The gene/protein map for NC_007951 is currently unavailable.
Definition Burkholderia xenovorans LB400 chromosome 1, complete sequence.
Accession NC_007951
Length 4,895,836

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The map label for this gene is livF [H]

Identifier: 91785755

GI number: 91785755

Start: 4828358

End: 4829116

Strand: Reverse

Name: livF [H]

Synonym: Bxe_A0018

Alternate gene names: 91785755

Gene position: 4829116-4828358 (Counterclockwise)

Preceding gene: 91785756

Following gene: 91785754

Centisome position: 98.64

GC content: 62.06

Gene sequence:

>759_bases
ATGAATACGATTGCCGAGCGTGAAAGCCTCGAAGTGAGCGGTACGGACGGCGCCGCTGCCGCGCTGGACATCAAGGGATT
GCAGGCGTGGTACGGCGAATCCCACATTCTGCATGGCGTCGATCTGACGGTGAACCGCGGCGAAGTCGTCACGCTGCTGG
GCCGCAACGGCGCGGGGCGGACCACCACGCTGCGCGCCATCATGGGCCTGACCGGACGGCGCACCGGCTCGATCCGCATT
GGCGGGCGCGAAACCGTCAATCTGCCCACGCATCGCATCGCGCATTGCGGCATTGGTTACTGTCCGGAAGAGCGCGGTAT
TTTTTCGAGCCTCTCATGCGAGGAAAATCTGCTGTTGCCGCCGCCCGTCGGGGACAAGGCGCACATGATGTCGCTCGAAG
AAATCTATTCGATGTTTCCGAATCTGCATGAACGCCGCATGAGCCAGGGTACGCGGCTCTCGGGCGGCGAACAGCAGATG
CTCGCGGTGGCGCGGATTCTGCGCACCGGCGCGAGCCTGCTGCTGCTCGACGAAATCTCGGAAGGGCTCGCGCCTGTCAT
CGTTCAGGCGTTGGCACGCATGATCATGACGCTCAAGGCGCGCGGCTATACCGTGGTGATGGTCGAGCAGAATTTTCGCT
TTGCCGCGCCGCTTGCCGATCGCTTCTACGTGATGGAGCACGGCGCAATTGTCGAGCACTTCGGGGCGAGTGAGCTCGAA
ACCAAGATGCCGATCCTGCACGATCTTTTGGGCGTATAA

Upstream 100 bases:

>100_bases
AAGTGCTCGCCGAAGGCAGTTACGCCGAAGTGTCGAAGAATCCGCTCGTGATGCAAGCCTATATGGGCAGCGCCGACGCG
GCGCTCGCCGGAGCCCACGC

Downstream 100 bases:

>100_bases
AAAACCGCCCGAATGCCTCTGATAACCACAAGCGAAGAAACCAGGAGACAGGAATGAAAAAGAACCCCCTCGCGCGGCTT
GCCACACTTTGTTTCGCGGT

Product: branched chain amino acid ABC transporter ATPase

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein F [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNTIAERESLEVSGTDGAAAALDIKGLQAWYGESHILHGVDLTVNRGEVVTLLGRNGAGRTTTLRAIMGLTGRRTGSIRI
GGRETVNLPTHRIAHCGIGYCPEERGIFSSLSCEENLLLPPPVGDKAHMMSLEEIYSMFPNLHERRMSQGTRLSGGEQQM
LAVARILRTGASLLLLDEISEGLAPVIVQALARMIMTLKARGYTVVMVEQNFRFAAPLADRFYVMEHGAIVEHFGASELE
TKMPILHDLLGV

Sequences:

>Translated_252_residues
MNTIAERESLEVSGTDGAAAALDIKGLQAWYGESHILHGVDLTVNRGEVVTLLGRNGAGRTTTLRAIMGLTGRRTGSIRI
GGRETVNLPTHRIAHCGIGYCPEERGIFSSLSCEENLLLPPPVGDKAHMMSLEEIYSMFPNLHERRMSQGTRLSGGEQQM
LAVARILRTGASLLLLDEISEGLAPVIVQALARMIMTLKARGYTVVMVEQNFRFAAPLADRFYVMEHGAIVEHFGASELE
TKMPILHDLLGV
>Mature_252_residues
MNTIAERESLEVSGTDGAAAALDIKGLQAWYGESHILHGVDLTVNRGEVVTLLGRNGAGRTTTLRAIMGLTGRRTGSIRI
GGRETVNLPTHRIAHCGIGYCPEERGIFSSLSCEENLLLPPPVGDKAHMMSLEEIYSMFPNLHERRMSQGTRLSGGEQQM
LAVARILRTGASLLLLDEISEGLAPVIVQALARMIMTLKARGYTVVMVEQNFRFAAPLADRFYVMEHGAIVEHFGASELE
TKMPILHDLLGV

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0410

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI105990541, Length=192, Percent_Identity=28.125, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI27881501, Length=215, Percent_Identity=27.4418604651163, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI30795238, Length=215, Percent_Identity=27.4418604651163, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI31657092, Length=223, Percent_Identity=25.5605381165919, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI21536376, Length=196, Percent_Identity=26.530612244898, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI45446740, Length=196, Percent_Identity=29.5918367346939, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI47078218, Length=196, Percent_Identity=29.5918367346939, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27436953, Length=195, Percent_Identity=29.2307692307692, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI116734710, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI153792144, Length=198, Percent_Identity=26.2626262626263, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4505771, Length=235, Percent_Identity=26.8085106382979, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI9961252, Length=235, Percent_Identity=26.8085106382979, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI42741659, Length=236, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI148612844, Length=222, Percent_Identity=29.7297297297297, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI255708477, Length=234, Percent_Identity=29.0598290598291, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI9961250, Length=225, Percent_Identity=28.4444444444444, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI190343023, Length=220, Percent_Identity=28.1818181818182, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI27262624, Length=217, Percent_Identity=26.7281105990783, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI27262626, Length=217, Percent_Identity=26.7281105990783, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082268, Length=211, Percent_Identity=40.7582938388626, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1789593, Length=224, Percent_Identity=34.8214285714286, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789672, Length=229, Percent_Identity=29.2576419213974, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787792, Length=219, Percent_Identity=32.4200913242009, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787029, Length=230, Percent_Identity=28.2608695652174, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788225, Length=235, Percent_Identity=29.7872340425532, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788897, Length=212, Percent_Identity=30.188679245283, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788450, Length=210, Percent_Identity=30, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1790190, Length=218, Percent_Identity=25.6880733944954, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787089, Length=228, Percent_Identity=28.5087719298246, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI48995001, Length=226, Percent_Identity=26.9911504424779, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789864, Length=248, Percent_Identity=25, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788761, Length=221, Percent_Identity=28.5067873303167, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787370, Length=222, Percent_Identity=27.027027027027, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1790162, Length=244, Percent_Identity=25, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786253, Length=224, Percent_Identity=29.9107142857143, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787712, Length=221, Percent_Identity=29.8642533936652, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787105, Length=212, Percent_Identity=25.9433962264151, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081791, Length=218, Percent_Identity=27.9816513761468, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790525, Length=229, Percent_Identity=27.0742358078603, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789991, Length=225, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786319, Length=233, Percent_Identity=26.6094420600858, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786872, Length=225, Percent_Identity=28.8888888888889, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787112, Length=231, Percent_Identity=31.1688311688312, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786398, Length=209, Percent_Identity=25.3588516746411, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87081709, Length=225, Percent_Identity=27.1111111111111, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790467, Length=226, Percent_Identity=25.6637168141593, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788644, Length=234, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786703, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790544, Length=236, Percent_Identity=27.9661016949153, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87081782, Length=173, Percent_Identity=30.0578034682081, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI48994943, Length=248, Percent_Identity=24.5967741935484, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786563, Length=212, Percent_Identity=25.9433962264151, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788165, Length=212, Percent_Identity=25.4716981132075, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=226, Percent_Identity=30.5309734513274, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115533608, Length=249, Percent_Identity=28.5140562248996, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71996809, Length=231, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71983523, Length=230, Percent_Identity=29.1304347826087, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71983510, Length=230, Percent_Identity=29.1304347826087, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71983516, Length=230, Percent_Identity=29.1304347826087, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193211017, Length=231, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193211015, Length=231, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=213, Percent_Identity=26.2910798122066, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565938, Length=217, Percent_Identity=27.1889400921659, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567265, Length=211, Percent_Identity=27.0142180094787, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71996550, Length=256, Percent_Identity=26.953125, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565586, Length=239, Percent_Identity=24.2677824267782, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115535101, Length=214, Percent_Identity=26.1682242990654, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71984940, Length=229, Percent_Identity=25.3275109170306, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25146765, Length=184, Percent_Identity=27.1739130434783, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71992066, Length=184, Percent_Identity=27.1739130434783, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86564969, Length=184, Percent_Identity=27.1739130434783, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71992070, Length=184, Percent_Identity=27.1739130434783, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=251, Percent_Identity=24.7011952191235, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=216, Percent_Identity=25.462962962963, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24648314, Length=213, Percent_Identity=27.6995305164319, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24666092, Length=229, Percent_Identity=28.82096069869, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI221512771, Length=214, Percent_Identity=26.1682242990654, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574150, Length=224, Percent_Identity=26.3392857142857, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI116007328, Length=224, Percent_Identity=26.3392857142857, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17136662, Length=225, Percent_Identity=27.1111111111111, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643674, Length=218, Percent_Identity=24.3119266055046, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653245, Length=222, Percent_Identity=26.5765765765766, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363262, Length=222, Percent_Identity=26.5765765765766, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45550390, Length=225, Percent_Identity=24.8888888888889, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28573571, Length=234, Percent_Identity=24.7863247863248, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573573, Length=234, Percent_Identity=24.7863247863248, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21357907, Length=207, Percent_Identity=27.0531400966184, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27462; Mature: 27462

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNTIAERESLEVSGTDGAAAALDIKGLQAWYGESHILHGVDLTVNRGEVVTLLGRNGAGR
CCCCCCCCCEEECCCCCCEEEEEHHHHHHHHCCCEEEECEEEEECCCCEEEEEECCCCCC
TTTLRAIMGLTGRRTGSIRIGGRETVNLPTHRIAHCGIGYCPEERGIFSSLSCEENLLLP
HHHHHHHHCCCCCCCCEEEECCCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEECC
PPVGDKAHMMSLEEIYSMFPNLHERRMSQGTRLSGGEQQMLAVARILRTGASLLLLDEIS
CCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHH
EGLAPVIVQALARMIMTLKARGYTVVMVEQNFRFAAPLADRFYVMEHGAIVEHFGASELE
CCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCHHHHEEEEECCCHHHHCCCHHHH
TKMPILHDLLGV
HHHHHHHHHHCC
>Mature Secondary Structure
MNTIAERESLEVSGTDGAAAALDIKGLQAWYGESHILHGVDLTVNRGEVVTLLGRNGAGR
CCCCCCCCCEEECCCCCCEEEEEHHHHHHHHCCCEEEECEEEEECCCCEEEEEECCCCCC
TTTLRAIMGLTGRRTGSIRIGGRETVNLPTHRIAHCGIGYCPEERGIFSSLSCEENLLLP
HHHHHHHHCCCCCCCCEEEECCCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEECC
PPVGDKAHMMSLEEIYSMFPNLHERRMSQGTRLSGGEQQMLAVARILRTGASLLLLDEIS
CCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHH
EGLAPVIVQALARMIMTLKARGYTVVMVEQNFRFAAPLADRFYVMEHGAIVEHFGASELE
CCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCHHHHEEEEECCCHHHHCCCHHHH
TKMPILHDLLGV
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]