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The map label for this gene is rpfC [H]

Identifier: 92113190

GI number: 92113190

Start: 1200562

End: 1202649

Strand: Direct

Name: rpfC [H]

Synonym: Csal_1062

Alternate gene names: 92113190

Gene position: 1200562-1202649 (Clockwise)

Preceding gene: 92113189

Following gene: 92113195

Centisome position: 32.48

GC content: 59.77

Gene sequence:

>2088_bases
ATGGCGCTGGAGCAGGTGGAAAGCCGGCCGACACACGGCGTATCAGGTACTCGTGGCGAGCTTTCTTCCTGGACCCGGCT
GATGGAGCGTTTTGACATTCTCTACGGCAGGATAAAGCTGCTGCAGCAAGGACAATATCGCCAATATCTGGCATCACAGC
CTGAGCTCCTTGAAGCATTGTGGCACCTCGATGCTCGTCTTGAAGATATCGATGTACTGCTGCAGCCACTCTATCAGGAA
GCGCTGGCACCGCTGCCTGCTCAGCGTCGGCAACTGTCACAATTGATCAGCGCCATGCGCGACGATGCGGAACGGCTGCT
GCTCGACCATAACGAGGCGCTGGCTAGCGTTCGTGAACAGACCCGGCAGGGCATGCTGCGGGTTTACGTGCTGCTGTTCG
TGCTGATGATATTGATCATGCTGGCAGGAACCTATCTTGTCATGGCGTTGTGGCGCGAGGCGCGCTCACGTGCCCGCCAC
GGTGAGCGTTTGCAGCGGCAGTCTCAGGAACTTCAGCGTGCTGTGCAGCAGGCAGAAGCGGCGAGTCAGTCCAAGTCGGA
ATTCATGGCAATCATGAGTCACGAGGTCCGCACCCCGCTCAATGGTGTGGTGGGTATGCTCGATGTGCTCGAGGATGAGC
CTTGTCAGGAAAAGCGTGAGCAGCACTTCGCGACCCTGAGGGAAAGCACCGCCTCGCTGCGCGCGGTTATCAATGATGTA
CTGGACTACTCGAAGATCGAAGCAGGACGTCTTGATCTTGAGCATTCGCCGTTTCCCTTGACGCGCATGGTCTCGCGGCT
TGCCGAAGGATATCAATCACGTCAGACCAGTGACGTGTCGCTCATCGTGCAGTTAGGTGATGACTTGCCTCCGGTGGTGA
TCGGTGATGCGACTCGCCTGCGACAAGTGTTGATGAACCTGATGGACAATGCCTTCAAGTTTACCCAGGTGGGCAGTATT
ACGCTCTCTGTTCAATCGCGAAAGCCGGCGACGATCTTTTTCGAGGTGCGTGATACCGGTGTCGGCATCGACAAGCAGGT
CCAGGCCGCGCTTTTCGAACCCTTCACTCAGGTGGATACCTCTCTGTCACGGCGCCATGAGGGGACCGGCCTTGGCCTGG
CGATTTGCTATCGGCTGGTAGAAGCCATGGGGGGGCACCTTGAATTGAACAGTATGCCGGACCTGGGCAGCGTCTTTCAC
TTCTGTCTTCCACTGAGTGCCGCCGAGGGTGTCAGCGAGCGTTTGCTCGACGATCCGTCTGAAGCACTGGCGTCACGACA
TCTGCTGGTGGTGGAAGACAACCCTATCAATCGGGATCTGGTGGCCGCCTTGCTCAAGCGCCTCGGTCAGACCTTCGATC
TTGCCGAAGACGGAGAGCAGGGGCTGGCGGCGATGAAGTGCAAGGACTATGACCTGGTGCTGATGGATATGCAGATGCCT
TGCATGGATGGCGTGGAGACGACTCGGCGCTTTCGTGCCGAGGAGGGGGAGGGTCACCTGCCTATCGTGGCCATGACGGC
CAACGTCATGCCGGAGCATCGGCAGGCATGCCGTGAGGCGGGAATGGACGACATTCTGAGCAAGCCTTTCACTCGACACG
AGTTGGCGAATGTTCTTCGTGCCTATCCACTCAGGCGTCATCAGGCTGCATCACATGTCGTGCAGCTTGACCACGCGCCC
GAGCAGGTGGCCGATGCTGACGCCGCCAGGCCCGCGGAGGATCGCAGCTGCGTCGGCGTGGGGGGCGGCCTGGATGCTGA
CACCGTGACCGAACTCGAGCAGAGCCTGGAGCATGAGACGTTGAAGACGCTGCTCGCAGCGTTTTTCTCACGTCTCGATG
GTCGGGTCGAAGTGTTGCGCGAGGCTGTCGATGGCAGTGACCGTGAGCGGATCAAGCGCGAGGCGCACTCGCTCAAGGGC
GCGGCGGCCTCGATGGGGTGTCGGCAGCTTGCCGCAGAAGCGGCGCGCCTAGAGCAGTTGGCGCCGAATGCCGAAATGTC
GCACTGTCGCGCGCAAATTGCCCGTATCGGACGAGGGGGGAGTGACGCGGTTTGCCTATGGCGTGGCAGGGGGGTCGATC
TGTCTTGA

Upstream 100 bases:

>100_bases
TGTGACCGCCTTCCAGCGCCACGATCGACTGCGACATGAAGGGCTGGAGAACGTCACCTGGGCGATCTATCAACTGGATC
GTCAATCACGTGAAGTTGAA

Downstream 100 bases:

>100_bases
GCGGCACCGATGCATAAGGTCTTGTCGCAGTGGCTCCGGCGATGAATCTTGGCGTCCGAGTGGCGCACGTCAGGTACCTA
GGAGGCGGGGCCGCCGCCCG

Product: Hpt sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MALEQVESRPTHGVSGTRGELSSWTRLMERFDILYGRIKLLQQGQYRQYLASQPELLEALWHLDARLEDIDVLLQPLYQE
ALAPLPAQRRQLSQLISAMRDDAERLLLDHNEALASVREQTRQGMLRVYVLLFVLMILIMLAGTYLVMALWREARSRARH
GERLQRQSQELQRAVQQAEAASQSKSEFMAIMSHEVRTPLNGVVGMLDVLEDEPCQEKREQHFATLRESTASLRAVINDV
LDYSKIEAGRLDLEHSPFPLTRMVSRLAEGYQSRQTSDVSLIVQLGDDLPPVVIGDATRLRQVLMNLMDNAFKFTQVGSI
TLSVQSRKPATIFFEVRDTGVGIDKQVQAALFEPFTQVDTSLSRRHEGTGLGLAICYRLVEAMGGHLELNSMPDLGSVFH
FCLPLSAAEGVSERLLDDPSEALASRHLLVVEDNPINRDLVAALLKRLGQTFDLAEDGEQGLAAMKCKDYDLVLMDMQMP
CMDGVETTRRFRAEEGEGHLPIVAMTANVMPEHRQACREAGMDDILSKPFTRHELANVLRAYPLRRHQAASHVVQLDHAP
EQVADADAARPAEDRSCVGVGGGLDADTVTELEQSLEHETLKTLLAAFFSRLDGRVEVLREAVDGSDRERIKREAHSLKG
AAASMGCRQLAAEAARLEQLAPNAEMSHCRAQIARIGRGGSDAVCLWRGRGVDLS

Sequences:

>Translated_695_residues
MALEQVESRPTHGVSGTRGELSSWTRLMERFDILYGRIKLLQQGQYRQYLASQPELLEALWHLDARLEDIDVLLQPLYQE
ALAPLPAQRRQLSQLISAMRDDAERLLLDHNEALASVREQTRQGMLRVYVLLFVLMILIMLAGTYLVMALWREARSRARH
GERLQRQSQELQRAVQQAEAASQSKSEFMAIMSHEVRTPLNGVVGMLDVLEDEPCQEKREQHFATLRESTASLRAVINDV
LDYSKIEAGRLDLEHSPFPLTRMVSRLAEGYQSRQTSDVSLIVQLGDDLPPVVIGDATRLRQVLMNLMDNAFKFTQVGSI
TLSVQSRKPATIFFEVRDTGVGIDKQVQAALFEPFTQVDTSLSRRHEGTGLGLAICYRLVEAMGGHLELNSMPDLGSVFH
FCLPLSAAEGVSERLLDDPSEALASRHLLVVEDNPINRDLVAALLKRLGQTFDLAEDGEQGLAAMKCKDYDLVLMDMQMP
CMDGVETTRRFRAEEGEGHLPIVAMTANVMPEHRQACREAGMDDILSKPFTRHELANVLRAYPLRRHQAASHVVQLDHAP
EQVADADAARPAEDRSCVGVGGGLDADTVTELEQSLEHETLKTLLAAFFSRLDGRVEVLREAVDGSDRERIKREAHSLKG
AAASMGCRQLAAEAARLEQLAPNAEMSHCRAQIARIGRGGSDAVCLWRGRGVDLS
>Mature_694_residues
ALEQVESRPTHGVSGTRGELSSWTRLMERFDILYGRIKLLQQGQYRQYLASQPELLEALWHLDARLEDIDVLLQPLYQEA
LAPLPAQRRQLSQLISAMRDDAERLLLDHNEALASVREQTRQGMLRVYVLLFVLMILIMLAGTYLVMALWREARSRARHG
ERLQRQSQELQRAVQQAEAASQSKSEFMAIMSHEVRTPLNGVVGMLDVLEDEPCQEKREQHFATLRESTASLRAVINDVL
DYSKIEAGRLDLEHSPFPLTRMVSRLAEGYQSRQTSDVSLIVQLGDDLPPVVIGDATRLRQVLMNLMDNAFKFTQVGSIT
LSVQSRKPATIFFEVRDTGVGIDKQVQAALFEPFTQVDTSLSRRHEGTGLGLAICYRLVEAMGGHLELNSMPDLGSVFHF
CLPLSAAEGVSERLLDDPSEALASRHLLVVEDNPINRDLVAALLKRLGQTFDLAEDGEQGLAAMKCKDYDLVLMDMQMPC
MDGVETTRRFRAEEGEGHLPIVAMTANVMPEHRQACREAGMDDILSKPFTRHELANVLRAYPLRRHQAASHVVQLDHAPE
QVADADAARPAEDRSCVGVGGGLDADTVTELEQSLEHETLKTLLAAFFSRLDGRVEVLREAVDGSDRERIKREAHSLKGA
AASMGCRQLAAEAARLEQLAPNAEMSHCRAQIARIGRGGSDAVCLWRGRGVDLS

Specific function: Involved in the positive regulation of synthesis of extracellular enzymes and polysaccharide, and hence in pathogenicity. Can restore function to the non-pathogenic mutant 8237 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=505, Percent_Identity=33.2673267326733, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI87081816, Length=522, Percent_Identity=31.4176245210728, Blast_Score=213, Evalue=4e-56,
Organism=Escherichia coli, GI1789149, Length=282, Percent_Identity=41.4893617021277, Blast_Score=202, Evalue=7e-53,
Organism=Escherichia coli, GI1788713, Length=492, Percent_Identity=29.6747967479675, Blast_Score=196, Evalue=5e-51,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=38.7755102040816, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=27.5720164609054, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=31.1965811965812, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=28.8617886178862, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786912, Length=258, Percent_Identity=25.1937984496124, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790436, Length=295, Percent_Identity=25.7627118644068, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1787894, Length=249, Percent_Identity=26.9076305220884, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786784, Length=124, Percent_Identity=36.2903225806452, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87082012, Length=129, Percent_Identity=30.2325581395349, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1786783, Length=235, Percent_Identity=24.6808510638298, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788191, Length=113, Percent_Identity=36.283185840708, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789402, Length=125, Percent_Identity=32.8, Blast_Score=62, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322000, Length=116, Percent_Identity=38.7931034482759, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322044, Length=253, Percent_Identity=29.2490118577075, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77430; Mature: 77298

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALEQVESRPTHGVSGTRGELSSWTRLMERFDILYGRIKLLQQGQYRQYLASQPELLEAL
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHH
WHLDARLEDIDVLLQPLYQEALAPLPAQRRQLSQLISAMRDDAERLLLDHNEALASVREQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TRQGMLRVYVLLFVLMILIMLAGTYLVMALWREARSRARHGERLQRQSQELQRAVQQAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASQSKSEFMAIMSHEVRTPLNGVVGMLDVLEDEPCQEKREQHFATLRESTASLRAVINDV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LDYSKIEAGRLDLEHSPFPLTRMVSRLAEGYQSRQTSDVSLIVQLGDDLPPVVIGDATRL
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCHHHH
RQVLMNLMDNAFKFTQVGSITLSVQSRKPATIFFEVRDTGVGIDKQVQAALFEPFTQVDT
HHHHHHHHHHHHHHHEECEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
SLSRRHEGTGLGLAICYRLVEAMGGHLELNSMPDLGSVFHFCLPLSAAEGVSERLLDDPS
HHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHHCCCHH
EALASRHLLVVEDNPINRDLVAALLKRLGQTFDLAEDGEQGLAAMKCKDYDLVLMDMQMP
HHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCEEEEECCCC
CMDGVETTRRFRAEEGEGHLPIVAMTANVMPEHRQACREAGMDDILSKPFTRHELANVLR
CCCHHHHHHHHHCCCCCCCCEEEEEEHHCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHH
AYPLRRHQAASHVVQLDHAPEQVADADAARPAEDRSCVGVGGGLDADTVTELEQSLEHET
HCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHH
LKTLLAAFFSRLDGRVEVLREAVDGSDRERIKREAHSLKGAAASMGCRQLAAEAARLEQL
HHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APNAEMSHCRAQIARIGRGGSDAVCLWRGRGVDLS
CCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
ALEQVESRPTHGVSGTRGELSSWTRLMERFDILYGRIKLLQQGQYRQYLASQPELLEAL
CCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHH
WHLDARLEDIDVLLQPLYQEALAPLPAQRRQLSQLISAMRDDAERLLLDHNEALASVREQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TRQGMLRVYVLLFVLMILIMLAGTYLVMALWREARSRARHGERLQRQSQELQRAVQQAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASQSKSEFMAIMSHEVRTPLNGVVGMLDVLEDEPCQEKREQHFATLRESTASLRAVINDV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LDYSKIEAGRLDLEHSPFPLTRMVSRLAEGYQSRQTSDVSLIVQLGDDLPPVVIGDATRL
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCHHHH
RQVLMNLMDNAFKFTQVGSITLSVQSRKPATIFFEVRDTGVGIDKQVQAALFEPFTQVDT
HHHHHHHHHHHHHHHEECEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
SLSRRHEGTGLGLAICYRLVEAMGGHLELNSMPDLGSVFHFCLPLSAAEGVSERLLDDPS
HHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHHCCCHH
EALASRHLLVVEDNPINRDLVAALLKRLGQTFDLAEDGEQGLAAMKCKDYDLVLMDMQMP
HHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCEEEEECCCC
CMDGVETTRRFRAEEGEGHLPIVAMTANVMPEHRQACREAGMDDILSKPFTRHELANVLR
CCCHHHHHHHHHCCCCCCCCEEEEEEHHCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHH
AYPLRRHQAASHVVQLDHAPEQVADADAARPAEDRSCVGVGGGLDADTVTELEQSLEHET
HCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHH
LKTLLAAFFSRLDGRVEVLREAVDGSDRERIKREAHSLKGAAASMGCRQLAAEAARLEQL
HHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APNAEMSHCRAQIARIGRGGSDAVCLWRGRGVDLS
CCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1645442 [H]