Click here to switch to the map view.

The map label for this gene is yocR [H]

Identifier: 92112533

GI number: 92112533

Start: 446355

End: 447695

Strand: Direct

Name: yocR [H]

Synonym: Csal_0400

Alternate gene names: 92112533

Gene position: 446355-447695 (Clockwise)

Preceding gene: 92112530

Following gene: 92112534

Centisome position: 12.07

GC content: 64.06

Gene sequence:

>1341_bases
ATGAGTGAAACGCTGGAACGCTGGGGGTCGCGACGTGCCTTCATTCTCGCGGTGACCGGGGCGGCCGTGGGGCTGGGCAA
CATCTGGCGCTTTCCCTACATGACGGGCGAAAACGGCGGAGCGGCCTTCTTGCTGCTGTACGTGGCGTTCGTGATGGTGC
TGGGGCTGCCGATCATGATGGCCGAGATCCTGGTGGGGCGTGCCGGTCGTCGCGGGCCGATGCAATCGTTGGCGCACCTG
GCGCGTCACGCGGGCGTGTCGCCGCATTGGCGCTGGCTGGGGCTGTTCGGCGCCATAACGGTGTTCTTCATCCTGTCGTT
CTATTCGGTGGTCTCGGGGTGGTCGATCGAGTATCTGATCGAGTCGGTCAACGGCAACTTCAGTGGCCGGACGCCGGCTG
AAATCGGGGCCAGTTTCGAGGCCTTCCTCGCCGACCCGCTGCGCATGACGTTCAATCACACGCTCTTCATGCTGCTGACC
ATGTCGGTGGTCGCGGCGGGCATTTCCGGTGGCCTGGAGCGACTCAACAACCTGTTGATGCCGCTTCTTTACATCCTGCT
GGTGGTATTGGCCGGTTATGCCGTGACGACCGATGGCTTCGGCACCGCCATGACATGGCTGTTCGCGCCCGACCTCGATG
CCATCACCCTGAGCGTGGTGCTCAATGCCATGGGACATGCATTCTTCACCCTGGCGGTGGGCGCCTGCGCGTTGATGGCC
TATGGCGCCTACATGCCCGACCATCAGAGCCTGCCACGTGCAGTGATGGCGGTGGCCGTGCTGGATATCACCGTGGCGCT
GCTGGCGGGGATCGCGATCTTCTCGGTGGTCTTCTCGCAGGGCATGGATCCCGGCGAGGGACCGGGGTTGATGTTCGTGA
CCCTGCCGATCGCCTTTTCCGACCTGCCGGGCGGGTCGTTATGGCTGGGCGTCTTCTTCCTGCTGTTGCTGCTGGCGACC
TGGACCTCGTCGATCAACCTGGCCGAGCCGATGGTGGCGATCTTCACCGATGCCGGCCTCAAGCGGGGCAAGGCGACGGC
GCTGATCGGCACCCTGGTCTGGATGGTCGGCTTGCTGTCGGTGTTTTCGTTCTCGACCCTGTCGGAGGTGACATGGGTTG
CGGGCATGAACTTCTTCGAGCTGGTGACCACGGTGCCGCCCGAGATTTTCCTGCCCATCGGCGGCTTGCTGATCGCGATC
TTCGCCGCCTGGGTCATGCCGGCCAGCGAAGCGATGCGAGCGCTGGATGCCGGGCCCGGCGGTTTCCGGTTATGGCGCGG
CGTGGTGCGCTACGTGTCGATTCCACTGCTGGTGATCGTACTGCTCTCGGCGCTTTGGTGA

Upstream 100 bases:

>100_bases
CTTTCAATGTTGCGGCAATTGGCCGCCATCCCCGCGCCTGCTAGGCTTGGCGCTTTCGGCGCGGGTGCGCCATGAGTCGT
GCGACGAAGGATACAACGCC

Downstream 100 bases:

>100_bases
GGGGAGCCGCCGCAAGGCATGCCACCCTATTGGCAACGACAACAGGACAAGGAGACAGCTGATGACACTGCGGACGTTTC
AGGGAATGACGCCGCGCCTG

Product: sodium:neurotransmitter symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSETLERWGSRRAFILAVTGAAVGLGNIWRFPYMTGENGGAAFLLLYVAFVMVLGLPIMMAEILVGRAGRRGPMQSLAHL
ARHAGVSPHWRWLGLFGAITVFFILSFYSVVSGWSIEYLIESVNGNFSGRTPAEIGASFEAFLADPLRMTFNHTLFMLLT
MSVVAAGISGGLERLNNLLMPLLYILLVVLAGYAVTTDGFGTAMTWLFAPDLDAITLSVVLNAMGHAFFTLAVGACALMA
YGAYMPDHQSLPRAVMAVAVLDITVALLAGIAIFSVVFSQGMDPGEGPGLMFVTLPIAFSDLPGGSLWLGVFFLLLLLAT
WTSSINLAEPMVAIFTDAGLKRGKATALIGTLVWMVGLLSVFSFSTLSEVTWVAGMNFFELVTTVPPEIFLPIGGLLIAI
FAAWVMPASEAMRALDAGPGGFRLWRGVVRYVSIPLLVIVLLSALW

Sequences:

>Translated_446_residues
MSETLERWGSRRAFILAVTGAAVGLGNIWRFPYMTGENGGAAFLLLYVAFVMVLGLPIMMAEILVGRAGRRGPMQSLAHL
ARHAGVSPHWRWLGLFGAITVFFILSFYSVVSGWSIEYLIESVNGNFSGRTPAEIGASFEAFLADPLRMTFNHTLFMLLT
MSVVAAGISGGLERLNNLLMPLLYILLVVLAGYAVTTDGFGTAMTWLFAPDLDAITLSVVLNAMGHAFFTLAVGACALMA
YGAYMPDHQSLPRAVMAVAVLDITVALLAGIAIFSVVFSQGMDPGEGPGLMFVTLPIAFSDLPGGSLWLGVFFLLLLLAT
WTSSINLAEPMVAIFTDAGLKRGKATALIGTLVWMVGLLSVFSFSTLSEVTWVAGMNFFELVTTVPPEIFLPIGGLLIAI
FAAWVMPASEAMRALDAGPGGFRLWRGVVRYVSIPLLVIVLLSALW
>Mature_445_residues
SETLERWGSRRAFILAVTGAAVGLGNIWRFPYMTGENGGAAFLLLYVAFVMVLGLPIMMAEILVGRAGRRGPMQSLAHLA
RHAGVSPHWRWLGLFGAITVFFILSFYSVVSGWSIEYLIESVNGNFSGRTPAEIGASFEAFLADPLRMTFNHTLFMLLTM
SVVAAGISGGLERLNNLLMPLLYILLVVLAGYAVTTDGFGTAMTWLFAPDLDAITLSVVLNAMGHAFFTLAVGACALMAY
GAYMPDHQSLPRAVMAVAVLDITVALLAGIAIFSVVFSQGMDPGEGPGLMFVTLPIAFSDLPGGSLWLGVFFLLLLLATW
TSSINLAEPMVAIFTDAGLKRGKATALIGTLVWMVGLLSVFSFSTLSEVTWVAGMNFFELVTTVPPEIFLPIGGLLIAIF
AAWVMPASEAMRALDAGPGGFRLWRGVVRYVSIPLLVIVLLSALW

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=382, Percent_Identity=26.1780104712042, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI188528618, Length=373, Percent_Identity=25.201072386059, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI4507043, Length=359, Percent_Identity=24.7910863509749, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI171184408, Length=407, Percent_Identity=24.5700245700246, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI171184406, Length=407, Percent_Identity=24.5700245700246, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI171184404, Length=407, Percent_Identity=24.5700245700246, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI7657587, Length=379, Percent_Identity=25.3298153034301, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI289191351, Length=400, Percent_Identity=24.75, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI4557046, Length=400, Percent_Identity=24.75, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI289191377, Length=401, Percent_Identity=24.6882793017456, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI197276623, Length=416, Percent_Identity=24.2788461538462, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI54607094, Length=416, Percent_Identity=24.2788461538462, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI194018524, Length=309, Percent_Identity=26.8608414239482, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI11181770, Length=303, Percent_Identity=25.0825082508251, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI92859670, Length=454, Percent_Identity=23.3480176211454, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI58219014, Length=305, Percent_Identity=25.5737704918033, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI4507041, Length=370, Percent_Identity=25.1351351351351, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI33354281, Length=301, Percent_Identity=24.2524916943522, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI21361693, Length=115, Percent_Identity=38.2608695652174, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI134304856, Length=347, Percent_Identity=25.9365994236311, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI51468073, Length=329, Percent_Identity=23.1003039513678, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI12408638, Length=292, Percent_Identity=25.6849315068493, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI67782317, Length=370, Percent_Identity=23.5135135135135, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI67782313, Length=370, Percent_Identity=23.5135135135135, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI67782315, Length=370, Percent_Identity=23.5135135135135, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI5032097, Length=117, Percent_Identity=35.8974358974359, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI218563756, Length=117, Percent_Identity=35.8974358974359, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI197276625, Length=134, Percent_Identity=33.5820895522388, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI6005715, Length=129, Percent_Identity=32.5581395348837, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI133952791, Length=448, Percent_Identity=24.3303571428571, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25146584, Length=408, Percent_Identity=22.7941176470588, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71995588, Length=385, Percent_Identity=23.6363636363636, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17555248, Length=121, Percent_Identity=34.7107438016529, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17554804, Length=486, Percent_Identity=23.4567901234568, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17542050, Length=155, Percent_Identity=32.9032258064516, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17535731, Length=130, Percent_Identity=33.0769230769231, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI17136952, Length=387, Percent_Identity=25.5813953488372, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281364394, Length=387, Percent_Identity=25.5813953488372, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28574704, Length=387, Percent_Identity=25.5813953488372, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17136950, Length=387, Percent_Identity=25.5813953488372, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28574702, Length=387, Percent_Identity=25.5813953488372, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24654186, Length=532, Percent_Identity=23.8721804511278, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24762620, Length=381, Percent_Identity=25.9842519685039, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI221329674, Length=397, Percent_Identity=24.6851385390428, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24639514, Length=397, Percent_Identity=24.6851385390428, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI45551183, Length=424, Percent_Identity=24.2924528301887, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45550877, Length=424, Percent_Identity=24.2924528301887, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24639516, Length=302, Percent_Identity=26.158940397351, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24655079, Length=439, Percent_Identity=22.3234624145786, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24652942, Length=386, Percent_Identity=23.0569948186528, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI45551088, Length=386, Percent_Identity=22.7979274611399, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI281364136, Length=466, Percent_Identity=24.4635193133047, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24661428, Length=388, Percent_Identity=22.9381443298969, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281365034, Length=426, Percent_Identity=23.2394366197183, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24582567, Length=353, Percent_Identity=22.6628895184136, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19921936, Length=414, Percent_Identity=22.2222222222222, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281363702, Length=369, Percent_Identity=23.3062330623306, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281363700, Length=331, Percent_Identity=23.5649546827795, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639853, Length=430, Percent_Identity=24.1860465116279, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI19921352, Length=120, Percent_Identity=30.8333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584353, Length=120, Percent_Identity=30.8333333333333, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 47835; Mature: 47704

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETLERWGSRRAFILAVTGAAVGLGNIWRFPYMTGENGGAAFLLLYVAFVMVLGLPIMM
CCCHHHHHCCCCEEEEEECCHHHCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
AEILVGRAGRRGPMQSLAHLARHAGVSPHWRWLGLFGAITVFFILSFYSVVSGWSIEYLI
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ESVNGNFSGRTPAEIGASFEAFLADPLRMTFNHTLFMLLTMSVVAAGISGGLERLNNLLM
HHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLLYILLVVLAGYAVTTDGFGTAMTWLFAPDLDAITLSVVLNAMGHAFFTLAVGACALMA
HHHHHHHHHHCCCCEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGAYMPDHQSLPRAVMAVAVLDITVALLAGIAIFSVVFSQGMDPGEGPGLMFVTLPIAFS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECEEEC
DLPGGSLWLGVFFLLLLLATWTSSINLAEPMVAIFTDAGLKRGKATALIGTLVWMVGLLS
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VFSFSTLSEVTWVAGMNFFELVTTVPPEIFLPIGGLLIAIFAAWVMPASEAMRALDAGPG
HHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
GFRLWRGVVRYVSIPLLVIVLLSALW
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SETLERWGSRRAFILAVTGAAVGLGNIWRFPYMTGENGGAAFLLLYVAFVMVLGLPIMM
CCHHHHHCCCCEEEEEECCHHHCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
AEILVGRAGRRGPMQSLAHLARHAGVSPHWRWLGLFGAITVFFILSFYSVVSGWSIEYLI
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ESVNGNFSGRTPAEIGASFEAFLADPLRMTFNHTLFMLLTMSVVAAGISGGLERLNNLLM
HHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLLYILLVVLAGYAVTTDGFGTAMTWLFAPDLDAITLSVVLNAMGHAFFTLAVGACALMA
HHHHHHHHHHCCCCEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGAYMPDHQSLPRAVMAVAVLDITVALLAGIAIFSVVFSQGMDPGEGPGLMFVTLPIAFS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECEEEC
DLPGGSLWLGVFFLLLLLATWTSSINLAEPMVAIFTDAGLKRGKATALIGTLVWMVGLLS
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VFSFSTLSEVTWVAGMNFFELVTTVPPEIFLPIGGLLIAIFAAWVMPASEAMRALDAGPG
HHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
GFRLWRGVVRYVSIPLLVIVLLSALW
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]