| Definition | Chromohalobacter salexigens DSM 3043 chromosome, complete genome. |
|---|---|
| Accession | NC_007963 |
| Length | 3,696,649 |
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The map label for this gene is nrdE [H]
Identifier: 92112512
GI number: 92112512
Start: 422281
End: 424452
Strand: Direct
Name: nrdE [H]
Synonym: Csal_0379
Alternate gene names: 92112512
Gene position: 422281-424452 (Clockwise)
Preceding gene: 92112511
Following gene: 92112513
Centisome position: 11.42
GC content: 61.83
Gene sequence:
>2172_bases TTGGATGACACCGTGGAACTCACCGAGAAGACACCCGCCGTCGAGGCGAGCCGGGCGACGCAGACGCTGGATTACCATGC GCTCAATGCGATGCTCAATCTCTACGACGATCAGGGCCGCCTGCAGCTGGACGCGGACCGTGAAGCGTCGCGCCAGTATT TCCTGCAGCACGTGAATCAGAACACCGTGTTCTTCCACACGCTGGCGGAAAAGCTCGAGTACCTGGTCGCGGAGAACTAT TACGAGCAGGAAGTGCTCGATCAGTACGACTTTCCTTTCATCAAGTCGCTGTTCGAGCGCGCCTATGCCGTGAAGTTCCG CTTCCAGAGCTTCCTCGGCGCCTTCAAGTATTACACCAGCTACACCCTCAAGACCTTCGATGGTCGGCGCTATCTGGAGC GCTTCGAGGACCGCGTCTGCATGGTCGCGCTGACCCTGGCGCAGGGCGATGAGGCGCTGGCCCGGCAGCTGGTGGATGAG ATCATCCACGGGCGTTTCCAGCCGGCCACGCCGACGTTTCTCAATTGCGGCAAGAAGCAGCGCGGCGAGCTGGTGTCCTG CTTTCTGCTTCGCATCGAGGACAACATGGAGTCCATCGGGCGCTCCATCAATTCGGCGTTGCAGCTCTCCAAGCGGGGTG GCGGCGTGGCGTTCCTGCTCAGCAACATCCGCGAGGCGGGAGCGCCGATCAAGCATATCGAGAACCAGTCCTCGGGCATC ATTCCGATCATGAAGATGCTCGAAGACGCCTTCTCCTACGCCAACCAGCTGGGCGCGCGTCAGGGGGCCGGCGCGGTGTA TCTCAACGCGCACCACCCGGATATCCTGCGTTTCCTCGACACCAAGCGCGAGAACGCCGACGAGAAGATCCGCATCAAGA CGCTGTCGCTGGGCGTGGTGATTCCGGACATCACCTTCGAGCTGGCCAAGCGCAACGAGCCGATGTACCTGTTCTCGCCC TACGACGTCGAGAACGTCTACGGCAAGCCGTTCGGCGACATCAGCGTCACCGAGAAGTACTACGAGATGGTCGACGACGC GCGTATCCGCAAGACCAAGATCAACGCGCGGGAGCTGTTCCAGACGCTGGCGGAGGTCCAGTTCGAGTCGGGCTATCCGT ACGTGATGTTCGAGGACACGGTGAACCGTGCCAACCCGATCGCCGGGCGCATCAACATGAGCAACCTGTGCTCGGAGATC CTCCAGGTCAACACGCCGTCCGATTACGAGGCGGACCTGGGCTACGAGCGCATCGGCGAGGACATTTCCTGCAACCTCGG CTCGCTGAACATCGCCAAGACCATGGACTCCTCCGATTTCGGGGCCACGGTCGAGACCGCCATTCGTGGGCTGACCGCGG TGTCCGAGATGAGCGACATCCGCTCGGTGCCGTCGATCGCCGAGGCCAACAAGCAGTCGCATGCGATCGGTCTGGGACAG ATGAACCTGCATGGCTACCTGGCCCGCGAACACATTCACTACGGTAGCGAGGAAGGGCTGGACTTCACCAACCTGTACTT CTACACCGTGACCTACCATGCGCTGCGTGCCTCCAACCGTCTGGCGATCGAGCGCGGTCGCGCCTTTGCCGGGTTCGAGG CGTCGGATTACGCCAGCGGCGTCTACTTCGACAAGTACACCGAGCAGGCGTGGGGCCCGCGTACCGCGCGTGTTCGCGAG CTGTTCGACAAGGCTGGCATCCATGTGCCGACCCAGGAGGACTGGCGCGAGCTCAAGGCCTCGGTCATGGCGCATGGGCT CTTCAACCGCAACCTCCAGGCGGTGCCGCCGACCGGTTCGATCTCCTATATCAACCATTCGACGTCGAGCATCCATCCGG TGGTGTCGAAGATCGAGATCCGCAAGGAAGGCAAGCTGGGACGCGTCTATTACCCGGCGCCGTATCTCAACGACGACAAC CAGGACTATTACCAGGACGCCTACGAGATCGGCCCCGAGAAGATCATCGACACCTATGCCGAGGCGACGCAGCACGTCGA CCAGGGCCTGTCGCTGACGCTGTTCTTCCGTGATACCGCGACCACGCGCGACATCAATCGGGCGCAGATCTACGCCTGGC GCAAGGGCATCAAGACGCTCTACTACGTGCGTCTGCGCCAGGCCGCACTGGAAGGCACGGAAGTCGAGGGCTGCGTTTCC TGCACCCTGTGA
Upstream 100 bases:
>100_bases CACAAGTGCGAGGTGCCGTTGCTGCACCGCTTCGAATTGATGGGAACGCCCGAGGATGTCGCCAAGGTGCGCGCGTGCCT GGCGATGGAGATGACAGATG
Downstream 100 bases:
>100_bases CGGCAGGCGACGTGCCCGAGCCATAGACACTTCCATCACGATCATCGGCGAGGCGTGGCGACCGGCCAGCCTCGCCGTCG GCAATGAGAGAACCTCCATG
Product: ribonucleoside-diphosphate reductase class Ib alpha subunit
Products: NA
Alternate protein names: Ribonucleotide reductase R1 subunit [H]
Number of amino acids: Translated: 723; Mature: 723
Protein sequence:
>723_residues MDDTVELTEKTPAVEASRATQTLDYHALNAMLNLYDDQGRLQLDADREASRQYFLQHVNQNTVFFHTLAEKLEYLVAENY YEQEVLDQYDFPFIKSLFERAYAVKFRFQSFLGAFKYYTSYTLKTFDGRRYLERFEDRVCMVALTLAQGDEALARQLVDE IIHGRFQPATPTFLNCGKKQRGELVSCFLLRIEDNMESIGRSINSALQLSKRGGGVAFLLSNIREAGAPIKHIENQSSGI IPIMKMLEDAFSYANQLGARQGAGAVYLNAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNEPMYLFSP YDVENVYGKPFGDISVTEKYYEMVDDARIRKTKINARELFQTLAEVQFESGYPYVMFEDTVNRANPIAGRINMSNLCSEI LQVNTPSDYEADLGYERIGEDISCNLGSLNIAKTMDSSDFGATVETAIRGLTAVSEMSDIRSVPSIAEANKQSHAIGLGQ MNLHGYLAREHIHYGSEEGLDFTNLYFYTVTYHALRASNRLAIERGRAFAGFEASDYASGVYFDKYTEQAWGPRTARVRE LFDKAGIHVPTQEDWRELKASVMAHGLFNRNLQAVPPTGSISYINHSTSSIHPVVSKIEIRKEGKLGRVYYPAPYLNDDN QDYYQDAYEIGPEKIIDTYAEATQHVDQGLSLTLFFRDTATTRDINRAQIYAWRKGIKTLYYVRLRQAALEGTEVEGCVS CTL
Sequences:
>Translated_723_residues MDDTVELTEKTPAVEASRATQTLDYHALNAMLNLYDDQGRLQLDADREASRQYFLQHVNQNTVFFHTLAEKLEYLVAENY YEQEVLDQYDFPFIKSLFERAYAVKFRFQSFLGAFKYYTSYTLKTFDGRRYLERFEDRVCMVALTLAQGDEALARQLVDE IIHGRFQPATPTFLNCGKKQRGELVSCFLLRIEDNMESIGRSINSALQLSKRGGGVAFLLSNIREAGAPIKHIENQSSGI IPIMKMLEDAFSYANQLGARQGAGAVYLNAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNEPMYLFSP YDVENVYGKPFGDISVTEKYYEMVDDARIRKTKINARELFQTLAEVQFESGYPYVMFEDTVNRANPIAGRINMSNLCSEI LQVNTPSDYEADLGYERIGEDISCNLGSLNIAKTMDSSDFGATVETAIRGLTAVSEMSDIRSVPSIAEANKQSHAIGLGQ MNLHGYLAREHIHYGSEEGLDFTNLYFYTVTYHALRASNRLAIERGRAFAGFEASDYASGVYFDKYTEQAWGPRTARVRE LFDKAGIHVPTQEDWRELKASVMAHGLFNRNLQAVPPTGSISYINHSTSSIHPVVSKIEIRKEGKLGRVYYPAPYLNDDN QDYYQDAYEIGPEKIIDTYAEATQHVDQGLSLTLFFRDTATTRDINRAQIYAWRKGIKTLYYVRLRQAALEGTEVEGCVS CTL >Mature_723_residues MDDTVELTEKTPAVEASRATQTLDYHALNAMLNLYDDQGRLQLDADREASRQYFLQHVNQNTVFFHTLAEKLEYLVAENY YEQEVLDQYDFPFIKSLFERAYAVKFRFQSFLGAFKYYTSYTLKTFDGRRYLERFEDRVCMVALTLAQGDEALARQLVDE IIHGRFQPATPTFLNCGKKQRGELVSCFLLRIEDNMESIGRSINSALQLSKRGGGVAFLLSNIREAGAPIKHIENQSSGI IPIMKMLEDAFSYANQLGARQGAGAVYLNAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNEPMYLFSP YDVENVYGKPFGDISVTEKYYEMVDDARIRKTKINARELFQTLAEVQFESGYPYVMFEDTVNRANPIAGRINMSNLCSEI LQVNTPSDYEADLGYERIGEDISCNLGSLNIAKTMDSSDFGATVETAIRGLTAVSEMSDIRSVPSIAEANKQSHAIGLGQ MNLHGYLAREHIHYGSEEGLDFTNLYFYTVTYHALRASNRLAIERGRAFAGFEASDYASGVYFDKYTEQAWGPRTARVRE LFDKAGIHVPTQEDWRELKASVMAHGLFNRNLQAVPPTGSISYINHSTSSIHPVVSKIEIRKEGKLGRVYYPAPYLNDDN QDYYQDAYEIGPEKIIDTYAEATQHVDQGLSLTLFFRDTATTRDINRAQIYAWRKGIKTLYYVRLRQAALEGTEVEGCVS CTL
Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]
COG id: COG0209
COG function: function code F; Ribonucleotide reductase, alpha subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the ribonucleoside diphosphate reductase large chain family [H]
Homologues:
Organism=Homo sapiens, GI4506749, Length=636, Percent_Identity=26.7295597484277, Blast_Score=194, Evalue=2e-49, Organism=Escherichia coli, GI1789030, Length=703, Percent_Identity=74.3954480796586, Blast_Score=1110, Evalue=0.0, Organism=Escherichia coli, GI2367133, Length=562, Percent_Identity=25.8007117437722, Blast_Score=171, Evalue=2e-43, Organism=Caenorhabditis elegans, GI17555242, Length=644, Percent_Identity=25.4658385093168, Blast_Score=185, Evalue=8e-47, Organism=Saccharomyces cerevisiae, GI6322123, Length=650, Percent_Identity=26.4615384615385, Blast_Score=195, Evalue=3e-50, Organism=Saccharomyces cerevisiae, GI6320914, Length=651, Percent_Identity=26.7281105990783, Blast_Score=194, Evalue=4e-50, Organism=Drosophila melanogaster, GI17352481, Length=646, Percent_Identity=26.3157894736842, Blast_Score=182, Evalue=7e-46,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013346 - InterPro: IPR013509 - InterPro: IPR000788 - InterPro: IPR008926 - InterPro: IPR013554 [H]
Pfam domain/function: PF02867 Ribonuc_red_lgC; PF00317 Ribonuc_red_lgN; PF08343 RNR_N [H]
EC number: =1.17.4.1 [H]
Molecular weight: Translated: 82067; Mature: 82067
Theoretical pI: Translated: 5.37; Mature: 5.37
Prosite motif: PS00089 RIBORED_LARGE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDDTVELTEKTPAVEASRATQTLDYHALNAMLNLYDDQGRLQLDADREASRQYFLQHVNQ CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCC NTVFFHTLAEKLEYLVAENYYEQEVLDQYDFPFIKSLFERAYAVKFRFQSFLGAFKYYTS CEEEHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YTLKTFDGRRYLERFEDRVCMVALTLAQGDEALARQLVDEIIHGRFQPATPTFLNCGKKQ HEEEECCCHHHHHHHHCCEEEEEEEHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCHH RGELVSCFLLRIEDNMESIGRSINSALQLSKRGGGVAFLLSNIREAGAPIKHIENQSSGI HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCCC IPIMKMLEDAFSYANQLGARQGAGAVYLNAHHPDILRFLDTKRENADEKIRIKTLSLGVV HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEEEEEEEE IPDITFELAKRNEPMYLFSPYDVENVYGKPFGDISVTEKYYEMVDDARIRKTKINARELF ECCHHHHHHHCCCCEEEECCCCCHHCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCHHHHH QTLAEVQFESGYPYVMFEDTVNRANPIAGRINMSNLCSEILQVNTPSDYEADLGYERIGE HHHHHHEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCC DISCNLGSLNIAKTMDSSDFGATVETAIRGLTAVSEMSDIRSVPSIAEANKQSHAIGLGQ CCCCCCCCEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEECC MNLHGYLAREHIHYGSEEGLDFTNLYFYTVTYHALRASNRLAIERGRAFAGFEASDYASG CCHHHHHHHHHHCCCCCCCCCHHHEEEEEHHHHHHHCCCCEEHCCCCEEECCCCCCCCCC VYFDKYTEQAWGPRTARVRELFDKAGIHVPTQEDWRELKASVMAHGLFNRNLQAVPPTGS CEEEHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCC ISYINHSTSSIHPVVSKIEIRKEGKLGRVYYPAPYLNDDNQDYYQDAYEIGPEKIIDTYA EEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHH EATQHVDQGLSLTLFFRDTATTRDINRAQIYAWRKGIKTLYYVRLRQAALEGTEVEGCVS HHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE CTL ECC >Mature Secondary Structure MDDTVELTEKTPAVEASRATQTLDYHALNAMLNLYDDQGRLQLDADREASRQYFLQHVNQ CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCC NTVFFHTLAEKLEYLVAENYYEQEVLDQYDFPFIKSLFERAYAVKFRFQSFLGAFKYYTS CEEEHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YTLKTFDGRRYLERFEDRVCMVALTLAQGDEALARQLVDEIIHGRFQPATPTFLNCGKKQ HEEEECCCHHHHHHHHCCEEEEEEEHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCHH RGELVSCFLLRIEDNMESIGRSINSALQLSKRGGGVAFLLSNIREAGAPIKHIENQSSGI HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCCC IPIMKMLEDAFSYANQLGARQGAGAVYLNAHHPDILRFLDTKRENADEKIRIKTLSLGVV HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEEEEEEEE IPDITFELAKRNEPMYLFSPYDVENVYGKPFGDISVTEKYYEMVDDARIRKTKINARELF ECCHHHHHHHCCCCEEEECCCCCHHCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCHHHHH QTLAEVQFESGYPYVMFEDTVNRANPIAGRINMSNLCSEILQVNTPSDYEADLGYERIGE HHHHHHEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCC DISCNLGSLNIAKTMDSSDFGATVETAIRGLTAVSEMSDIRSVPSIAEANKQSHAIGLGQ CCCCCCCCEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEECC MNLHGYLAREHIHYGSEEGLDFTNLYFYTVTYHALRASNRLAIERGRAFAGFEASDYASG CCHHHHHHHHHHCCCCCCCCCHHHEEEEEHHHHHHHCCCCEEHCCCCEEECCCCCCCCCC VYFDKYTEQAWGPRTARVRELFDKAGIHVPTQEDWRELKASVMAHGLFNRNLQAVPPTGS CEEEHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCC ISYINHSTSSIHPVVSKIEIRKEGKLGRVYYPAPYLNDDNQDYYQDAYEIGPEKIIDTYA EEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHH EATQHVDQGLSLTLFFRDTATTRDINRAQIYAWRKGIKTLYYVRLRQAALEGTEVEGCVS HHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE CTL ECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]