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The map label for this gene is hemY [H]

Identifier: 92112924

GI number: 92112924

Start: 891294

End: 892724

Strand: Direct

Name: hemY [H]

Synonym: Csal_0796

Alternate gene names: 92112924

Gene position: 891294-892724 (Clockwise)

Preceding gene: 92112923

Following gene: 92112926

Centisome position: 24.11

GC content: 72.12

Gene sequence:

>1431_bases
ATGCAGCATGAAGAACAGCTCGATGCGACCGACCAGGCGGTCGGCGAGGCACGGCGCGACGTGGTCGTCGTCGGCGGCGG
GGCCAGCGGCCTGGCCGCTGCCCGGGCGGCGGCCAGGCGCGGGCTCGCTGTCAGCGTGCTCGAGCGCGGGTCGCACGCGG
GTGGCAATCTGCGCACCCATCGCGACGGGGCGTGGCAGGTCGAGGTCGGTCCCAACACGCTGGTGATGAAGCCGCCGCTG
CACACGCTGCTCGACGAGCTGGGACTGCTCGACGAGGCCCAGCCGGCCAATCCCGATGCGCGGCGTCGCTATATCGCCTT
CCATGGACGCCCGGTGGCCTTGCCCACTCATGTCCTCAAGGCGCCCGCCAACCCGTTGATCGGCCTGCGCGGCAGCTGGT
CCGTGCTGCGCGAGCCCTTTCGGGCGGGGCCGCCACGCGACGAGGAAAGCCTGGCGGACTTCGTCGTGCGACGCCTGGGA
CGCCACGTGCTCGACCATCTGGTCGACCCCTTTGTCTCAGGCGTTTATGCCGGCGATCCCGCCCGGCTCTCCGCGCAGGC
GGCGATGCCCCGGCTGGTGGCGCTGGAGCGCGAGTACGGCTCGCTGGTGCGAGGCGGGCTGCGCCGGCTACGCCAGTCGC
GTCGCGAGCCGCCCGCCCTGCCACGCGAGTGGCGCGGACAACTGGTGAGTTTCCCTGCCGGGCTGCAACGCCTTGCTGAG
CGGCTGGCGGAGGACATCGCCGATCAGCCCGGGGCGTCGGTACAGTGCGGCTGCGAGGTCGTCGCCGTGGGCCGCGAGGC
CGACGGCTGGCAGGTGGAAACGGCCGCCGGCCAGCGCATTCGCACGCGCGAACTGGTGCTGGCGGTGCCGGCCCCCACGG
CGGCGGCGCTGCTGGCCCCCCTCGACGCGGCCCTGGCTGCCCCCCTGGAGGAAATCGCCTATCCACCGGTCAACGCGGTC
TCGGTGGGATTTCGCCGGGCCGACGTCGACCATCCTCTCGATGGCTTCGGCATGTTGATTCCCGGGGTCGAGCGGCGGCG
TACGCTGGGGGCACTGTTTTCCTCGACGCTGTTCCCCGGGCGTGCGCCGTCGGATCATGTGCTGCTGACGGCCTTTCTGG
GAGGCCGGCGCCAGCCGGAGGCCGCCGCCGGCGACGATGCGGAGCAGGTCGCTCAGGTGGTGGCCGATCTCGGCGATTTG
CTGGGAATTCACGCCGAGCCGGTGTGGCAATGCGTGAGCCGCTGGCCACAGGCGATTCCGCAGTACGAGCGTGGGCACCT
GGCGCGGATTGCCGCCCTGGACGCGGCTCTGGAAGCGCATCCCGGCCTCTCGCTGCTCGGCAACTGGCGTGACGGCATCG
CGGTGGGGGATTGCCTGGAAAACGGCCGGCGTCTCGGCGAGCGGCTCGCCGAGACGCCGGATCGGCGCTGA

Upstream 100 bases:

>100_bases
ATGCCGAGTGCGTCGATGCGCCGCAAGCGTAGTGCCCCGCGAGCCGGCGGTGTCCGCTATGCTCGTCGTCTGAATGTCAG
GTGCGCCCAGGGGAGACGTC

Downstream 100 bases:

>100_bases
GGGCCGGTTACAGGCGTACCAGCATCTTGCCGGTATTGCCGCCTTCGAAGAGCTTGAGGAAGGCATCCGGCGTGCGCTCG
AGCCCGTCTTCGACCGTTTC

Product: protoporphyrinogen oxidase

Products: NA

Alternate protein names: PPO [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MQHEEQLDATDQAVGEARRDVVVVGGGASGLAAARAAARRGLAVSVLERGSHAGGNLRTHRDGAWQVEVGPNTLVMKPPL
HTLLDELGLLDEAQPANPDARRRYIAFHGRPVALPTHVLKAPANPLIGLRGSWSVLREPFRAGPPRDEESLADFVVRRLG
RHVLDHLVDPFVSGVYAGDPARLSAQAAMPRLVALEREYGSLVRGGLRRLRQSRREPPALPREWRGQLVSFPAGLQRLAE
RLAEDIADQPGASVQCGCEVVAVGREADGWQVETAAGQRIRTRELVLAVPAPTAAALLAPLDAALAAPLEEIAYPPVNAV
SVGFRRADVDHPLDGFGMLIPGVERRRTLGALFSSTLFPGRAPSDHVLLTAFLGGRRQPEAAAGDDAEQVAQVVADLGDL
LGIHAEPVWQCVSRWPQAIPQYERGHLARIAALDAALEAHPGLSLLGNWRDGIAVGDCLENGRRLGERLAETPDRR

Sequences:

>Translated_476_residues
MQHEEQLDATDQAVGEARRDVVVVGGGASGLAAARAAARRGLAVSVLERGSHAGGNLRTHRDGAWQVEVGPNTLVMKPPL
HTLLDELGLLDEAQPANPDARRRYIAFHGRPVALPTHVLKAPANPLIGLRGSWSVLREPFRAGPPRDEESLADFVVRRLG
RHVLDHLVDPFVSGVYAGDPARLSAQAAMPRLVALEREYGSLVRGGLRRLRQSRREPPALPREWRGQLVSFPAGLQRLAE
RLAEDIADQPGASVQCGCEVVAVGREADGWQVETAAGQRIRTRELVLAVPAPTAAALLAPLDAALAAPLEEIAYPPVNAV
SVGFRRADVDHPLDGFGMLIPGVERRRTLGALFSSTLFPGRAPSDHVLLTAFLGGRRQPEAAAGDDAEQVAQVVADLGDL
LGIHAEPVWQCVSRWPQAIPQYERGHLARIAALDAALEAHPGLSLLGNWRDGIAVGDCLENGRRLGERLAETPDRR
>Mature_476_residues
MQHEEQLDATDQAVGEARRDVVVVGGGASGLAAARAAARRGLAVSVLERGSHAGGNLRTHRDGAWQVEVGPNTLVMKPPL
HTLLDELGLLDEAQPANPDARRRYIAFHGRPVALPTHVLKAPANPLIGLRGSWSVLREPFRAGPPRDEESLADFVVRRLG
RHVLDHLVDPFVSGVYAGDPARLSAQAAMPRLVALEREYGSLVRGGLRRLRQSRREPPALPREWRGQLVSFPAGLQRLAE
RLAEDIADQPGASVQCGCEVVAVGREADGWQVETAAGQRIRTRELVLAVPAPTAAALLAPLDAALAAPLEEIAYPPVNAV
SVGFRRADVDHPLDGFGMLIPGVERRRTLGALFSSTLFPGRAPSDHVLLTAFLGGRRQPEAAAGDDAEQVAQVVADLGDL
LGIHAEPVWQCVSRWPQAIPQYERGHLARIAALDAALEAHPGLSLLGNWRDGIAVGDCLENGRRLGERLAETPDRR

Specific function: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. May have an essential extracellular function during development, possibly as a pheromone [H]

COG id: COG1232

COG function: function code H; Protoporphyrinogen oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protoporphyrinogen oxidase family [H]

Homologues:

Organism=Homo sapiens, GI170650615, Length=471, Percent_Identity=30.5732484076433, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI4506001, Length=471, Percent_Identity=30.5732484076433, Blast_Score=122, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24649745, Length=463, Percent_Identity=25.9179265658747, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR016040
- InterPro:   IPR004572 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: =1.3.3.4 [H]

Molecular weight: Translated: 51129; Mature: 51129

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHEEQLDATDQAVGEARRDVVVVGGGASGLAAARAAARRGLAVSVLERGSHAGGNLRTH
CCCHHHCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEC
RDGAWQVEVGPNTLVMKPPLHTLLDELGLLDEAQPANPDARRRYIAFHGRPVALPTHVLK
CCCCEEEEECCCEEEECCCHHHHHHHHCCCCCCCCCCCHHHCEEEEECCCCCCCHHHHHH
APANPLIGLRGSWSVLREPFRAGPPRDEESLADFVVRRLGRHVLDHLVDPFVSGVYAGDP
CCCCCCEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ARLSAQAAMPRLVALEREYGSLVRGGLRRLRQSRREPPALPREWRGQLVSFPAGLQRLAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHH
RLAEDIADQPGASVQCGCEVVAVGREADGWQVETAAGQRIRTRELVLAVPAPTAAALLAP
HHHHHHHCCCCCCEECCCEEEEECCCCCCCEEECCCCCCEEEEEEEEEECCCHHHHHHHH
LDAALAAPLEEIAYPPVNAVSVGFRRADVDHPLDGFGMLIPGVERRRTLGALFSSTLFPG
HHHHHHCCHHHHCCCCCCHHHHCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCC
RAPSDHVLLTAFLGGRRQPEAAAGDDAEQVAQVVADLGDLLGIHAEPVWQCVSRWPQAIP
CCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
QYERGHLARIAALDAALEAHPGLSLLGNWRDGIAVGDCLENGRRLGERLAETPDRR
CHHCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQHEEQLDATDQAVGEARRDVVVVGGGASGLAAARAAARRGLAVSVLERGSHAGGNLRTH
CCCHHHCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEC
RDGAWQVEVGPNTLVMKPPLHTLLDELGLLDEAQPANPDARRRYIAFHGRPVALPTHVLK
CCCCEEEEECCCEEEECCCHHHHHHHHCCCCCCCCCCCHHHCEEEEECCCCCCCHHHHHH
APANPLIGLRGSWSVLREPFRAGPPRDEESLADFVVRRLGRHVLDHLVDPFVSGVYAGDP
CCCCCCEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ARLSAQAAMPRLVALEREYGSLVRGGLRRLRQSRREPPALPREWRGQLVSFPAGLQRLAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHH
RLAEDIADQPGASVQCGCEVVAVGREADGWQVETAAGQRIRTRELVLAVPAPTAAALLAP
HHHHHHHCCCCCCEECCCEEEEECCCCCCCEEECCCCCCEEEEEEEEEECCCHHHHHHHH
LDAALAAPLEEIAYPPVNAVSVGFRRADVDHPLDGFGMLIPGVERRRTLGALFSSTLFPG
HHHHHHCCHHHHCCCCCCHHHHCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCC
RAPSDHVLLTAFLGGRRQPEAAAGDDAEQVAQVVADLGDLLGIHAEPVWQCVSRWPQAIP
CCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
QYERGHLARIAALDAALEAHPGLSLLGNWRDGIAVGDCLENGRRLGERLAETPDRR
CHHCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1372277; 8621504 [H]