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The map label for this gene is xylB [H]

Identifier: 92112482

GI number: 92112482

Start: 390264

End: 391355

Strand: Direct

Name: xylB [H]

Synonym: Csal_0349

Alternate gene names: 92112482

Gene position: 390264-391355 (Clockwise)

Preceding gene: 92112481

Following gene: 92112484

Centisome position: 10.56

GC content: 66.21

Gene sequence:

>1092_bases
ATGCAAATCAAAGCGGCCGTGACGCGAGACAAGGGCGGGCCCTTCTCGGTGGAGACCCTGACCTTGACCGAGCCGGGGGC
CAGCGAGTTGCGCCTGCGCATCGTGGCCACCGGGGTGTGCCACACGGATGCCGTCGCCCGGGACCTGGAACTGACGCCGT
TCCCCGTCGTTCTGGGGCACGAGGGCGCCGGGGTGGTGGAAGCCGTGGGGAGCGAGGTCACGGCGTTCGCGCCGGGGGAC
CATGTCGTGCTGTCGTTTGCCCATTGCGGCGCATGCGAGCATTGCCTGACCGGTCACCCTACCGTGTGCATGCGCATGAA
CGAGTTGAATTTCGGCGGGCGTGCCGAGAACGGGACCTGCTACCTGCATCGAGGCGACGAAGCGGTGTCCACCTTCTTCG
GGCAGTCCTCGTTCGGGTCCCATGCGGTGGTGCATGAGCGCAACGCGGTCAAGGTGGATCCGGATCTCGATCTGGGCTTG
CTGGCCCCCTTGGGCTGTGGCGTTCAGACCGGGAGCGGCACGGTTCTCAATCGCCTCAAGCCTGCGTCCGGCAGCAGCCT
GGTGGTCTACGGCTGCGGCGCGGTGGGGTTGAGCGCCGTCATGGCGGCCCGTATCGCCGGCTGCGCGCGGATCATCGCCG
TCGACGTGCACGACAATCGCTTGTCGCTCGCCAAGGAGCTGGGGGCCACGCACGTCTTCAACGGCCGCCAGGTGGACGTG
GTGGAGGAGATTCGTGCCGTGACCGGCGCGGGGGCGCACTACGCCGTCGAAACGACCGGCGTGCCGCAGGTGGTGCGCCA
GGGGTTGCATGCGTTGCGCCCGCTGGGCCAGCTGGCCATCGTGGGGGTGACGCCGGAGGTCACGCTGGATGTGCACAATG
ACCTGATGGCGGAAGGCAAGACCATGCTGGGCGTGATCGAGGGCGACTCGGTGCCCAAGGTGTTCATTCCCCAGCTCATC
GACTACTACCGCCAGGGGCAATTCCCGTTCGACAAGCTGGTGACGTTTTACGAGTTCGATGCCCTGGAAGAGGCATTCGC
GGATTCCAAGTCCGGCAAGACCATCAAGCCGGTGGTGCGGATGAATTCATAG

Upstream 100 bases:

>100_bases
ATGAGCCGCGCCAGTATCCGTTCTAACCCGCAGCCGGGAACGATACCCGGGCCGAGGCATGGCCCGGGGACGTTCACCGC
AACGTCGTGAGGAGCTTTCC

Downstream 100 bases:

>100_bases
TGGGCAAGTGCCAGGACAACGGATGAGTGGCGACAGGCCCGGCAGAATCACTATCTGCGCCGTCGTTTGGGCGAAAGCAT
TCGCACGCGGGCTCTAGAAC

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: Benzyl alcohol dehydrogenase; BADH [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MQIKAAVTRDKGGPFSVETLTLTEPGASELRLRIVATGVCHTDAVARDLELTPFPVVLGHEGAGVVEAVGSEVTAFAPGD
HVVLSFAHCGACEHCLTGHPTVCMRMNELNFGGRAENGTCYLHRGDEAVSTFFGQSSFGSHAVVHERNAVKVDPDLDLGL
LAPLGCGVQTGSGTVLNRLKPASGSSLVVYGCGAVGLSAVMAARIAGCARIIAVDVHDNRLSLAKELGATHVFNGRQVDV
VEEIRAVTGAGAHYAVETTGVPQVVRQGLHALRPLGQLAIVGVTPEVTLDVHNDLMAEGKTMLGVIEGDSVPKVFIPQLI
DYYRQGQFPFDKLVTFYEFDALEEAFADSKSGKTIKPVVRMNS

Sequences:

>Translated_363_residues
MQIKAAVTRDKGGPFSVETLTLTEPGASELRLRIVATGVCHTDAVARDLELTPFPVVLGHEGAGVVEAVGSEVTAFAPGD
HVVLSFAHCGACEHCLTGHPTVCMRMNELNFGGRAENGTCYLHRGDEAVSTFFGQSSFGSHAVVHERNAVKVDPDLDLGL
LAPLGCGVQTGSGTVLNRLKPASGSSLVVYGCGAVGLSAVMAARIAGCARIIAVDVHDNRLSLAKELGATHVFNGRQVDV
VEEIRAVTGAGAHYAVETTGVPQVVRQGLHALRPLGQLAIVGVTPEVTLDVHNDLMAEGKTMLGVIEGDSVPKVFIPQLI
DYYRQGQFPFDKLVTFYEFDALEEAFADSKSGKTIKPVVRMNS
>Mature_363_residues
MQIKAAVTRDKGGPFSVETLTLTEPGASELRLRIVATGVCHTDAVARDLELTPFPVVLGHEGAGVVEAVGSEVTAFAPGD
HVVLSFAHCGACEHCLTGHPTVCMRMNELNFGGRAENGTCYLHRGDEAVSTFFGQSSFGSHAVVHERNAVKVDPDLDLGL
LAPLGCGVQTGSGTVLNRLKPASGSSLVVYGCGAVGLSAVMAARIAGCARIIAVDVHDNRLSLAKELGATHVFNGRQVDV
VEEIRAVTGAGAHYAVETTGVPQVVRQGLHALRPLGQLAIVGVTPEVTLDVHNDLMAEGKTMLGVIEGDSVPKVFIPQLI
DYYRQGQFPFDKLVTFYEFDALEEAFADSKSGKTIKPVVRMNS

Specific function: Oxidizes primary alcohols with an aromatic or cyclohex- 1-ene ring. It is highly specific for benzyl alcohol [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI34577061, Length=367, Percent_Identity=35.9673024523161, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI4501929, Length=366, Percent_Identity=34.9726775956284, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI4501933, Length=367, Percent_Identity=34.8773841961853, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI71565152, Length=371, Percent_Identity=33.6927223719677, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI71565154, Length=370, Percent_Identity=33.5135135135135, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI156523966, Length=370, Percent_Identity=32.1621621621622, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI4501939, Length=362, Percent_Identity=32.5966850828729, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI262073058, Length=366, Percent_Identity=30.6010928961749, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI71743840, Length=366, Percent_Identity=30.6010928961749, Blast_Score=176, Evalue=3e-44,
Organism=Escherichia coli, GI1786552, Length=368, Percent_Identity=33.4239130434783, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1788073, Length=373, Percent_Identity=26.5415549597855, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI87081918, Length=340, Percent_Identity=30.8823529411765, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788407, Length=279, Percent_Identity=26.8817204301075, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1787863, Length=348, Percent_Identity=24.4252873563218, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082125, Length=352, Percent_Identity=24.4318181818182, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788075, Length=301, Percent_Identity=27.5747508305648, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786518, Length=304, Percent_Identity=29.9342105263158, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790045, Length=357, Percent_Identity=23.249299719888, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25146526, Length=371, Percent_Identity=33.4231805929919, Blast_Score=194, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71997431, Length=373, Percent_Identity=33.2439678284182, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17565904, Length=337, Percent_Identity=33.5311572700297, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI17562584, Length=356, Percent_Identity=26.9662921348315, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17562878, Length=274, Percent_Identity=29.9270072992701, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71988145, Length=289, Percent_Identity=25.9515570934256, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562876, Length=358, Percent_Identity=24.3016759776536, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562582, Length=299, Percent_Identity=27.7591973244147, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320033, Length=371, Percent_Identity=32.8840970350404, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6319621, Length=291, Percent_Identity=26.8041237113402, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323729, Length=291, Percent_Identity=27.1477663230241, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=291, Percent_Identity=26.1168384879725, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=306, Percent_Identity=26.4705882352941, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319258, Length=260, Percent_Identity=26.5384615384615, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17737895, Length=370, Percent_Identity=31.6216216216216, Blast_Score=176, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.90 [H]

Molecular weight: Translated: 38311; Mature: 38311

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKAAVTRDKGGPFSVETLTLTEPGASELRLRIVATGVCHTDAVARDLELTPFPVVLGH
CCEEEEEECCCCCCEEEEEEEEECCCHHHEEEEEEEECCCCCHHHHHCCCCCCCEEEECC
EGAGVVEAVGSEVTAFAPGDHVVLSFAHCGACEHCLTGHPTVCMRMNELNFGGRAENGTC
CCCCHHHHCCCCEEEECCCCEEEEEEECCCCHHHHHCCCCEEEEEEECCCCCCCCCCCEE
YLHRGDEAVSTFFGQSSFGSHAVVHERNAVKVDPDLDLGLLAPLGCGVQTGSGTVLNRLK
EEECCCHHHHHHHCCCCCCCEEEEECCCCEEECCCCCCHHHCCCCCCEECCCCHHHHCCC
PASGSSLVVYGCGAVGLSAVMAARIAGCARIIAVDVHDNRLSLAKELGATHVFNGRQVDV
CCCCCEEEEEECCHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHCCCEEEECCCEEHH
VEEIRAVTGAGAHYAVETTGVPQVVRQGLHALRPLGQLAIVGVTPEVTLDVHNDLMAEGK
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECHHHHHCCC
TMLGVIEGDSVPKVFIPQLIDYYRQGQFPFDKLVTFYEFDALEEAFADSKSGKTIKPVVR
EEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECEEE
MNS
ECC
>Mature Secondary Structure
MQIKAAVTRDKGGPFSVETLTLTEPGASELRLRIVATGVCHTDAVARDLELTPFPVVLGH
CCEEEEEECCCCCCEEEEEEEEECCCHHHEEEEEEEECCCCCHHHHHCCCCCCCEEEECC
EGAGVVEAVGSEVTAFAPGDHVVLSFAHCGACEHCLTGHPTVCMRMNELNFGGRAENGTC
CCCCHHHHCCCCEEEECCCCEEEEEEECCCCHHHHHCCCCEEEEEEECCCCCCCCCCCEE
YLHRGDEAVSTFFGQSSFGSHAVVHERNAVKVDPDLDLGLLAPLGCGVQTGSGTVLNRLK
EEECCCHHHHHHHCCCCCCCEEEEECCCCEEECCCCCCHHHCCCCCCEECCCCHHHHCCC
PASGSSLVVYGCGAVGLSAVMAARIAGCARIIAVDVHDNRLSLAKELGATHVFNGRQVDV
CCCCCEEEEEECCHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHCCCEEEECCCEEHH
VEEIRAVTGAGAHYAVETTGVPQVVRQGLHALRPLGQLAIVGVTPEVTLDVHNDLMAEGK
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECHHHHHCCC
TMLGVIEGDSVPKVFIPQLIDYYRQGQFPFDKLVTFYEFDALEEAFADSKSGKTIKPVVR
EEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECEEE
MNS
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8496150; 1989592 [H]