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The map label for this gene is yfhK [H]

Identifier: 92112847

GI number: 92112847

Start: 802613

End: 804169

Strand: Direct

Name: yfhK [H]

Synonym: Csal_0715

Alternate gene names: 92112847

Gene position: 802613-804169 (Clockwise)

Preceding gene: 92112845

Following gene: 92112848

Centisome position: 21.71

GC content: 64.1

Gene sequence:

>1557_bases
ATGGCATCCACCCTCTTTCTGCATAGAATCGCGCTCATGGCCACTCAGGTCTCTCGCCGCTGGCGTCCCCGTTCATTGTT
GCAGTTGGTATTGCTCGCCTTCGTCATGGTGATGCTGCCGATTGCCGTTCTCATGTTTCAGGCCGGTCAGGCGCTTTCCG
AACTTTCGTCGCTGGCCGACGTGAGCGCACGCCAGGCGGTGGAACAAACCCGTCGTGCCCGTACCCTCAGCAATCTGGCC
CTGGAGATGGAGCGCAGTGCGCGCCAGTACGCGGTGCTCGAGCAAGAAGGGCTGCTCGATATCTACAACGAGAAGGCCGA
GCGCTACGCGGAACTGCTCGACGAGCACGCCCCCCTGCTGCCCGACGACCCCGACATTCCACGGCTGCGCGAGCAACTGG
GCGAACTCGAGGCCCTGCCGGACATGTCCATCGAGGAATTCCGCGAGCAACTGGCGGCGTTCGGCAACTTTTCCCAGCGC
ACCGACAACGTCCGCCAGGCCACCAACCAGCTCATCGACGACCGCATCGATGCCATTCGCGAGCGCGCCGGCACGGTGCG
CGGCCAGCTCTGGCTGCAGACCGCCGTGCTGGTGTCGGTGAGCCTGGTGCTCATGCTGTTCTTCACCTGGTTGATCATCC
GTCCCATTCGCCAGCTCGAACGGCGCATCTTCAGTCTGGGCAGCGGCATGGAACCCGCCTCGCCGCAGCATATCCAGGGG
CCGGCGGAGCTGGTCAGTCTGGGCGAGCGCCTGACCTGGCTCTCCGGGCGTCTCACCGAGCTGGAGGCGCAGAAGCAACA
GTTCCTGCGGCATATGTCCCATGAGCTGAAGACGCCGCTGGCCAGCGTGCGCGAAGGCACGGCGCTGCTGTCCGACGGCG
TGGTGGGCGAGCTGAGCGAGCGCCAGCGGGAAATCGTCGGCTTGATCGATGTCAGTGGTCAGGAACTGCAGGAGCTCATC
GAACAGCTGCTCGACTATAATCTCTTGCAGCACAGTCGCGGCCTCAAGGTGACGCGTTTCGATCTGGTCACGGTGATCCA
GGAGGTGCTCGCCAAGCATCGCCTGGCGCTCGACAAGAAGGGCATGCGGGTCGAATGGCCGCAGCATGCGCCACTCCCCT
GGCAGGCCGACCGCGAACGGACGGCCAGTATCCTGGACAACCTGGTTTCCAATGCCATCGCCTACGGCGAGGACGGCGGC
TATCTGGCGCTGCGGGTTCGCCAGCATCAGGCCTCGCTGATCGTCGACGTCGCCAATACCGGCGAACCCATCGACGACGA
GGATCGTGCGCATCTCTTCGAGGCATTCTATCAAGGCCGTATGCGGCGCAAGGGTGCCCTCAAGGGCTCGGGAATCGGGC
TGTCGGTGGCCGCCGACTGCGCCAGGGTCCAGCAAGGGCGGCTGGAACTGGTCGAGGATGACGATTTCCCGGTCTGCTTT
CGCCTGATATTGCCCGAGGTCTCGTCGGCGGAGGGAAACCCCGCCACCGATGACGCCTCCATAACGACGCCGGCCACACG
AATGCCGGCGCTTAACGCAAGGAACTCGAACCCATGA

Upstream 100 bases:

>100_bases
CGGGGCAAGCGAAGGGGCCATCACGAAGCGCTCGATCGGCGGGGCGACCAGAAGCCCGGCAGGCGAGTGTAACTCTGTTA
TCCTGTGCGGATAAGATTAC

Downstream 100 bases:

>100_bases
AAATCCGGATGCTGCTAGTGGCGCTATGCGCCAGCTCGCTCTTGACCGGTTGCCAGTGGCTGGCCCAGCAGCCGCCCCCG
CCGGAGCCCCCGGTCACCTC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MASTLFLHRIALMATQVSRRWRPRSLLQLVLLAFVMVMLPIAVLMFQAGQALSELSSLADVSARQAVEQTRRARTLSNLA
LEMERSARQYAVLEQEGLLDIYNEKAERYAELLDEHAPLLPDDPDIPRLREQLGELEALPDMSIEEFREQLAAFGNFSQR
TDNVRQATNQLIDDRIDAIRERAGTVRGQLWLQTAVLVSVSLVLMLFFTWLIIRPIRQLERRIFSLGSGMEPASPQHIQG
PAELVSLGERLTWLSGRLTELEAQKQQFLRHMSHELKTPLASVREGTALLSDGVVGELSERQREIVGLIDVSGQELQELI
EQLLDYNLLQHSRGLKVTRFDLVTVIQEVLAKHRLALDKKGMRVEWPQHAPLPWQADRERTASILDNLVSNAIAYGEDGG
YLALRVRQHQASLIVDVANTGEPIDDEDRAHLFEAFYQGRMRRKGALKGSGIGLSVAADCARVQQGRLELVEDDDFPVCF
RLILPEVSSAEGNPATDDASITTPATRMPALNARNSNP

Sequences:

>Translated_518_residues
MASTLFLHRIALMATQVSRRWRPRSLLQLVLLAFVMVMLPIAVLMFQAGQALSELSSLADVSARQAVEQTRRARTLSNLA
LEMERSARQYAVLEQEGLLDIYNEKAERYAELLDEHAPLLPDDPDIPRLREQLGELEALPDMSIEEFREQLAAFGNFSQR
TDNVRQATNQLIDDRIDAIRERAGTVRGQLWLQTAVLVSVSLVLMLFFTWLIIRPIRQLERRIFSLGSGMEPASPQHIQG
PAELVSLGERLTWLSGRLTELEAQKQQFLRHMSHELKTPLASVREGTALLSDGVVGELSERQREIVGLIDVSGQELQELI
EQLLDYNLLQHSRGLKVTRFDLVTVIQEVLAKHRLALDKKGMRVEWPQHAPLPWQADRERTASILDNLVSNAIAYGEDGG
YLALRVRQHQASLIVDVANTGEPIDDEDRAHLFEAFYQGRMRRKGALKGSGIGLSVAADCARVQQGRLELVEDDDFPVCF
RLILPEVSSAEGNPATDDASITTPATRMPALNARNSNP
>Mature_517_residues
ASTLFLHRIALMATQVSRRWRPRSLLQLVLLAFVMVMLPIAVLMFQAGQALSELSSLADVSARQAVEQTRRARTLSNLAL
EMERSARQYAVLEQEGLLDIYNEKAERYAELLDEHAPLLPDDPDIPRLREQLGELEALPDMSIEEFREQLAAFGNFSQRT
DNVRQATNQLIDDRIDAIRERAGTVRGQLWLQTAVLVSVSLVLMLFFTWLIIRPIRQLERRIFSLGSGMEPASPQHIQGP
AELVSLGERLTWLSGRLTELEAQKQQFLRHMSHELKTPLASVREGTALLSDGVVGELSERQREIVGLIDVSGQELQELIE
QLLDYNLLQHSRGLKVTRFDLVTVIQEVLAKHRLALDKKGMRVEWPQHAPLPWQADRERTASILDNLVSNAIAYGEDGGY
LALRVRQHQASLIVDVANTGEPIDDEDRAHLFEAFYQGRMRRKGALKGSGIGLSVAADCARVQQGRLELVEDDDFPVCFR
LILPEVSSAEGNPATDDASITTPATRMPALNARNSNP

Specific function: Probable member of a two-component regulatory system yfhA/yfhK. May activate yfhA by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082128, Length=471, Percent_Identity=44.5859872611465, Blast_Score=338, Evalue=4e-94,
Organism=Escherichia coli, GI1790861, Length=288, Percent_Identity=27.4305555555556, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=23.7885462555066, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=26.2773722627737, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=229, Percent_Identity=28.3842794759825, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789808, Length=307, Percent_Identity=25.7328990228013, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI48994928, Length=254, Percent_Identity=27.1653543307087, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=25.974025974026, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789149, Length=203, Percent_Identity=30.5418719211823, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI145693157, Length=210, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787894, Length=234, Percent_Identity=26.4957264957265, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58119; Mature: 57988

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50109 HIS_KIN ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTLFLHRIALMATQVSRRWRPRSLLQLVLLAFVMVMLPIAVLMFQAGQALSELSSLAD
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSARQAVEQTRRARTLSNLALEMERSARQYAVLEQEGLLDIYNEKAERYAELLDEHAPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
PDDPDIPRLREQLGELEALPDMSIEEFREQLAAFGNFSQRTDNVRQATNQLIDDRIDAIR
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ERAGTVRGQLWLQTAVLVSVSLVLMLFFTWLIIRPIRQLERRIFSLGSGMEPASPQHIQG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PAELVSLGERLTWLSGRLTELEAQKQQFLRHMSHELKTPLASVREGTALLSDGVVGELSE
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHCCCHHHHHH
RQREIVGLIDVSGQELQELIEQLLDYNLLQHSRGLKVTRFDLVTVIQEVLAKHRLALDKK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GMRVEWPQHAPLPWQADRERTASILDNLVSNAIAYGEDGGYLALRVRQHQASLIVDVANT
CCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCC
GEPIDDEDRAHLFEAFYQGRMRRKGALKGSGIGLSVAADCARVQQGRLELVEDDDFPVCF
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCHHHH
RLILPEVSSAEGNPATDDASITTPATRMPALNARNSNP
HHHHCHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
ASTLFLHRIALMATQVSRRWRPRSLLQLVLLAFVMVMLPIAVLMFQAGQALSELSSLAD
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSARQAVEQTRRARTLSNLALEMERSARQYAVLEQEGLLDIYNEKAERYAELLDEHAPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
PDDPDIPRLREQLGELEALPDMSIEEFREQLAAFGNFSQRTDNVRQATNQLIDDRIDAIR
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ERAGTVRGQLWLQTAVLVSVSLVLMLFFTWLIIRPIRQLERRIFSLGSGMEPASPQHIQG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PAELVSLGERLTWLSGRLTELEAQKQQFLRHMSHELKTPLASVREGTALLSDGVVGELSE
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHCCCHHHHHH
RQREIVGLIDVSGQELQELIEQLLDYNLLQHSRGLKVTRFDLVTVIQEVLAKHRLALDKK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GMRVEWPQHAPLPWQADRERTASILDNLVSNAIAYGEDGGYLALRVRQHQASLIVDVANT
CCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCC
GEPIDDEDRAHLFEAFYQGRMRRKGALKGSGIGLSVAADCARVQQGRLELVEDDDFPVCF
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCHHHH
RLILPEVSSAEGNPATDDASITTPATRMPALNARNSNP
HHHHCHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]