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The map label for this gene is yaeL [C]

Identifier: 92112703

GI number: 92112703

Start: 631621

End: 632976

Strand: Direct

Name: yaeL [C]

Synonym: Csal_0570

Alternate gene names: 92112703

Gene position: 631621-632976 (Clockwise)

Preceding gene: 92112702

Following gene: 92112704

Centisome position: 17.09

GC content: 66.74

Gene sequence:

>1356_bases
ATGGGCGTGATTGAGAACCTGCTGGCGGTCATCGTGGTTCTGGGATTGTTGATCACCTTCCACGAGTTCGGCCATTTCTG
GGTCGCGCGGCGTTGCGGCGTCAAGGTGCTGCGTTTCTCGGTGGGGTTCGGCAAGCCGTTATGGTCGCGGTTCGATCGCC
ACGGCACGGAATTCGCCGTGGCCGCGATTCCGCTCGGCGGCTATGTCAAGATGCTCGATGAGCGCGAGGGGCCGGTGGCG
CCGGAAGAGCAGGCGCATGCCTTCAACCGCAAGAGCGTATGGGCCAGGATCGCCATCGTCTCGGCCGGCCCGCTGGCAAA
TTTTCTGCTCGCCTTCGTCGCTTACTGGGCCCTGTTCATCTACGGCACGGCCACGGTGGCGCCGGTGATCGGCGATGTCA
CGCCGGATTCGCCGGCCGCTCAGGGCGGTTTGCAGCGCGGCCAGGAAATCGTGGCCGTGCAGGGCGAGCCGACCCCGTCG
TGGGGCGAGGTCAACCTCAAGCTGGTGGCGGCCATCGGCGCCGATGGCACCCTCGACGTGACCACGCGGACGTCAGAGGG
CGCCACGCCGACGCAGCATCGGGTGCCGGTCAACGACTGGCTGGTACGCCAGAATCCGCCTCAGCCGCTGGCATCGCTGG
GCGTGACGCCCTGGCGTCCCGAGCTGCCGGCGGTCCTCGGTGAGGTGCTGGATGACGGTCGCGCGCATCAGGCGGGGCTG
CAACGCGGGGATCGTATCGTCAGTGTCGATGGTGTGGCCGTCGACGACTGGATGGCGTTCGTCGAGCGTGTGCGCGCCAA
TCCGGAGACGCCCTTGACCCTGCAGGTGACGCGCGATGGCGAGCGCCGCGAGATCACGCTGACGCCCGCCGTGCGCGAAC
AGGAAGATGGCTCGACCATCGGTTATATCGGGGCCGGCGTGCAGCCGTCCGAATGGCCCGAGCGCTACCGTCGCGAGATT
CGCTACGGCCCACTGGACGCCGTCGGCGAGGCGGTCGCCAAGACAGGGGAGATGAGCCTGCTCACGCTGGACTCGATCCG
CAAGATGCTGGTGGGGCTGATTTCCCCCTCCAACCTCTCGGGGCCCGTGACCATCGCCCGCATTGCGGGGGATTCCGCAC
GCGATGGCGTGGAGAGCTTCATCAGCTTCCTGGCGTATCTGTCGATCAGCCTGGGGGTGCTCAATCTGTTGCCGATCCCC
GTGCTCGATGGCGGGCATCTGGTCTACTACATCATCGAGGCTGTGCGCGGGCGCCCGGTGCCCGAGGCCGTGCAGGCCTT
CGGTCTGCGTGTGGGCATCGCGCTGGTGGGCTCGTTGATGCTGATGGCGTTGTACTTCGACCTGATGCGTCTGTAG

Upstream 100 bases:

>100_bases
GCGGCTGACGCCACCGCGCGGCGTGTCGCCGAGCGCGAATTGAGCCGGTTCACGTCATGATGTCAGGGCGGTGGCCCGCG
CGAGGAAGGAGGACGGTCCC

Downstream 100 bases:

>100_bases
CCCTCATTGCGGGGCGGCCCTCGGCCGGGCTTTAATGTGGGCCGACGATGGCCTGGGTAAGCGGTCGTTGACCGCAAGGA
TGAGCGACCCGGGGGAACGT

Product: peptidase M50 membrane-associated zinc metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MGVIENLLAVIVVLGLLITFHEFGHFWVARRCGVKVLRFSVGFGKPLWSRFDRHGTEFAVAAIPLGGYVKMLDEREGPVA
PEEQAHAFNRKSVWARIAIVSAGPLANFLLAFVAYWALFIYGTATVAPVIGDVTPDSPAAQGGLQRGQEIVAVQGEPTPS
WGEVNLKLVAAIGADGTLDVTTRTSEGATPTQHRVPVNDWLVRQNPPQPLASLGVTPWRPELPAVLGEVLDDGRAHQAGL
QRGDRIVSVDGVAVDDWMAFVERVRANPETPLTLQVTRDGERREITLTPAVREQEDGSTIGYIGAGVQPSEWPERYRREI
RYGPLDAVGEAVAKTGEMSLLTLDSIRKMLVGLISPSNLSGPVTIARIAGDSARDGVESFISFLAYLSISLGVLNLLPIP
VLDGGHLVYYIIEAVRGRPVPEAVQAFGLRVGIALVGSLMLMALYFDLMRL

Sequences:

>Translated_451_residues
MGVIENLLAVIVVLGLLITFHEFGHFWVARRCGVKVLRFSVGFGKPLWSRFDRHGTEFAVAAIPLGGYVKMLDEREGPVA
PEEQAHAFNRKSVWARIAIVSAGPLANFLLAFVAYWALFIYGTATVAPVIGDVTPDSPAAQGGLQRGQEIVAVQGEPTPS
WGEVNLKLVAAIGADGTLDVTTRTSEGATPTQHRVPVNDWLVRQNPPQPLASLGVTPWRPELPAVLGEVLDDGRAHQAGL
QRGDRIVSVDGVAVDDWMAFVERVRANPETPLTLQVTRDGERREITLTPAVREQEDGSTIGYIGAGVQPSEWPERYRREI
RYGPLDAVGEAVAKTGEMSLLTLDSIRKMLVGLISPSNLSGPVTIARIAGDSARDGVESFISFLAYLSISLGVLNLLPIP
VLDGGHLVYYIIEAVRGRPVPEAVQAFGLRVGIALVGSLMLMALYFDLMRL
>Mature_450_residues
GVIENLLAVIVVLGLLITFHEFGHFWVARRCGVKVLRFSVGFGKPLWSRFDRHGTEFAVAAIPLGGYVKMLDEREGPVAP
EEQAHAFNRKSVWARIAIVSAGPLANFLLAFVAYWALFIYGTATVAPVIGDVTPDSPAAQGGLQRGQEIVAVQGEPTPSW
GEVNLKLVAAIGADGTLDVTTRTSEGATPTQHRVPVNDWLVRQNPPQPLASLGVTPWRPELPAVLGEVLDDGRAHQAGLQ
RGDRIVSVDGVAVDDWMAFVERVRANPETPLTLQVTRDGERREITLTPAVREQEDGSTIGYIGAGVQPSEWPERYRREIR
YGPLDAVGEAVAKTGEMSLLTLDSIRKMLVGLISPSNLSGPVTIARIAGDSARDGVESFISFLAYLSISLGVLNLLPIPV
LDGGHLVYYIIEAVRGRPVPEAVQAFGLRVGIALVGSLMLMALYFDLMRL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=446, Percent_Identity=45.7399103139013, Blast_Score=374, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 48776; Mature: 48645

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVIENLLAVIVVLGLLITFHEFGHFWVARRCGVKVLRFSVGFGKPLWSRFDRHGTEFAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHCCCCEEEE
AAIPLGGYVKMLDEREGPVAPEEQAHAFNRKSVWARIAIVSAGPLANFLLAFVAYWALFI
EEECCCHHHHHHHCCCCCCCCHHHHHHCCCHHHEEEEEEEECCHHHHHHHHHHHHHHHHH
YGTATVAPVIGDVTPDSPAAQGGLQRGQEIVAVQGEPTPSWGEVNLKLVAAIGADGTLDV
HHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEEECCCCEEEE
TTRTSEGATPTQHRVPVNDWLVRQNPPQPLASLGVTPWRPELPAVLGEVLDDGRAHQAGL
EECCCCCCCCCCCCCCHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHH
QRGDRIVSVDGVAVDDWMAFVERVRANPETPLTLQVTRDGERREITLTPAVREQEDGSTI
HCCCEEEEECCEEHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCEE
GYIGAGVQPSEWPERYRREIRYGPLDAVGEAVAKTGEMSLLTLDSIRKMLVGLISPSNLS
EEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCC
GPVTIARIAGDSARDGVESFISFLAYLSISLGVLNLLPIPVLDGGHLVYYIIEAVRGRPV
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCC
PEAVQAFGLRVGIALVGSLMLMALYFDLMRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GVIENLLAVIVVLGLLITFHEFGHFWVARRCGVKVLRFSVGFGKPLWSRFDRHGTEFAV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHCCCCEEEE
AAIPLGGYVKMLDEREGPVAPEEQAHAFNRKSVWARIAIVSAGPLANFLLAFVAYWALFI
EEECCCHHHHHHHCCCCCCCCHHHHHHCCCHHHEEEEEEEECCHHHHHHHHHHHHHHHHH
YGTATVAPVIGDVTPDSPAAQGGLQRGQEIVAVQGEPTPSWGEVNLKLVAAIGADGTLDV
HHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEEECCCCEEEE
TTRTSEGATPTQHRVPVNDWLVRQNPPQPLASLGVTPWRPELPAVLGEVLDDGRAHQAGL
EECCCCCCCCCCCCCCHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHH
QRGDRIVSVDGVAVDDWMAFVERVRANPETPLTLQVTRDGERREITLTPAVREQEDGSTI
HCCCEEEEECCEEHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCEE
GYIGAGVQPSEWPERYRREIRYGPLDAVGEAVAKTGEMSLLTLDSIRKMLVGLISPSNLS
EEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCC
GPVTIARIAGDSARDGVESFISFLAYLSISLGVLNLLPIPVLDGGHLVYYIIEAVRGRPV
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCC
PEAVQAFGLRVGIALVGSLMLMALYFDLMRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]