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The map label for this gene is fabZ [H]

Identifier: 92112707

GI number: 92112707

Start: 637309

End: 637752

Strand: Direct

Name: fabZ [H]

Synonym: Csal_0574

Alternate gene names: 92112707

Gene position: 637309-637752 (Clockwise)

Preceding gene: 92112706

Following gene: 92112708

Centisome position: 17.24

GC content: 57.21

Gene sequence:

>444_bases
ATGGTAATGGACATCAACGAGATCCGTGAGTATCTACCGCACCGTTATCCTTTCTTGCTGGTGGATCGTGTCACGGAGAT
CACGCTTGGCGAAACGATCGTCGCCTACAAGAATGTCAGTATCAACGAGCCGTTTTTCAATGGGCATTTCCCGCACCATC
CGATCATGCCCGGCGTGTTGATCATCGAGGCGATGGCCCAGGCGTGCGGTATCCTGGGGTTCAAGACCGTCAACAAGCTG
CCCGCCGACGGGTACGTCTATTACCTGGTGGGAAGCGACAACGTGCGTTTCAAGCGTCCGGTGATGCCGGGCGACCAGCT
GCGCCTGGAAGCCAATGTCATCAGGGGCAAGCGCGGTATCTGGAAATTCGCCTGCCGTGCTACGGTCGATGGCGAGCTGG
CCTGTGAAGCCGAGATCATCTGTGCCGAGAGGAAAGTCGCTTGA

Upstream 100 bases:

>100_bases
TGGGCCTGTATAATCCCCGCCTTATCCAGGCAGGCGGATCATTCCGCCCTCGTGTGCCTGCCAACGCGGCAGGCACTTCG
TTATTTCAGAGGTTGTATCG

Downstream 100 bases:

>100_bases
TTCATCCCACCGCCCTCGTCGACCCCAGTGCGCGTGTGTCCGATGACGTCGACATCGGCCCGTTCTGCGTGATCGGCCCC
GAGGTGGAAATCGGGGACGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MVMDINEIREYLPHRYPFLLVDRVTEITLGETIVAYKNVSINEPFFNGHFPHHPIMPGVLIIEAMAQACGILGFKTVNKL
PADGYVYYLVGSDNVRFKRPVMPGDQLRLEANVIRGKRGIWKFACRATVDGELACEAEIICAERKVA

Sequences:

>Translated_147_residues
MVMDINEIREYLPHRYPFLLVDRVTEITLGETIVAYKNVSINEPFFNGHFPHHPIMPGVLIIEAMAQACGILGFKTVNKL
PADGYVYYLVGSDNVRFKRPVMPGDQLRLEANVIRGKRGIWKFACRATVDGELACEAEIICAERKVA
>Mature_147_residues
MVMDINEIREYLPHRYPFLLVDRVTEITLGETIVAYKNVSINEPFFNGHFPHHPIMPGVLIIEAMAQACGILGFKTVNKL
PADGYVYYLVGSDNVRFKRPVMPGDQLRLEANVIRGKRGIWKFACRATVDGELACEAEIICAERKVA

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=146, Percent_Identity=55.4794520547945, Blast_Score=167, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16594; Mature: 16594

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMDINEIREYLPHRYPFLLVDRVTEITLGETIVAYKNVSINEPFFNGHFPHHPIMPGVL
CCCCHHHHHHHCCCCCCEEEEEHHHHEECCCEEEEEECCCCCCCCCCCCCCCCCCCCHHH
IIEAMAQACGILGFKTVNKLPADGYVYYLVGSDNVRFKRPVMPGDQLRLEANVIRGKRGI
HHHHHHHHHCCCCHHHHCCCCCCCEEEEEECCCCCEEECCCCCCCCEEEEEEEECCCCCC
WKFACRATVDGELACEAEIICAERKVA
EEEEEEECCCCCEEECEEEEECCCCCC
>Mature Secondary Structure
MVMDINEIREYLPHRYPFLLVDRVTEITLGETIVAYKNVSINEPFFNGHFPHHPIMPGVL
CCCCHHHHHHHCCCCCCEEEEEHHHHEECCCEEEEEECCCCCCCCCCCCCCCCCCCCHHH
IIEAMAQACGILGFKTVNKLPADGYVYYLVGSDNVRFKRPVMPGDQLRLEANVIRGKRGI
HHHHHHHHHCCCCHHHHCCCCCCCEEEEEECCCCCEEECCCCCCCCEEEEEEEECCCCCC
WKFACRATVDGELACEAEIICAERKVA
EEEEEEECCCCCEEECEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA