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The map label for this gene is cof [C]

Identifier: 91785669

GI number: 91785669

Start: 4727000

End: 4727821

Strand: Reverse

Name: cof [C]

Synonym: Bxe_A0108

Alternate gene names: 91785669

Gene position: 4727821-4727000 (Counterclockwise)

Preceding gene: 91785670

Following gene: 91785665

Centisome position: 96.57

GC content: 61.07

Gene sequence:

>822_bases
ATGTACAAAGTTATCGCCACGGACCTCGACGGTACGCTGCTCAATGCCGATCACCAGGTGGACCCATTCACGGTCGCCAC
CGTGCGCAAACTCGAGAGCGACGGCCTGCACTTCGTGATTGCTACGGGCCGCCATTATTGCGACGTCGCCGGCATCCGCG
ACGTGCTGGGCATCAGCCCGTATCTGATCACGTCGAATGGCGCGCGCATCCACGCGCCGGACAACACGGTGATCCACGCC
GACGATCTGCCTCCTGCCATCGTGCAACGGCTGGTGCAGCCGGAAATTGCCGGCGCGCATGGCCGTGTGATCGTCAACCT
GTTCGCCGATCAGGCCTGGCTGATCGACCGCGACGCGCCGGATCTGCTGAAGTTTCACCAGGACTCCGGGTTCACCTATG
AGGTGACCGATCTGCCGAAACATGACGGTGCCGACATCGCGAAGGCGCTCTATATTGGCGAGCCGGCCGATCTCGCGCAG
GTCGCGGCGAATCTCGCACGCCAATTCGGCGACGCGCTTTACGTGACCTATTCGCTGCCGGACTGCCTGGAAGTGATGAC
GGCGAATGTATCGAAGGGACGGGCGTTGCAGATCGTGCTTGAGCGCGTCGGCGTCGATGCCTCGCACTGCGTGGCGTTCG
GCGACAACATGAACGATATCGATCTGCTGGAGACGGCTGGACATCCGTTCATGATGAACAACGCCAATCCCGATCTCATG
ACACGTCTGCCGAACGTGCCGCGCATTGGCAACAACTTCGAAGCGGGCGTTGCGCACCATCTGCGCAAGCTTTTCTCGCT
CGACGACGAATTGATGTCCTGA

Upstream 100 bases:

>100_bases
GCTCCCGGCTGAGAATTGCAGGAAATGGCTGGTGCGTTTCCAGTGAACCCGGCCGACGCCGGTAAAATGCTCGCTTCGAT
GTTGCCCGACTGCTCACACT

Downstream 100 bases:

>100_bases
CGGAAAATGGAAACGGCCCGCGTCCGTTTTCATGAACGCGGGCCATTTTTCGTGCGAGCCTTTCCGGGTTTCCGGTTGCT
ATCGACCGTGTGGCAGATCG

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MYKVIATDLDGTLLNADHQVDPFTVATVRKLESDGLHFVIATGRHYCDVAGIRDVLGISPYLITSNGARIHAPDNTVIHA
DDLPPAIVQRLVQPEIAGAHGRVIVNLFADQAWLIDRDAPDLLKFHQDSGFTYEVTDLPKHDGADIAKALYIGEPADLAQ
VAANLARQFGDALYVTYSLPDCLEVMTANVSKGRALQIVLERVGVDASHCVAFGDNMNDIDLLETAGHPFMMNNANPDLM
TRLPNVPRIGNNFEAGVAHHLRKLFSLDDELMS

Sequences:

>Translated_273_residues
MYKVIATDLDGTLLNADHQVDPFTVATVRKLESDGLHFVIATGRHYCDVAGIRDVLGISPYLITSNGARIHAPDNTVIHA
DDLPPAIVQRLVQPEIAGAHGRVIVNLFADQAWLIDRDAPDLLKFHQDSGFTYEVTDLPKHDGADIAKALYIGEPADLAQ
VAANLARQFGDALYVTYSLPDCLEVMTANVSKGRALQIVLERVGVDASHCVAFGDNMNDIDLLETAGHPFMMNNANPDLM
TRLPNVPRIGNNFEAGVAHHLRKLFSLDDELMS
>Mature_273_residues
MYKVIATDLDGTLLNADHQVDPFTVATVRKLESDGLHFVIATGRHYCDVAGIRDVLGISPYLITSNGARIHAPDNTVIHA
DDLPPAIVQRLVQPEIAGAHGRVIVNLFADQAWLIDRDAPDLLKFHQDSGFTYEVTDLPKHDGADIAKALYIGEPADLAQ
VAANLARQFGDALYVTYSLPDCLEVMTANVSKGRALQIVLERVGVDASHCVAFGDNMNDIDLLETAGHPFMMNNANPDLM
TRLPNVPRIGNNFEAGVAHHLRKLFSLDDELMS

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI48994981, Length=266, Percent_Identity=36.8421052631579, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI87081741, Length=261, Percent_Identity=33.3333333333333, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1786982, Length=274, Percent_Identity=25.9124087591241, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: NA

Molecular weight: Translated: 29800; Mature: 29800

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS01228 COF_1 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKVIATDLDGTLLNADHQVDPFTVATVRKLESDGLHFVIATGRHYCDVAGIRDVLGISP
CEEEEEECCCCEEECCCCCCCCCHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHHHCCCC
YLITSNGARIHAPDNTVIHADDLPPAIVQRLVQPEIAGAHGRVIVNLFADQAWLIDRDAP
EEEECCCCEEECCCCCEEECCCCCHHHHHHHHCHHCCCCCCEEEEEEECCCEEEEECCCH
DLLKFHQDSGFTYEVTDLPKHDGADIAKALYIGEPADLAQVAANLARQFGDALYVTYSLP
HHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCH
DCLEVMTANVSKGRALQIVLERVGVDASHCVAFGDNMNDIDLLETAGHPFMMNNANPDLM
HHHHHHHCCCCCCHHHHHHHHHHCCCHHHEEEECCCCCCCHHHHHCCCCEEECCCCHHHH
TRLPNVPRIGNNFEAGVAHHLRKLFSLDDELMS
HHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MYKVIATDLDGTLLNADHQVDPFTVATVRKLESDGLHFVIATGRHYCDVAGIRDVLGISP
CEEEEEECCCCEEECCCCCCCCCHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHHHCCCC
YLITSNGARIHAPDNTVIHADDLPPAIVQRLVQPEIAGAHGRVIVNLFADQAWLIDRDAP
EEEECCCCEEECCCCCEEECCCCCHHHHHHHHCHHCCCCCCEEEEEEECCCEEEEECCCH
DLLKFHQDSGFTYEVTDLPKHDGADIAKALYIGEPADLAQVAANLARQFGDALYVTYSLP
HHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCH
DCLEVMTANVSKGRALQIVLERVGVDASHCVAFGDNMNDIDLLETAGHPFMMNNANPDLM
HHHHHHHCCCCCCHHHHHHHHHHCCCHHHEEEECCCCCCCHHHHHCCCCEEECCCCHHHH
TRLPNVPRIGNNFEAGVAHHLRKLFSLDDELMS
HHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]