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The map label for this gene is apaH

Identifier: 92113050

GI number: 92113050

Start: 1036192

End: 1037010

Strand: Direct

Name: apaH

Synonym: Csal_0922

Alternate gene names: 92113050

Gene position: 1036192-1037010 (Clockwise)

Preceding gene: 92113049

Following gene: 92113051

Centisome position: 28.03

GC content: 69.47

Gene sequence:

>819_bases
ATGTCGACGTATGCCATCGGCGATTTGCAGGGATGCCACGCGGAGTTCGAGGCCTTGCTGGAACGCATCGCCTTCGAGCC
GCGCCGTGATCGGTTATGGCTGGTAGGCGACCTGGTCAACCGCGGCCCGGGGTCGCTGGCGTGCTTGCGCGCGGTCAAGG
CGCTGGGGGACAGCGCCCGCGTGGTACTGGGCAACCATGACCTGCACCTGCTGGCGGCGGCGTGGGCCGGCGCCCCGCTG
AAGCGTTCCGATACGCTGGCGCCGATCCTCGAGGCCGACGACCGCGACGAGCTGCTCGACTGGTTGCGTCGGCAGCCCTT
GCTGGTGCGCGATGACGAGCTGGACGCGGTGATGACCCATGCCGGGCTTCCGCCGCATTGGTCGGTGACGCAGGCGGCCG
AGCATGCCGCCGAGGTCGAGCGAGCGTTGCGCGGCGAGGCGGTGGGCGACTTCCTGGCGGCGATGTATGGCAACTCGCCG
GCCCGCTGGACCGACGAGCTGGAGGGGATCGACCGCCTGCGGGTGATCGTCAATACCTTCACGCGCATGCGCTTCATCGC
CGCCGACGGCACGCTCGACTTTGCCGCCAAGGAAGGACTGGACAGTGCGCCCGAAGGTTTCGCGCCCTGGTTCACCTATG
CGCGAGACGATGATCCTCGTATCGTGTTCGGTCATTGGGCGGCGCTGCAGGGGGCGACGCCCGGCGCGCGGGTCCGTGCC
CTGGCGCTGGACACCGGCTGCGTGTGGGGCGGTGCCTTGACCGCGCTCGACCTGGTCAGCGGCGAGTACCATGTCGAACC
GGCCCACGCCTCACGCTGA

Upstream 100 bases:

>100_bases
TCAGGTGCATTGATCGGGGGAGGGGGCGGGCCTGCAGGCCACCAGGCATGAAGGGCAGTCCCCGGCTTGTTCCAGCCACC
AAGACCGTTCAGGAGAGACT

Downstream 100 bases:

>100_bases
CACCTGCCATCCGAGGAGCGTTTTGATGACCCAAGAGACTGCGTTTACCCATCTCGCGCCGAGCACGCTCGTGCATTGGC
TCGACACGGCCTGCGAGCTG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSTYAIGDLQGCHAEFEALLERIAFEPRRDRLWLVGDLVNRGPGSLACLRAVKALGDSARVVLGNHDLHLLAAAWAGAPL
KRSDTLAPILEADDRDELLDWLRRQPLLVRDDELDAVMTHAGLPPHWSVTQAAEHAAEVERALRGEAVGDFLAAMYGNSP
ARWTDELEGIDRLRVIVNTFTRMRFIAADGTLDFAAKEGLDSAPEGFAPWFTYARDDDPRIVFGHWAALQGATPGARVRA
LALDTGCVWGGALTALDLVSGEYHVEPAHASR

Sequences:

>Translated_272_residues
MSTYAIGDLQGCHAEFEALLERIAFEPRRDRLWLVGDLVNRGPGSLACLRAVKALGDSARVVLGNHDLHLLAAAWAGAPL
KRSDTLAPILEADDRDELLDWLRRQPLLVRDDELDAVMTHAGLPPHWSVTQAAEHAAEVERALRGEAVGDFLAAMYGNSP
ARWTDELEGIDRLRVIVNTFTRMRFIAADGTLDFAAKEGLDSAPEGFAPWFTYARDDDPRIVFGHWAALQGATPGARVRA
LALDTGCVWGGALTALDLVSGEYHVEPAHASR
>Mature_271_residues
STYAIGDLQGCHAEFEALLERIAFEPRRDRLWLVGDLVNRGPGSLACLRAVKALGDSARVVLGNHDLHLLAAAWAGAPLK
RSDTLAPILEADDRDELLDWLRRQPLLVRDDELDAVMTHAGLPPHWSVTQAAEHAAEVERALRGEAVGDFLAAMYGNSPA
RWTDELEGIDRLRVIVNTFTRMRFIAADGTLDFAAKEGLDSAPEGFAPWFTYARDDDPRIVFGHWAALQGATPGARVRAL
ALDTGCVWGGALTALDLVSGEYHVEPAHASR

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family

Homologues:

Organism=Escherichia coli, GI1786234, Length=274, Percent_Identity=50.7299270072993, Blast_Score=265, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APAH_CHRSD (Q1QZ29)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_572978.1
- ProteinModelPortal:   Q1QZ29
- SMR:   Q1QZ29
- STRING:   Q1QZ29
- GeneID:   4027429
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_0922
- NMPDR:   fig|290398.4.peg.914
- eggNOG:   COG0639
- HOGENOM:   HBG724457
- OMA:   LVFGHWA
- ProtClustDB:   PRK00166
- BioCyc:   CSAL290398:CSAL_0922-MONOMER
- HAMAP:   MF_00199
- InterPro:   IPR004617
- InterPro:   IPR004843
- PIRSF:   PIRSF000903
- TIGRFAMs:   TIGR00668

Pfam domain/function: PF00149 Metallophos

EC number: =3.6.1.41

Molecular weight: Translated: 29679; Mature: 29548

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTYAIGDLQGCHAEFEALLERIAFEPRRDRLWLVGDLVNRGPGSLACLRAVKALGDSAR
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCHHHHHHHHHHCCCCCE
VVLGNHDLHLLAAAWAGAPLKRSDTLAPILEADDRDELLDWLRRQPLLVRDDELDAVMTH
EEECCCCEEEEEEHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCEEECCCHHHHHHH
AGLPPHWSVTQAAEHAAEVERALRGEAVGDFLAAMYGNSPARWTDELEGIDRLRVIVNTF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TRMRFIAADGTLDFAAKEGLDSAPEGFAPWFTYARDDDPRIVFGHWAALQGATPGARVRA
HHHEEEECCCCEEHHHHCCCCCCCCCCCCCEECCCCCCCCEEEEEHHHHCCCCCCCEEEE
LALDTGCVWGGALTALDLVSGEYHVEPAHASR
EEEECCCCHHHHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure 
STYAIGDLQGCHAEFEALLERIAFEPRRDRLWLVGDLVNRGPGSLACLRAVKALGDSAR
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCHHHHHHHHHHCCCCCE
VVLGNHDLHLLAAAWAGAPLKRSDTLAPILEADDRDELLDWLRRQPLLVRDDELDAVMTH
EEECCCCEEEEEEHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCEEECCCHHHHHHH
AGLPPHWSVTQAAEHAAEVERALRGEAVGDFLAAMYGNSPARWTDELEGIDRLRVIVNTF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TRMRFIAADGTLDFAAKEGLDSAPEGFAPWFTYARDDDPRIVFGHWAALQGATPGARVRA
HHHEEEECCCCEEHHHHCCCCCCCCCCCCCEECCCCCCCCEEEEEHHHHCCCCCCCEEEE
LALDTGCVWGGALTALDLVSGEYHVEPAHASR
EEEECCCCHHHHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA