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The map label for this gene is argA [H]

Identifier: 92112845

GI number: 92112845

Start: 800410

End: 801723

Strand: Direct

Name: argA [H]

Synonym: Csal_0713

Alternate gene names: 92112845

Gene position: 800410-801723 (Clockwise)

Preceding gene: 92112844

Following gene: 92112847

Centisome position: 21.65

GC content: 68.34

Gene sequence:

>1314_bases
TTGAACACGCGCTTTCCCTTCGCCGACTGGTTTCGTAATTCGTCTCCGTATATCAATGCGCATCGCGGACGTACGTTCGT
GGTGCTCATCGAGGGCGAGGCCTTGGCATCCGAGCGATGGGAGCCGCTGCTGCAGGACCTGGCGCTGCTGCATACCCTGG
GCGTGCGCCTGGTGATGGTCTTTGGCATTCGTCCCCAGGTCGGCGAGGCGCTGAGCGCGGAGGGCATCGCGCCGCGCCGG
ATCGACGGTCGCTGGGTGGCCGACGGGGCGATCATGCGCCATGTCGAGCGTATCGCCGCCGAGCTGCGCCTCAAGATCGA
AGCGCGCCTGTCGCTGGGCCTGCCCAACACGCCCCTGCACGGTGTCGAGCTGACGGTGGTGTCCGGCAACCTGGTCACGG
CGAAACCGCTGGGCGTGCGCAACGGCGTGGATTTCCATCACAGCGGCGAGGTACGCCGCGTGCGCAGCCAGGCCATCGCC
GAGCTGCTGTCCCAGGAAACCCTGGTACTGCTGCCGCCGCTAGGCTATTCGAGTACCGGCGAGGTGTTCGATCTGGATGC
GGCCGATGTCGCCCAGCATGTCGCCATGGGGCTGGGCGCCGACAAGCTGATCCTGCTCGGCGACGCGGCGGGGCTGCACG
ACGCCAGCGGCTTGCTGCAGCGCCAATTGACGCCTCAGGAAGCGGAACCCCTGCGCCGTCAGGCACCGCCCGGCAGCGAG
CTGGCGCGACACCTGGGGGCGGCCTGCGAAGCGGCGCGTCACGGCGTGGCGCGCACGCACCTGCTTTCCTGGCACGATCG
CGATGCCTTGCTGGGTGAGCTGTTCACCCGGGACGGGGTCGGCACCATGATCACCCAGCACCGCTACGAGCAGTTGCGCC
GCGCGACGCTGGAAGACGTGGGCGGCCTGCTCGAACTGCTGCGCCCGCTCGAGGAGCGCGGCATGCTGGTGGCCCGCTCG
CGGGAACGCCTCGAGCATCAGGTCGACGATTACTGGGTCATCGAGCGCGACGGCATGATCATCGGCTGCGGTGCCCTGCA
TGCCTACCCCGACGCCTGCATGGGCGAGCTCGCCTGCGTCGCCGTGCATGGCGACTATCGGGGGGGCGCCCGGGGCGACC
TGCTGTTGGCCGAGATCGAGCGCGAATCGCGTCGGCGCGGTTTCACCGCCTTGTTCGCGCTCACCACCCACACCACGCAC
TGGTTCCTCGAGCGCGGCTTCCGGCTCGATGGCCTGGAGGCGCTGCCGCACATGCGCCGCGATTCCTACAATCACGCGCG
TCAATCCAAGGTGTTGCTCAAACCCCTCACCTGA

Upstream 100 bases:

>100_bases
AGTCGCCGCATCGCGAGGCGGGATCGGAGCTACCGGTCCCGCCTTTTCTATGCCTCTGATATAGTCATGATGTCTTTCCT
TCCTGCAGCTGGAGCGGGCC

Downstream 100 bases:

>100_bases
TCCTGTCTGCCCGCGCCGCTTCGCGCCCCGTCAATGGCGCGGGCGGCGTCTCGCCCGGCCATGACCTGTCGCTTTCCCTC
GACGGGTGTCTCCAATTGGA

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MNTRFPFADWFRNSSPYINAHRGRTFVVLIEGEALASERWEPLLQDLALLHTLGVRLVMVFGIRPQVGEALSAEGIAPRR
IDGRWVADGAIMRHVERIAAELRLKIEARLSLGLPNTPLHGVELTVVSGNLVTAKPLGVRNGVDFHHSGEVRRVRSQAIA
ELLSQETLVLLPPLGYSSTGEVFDLDAADVAQHVAMGLGADKLILLGDAAGLHDASGLLQRQLTPQEAEPLRRQAPPGSE
LARHLGAACEAARHGVARTHLLSWHDRDALLGELFTRDGVGTMITQHRYEQLRRATLEDVGGLLELLRPLEERGMLVARS
RERLEHQVDDYWVIERDGMIIGCGALHAYPDACMGELACVAVHGDYRGGARGDLLLAEIERESRRRGFTALFALTTHTTH
WFLERGFRLDGLEALPHMRRDSYNHARQSKVLLKPLT

Sequences:

>Translated_437_residues
MNTRFPFADWFRNSSPYINAHRGRTFVVLIEGEALASERWEPLLQDLALLHTLGVRLVMVFGIRPQVGEALSAEGIAPRR
IDGRWVADGAIMRHVERIAAELRLKIEARLSLGLPNTPLHGVELTVVSGNLVTAKPLGVRNGVDFHHSGEVRRVRSQAIA
ELLSQETLVLLPPLGYSSTGEVFDLDAADVAQHVAMGLGADKLILLGDAAGLHDASGLLQRQLTPQEAEPLRRQAPPGSE
LARHLGAACEAARHGVARTHLLSWHDRDALLGELFTRDGVGTMITQHRYEQLRRATLEDVGGLLELLRPLEERGMLVARS
RERLEHQVDDYWVIERDGMIIGCGALHAYPDACMGELACVAVHGDYRGGARGDLLLAEIERESRRRGFTALFALTTHTTH
WFLERGFRLDGLEALPHMRRDSYNHARQSKVLLKPLT
>Mature_437_residues
MNTRFPFADWFRNSSPYINAHRGRTFVVLIEGEALASERWEPLLQDLALLHTLGVRLVMVFGIRPQVGEALSAEGIAPRR
IDGRWVADGAIMRHVERIAAELRLKIEARLSLGLPNTPLHGVELTVVSGNLVTAKPLGVRNGVDFHHSGEVRRVRSQAIA
ELLSQETLVLLPPLGYSSTGEVFDLDAADVAQHVAMGLGADKLILLGDAAGLHDASGLLQRQLTPQEAEPLRRQAPPGSE
LARHLGAACEAARHGVARTHLLSWHDRDALLGELFTRDGVGTMITQHRYEQLRRATLEDVGGLLELLRPLEERGMLVARS
RERLEHQVDDYWVIERDGMIIGCGALHAYPDACMGELACVAVHGDYRGGARGDLLLAEIERESRRRGFTALFALTTHTTH
WFLERGFRLDGLEALPHMRRDSYNHARQSKVLLKPLT

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=434, Percent_Identity=44.0092165898618, Blast_Score=388, Evalue=1e-109,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 48452; Mature: 48452

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRFPFADWFRNSSPYINAHRGRTFVVLIEGEALASERWEPLLQDLALLHTLGVRLVMV
CCCCCCCHHHHCCCCCCEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGIRPQVGEALSAEGIAPRRIDGRWVADGAIMRHVERIAAELRLKIEARLSLGLPNTPLH
HCCCCHHCCHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCC
GVELTVVSGNLVTAKPLGVRNGVDFHHSGEVRRVRSQAIAELLSQETLVLLPPLGYSSTG
CEEEEEEECCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
EVFDLDAADVAQHVAMGLGADKLILLGDAAGLHDASGLLQRQLTPQEAEPLRRQAPPGSE
CEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHCCCCHHH
LARHLGAACEAARHGVARTHLLSWHDRDALLGELFTRDGVGTMITQHRYEQLRRATLEDV
HHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GGLLELLRPLEERGMLVARSRERLEHQVDDYWVIERDGMIIGCGALHAYPDACMGELACV
HHHHHHHHHHHHCCEEEEHHHHHHHHHCCCEEEEEECCEEEEECHHHCCCHHHHCCEEEE
AVHGDYRGGARGDLLLAEIERESRRRGFTALFALTTHTTHWFLERGFRLDGLEALPHMRR
EEECCCCCCCCCCEEHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHH
DSYNHARQSKVLLKPLT
CCHHHHHHCCCEECCCC
>Mature Secondary Structure
MNTRFPFADWFRNSSPYINAHRGRTFVVLIEGEALASERWEPLLQDLALLHTLGVRLVMV
CCCCCCCHHHHCCCCCCEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGIRPQVGEALSAEGIAPRRIDGRWVADGAIMRHVERIAAELRLKIEARLSLGLPNTPLH
HCCCCHHCCHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCC
GVELTVVSGNLVTAKPLGVRNGVDFHHSGEVRRVRSQAIAELLSQETLVLLPPLGYSSTG
CEEEEEEECCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
EVFDLDAADVAQHVAMGLGADKLILLGDAAGLHDASGLLQRQLTPQEAEPLRRQAPPGSE
CEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHCCCCHHH
LARHLGAACEAARHGVARTHLLSWHDRDALLGELFTRDGVGTMITQHRYEQLRRATLEDV
HHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GGLLELLRPLEERGMLVARSRERLEHQVDDYWVIERDGMIIGCGALHAYPDACMGELACV
HHHHHHHHHHHHCCEEEEHHHHHHHHHCCCEEEEEECCEEEEECHHHCCCHHHHCCEEEE
AVHGDYRGGARGDLLLAEIERESRRRGFTALFALTTHTTHWFLERGFRLDGLEALPHMRR
EEECCCCCCCCCCEEHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHH
DSYNHARQSKVLLKPLT
CCHHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]