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The map label for this gene is rsmA

Identifier: 92113048

GI number: 92113048

Start: 1034876

End: 1035724

Strand: Direct

Name: rsmA

Synonym: Csal_0920

Alternate gene names: 92113048

Gene position: 1034876-1035724 (Clockwise)

Preceding gene: 92113047

Following gene: 92113049

Centisome position: 27.99

GC content: 64.31

Gene sequence:

>849_bases
ATGCCCGATTTCCCCAAGGAACACGCAACGCCCATGTCCAATCGCCCTCCGGCCCATCAGGCCCGTAAACGCTTCGGCCA
GAATTTCTTGCGCGACACCGGCGTGATCGATCGTATCGTTCGCGTTATCGCGCCGCGTTCCGACCAGCGGCTGATCGAGA
TCGGCCCGGGTCAGGGCGCCTTGACCGAGCCGTTGCTGGACGCCGTCGGTGCACTGGAAGTCATCGAACTCGATCGCGAC
CTGATACCCGGGCTGCGGGTGCAGTTCTTCAATTACCCCGACTTCGTCATCCACGAAGGGGATGCGCTGCAGTTCGATTT
CGCGGCGCTGGCTGCGGAGGGCGAGACGCCCGGCAAGCCTCTGCGGGTCATCGGCAACCTGCCCTACAACATTTCCACGC
CCCTGATCTTCCACCTGCTGACGGCGCGTGGTGCCATCGCCGACATGCACTTCATGCTGCAGCGGGAAGTGGTCGAGCGT
CTGGCCGCGACGCCGGGCAGTGCGGCCTGGGGGCGCTTGTCGGTGATGACGCAGTATCATTGCCGCGTGGACAATCTTTT
CGTGGTGCCTGCGGAAGCCTTCACGCCGCGTCCCAAGGTGGAATCGGCGATCGTGCGCCTGATACCGCATGACGAACCGC
CGCACGTGGCCCACGACGAGGCGCTGTTCGGCGATATCGTGCGCGAAGCCTTCGGTCAGCGGCGCAAGACGCTGCGCAAC
AATCTCAAGACACGCCTCGACGACACGGCCTGGGCGGCGCTGGACATCGATCCCGGCCGTCGTCCGCAGACGCTCAGCGT
CGAGGAATTGGTACGTATCGCCAACCATGTGGCGGAGACGGCACCATGA

Upstream 100 bases:

>100_bases
GCTCGATCTGGCCGGAAGCGGCCGGGCCGAGGCCGGCAGCCTGCGCGTGGCGCTCGATGTCGCCGTCCGCATGGTCCGTG
GTGGCACGTCTCGCCCCTGA

Downstream 100 bases:

>100_bases
GCGAGCTCGTCGAGCACATCCAGGTGCATGTCGAACCCGAATACCAGGCGGGAGAGTCCGCGCCCGGCGACCAGCGTTAC
GTGTTCAGCTACACGATCAC

Product: dimethyladenosine transferase

Products: NA

Alternate protein names: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase; 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MPDFPKEHATPMSNRPPAHQARKRFGQNFLRDTGVIDRIVRVIAPRSDQRLIEIGPGQGALTEPLLDAVGALEVIELDRD
LIPGLRVQFFNYPDFVIHEGDALQFDFAALAAEGETPGKPLRVIGNLPYNISTPLIFHLLTARGAIADMHFMLQREVVER
LAATPGSAAWGRLSVMTQYHCRVDNLFVVPAEAFTPRPKVESAIVRLIPHDEPPHVAHDEALFGDIVREAFGQRRKTLRN
NLKTRLDDTAWAALDIDPGRRPQTLSVEELVRIANHVAETAP

Sequences:

>Translated_282_residues
MPDFPKEHATPMSNRPPAHQARKRFGQNFLRDTGVIDRIVRVIAPRSDQRLIEIGPGQGALTEPLLDAVGALEVIELDRD
LIPGLRVQFFNYPDFVIHEGDALQFDFAALAAEGETPGKPLRVIGNLPYNISTPLIFHLLTARGAIADMHFMLQREVVER
LAATPGSAAWGRLSVMTQYHCRVDNLFVVPAEAFTPRPKVESAIVRLIPHDEPPHVAHDEALFGDIVREAFGQRRKTLRN
NLKTRLDDTAWAALDIDPGRRPQTLSVEELVRIANHVAETAP
>Mature_281_residues
PDFPKEHATPMSNRPPAHQARKRFGQNFLRDTGVIDRIVRVIAPRSDQRLIEIGPGQGALTEPLLDAVGALEVIELDRDL
IPGLRVQFFNYPDFVIHEGDALQFDFAALAAEGETPGKPLRVIGNLPYNISTPLIFHLLTARGAIADMHFMLQREVVERL
AATPGSAAWGRLSVMTQYHCRVDNLFVVPAEAFTPRPKVESAIVRLIPHDEPPHVAHDEALFGDIVREAFGQRRKTLRNN
LKTRLDDTAWAALDIDPGRRPQTLSVEELVRIANHVAETAP

Specific function: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily

Homologues:

Organism=Homo sapiens, GI156415992, Length=279, Percent_Identity=34.7670250896057, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI7657198, Length=222, Percent_Identity=33.7837837837838, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1786236, Length=272, Percent_Identity=52.9411764705882, Blast_Score=276, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI25146882, Length=216, Percent_Identity=31.0185185185185, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25141369, Length=293, Percent_Identity=28.6689419795222, Blast_Score=103, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6324989, Length=224, Percent_Identity=29.9107142857143, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358017, Length=249, Percent_Identity=36.5461847389558, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357273, Length=291, Percent_Identity=31.6151202749141, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMA_CHRSD (Q1QZ31)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_572976.1
- ProteinModelPortal:   Q1QZ31
- SMR:   Q1QZ31
- STRING:   Q1QZ31
- GeneID:   4027427
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_0920
- NMPDR:   fig|290398.4.peg.912
- eggNOG:   COG0030
- HOGENOM:   HBG319664
- OMA:   RAENLTP
- BioCyc:   CSAL290398:CSAL_0920-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00607
- InterPro:   IPR023165
- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530
- Gene3D:   G3DSA:1.10.8.100
- PANTHER:   PTHR11727
- SMART:   SM00650
- TIGRFAMs:   TIGR00755

Pfam domain/function: PF00398 RrnaAD

EC number: =2.1.1.182

Molecular weight: Translated: 31423; Mature: 31292

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01131 RRNA_A_DIMETH

Important sites: BINDING 28-28 BINDING 30-30 BINDING 55-55 BINDING 76-76 BINDING 101-101 BINDING 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFPKEHATPMSNRPPAHQARKRFGQNFLRDTGVIDRIVRVIAPRSDQRLIEIGPGQGA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
LTEPLLDAVGALEVIELDRDLIPGLRVQFFNYPDFVIHEGDALQFDFAALAAEGETPGKP
HHHHHHHHHHHHHHHHHCHHHCCCCEEEEECCCCEEEECCCCCEEHHHHHHCCCCCCCCC
LRVIGNLPYNISTPLIFHLLTARGAIADMHFMLQREVVERLAATPGSAAWGRLSVMTQYH
EEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
CRVDNLFVVPAEAFTPRPKVESAIVRLIPHDEPPHVAHDEALFGDIVREAFGQRRKTLRN
CCCCCEEEEECHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NLKTRLDDTAWAALDIDPGRRPQTLSVEELVRIANHVAETAP
HHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDFPKEHATPMSNRPPAHQARKRFGQNFLRDTGVIDRIVRVIAPRSDQRLIEIGPGQGA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
LTEPLLDAVGALEVIELDRDLIPGLRVQFFNYPDFVIHEGDALQFDFAALAAEGETPGKP
HHHHHHHHHHHHHHHHHCHHHCCCCEEEEECCCCEEEECCCCCEEHHHHHHCCCCCCCCC
LRVIGNLPYNISTPLIFHLLTARGAIADMHFMLQREVVERLAATPGSAAWGRLSVMTQYH
EEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
CRVDNLFVVPAEAFTPRPKVESAIVRLIPHDEPPHVAHDEALFGDIVREAFGQRRKTLRN
CCCCCEEEEECHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NLKTRLDDTAWAALDIDPGRRPQTLSVEELVRIANHVAETAP
HHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA