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The map label for this gene is aroF [H]

Identifier: 92112721

GI number: 92112721

Start: 653719

End: 654789

Strand: Direct

Name: aroF [H]

Synonym: Csal_0588

Alternate gene names: 92112721

Gene position: 653719-654789 (Clockwise)

Preceding gene: 92112720

Following gene: 92112722

Centisome position: 17.68

GC content: 66.39

Gene sequence:

>1071_bases
ATGAACGCACCCTTGACGATGCCCCAACACCCCGACGCCACCGCGTCGCCCTCGCACCACCCATTGCCCACGCCGGGTGA
GCTCAAGCAGCGCATACCGCTGGCCCCGGCCCTCGAAGCCCGCATCGCGCAACAGCGCGACGCCGTCCAGGCGGTCCTCG
ACGGACGGGATGATCGCCTTCTGGTGGTCGTCGGCCCTTGCTCGATCCATGACCCGCAGGCGGCATTGGCGTATGCCGAG
AAGCTCAGCGAGCTTGCCGCGCGTCTCGACGATCGCCTGCTGATGGTGATGCGCGTCTACATCGAGAAGCCGCGTACCAC
CGTGGGCTGGAAAGGCCTGGCCTACGATCCCCATCTGGATGGCAGCGACGACATGGCACATGGCCTGGAAGTGTCGCGGC
GCCTGATGCGCGACATCGCCGCCCTGGGCATGCCCGTGGCCACCGAGTTGCTGCATCCGATGACGGCACCTTACCTCGAG
GATCTGCTCAGTTGGGTCGCCATCGGCGCACGTACCACCGAATCCCAGGTGCATCGCGAACTGGCCAGTGGCCTGCAGGC
CGCGGTGGGATTCAAGAACGGCACCGATGGCAGCGTCGACGTGGCCATCGCCGCGATGCAGTCGGCCGCGCATCCGCATC
GTCATTTCGCCATCGACGATGCCGGGCGTCCGGCGATGCGCGAGACCCGGGGCAATCCGCATACCCATGTCGTGCTGCGT
GGCGGTCACGGCAAGCCGAACTACGATGCGGCTTCGATGCGCGCCTGTCGGCTGGATCTGCAGGCGGCCGGTATCACGCC
GCGTTTGATGGTCGATTGCAGCCATGCCAATTCGCGCAAGGATCACCGCCGCCAGACCGAGGTCATGCTGGATGTGCTCG
AACAGCGCTTGGCCGGCAATCACGACGTGATCGGCGTCATGCTCGAAAGCTATTTGCACGAGGGCAAGCAGCCGCTCAAG
CTGGGCGCGTTGCGCTATGGCGTCTCCGTCACCGATGCCTGCCTGGGCTGGGAAGCGACCGAGCACTTGCTCACGCTGGC
CGCCGAGCGGCTGGGCGGTGTCGCGCGTTGA

Upstream 100 bases:

>100_bases
CCCCAGTTGCCACCTCCGACCGTGACACGCTGGGTGGCGTCCGCCGAACACGAAGTTCCGCTGTCCGCCCGTGACGGACA
GCCCAGCCAAGAGACTCGAC

Downstream 100 bases:

>100_bases
CCGTGTCCCGGCTTCATGGCGTTGTCACATGGCGCGGCTAGGGTAGTGCCTCACAGGAGCTTCGTGATGCGACCCCGAGC
GGTCGCCGGCCCGTGAGGAG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MNAPLTMPQHPDATASPSHHPLPTPGELKQRIPLAPALEARIAQQRDAVQAVLDGRDDRLLVVVGPCSIHDPQAALAYAE
KLSELAARLDDRLLMVMRVYIEKPRTTVGWKGLAYDPHLDGSDDMAHGLEVSRRLMRDIAALGMPVATELLHPMTAPYLE
DLLSWVAIGARTTESQVHRELASGLQAAVGFKNGTDGSVDVAIAAMQSAAHPHRHFAIDDAGRPAMRETRGNPHTHVVLR
GGHGKPNYDAASMRACRLDLQAAGITPRLMVDCSHANSRKDHRRQTEVMLDVLEQRLAGNHDVIGVMLESYLHEGKQPLK
LGALRYGVSVTDACLGWEATEHLLTLAAERLGGVAR

Sequences:

>Translated_356_residues
MNAPLTMPQHPDATASPSHHPLPTPGELKQRIPLAPALEARIAQQRDAVQAVLDGRDDRLLVVVGPCSIHDPQAALAYAE
KLSELAARLDDRLLMVMRVYIEKPRTTVGWKGLAYDPHLDGSDDMAHGLEVSRRLMRDIAALGMPVATELLHPMTAPYLE
DLLSWVAIGARTTESQVHRELASGLQAAVGFKNGTDGSVDVAIAAMQSAAHPHRHFAIDDAGRPAMRETRGNPHTHVVLR
GGHGKPNYDAASMRACRLDLQAAGITPRLMVDCSHANSRKDHRRQTEVMLDVLEQRLAGNHDVIGVMLESYLHEGKQPLK
LGALRYGVSVTDACLGWEATEHLLTLAAERLGGVAR
>Mature_356_residues
MNAPLTMPQHPDATASPSHHPLPTPGELKQRIPLAPALEARIAQQRDAVQAVLDGRDDRLLVVVGPCSIHDPQAALAYAE
KLSELAARLDDRLLMVMRVYIEKPRTTVGWKGLAYDPHLDGSDDMAHGLEVSRRLMRDIAALGMPVATELLHPMTAPYLE
DLLSWVAIGARTTESQVHRELASGLQAAVGFKNGTDGSVDVAIAAMQSAAHPHRHFAIDDAGRPAMRETRGNPHTHVVLR
GGHGKPNYDAASMRACRLDLQAAGITPRLMVDCSHANSRKDHRRQTEVMLDVLEQRLAGNHDVIGVMLESYLHEGKQPLK
LGALRYGVSVTDACLGWEATEHLLTLAAERLGGVAR

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=334, Percent_Identity=53.8922155688623, Blast_Score=367, Evalue=1e-103,
Organism=Escherichia coli, GI1786969, Length=321, Percent_Identity=51.0903426791277, Blast_Score=321, Evalue=4e-89,
Organism=Escherichia coli, GI1787996, Length=325, Percent_Identity=47.3846153846154, Blast_Score=309, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6320240, Length=339, Percent_Identity=45.7227138643068, Blast_Score=318, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6319726, Length=331, Percent_Identity=47.4320241691843, Blast_Score=306, Evalue=2e-84,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38709; Mature: 38709

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPLTMPQHPDATASPSHHPLPTPGELKQRIPLAPALEARIAQQRDAVQAVLDGRDDRL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
LVVVGPCSIHDPQAALAYAEKLSELAARLDDRLLMVMRVYIEKPRTTVGWKGLAYDPHLD
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GSDDMAHGLEVSRRLMRDIAALGMPVATELLHPMTAPYLEDLLSWVAIGARTTESQVHRE
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHH
LASGLQAAVGFKNGTDGSVDVAIAAMQSAAHPHRHFAIDDAGRPAMRETRGNPHTHVVLR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHCCCCCCEEEEEE
GGHGKPNYDAASMRACRLDLQAAGITPRLMVDCSHANSRKDHRRQTEVMLDVLEQRLAGN
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC
HDVIGVMLESYLHEGKQPLKLGALRYGVSVTDACLGWEATEHLLTLAAERLGGVAR
CCHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNAPLTMPQHPDATASPSHHPLPTPGELKQRIPLAPALEARIAQQRDAVQAVLDGRDDRL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
LVVVGPCSIHDPQAALAYAEKLSELAARLDDRLLMVMRVYIEKPRTTVGWKGLAYDPHLD
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GSDDMAHGLEVSRRLMRDIAALGMPVATELLHPMTAPYLEDLLSWVAIGARTTESQVHRE
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHH
LASGLQAAVGFKNGTDGSVDVAIAAMQSAAHPHRHFAIDDAGRPAMRETRGNPHTHVVLR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHCCCCCCEEEEEE
GGHGKPNYDAASMRACRLDLQAAGITPRLMVDCSHANSRKDHRRQTEVMLDVLEQRLAGN
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC
HDVIGVMLESYLHEGKQPLKLGALRYGVSVTDACLGWEATEHLLTLAAERLGGVAR
CCHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]