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The map label for this gene is glnA [H]

Identifier: 92112811

GI number: 92112811

Start: 762215

End: 763576

Strand: Direct

Name: glnA [H]

Synonym: Csal_0679

Alternate gene names: 92112811

Gene position: 762215-763576 (Clockwise)

Preceding gene: 92112810

Following gene: 92112812

Centisome position: 20.62

GC content: 61.82

Gene sequence:

>1362_bases
ATGACCAACACGCTGGCTTTGGATGACCTGAAGACTAGGGTCGAGAGCGGTGAGATCGACACGGTGCTCGTATGCATTGT
CGACATGCAGGGGCGCCTGATGGGCAAGCGGCTGCATGCGCGCCACTTCGTGGACCATGGCTGGGAGGAGACTCACTGCT
GCAACTATCTATTGGCCACGGATCTCGAGATGGCAACGCCCGGTGGCTATGCAAGCACCTCCTGGCAGGCAGGCTACGGC
GACTACATCATGAAGCCGGATCTGGCCACGCTGCGCTGCGTGCCGTGGCTGGAGGGCACGGCCATGGTGCTGTGCGATCT
TCTTGATCATCGCACGCACGCGGAAGTCCCCCATGCGCCGCGTGCCATTCTCAAGCGACAGCTGGCGCGACTGGAGGCGA
TGGGGCTGGAGGCGATAATGGCCACCGAACTGGAGTTTTTCCTGTTCGAGAAAAGCCTCGACGAAATTCGCAAGGGAAGG
TTTCGCGACCTGCAGCCGATCAGCGGGTACAACGAGGACTATCATATCTTCCAGACCACCAAGGAAGAGCATGTGCTGCG
TCCGCTACGTAACCACCTGCATGCGGCGGGCATACCCGTGGAAGGCACCAAGGGGGAGGCCGGAGCGGGTCAGGAGGAGC
TCAACATACGTTGCGCGAAAGCACTCGATACGGCGGATTACCATACCATTGCCAAGCATGCGACCAAGGAGATCGCCTGG
CAGCAGGGGCGGGCGGTGACTTTCCTGTCGAAATGGCACCACGCCCATGCGGGGAGTTCCAGTCATATCCACCAGTCGCT
GTGGAAGCAGGGCCTGCCAGCCTTCCACGATGAGCGCGATGCGCTGGGCATGTCCGCTTTGATGAAACATTACCTGGCGG
GGTTGCTGAAATACGCGCCCGACTATACCTACTTCCTGGCTCCCTACCTCAATAGCTACAAGCGCTTCCAGAAGGGCACC
TTCGCACCCACGCGCACGGTCTGGTCGGTGGATAATCGTACCGCAGGGTTTCGCCTCTGCGCCGAAGGCACACGGGCGGT
GCGCATCGAGTGCCGCATCGGCGGCTCGGACCTGAACCCCTATCTGGCCATGGCCGGCCAGTTGGCCGCCGGCATCAAGG
GGATCGAAGAATGCCTGGCGCTGCCTCCTCCCGCCGAGGGCGATACCTACGAAGGGGGGAGTGGCCTGATACCACAGAAT
CTGCGCGATGCCATGGAGGCCCTGAGGGGCTCCACCATGCTGCGCGAGGCCATGGGGGAAGATGTGGTCGACCATTACGT
GCGAGCCGCCGAAGTGGAGCTCGAGGACTTCCAGCGGGTGGTCTCCGACTACGAGGTGGCACGCGGTTTCGAGCGGTGTT
GA

Upstream 100 bases:

>100_bases
GTCGGCCCCGTGCCCTGGCACCTGCCGGGGCACGCCGCTTGAAAGGGGACCGGCCGTGCGTCGGGCCTCGTCATGGTGAT
GGCTATTGGGAACCTCGGAA

Downstream 100 bases:

>100_bases
GGTCAGGTCCGCAAAACGGGAAATGGCAAACGGGAGGGGATGATGGGGCATATTCTGAGATGTATCTCGCCGATCGATGG
GTCGGTCTTCGCCGAGCGTG

Product: L-glutamine synthetase

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MTNTLALDDLKTRVESGEIDTVLVCIVDMQGRLMGKRLHARHFVDHGWEETHCCNYLLATDLEMATPGGYASTSWQAGYG
DYIMKPDLATLRCVPWLEGTAMVLCDLLDHRTHAEVPHAPRAILKRQLARLEAMGLEAIMATELEFFLFEKSLDEIRKGR
FRDLQPISGYNEDYHIFQTTKEEHVLRPLRNHLHAAGIPVEGTKGEAGAGQEELNIRCAKALDTADYHTIAKHATKEIAW
QQGRAVTFLSKWHHAHAGSSSHIHQSLWKQGLPAFHDERDALGMSALMKHYLAGLLKYAPDYTYFLAPYLNSYKRFQKGT
FAPTRTVWSVDNRTAGFRLCAEGTRAVRIECRIGGSDLNPYLAMAGQLAAGIKGIEECLALPPPAEGDTYEGGSGLIPQN
LRDAMEALRGSTMLREAMGEDVVDHYVRAAEVELEDFQRVVSDYEVARGFERC

Sequences:

>Translated_453_residues
MTNTLALDDLKTRVESGEIDTVLVCIVDMQGRLMGKRLHARHFVDHGWEETHCCNYLLATDLEMATPGGYASTSWQAGYG
DYIMKPDLATLRCVPWLEGTAMVLCDLLDHRTHAEVPHAPRAILKRQLARLEAMGLEAIMATELEFFLFEKSLDEIRKGR
FRDLQPISGYNEDYHIFQTTKEEHVLRPLRNHLHAAGIPVEGTKGEAGAGQEELNIRCAKALDTADYHTIAKHATKEIAW
QQGRAVTFLSKWHHAHAGSSSHIHQSLWKQGLPAFHDERDALGMSALMKHYLAGLLKYAPDYTYFLAPYLNSYKRFQKGT
FAPTRTVWSVDNRTAGFRLCAEGTRAVRIECRIGGSDLNPYLAMAGQLAAGIKGIEECLALPPPAEGDTYEGGSGLIPQN
LRDAMEALRGSTMLREAMGEDVVDHYVRAAEVELEDFQRVVSDYEVARGFERC
>Mature_452_residues
TNTLALDDLKTRVESGEIDTVLVCIVDMQGRLMGKRLHARHFVDHGWEETHCCNYLLATDLEMATPGGYASTSWQAGYGD
YIMKPDLATLRCVPWLEGTAMVLCDLLDHRTHAEVPHAPRAILKRQLARLEAMGLEAIMATELEFFLFEKSLDEIRKGRF
RDLQPISGYNEDYHIFQTTKEEHVLRPLRNHLHAAGIPVEGTKGEAGAGQEELNIRCAKALDTADYHTIAKHATKEIAWQ
QGRAVTFLSKWHHAHAGSSSHIHQSLWKQGLPAFHDERDALGMSALMKHYLAGLLKYAPDYTYFLAPYLNSYKRFQKGTF
APTRTVWSVDNRTAGFRLCAEGTRAVRIECRIGGSDLNPYLAMAGQLAAGIKGIEECLALPPPAEGDTYEGGSGLIPQNL
RDAMEALRGSTMLREAMGEDVVDHYVRAAEVELEDFQRVVSDYEVARGFERC

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=367, Percent_Identity=27.7929155313352, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI87081870, Length=445, Percent_Identity=29.438202247191, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790301, Length=325, Percent_Identity=28.3076923076923, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 50704; Mature: 50573

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTLALDDLKTRVESGEIDTVLVCIVDMQGRLMGKRLHARHFVDHGWEETHCCNYLLAT
CCCCEEHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
DLEMATPGGYASTSWQAGYGDYIMKPDLATLRCVPWLEGTAMVLCDLLDHRTHAEVPHAP
CCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCH
RAILKRQLARLEAMGLEAIMATELEFFLFEKSLDEIRKGRFRDLQPISGYNEDYHIFQTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECC
KEEHVLRPLRNHLHAAGIPVEGTKGEAGAGQEELNIRCAKALDTADYHTIAKHATKEIAW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHHHHCCHHHHHHHHHHHHHHHH
QQGRAVTFLSKWHHAHAGSSSHIHQSLWKQGLPAFHDERDALGMSALMKHYLAGLLKYAP
HCCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DYTYFLAPYLNSYKRFQKGTFAPTRTVWSVDNRTAGFRLCAEGTRAVRIECRIGGSDLNP
CCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEECCCEEEEEEEEECCCCCCH
YLAMAGQLAAGIKGIEECLALPPPAEGDTYEGGSGLIPQNLRDAMEALRGSTMLREAMGE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
DVVDHYVRAAEVELEDFQRVVSDYEVARGFERC
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNTLALDDLKTRVESGEIDTVLVCIVDMQGRLMGKRLHARHFVDHGWEETHCCNYLLAT
CCCEEHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
DLEMATPGGYASTSWQAGYGDYIMKPDLATLRCVPWLEGTAMVLCDLLDHRTHAEVPHAP
CCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCH
RAILKRQLARLEAMGLEAIMATELEFFLFEKSLDEIRKGRFRDLQPISGYNEDYHIFQTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECC
KEEHVLRPLRNHLHAAGIPVEGTKGEAGAGQEELNIRCAKALDTADYHTIAKHATKEIAW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHHHHCCHHHHHHHHHHHHHHHH
QQGRAVTFLSKWHHAHAGSSSHIHQSLWKQGLPAFHDERDALGMSALMKHYLAGLLKYAP
HCCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DYTYFLAPYLNSYKRFQKGTFAPTRTVWSVDNRTAGFRLCAEGTRAVRIECRIGGSDLNP
CCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEECCCEEEEEEEEECCCCCCH
YLAMAGQLAAGIKGIEECLALPPPAEGDTYEGGSGLIPQNLRDAMEALRGSTMLREAMGE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
DVVDHYVRAAEVELEDFQRVVSDYEVARGFERC
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7916055 [H]