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The map label for this gene is dppA [H]

Identifier: 91785596

GI number: 91785596

Start: 4652691

End: 4654334

Strand: Reverse

Name: dppA [H]

Synonym: Bxe_A0181

Alternate gene names: 91785596

Gene position: 4654334-4652691 (Counterclockwise)

Preceding gene: 91785597

Following gene: 91785595

Centisome position: 95.07

GC content: 57.42

Gene sequence:

>1644_bases
ATGACGGTATCCAAGTTGCTGTTTGCAGTTCGCCAAACCTGCCTTCCAGCGCTGAGCGCCTGTGCCGTGCTGACTGCGAG
CCTTGCGCCCGCCGCAGCCGATGCGGCCACGCTGCCCGACAAGACCCTCGTGTTCTGCTCTGAAGGCAGTCCGGCGGGCT
TCGACAGCGCGCAGTACACCACCAGCGTCGAATTCAGCGCGGGCTCGTACACGGTCTACAACCGCCTGATCGAGTTCGCG
CACGGCAGCACGGATATCGAACCGAGTCTCGCCGAAAAGTGGGATGTGTCGCCCGACGGGCTGACCTATACGTTTCATTT
GCGCCACGGTGTGAAATTCCAGACCACCTCGTTTTTCAAGCCGACGCGCGAATTCAACGCGGACGACGTCGTCTTCACCT
ATCAGCGGATGCTCGATCCGGATCAGCCGTTCCGCAAGGCATACGCCGTACCGTTCCCGTATTTCACCGATCTCGGGCTC
GCCAAGAACATTGCGAAGATCGAAAAACTCGATCCGTACACGGTGCGTTTCACGCTGAAGGAAGTCGATGCGCCGTTTTT
GCAACAGATCGCGATGCCGTTCGCATCGATCCTCTCGGCGGAATATGGCGACCAGTTATTGAAAGCGGGTAAAGCGTCGG
ATATCAATCAATATCCGGTCGGCACTGGTCCGTTCATTTTTCGCAGCTATACGAAAGACGACACGATTCGCTTCGACGGC
AATCCCGATTACTGGAAGCCGGGTGTCGTCAAAGTCAGCAAGCTGATATTCGCGATTACCGTCGATCCGGCCGTGCGTCT
GCAAAAACTCAAGCGCGGCGAATGCCAGGTGATGGCGTATCCGCGTCCCGCCGATATTCCGGCGGTCAAAGCCGATGCAT
CGCTGGCCATGCCGAACCAGGTGGGTTTCAACCTCGGCTATATCGCCTACAACACCACTAAGAAGCCGCTCGACAATGTG
CTGGTGCGCCGTGCGCTCGATATGTCGATCAATAAGAAAGCGATTATCGACTCGGTGTATCAGGGGGCGGGCCAGGCTGC
CACGAACCCCATGCCGCCGACCCAGTGGGGCTATGACAAGAATCTGAAAGACGCGCCCTACGACACGGAAAAAGCCAAGG
CGCTGCTGAAACAGGCGGGTTATCCCGATGGCTTCGATCTGACGCTGTGGGCCATGCCGGTTCAACGGCCATATAACCCG
AACGCGCGTCTGATGGCGGAAATGCTGCAATCCGATTGGGCGAAGATCGGCGTCAAGGTGAAGATCGCCACTTACGAATG
GGGCGAATACATTCGCCGCGGCCATGCCGGCGAACATGAAGCGATGCTGATCGGCTGGACCGGCGATTACGGCGACCCGG
ATAACTGGCTCGGCGTATTGCTGGGTTGCGACGCGGTCAATGGCAGTAACTTTTCCAAATGGTGCTACAAACCTTACGAC
GACTTGATCAGAAAGGGCCGCGGCACCACTGACCTGGCTGAGCGCACCAAGGCTTACACGGAAGCTCAGGAAATATTCAA
AGATCAGGTTCCATTTACGCCGATCGCCCACTCCACGGTCTATCAGCCGATCAGCAAGAACGTGACGGGCTTCAAGATCG
ACCCGTTCGGCCCGACGCAATTCATGAATGTGGGGCTGAAATAA

Upstream 100 bases:

>100_bases
TCACGCGCAAACCTTGCGGCGTGTAAGCCCGCATTGAACCCGATTTTTGTGCTGTCTATGATCGAAGCGCAGCTGACGTG
GCTGCTGTGCGGAGAACGTG

Downstream 100 bases:

>100_bases
CCTCGGCGGGCCGTTTTTTTGCTGCGGCACCCCTCTGCGGCCGCACGCTCCCGGCAATGCCGGCGTGCGGCCGCGCTTAT
GCACGATGGTTTCCGATCGT

Product: ABC dipeptide transporter, periplasmic ligand binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MTVSKLLFAVRQTCLPALSACAVLTASLAPAAADAATLPDKTLVFCSEGSPAGFDSAQYTTSVEFSAGSYTVYNRLIEFA
HGSTDIEPSLAEKWDVSPDGLTYTFHLRHGVKFQTTSFFKPTREFNADDVVFTYQRMLDPDQPFRKAYAVPFPYFTDLGL
AKNIAKIEKLDPYTVRFTLKEVDAPFLQQIAMPFASILSAEYGDQLLKAGKASDINQYPVGTGPFIFRSYTKDDTIRFDG
NPDYWKPGVVKVSKLIFAITVDPAVRLQKLKRGECQVMAYPRPADIPAVKADASLAMPNQVGFNLGYIAYNTTKKPLDNV
LVRRALDMSINKKAIIDSVYQGAGQAATNPMPPTQWGYDKNLKDAPYDTEKAKALLKQAGYPDGFDLTLWAMPVQRPYNP
NARLMAEMLQSDWAKIGVKVKIATYEWGEYIRRGHAGEHEAMLIGWTGDYGDPDNWLGVLLGCDAVNGSNFSKWCYKPYD
DLIRKGRGTTDLAERTKAYTEAQEIFKDQVPFTPIAHSTVYQPISKNVTGFKIDPFGPTQFMNVGLK

Sequences:

>Translated_547_residues
MTVSKLLFAVRQTCLPALSACAVLTASLAPAAADAATLPDKTLVFCSEGSPAGFDSAQYTTSVEFSAGSYTVYNRLIEFA
HGSTDIEPSLAEKWDVSPDGLTYTFHLRHGVKFQTTSFFKPTREFNADDVVFTYQRMLDPDQPFRKAYAVPFPYFTDLGL
AKNIAKIEKLDPYTVRFTLKEVDAPFLQQIAMPFASILSAEYGDQLLKAGKASDINQYPVGTGPFIFRSYTKDDTIRFDG
NPDYWKPGVVKVSKLIFAITVDPAVRLQKLKRGECQVMAYPRPADIPAVKADASLAMPNQVGFNLGYIAYNTTKKPLDNV
LVRRALDMSINKKAIIDSVYQGAGQAATNPMPPTQWGYDKNLKDAPYDTEKAKALLKQAGYPDGFDLTLWAMPVQRPYNP
NARLMAEMLQSDWAKIGVKVKIATYEWGEYIRRGHAGEHEAMLIGWTGDYGDPDNWLGVLLGCDAVNGSNFSKWCYKPYD
DLIRKGRGTTDLAERTKAYTEAQEIFKDQVPFTPIAHSTVYQPISKNVTGFKIDPFGPTQFMNVGLK
>Mature_546_residues
TVSKLLFAVRQTCLPALSACAVLTASLAPAAADAATLPDKTLVFCSEGSPAGFDSAQYTTSVEFSAGSYTVYNRLIEFAH
GSTDIEPSLAEKWDVSPDGLTYTFHLRHGVKFQTTSFFKPTREFNADDVVFTYQRMLDPDQPFRKAYAVPFPYFTDLGLA
KNIAKIEKLDPYTVRFTLKEVDAPFLQQIAMPFASILSAEYGDQLLKAGKASDINQYPVGTGPFIFRSYTKDDTIRFDGN
PDYWKPGVVKVSKLIFAITVDPAVRLQKLKRGECQVMAYPRPADIPAVKADASLAMPNQVGFNLGYIAYNTTKKPLDNVL
VRRALDMSINKKAIIDSVYQGAGQAATNPMPPTQWGYDKNLKDAPYDTEKAKALLKQAGYPDGFDLTLWAMPVQRPYNPN
ARLMAEMLQSDWAKIGVKVKIATYEWGEYIRRGHAGEHEAMLIGWTGDYGDPDNWLGVLLGCDAVNGSNFSKWCYKPYDD
LIRKGRGTTDLAERTKAYTEAQEIFKDQVPFTPIAHSTVYQPISKNVTGFKIDPFGPTQFMNVGLK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=535, Percent_Identity=51.0280373831776, Blast_Score=571, Evalue=1e-164,
Organism=Escherichia coli, GI1787551, Length=517, Percent_Identity=34.816247582205, Blast_Score=328, Evalue=5e-91,
Organism=Escherichia coli, GI1787052, Length=535, Percent_Identity=30.0934579439252, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787762, Length=529, Percent_Identity=27.4102079395085, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1789887, Length=503, Percent_Identity=26.2425447316103, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1789397, Length=547, Percent_Identity=24.4972577696526, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1787495, Length=573, Percent_Identity=22.6876090750436, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87081878, Length=558, Percent_Identity=23.2974910394265, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60771; Mature: 60640

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSKLLFAVRQTCLPALSACAVLTASLAPAAADAATLPDKTLVFCSEGSPAGFDSAQYT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEE
TSVEFSAGSYTVYNRLIEFAHGSTDIEPSLAEKWDVSPDGLTYTFHLRHGVKFQTTSFFK
EEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEEECCCCEEEECCCCC
PTREFNADDVVFTYQRMLDPDQPFRKAYAVPFPYFTDLGLAKNIAKIEKLDPYTVRFTLK
CHHHCCCCCCEEHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHH
EVDAPFLQQIAMPFASILSAEYGDQLLKAGKASDINQYPVGTGPFIFRSYTKDDTIRFDG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEECC
NPDYWKPGVVKVSKLIFAITVDPAVRLQKLKRGECQVMAYPRPADIPAVKADASLAMPNQ
CCCCCCCHHHEEEEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCEECCCCCCCCCC
VGFNLGYIAYNTTKKPLDNVLVRRALDMSINKKAIIDSVYQGAGQAATNPMPPTQWGYDK
CCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
NLKDAPYDTEKAKALLKQAGYPDGFDLTLWAMPVQRPYNPNARLMAEMLQSDWAKIGVKV
CCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEE
KIATYEWGEYIRRGHAGEHEAMLIGWTGDYGDPDNWLGVLLGCDAVNGSNFSKWCYKPYD
EEEEEHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHEEEEEECCCCCCCCCCHHCCCCHH
DLIRKGRGTTDLAERTKAYTEAQEIFKDQVPFTPIAHSTVYQPISKNVTGFKIDPFGPTQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEECCCCCHH
FMNVGLK
HHHCCCC
>Mature Secondary Structure 
TVSKLLFAVRQTCLPALSACAVLTASLAPAAADAATLPDKTLVFCSEGSPAGFDSAQYT
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEE
TSVEFSAGSYTVYNRLIEFAHGSTDIEPSLAEKWDVSPDGLTYTFHLRHGVKFQTTSFFK
EEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEEECCCCEEEECCCCC
PTREFNADDVVFTYQRMLDPDQPFRKAYAVPFPYFTDLGLAKNIAKIEKLDPYTVRFTLK
CHHHCCCCCCEEHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHH
EVDAPFLQQIAMPFASILSAEYGDQLLKAGKASDINQYPVGTGPFIFRSYTKDDTIRFDG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEECC
NPDYWKPGVVKVSKLIFAITVDPAVRLQKLKRGECQVMAYPRPADIPAVKADASLAMPNQ
CCCCCCCHHHEEEEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCEECCCCCCCCCC
VGFNLGYIAYNTTKKPLDNVLVRRALDMSINKKAIIDSVYQGAGQAATNPMPPTQWGYDK
CCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
NLKDAPYDTEKAKALLKQAGYPDGFDLTLWAMPVQRPYNPNARLMAEMLQSDWAKIGVKV
CCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEE
KIATYEWGEYIRRGHAGEHEAMLIGWTGDYGDPDNWLGVLLGCDAVNGSNFSKWCYKPYD
EEEEEHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHEEEEEECCCCCCCCCCHHCCCCHH
DLIRKGRGTTDLAERTKAYTEAQEIFKDQVPFTPIAHSTVYQPISKNVTGFKIDPFGPTQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEECCCCCHH
FMNVGLK
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]