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The map label for this gene is gap [H]

Identifier: 92113065

GI number: 92113065

Start: 1051835

End: 1052836

Strand: Direct

Name: gap [H]

Synonym: Csal_0937

Alternate gene names: 92113065

Gene position: 1051835-1052836 (Clockwise)

Preceding gene: 92113058

Following gene: 92113066

Centisome position: 28.45

GC content: 62.57

Gene sequence:

>1002_bases
ATGACGCTGCGAGTTGCAATCAATGGGTTTGGGCGTATCGGCCGTAACGCCTTGCGGGCTCTCTACGAGAACGGTTATCG
AGATCGCATCGAGGTCGTGGCCATCAATGATCTGGGGGACCCGTCGCTCAATGCCCACCTTCTCAAGCATGATAGCGTGC
ATGGGCATTTCATGTTCGACGTGACGCATGACAGCGAGTCGCTGAGCGTCGATGGCGATCGCATCCGCACGCTCTCCGAG
CGCGACCCGGCAGCCTTGCCGTGGGCCTCTCTCGATGTCGACCTGGTGATGGAATGCACCGGGCTGTTCACCTCGCGTGA
CGCCGCCGCCAAGCATCTCGATGCCGGTGCTCAGCGGGTGTTGATTTCCGCCCCCAGTGGCGATGCCGACGCCATGGTGG
TGTTCGGGGTCAACGAGCATGTGCTGACCAGCGAGCATCGGGTCGTCTCCAACGCTTCCTGCACCACCAATTGCCTGGCA
CCGGTTGCCAAGGCACTGCACGAAGGCGTGGGCATCGAGAGCGGCTTGATGACCACGGTGCACGCCTATACCAACGACCA
GAACCTGTCCGACGTCTATCACAAGGATCCGTACCGGGCGCGCAGCGCGACCCAGTCGATGATCCCCACCAAGACCGGTG
CCGCCGCGGCGGTGGGCAAGGTGCTGCCCGAGCTCGAGGGCAAGTTCGACGGCCTGGCGGTCCGCGTGCCGGTAATCAAC
GTGTCGCTGGTCGACTTGACCTTCACCGCCGGTCGCGAGACCACCAAGGAAGAAATCAACGAGATCGTCGAGAAGGCGGC
CGCCCAGTCGCCGGTGCTGGCGTCCAATGCCCAGCCGCTGGTGTCGATCGACTTCAACCACGATGCCAACTCGTCCACGT
TCGATGCCAATCACACCCGCGTCAACGGACGCCTGGTCAAGGTGATGGCGTGGTACGACAACGAGTGGGGCTTCTCCAAT
CGCATGCTGGATACGGCACTGGCCATGCACGCGGCCAAGTAA

Upstream 100 bases:

>100_bases
CGTGCGTCTTTCGCCCAAATTAAGGGAATAGTTGTAGTATTCTTCCAAAAGATGTCTATCGTATCCTTGGGTTCACGCCA
ATCAAAGAGAGGAAGCCATT

Downstream 100 bases:

>100_bases
CGCGGCAGTCGGTGACGTAACCACCCCGTGTGGGAGCGGCCGGACATACGTCTCGCGCACTCACGGCTCCGCTCGATCGT
TGTCCGTTCGCTCTCGCCCC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTLRVAINGFGRIGRNALRALYENGYRDRIEVVAINDLGDPSLNAHLLKHDSVHGHFMFDVTHDSESLSVDGDRIRTLSE
RDPAALPWASLDVDLVMECTGLFTSRDAAAKHLDAGAQRVLISAPSGDADAMVVFGVNEHVLTSEHRVVSNASCTTNCLA
PVAKALHEGVGIESGLMTTVHAYTNDQNLSDVYHKDPYRARSATQSMIPTKTGAAAAVGKVLPELEGKFDGLAVRVPVIN
VSLVDLTFTAGRETTKEEINEIVEKAAAQSPVLASNAQPLVSIDFNHDANSSTFDANHTRVNGRLVKVMAWYDNEWGFSN
RMLDTALAMHAAK

Sequences:

>Translated_333_residues
MTLRVAINGFGRIGRNALRALYENGYRDRIEVVAINDLGDPSLNAHLLKHDSVHGHFMFDVTHDSESLSVDGDRIRTLSE
RDPAALPWASLDVDLVMECTGLFTSRDAAAKHLDAGAQRVLISAPSGDADAMVVFGVNEHVLTSEHRVVSNASCTTNCLA
PVAKALHEGVGIESGLMTTVHAYTNDQNLSDVYHKDPYRARSATQSMIPTKTGAAAAVGKVLPELEGKFDGLAVRVPVIN
VSLVDLTFTAGRETTKEEINEIVEKAAAQSPVLASNAQPLVSIDFNHDANSSTFDANHTRVNGRLVKVMAWYDNEWGFSN
RMLDTALAMHAAK
>Mature_332_residues
TLRVAINGFGRIGRNALRALYENGYRDRIEVVAINDLGDPSLNAHLLKHDSVHGHFMFDVTHDSESLSVDGDRIRTLSER
DPAALPWASLDVDLVMECTGLFTSRDAAAKHLDAGAQRVLISAPSGDADAMVVFGVNEHVLTSEHRVVSNASCTTNCLAP
VAKALHEGVGIESGLMTTVHAYTNDQNLSDVYHKDPYRARSATQSMIPTKTGAAAAVGKVLPELEGKFDGLAVRVPVINV
SLVDLTFTAGRETTKEEINEIVEKAAAQSPVLASNAQPLVSIDFNHDANSSTFDANHTRVNGRLVKVMAWYDNEWGFSNR
MLDTALAMHAAK

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=328, Percent_Identity=45.1219512195122, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=47.112462006079, Blast_Score=269, Evalue=3e-72,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=51.3513513513513, Blast_Score=347, Evalue=7e-97,
Organism=Escherichia coli, GI1788079, Length=338, Percent_Identity=48.8165680473373, Blast_Score=284, Evalue=5e-78,
Organism=Caenorhabditis elegans, GI17534677, Length=335, Percent_Identity=47.7611940298507, Blast_Score=278, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=47.1641791044776, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI32566163, Length=335, Percent_Identity=45.6716417910448, Blast_Score=261, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI17568413, Length=335, Percent_Identity=45.6716417910448, Blast_Score=261, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6322468, Length=337, Percent_Identity=50.4451038575668, Blast_Score=318, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6321631, Length=340, Percent_Identity=49.7058823529412, Blast_Score=310, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=48.6404833836858, Blast_Score=301, Evalue=8e-83,
Organism=Drosophila melanogaster, GI85725000, Length=334, Percent_Identity=47.0059880239521, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI22023983, Length=334, Percent_Identity=47.0059880239521, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI17933600, Length=334, Percent_Identity=46.4071856287425, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI18110149, Length=334, Percent_Identity=46.4071856287425, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=44.2073170731707, Blast_Score=261, Evalue=6e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36015; Mature: 35884

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRVAINGFGRIGRNALRALYENGYRDRIEVVAINDLGDPSLNAHLLKHDSVHGHFMFD
CEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEEEEECCCCCEEEEEE
VTHDSESLSVDGDRIRTLSERDPAALPWASLDVDLVMECTGLFTSRDAAAKHLDAGAQRV
EECCCCCEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCEE
LISAPSGDADAMVVFGVNEHVLTSEHRVVSNASCTTNCLAPVAKALHEGVGIESGLMTTV
EEECCCCCCCEEEEEECCCCEECCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEE
HAYTNDQNLSDVYHKDPYRARSATQSMIPTKTGAAAAVGKVLPELEGKFDGLAVRVPVIN
EEECCCCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEE
VSLVDLTFTAGRETTKEEINEIVEKAAAQSPVLASNAQPLVSIDFNHDANSSTFDANHTR
EEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCCCCCCEE
VNGRLVKVMAWYDNEWGFSNRMLDTALAMHAAK
ECCEEEEEEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLRVAINGFGRIGRNALRALYENGYRDRIEVVAINDLGDPSLNAHLLKHDSVHGHFMFD
EEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEEEEECCCCCEEEEEE
VTHDSESLSVDGDRIRTLSERDPAALPWASLDVDLVMECTGLFTSRDAAAKHLDAGAQRV
EECCCCCEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCEE
LISAPSGDADAMVVFGVNEHVLTSEHRVVSNASCTTNCLAPVAKALHEGVGIESGLMTTV
EEECCCCCCCEEEEEECCCCEECCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEE
HAYTNDQNLSDVYHKDPYRARSATQSMIPTKTGAAAAVGKVLPELEGKFDGLAVRVPVIN
EEECCCCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEE
VSLVDLTFTAGRETTKEEINEIVEKAAAQSPVLASNAQPLVSIDFNHDANSSTFDANHTR
EEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCCCCCCEE
VNGRLVKVMAWYDNEWGFSNRMLDTALAMHAAK
ECCEEEEEEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045900; 10984043 [H]