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The map label for this gene is hcr [H]

Identifier: 92113133

GI number: 92113133

Start: 1132833

End: 1133939

Strand: Direct

Name: hcr [H]

Synonym: Csal_1005

Alternate gene names: 92113133

Gene position: 1132833-1133939 (Clockwise)

Preceding gene: 92113131

Following gene: 92113135

Centisome position: 30.64

GC content: 61.07

Gene sequence:

>1107_bases
ATGACCCAGAATTTCTTCAATCCCGTCACGACCCAGACCTGGACGAACGGGCGCCACAACGTGCGCTGCGTGAAGGTCAT
CCAGGAAACCTGGGACGTTCGCACTTTCTGCTTCATGGCCGATCAGCCAGTGCTGTTCTTCTTCAAGCCGGGGCAGTTCG
TGACCCTGGAGCTGGAGATCGACGGCGAAGCGGTGATGCGGTCCTACACGATCTCCAGTTCGCCCTCCGTGCCCTACAGC
TTTTCGATCACCGTCAAGCGACTGCCCGACGGGCGTGTCTCCAACTGGCTGCACGAAAACCTGCAGGTGGGCAGCGAGCT
GGTGGTGCACGGCCCGGTCGGGGATTTCAATGTCATCGACTATCCCGCCGACAAGGTGCTCATGCTGTCCGGCGGGGTCG
GCGTCACGCCCTTGATGTCGATGACGCGCTGGTTCTTCGACACCAACGCCAATGTCGATCTGCAGTTCGTGCACAGCGCG
CGCACGCCTCGCGACATCATCTTCCACCGCGAACTCGAGCACATCTTCTCGCGAATTCCCGATTTCCGGCTGCATATCGT
CTGCGAGCGTGGTGATGAAAGCGGCGAACCCTGGGCGGGATTCCGCGGCTACCTGGCGCAGGCGATGCTCGAATTGATGG
TGCCGGATTACCTGGAGCGCGAAATTTTCTGTTGCGGGCCCACGCCGTACATGAAGGCCGTCAAGCAGGTGCTGAAGAGC
AACGGCTTCGACATGAGCCACTATCACGAGGAGTCGTTCGGGGCCACGCCCGCCGATGTCCGGGCGGATGTGGAGGAACT
TGCCGAGCAGGCCGAGGCGGAGATGGAAGCCGTCGATACCGCCGACATGCTGCAGGTCGAATTCAGCAACAGTGGCAAGA
GCATTCGCATCATGCCCGAAGAGACCGTGCACGCCGCCGCCGCCAAGCTGGGCCTGCACATCCCCAAGGCCTGTGGCATG
GGTATCTGCGGTACCTGCAAGGTCAAGAAGCTTGCCGGCGAGGTCACCATGGAGCACAACGGCGGTATCACCGAAGAGGA
CGAGGCAGACGGTTATATCCTGAGCTGCTGCAGCACGCCCAAGAGTCATGTCGCCATCGAGTTCTGA

Upstream 100 bases:

>100_bases
GCTGGCATGCGTGAGTCGTTGGCAGGCAAGTGGCCACTGAGCCGCATGATCACAATGCGCTGAAACGTCGGATACCGTCG
CGCGACCAGGTAGACTTTCC

Downstream 100 bases:

>100_bases
GGCCCGGCATCGATACATAGGCCCGGCATGGCCGGGCGCTCAGCGTGACTCCGGGGAGGGTGTGCCCAGACGTTCGGTCG
CTCGGGCGTGGCGGAGTTCA

Product: oxidoreductase FAD-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MTQNFFNPVTTQTWTNGRHNVRCVKVIQETWDVRTFCFMADQPVLFFFKPGQFVTLELEIDGEAVMRSYTISSSPSVPYS
FSITVKRLPDGRVSNWLHENLQVGSELVVHGPVGDFNVIDYPADKVLMLSGGVGVTPLMSMTRWFFDTNANVDLQFVHSA
RTPRDIIFHRELEHIFSRIPDFRLHIVCERGDESGEPWAGFRGYLAQAMLELMVPDYLEREIFCCGPTPYMKAVKQVLKS
NGFDMSHYHEESFGATPADVRADVEELAEQAEAEMEAVDTADMLQVEFSNSGKSIRIMPEETVHAAAAKLGLHIPKACGM
GICGTCKVKKLAGEVTMEHNGGITEEDEADGYILSCCSTPKSHVAIEF

Sequences:

>Translated_368_residues
MTQNFFNPVTTQTWTNGRHNVRCVKVIQETWDVRTFCFMADQPVLFFFKPGQFVTLELEIDGEAVMRSYTISSSPSVPYS
FSITVKRLPDGRVSNWLHENLQVGSELVVHGPVGDFNVIDYPADKVLMLSGGVGVTPLMSMTRWFFDTNANVDLQFVHSA
RTPRDIIFHRELEHIFSRIPDFRLHIVCERGDESGEPWAGFRGYLAQAMLELMVPDYLEREIFCCGPTPYMKAVKQVLKS
NGFDMSHYHEESFGATPADVRADVEELAEQAEAEMEAVDTADMLQVEFSNSGKSIRIMPEETVHAAAAKLGLHIPKACGM
GICGTCKVKKLAGEVTMEHNGGITEEDEADGYILSCCSTPKSHVAIEF
>Mature_367_residues
TQNFFNPVTTQTWTNGRHNVRCVKVIQETWDVRTFCFMADQPVLFFFKPGQFVTLELEIDGEAVMRSYTISSSPSVPYSF
SITVKRLPDGRVSNWLHENLQVGSELVVHGPVGDFNVIDYPADKVLMLSGGVGVTPLMSMTRWFFDTNANVDLQFVHSAR
TPRDIIFHRELEHIFSRIPDFRLHIVCERGDESGEPWAGFRGYLAQAMLELMVPDYLEREIFCCGPTPYMKAVKQVLKSN
GFDMSHYHEESFGATPADVRADVEELAEQAEAEMEAVDTADMLQVEFSNSGKSIRIMPEETVHAAAAKLGLHIPKACGMG
ICGTCKVKKLAGEVTMEHNGGITEEDEADGYILSCCSTPKSHVAIEF

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI84875541, Length=256, Percent_Identity=25.78125, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787098, Length=342, Percent_Identity=28.9473684210526, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1787658, Length=361, Percent_Identity=28.2548476454294, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1788903, Length=211, Percent_Identity=26.5402843601896, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788104, Length=337, Percent_Identity=24.6290801186944, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790359, Length=232, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322146, Length=200, Percent_Identity=25.5, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323552, Length=215, Percent_Identity=23.7209302325581, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323510, Length=198, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 41164; Mature: 41033

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQNFFNPVTTQTWTNGRHNVRCVKVIQETWDVRTFCFMADQPVLFFFKPGQFVTLELEI
CCCCCCCCCCCCCCCCCCCCHHHHEEHHHHHCCEEEEEECCCCEEEEECCCCEEEEEEEE
DGEAVMRSYTISSSPSVPYSFSITVKRLPDGRVSNWLHENLQVGSELVVHGPVGDFNVID
CCHHHEEEEEECCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEE
YPADKVLMLSGGVGVTPLMSMTRWFFDTNANVDLQFVHSARTPRDIIFHRELEHIFSRIP
CCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCC
DFRLHIVCERGDESGEPWAGFRGYLAQAMLELMVPDYLEREIFCCGPTPYMKAVKQVLKS
CEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCEEEECCCHHHHHHHHHHHC
NGFDMSHYHEESFGATPADVRADVEELAEQAEAEMEAVDTADMLQVEFSNSGKSIRIMPE
CCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCH
ETVHAAAAKLGLHIPKACGMGICGTCKVKKLAGEVTMEHNGGITEEDEADGYILSCCSTP
HHHHHHHHHHCCCCCHHCCCCCCCCCCCEECCCEEEEECCCCCCCCCCCCCEEEEECCCC
KSHVAIEF
CCCEEEEC
>Mature Secondary Structure 
TQNFFNPVTTQTWTNGRHNVRCVKVIQETWDVRTFCFMADQPVLFFFKPGQFVTLELEI
CCCCCCCCCCCCCCCCCCCHHHHEEHHHHHCCEEEEEECCCCEEEEECCCCEEEEEEEE
DGEAVMRSYTISSSPSVPYSFSITVKRLPDGRVSNWLHENLQVGSELVVHGPVGDFNVID
CCHHHEEEEEECCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEE
YPADKVLMLSGGVGVTPLMSMTRWFFDTNANVDLQFVHSARTPRDIIFHRELEHIFSRIP
CCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCC
DFRLHIVCERGDESGEPWAGFRGYLAQAMLELMVPDYLEREIFCCGPTPYMKAVKQVLKS
CEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCEEEECCCHHHHHHHHHHHC
NGFDMSHYHEESFGATPADVRADVEELAEQAEAEMEAVDTADMLQVEFSNSGKSIRIMPE
CCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCH
ETVHAAAAKLGLHIPKACGMGICGTCKVKKLAGEVTMEHNGGITEEDEADGYILSCCSTP
HHHHHHHHHHCCCCCHHCCCCCCCCCCCEECCCEEEEECCCCCCCCCCCCCEEEEECCCC
KSHVAIEF
CCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]