVTADAAALL
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHH
DTLLPCCATPGRFVIGQLGQSLDGRIATVSGASHYVTGEASRVHLHRLRALVDAVLIGAG
HHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHCCC
TACADDPRLSVRHVSGHNPVRVILDPNGRVPATQGVFQNDEAPTLHITRHPLPRGALGAH
CCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCC
VDTCVVEDAADLTPAALCRTLAARGLRRVLVEGGGQTVSRFLADGELDRLHVVVAPLLIG
HHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHEEEHHHCC
SGRPAVSLAEIETLDTALRPPCRTFAMGDDTLFDLALRAVDAA
CCCCCEEHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SASILDAALAWQWIGQIREQDWHAQATLTLRSPACTLRVQRGGDWQAEGEVTADAAALL
CCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHH
DTLLPCCATPGRFVIGQLGQSLDGRIATVSGASHYVTGEASRVHLHRLRALVDAVLIGAG
HHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHCCC
TACADDPRLSVRHVSGHNPVRVILDPNGRVPATQGVFQNDEAPTLHITRHPLPRGALGAH
CCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCC
VDTCVVEDAADLTPAALCRTLAARGLRRVLVEGGGQTVSRFLADGELDRLHVVVAPLLIG
HHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHEEEHHHCC
SGRPAVSLAEIETLDTALRPPCRTFAMGDDTLFDLALRAVDAA
CCCCCEEHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]