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The map label for this gene is cyoB [H]

Identifier: 92113083

GI number: 92113083

Start: 1073011

End: 1074990

Strand: Direct

Name: cyoB [H]

Synonym: Csal_0955

Alternate gene names: 92113083

Gene position: 1073011-1074990 (Clockwise)

Preceding gene: 92113082

Following gene: 92113084

Centisome position: 29.03

GC content: 59.04

Gene sequence:

>1980_bases
ATGTTCGGAAAACTTGGACTCGACGATATTCCCTATCACGAGCCGATCATCGTCGTGACGGCCATCGCCATGGCGCTCGG
TGGCTTGCTCGTCGTCGGCGCGCTGACGTACTTCAAGAAGTGGAAGTGGCTGTGGACGGAGTGGTTGACTTCCGTCGACC
ACAAGAAGCTGGGGATCATGTATTTCCTCGTGGCCCTGGTCATGCTGCTGCGCGGCTTTGCCGATGCCATCATGATGCGG
ACCCAACTGGCCATCGCGGCGGGTGGCTCCGAGGGGTATCTTCCGCCTCACCATTACGATCAGATCTTTACCGCCCACGG
CGTGATCATGATCTTCTTCGTCGCCATGCCCATGGTCATCGGCCTGATGAACCTGGTGGTGCCGTTGCAGATCGGTGCGC
GTGACGTCGCGTTCCCGTTCATGAACAACCTGAGCTTCTGGCTGTTCGTCGCGGGCGTGGCGCTGACCATGATTTCGCTG
CTCATCGGTGAGTACGGGCAGACCGGCTGGTTGGCCTACGCGCCATTGTCAGGGATACAGTACAGTCCCGGCGTGGGGGT
CGATTACTGGATATGGGGTCTGCAAATATCGGGGATCGGGACCACTCTGACGGGGATCAACTTCTTCGTCACCATCCTGA
AGATGCGTACCAAGGGTATGACGATGTTCCGCATGCCGATCTTCACCTGGACGTCGCTGTGCGCGAACATCCTCATCATC
GCTTCTTTCCCGATTCTGACCGCGACCATCGCGCTGTTGACGCTCGATCGTTACCTGGGGACGCACTTCTTCACGAACGA
CATGGGCGGCAACATGATGATGTACGTCAACCTCATCTGGGCCTGGGGCCATCCTGAGGTGTACATTCTCATTCTGCCGG
CCTTCGGGGTGTTCTCCGAGGTCATCGCGACCTTCGCCAAGAAGCGCCTGTTCGGTTACAACACCATGGTCTGGGCGACG
GCCTGCATCACCATCCTGTCGTTCATCGTGTGGCTGCACCACTTCTTCACCATGGGGGCGGGCGCCAACGTCAACGCTTT
CTTCGGCATCGCGACGATGATCATCGCCATCCCCACCGGGGTGAAGATCTTCAACTGGCTGTTCACCATGTACCGTGGCC
GCCTGGAGTTCACCTCGCCGGTGCTGTGGACGCTGGGCTTCATCATCACCTTCACCATCGGTGGCATGACGGGTGTGATG
CTGGCGGTGCCCGGTGCGAACTTCGTGCTGCACAACAGCCTGTTCGTCATCGCTCACTTCCATAACGTCATCATCGGCGG
CGTGGTGTTCGGCATGCTGGCGGGCCTGACCTACTGGTTCCCGAAAGCGTTCGGCTTCAAGCTCGATGAAAAGTGGGGCA
AGCGCTCCTTCTGGTTCTGGATCGTCGGCTTCTATCTGGCCTTCATGCCGCTCTACATCCTGAGCTTCATGGGCGCGGTA
CGTCGCATGCAGTCCTATGCGAACCCCGAATGGCAGCCGCTGATGATCGTGGCGTGGGTCGGTGCCGTGTGCATCCTGTT
CGGTATCGCCTGCACCGTGATCCAGTTCATCGTCAGTATCCGCGATCGCAAGAAGAACGCCGATATCACGGGCGATCCGT
GGGATGCGCGTACCCTGGAGTGGTCCACGTCTTCACCGGCGCCGTTCTACAACTTCGCGCATCTGCCCAATGTCGGCTCC
ATCGATGCCTTCTGGGAAGCGAAGAAAGAGAAAGGCATGGCGGCGGACAAGCCGACGCAGTACGAAGACATCCACATGCC
CAGGAACACCGTGGCGGGACCTGTCATCGGTCTGATCAGCATCGCGTTCGGCTTTGCGCTGGTCTGGCATATCTGGTGGC
TGGTCGGTGTCAGCGCGATTGGCATGTTCGTGGCCTTCATGTTCCGTGTCTTCAACGACGATATCGACTACTACGTCCCG
GCGGCGGAAGTCGAACGCATTGAGCGCGAGCACCACAAACGGCTGGAGATGCAGGCGTAA

Upstream 100 bases:

>100_bases
CACGACATCGTCGACAGTTTCCACGGTGGCAATGGGCAAGGTGGACACGGTGGCGGTCATGGCGAGACGACCATGAGCGC
AGAGGCAGCGGAGTAACATT

Downstream 100 bases:

>100_bases
TCATGACGACGCAAACCTTGAATCAGCATGACGCTCATGCCCATGACGGGCATGAGCACCACGATGCCGGTGGCATGAAG
GTATTCGGCTTCTGGGTCTA

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MFGKLGLDDIPYHEPIIVVTAIAMALGGLLVVGALTYFKKWKWLWTEWLTSVDHKKLGIMYFLVALVMLLRGFADAIMMR
TQLAIAAGGSEGYLPPHHYDQIFTAHGVIMIFFVAMPMVIGLMNLVVPLQIGARDVAFPFMNNLSFWLFVAGVALTMISL
LIGEYGQTGWLAYAPLSGIQYSPGVGVDYWIWGLQISGIGTTLTGINFFVTILKMRTKGMTMFRMPIFTWTSLCANILII
ASFPILTATIALLTLDRYLGTHFFTNDMGGNMMMYVNLIWAWGHPEVYILILPAFGVFSEVIATFAKKRLFGYNTMVWAT
ACITILSFIVWLHHFFTMGAGANVNAFFGIATMIIAIPTGVKIFNWLFTMYRGRLEFTSPVLWTLGFIITFTIGGMTGVM
LAVPGANFVLHNSLFVIAHFHNVIIGGVVFGMLAGLTYWFPKAFGFKLDEKWGKRSFWFWIVGFYLAFMPLYILSFMGAV
RRMQSYANPEWQPLMIVAWVGAVCILFGIACTVIQFIVSIRDRKKNADITGDPWDARTLEWSTSSPAPFYNFAHLPNVGS
IDAFWEAKKEKGMAADKPTQYEDIHMPRNTVAGPVIGLISIAFGFALVWHIWWLVGVSAIGMFVAFMFRVFNDDIDYYVP
AAEVERIEREHHKRLEMQA

Sequences:

>Translated_659_residues
MFGKLGLDDIPYHEPIIVVTAIAMALGGLLVVGALTYFKKWKWLWTEWLTSVDHKKLGIMYFLVALVMLLRGFADAIMMR
TQLAIAAGGSEGYLPPHHYDQIFTAHGVIMIFFVAMPMVIGLMNLVVPLQIGARDVAFPFMNNLSFWLFVAGVALTMISL
LIGEYGQTGWLAYAPLSGIQYSPGVGVDYWIWGLQISGIGTTLTGINFFVTILKMRTKGMTMFRMPIFTWTSLCANILII
ASFPILTATIALLTLDRYLGTHFFTNDMGGNMMMYVNLIWAWGHPEVYILILPAFGVFSEVIATFAKKRLFGYNTMVWAT
ACITILSFIVWLHHFFTMGAGANVNAFFGIATMIIAIPTGVKIFNWLFTMYRGRLEFTSPVLWTLGFIITFTIGGMTGVM
LAVPGANFVLHNSLFVIAHFHNVIIGGVVFGMLAGLTYWFPKAFGFKLDEKWGKRSFWFWIVGFYLAFMPLYILSFMGAV
RRMQSYANPEWQPLMIVAWVGAVCILFGIACTVIQFIVSIRDRKKNADITGDPWDARTLEWSTSSPAPFYNFAHLPNVGS
IDAFWEAKKEKGMAADKPTQYEDIHMPRNTVAGPVIGLISIAFGFALVWHIWWLVGVSAIGMFVAFMFRVFNDDIDYYVP
AAEVERIEREHHKRLEMQA
>Mature_659_residues
MFGKLGLDDIPYHEPIIVVTAIAMALGGLLVVGALTYFKKWKWLWTEWLTSVDHKKLGIMYFLVALVMLLRGFADAIMMR
TQLAIAAGGSEGYLPPHHYDQIFTAHGVIMIFFVAMPMVIGLMNLVVPLQIGARDVAFPFMNNLSFWLFVAGVALTMISL
LIGEYGQTGWLAYAPLSGIQYSPGVGVDYWIWGLQISGIGTTLTGINFFVTILKMRTKGMTMFRMPIFTWTSLCANILII
ASFPILTATIALLTLDRYLGTHFFTNDMGGNMMMYVNLIWAWGHPEVYILILPAFGVFSEVIATFAKKRLFGYNTMVWAT
ACITILSFIVWLHHFFTMGAGANVNAFFGIATMIIAIPTGVKIFNWLFTMYRGRLEFTSPVLWTLGFIITFTIGGMTGVM
LAVPGANFVLHNSLFVIAHFHNVIIGGVVFGMLAGLTYWFPKAFGFKLDEKWGKRSFWFWIVGFYLAFMPLYILSFMGAV
RRMQSYANPEWQPLMIVAWVGAVCILFGIACTVIQFIVSIRDRKKNADITGDPWDARTLEWSTSSPAPFYNFAHLPNVGS
IDAFWEAKKEKGMAADKPTQYEDIHMPRNTVAGPVIGLISIAFGFALVWHIWWLVGVSAIGMFVAFMFRVFNDDIDYYVP
AAEVERIEREHHKRLEMQA

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=510, Percent_Identity=39.8039215686275, Blast_Score=338, Evalue=8e-93,
Organism=Escherichia coli, GI1786634, Length=655, Percent_Identity=72.9770992366412, Blast_Score=1007, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=447, Percent_Identity=41.6107382550336, Blast_Score=340, Evalue=6e-94,
Organism=Saccharomyces cerevisiae, GI6226524, Length=326, Percent_Identity=44.7852760736196, Blast_Score=256, Evalue=7e-69,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=38.0566801619433, Blast_Score=144, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74159; Mature: 74159

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGKLGLDDIPYHEPIIVVTAIAMALGGLLVVGALTYFKKWKWLWTEWLTSVDHKKLGIM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YFLVALVMLLRGFADAIMMRTQLAIAAGGSEGYLPPHHYDQIFTAHGVIMIFFVAMPMVI
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLMNLVVPLQIGARDVAFPFMNNLSFWLFVAGVALTMISLLIGEYGQTGWLAYAPLSGIQ
HHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
YSPGVGVDYWIWGLQISGIGTTLTGINFFVTILKMRTKGMTMFRMPIFTWTSLCANILII
CCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
ASFPILTATIALLTLDRYLGTHFFTNDMGGNMMMYVNLIWAWGHPEVYILILPAFGVFSE
HHHHHHHHHHHHHHHHHHHCCHHEECCCCCCEEEEEEEEEECCCCCEEEEEECCHHHHHH
VIATFAKKRLFGYNTMVWATACITILSFIVWLHHFFTMGAGANVNAFFGIATMIIAIPTG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
VKIFNWLFTMYRGRLEFTSPVLWTLGFIITFTIGGMTGVMLAVPGANFVLHNSLFVIAHF
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHEEEEEECCCCEEEECCEEEEHHH
HNVIIGGVVFGMLAGLTYWFPKAFGFKLDEKWGKRSFWFWIVGFYLAFMPLYILSFMGAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RRMQSYANPEWQPLMIVAWVGAVCILFGIACTVIQFIVSIRDRKKNADITGDPWDARTLE
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
WSTSSPAPFYNFAHLPNVGSIDAFWEAKKEKGMAADKPTQYEDIHMPRNTVAGPVIGLIS
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IAFGFALVWHIWWLVGVSAIGMFVAFMFRVFNDDIDYYVPAAEVERIEREHHKRLEMQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFGKLGLDDIPYHEPIIVVTAIAMALGGLLVVGALTYFKKWKWLWTEWLTSVDHKKLGIM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YFLVALVMLLRGFADAIMMRTQLAIAAGGSEGYLPPHHYDQIFTAHGVIMIFFVAMPMVI
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLMNLVVPLQIGARDVAFPFMNNLSFWLFVAGVALTMISLLIGEYGQTGWLAYAPLSGIQ
HHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
YSPGVGVDYWIWGLQISGIGTTLTGINFFVTILKMRTKGMTMFRMPIFTWTSLCANILII
CCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
ASFPILTATIALLTLDRYLGTHFFTNDMGGNMMMYVNLIWAWGHPEVYILILPAFGVFSE
HHHHHHHHHHHHHHHHHHHCCHHEECCCCCCEEEEEEEEEECCCCCEEEEEECCHHHHHH
VIATFAKKRLFGYNTMVWATACITILSFIVWLHHFFTMGAGANVNAFFGIATMIIAIPTG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
VKIFNWLFTMYRGRLEFTSPVLWTLGFIITFTIGGMTGVMLAVPGANFVLHNSLFVIAHF
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHEEEEEECCCCEEEECCEEEEHHH
HNVIIGGVVFGMLAGLTYWFPKAFGFKLDEKWGKRSFWFWIVGFYLAFMPLYILSFMGAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RRMQSYANPEWQPLMIVAWVGAVCILFGIACTVIQFIVSIRDRKKNADITGDPWDARTLE
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
WSTSSPAPFYNFAHLPNVGSIDAFWEAKKEKGMAADKPTQYEDIHMPRNTVAGPVIGLIS
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IAFGFALVWHIWWLVGVSAIGMFVAFMFRVFNDDIDYYVPAAEVERIEREHHKRLEMQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]