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The map label for this gene is dppA [H]

Identifier: 91785595

GI number: 91785595

Start: 4650628

End: 4652256

Strand: Reverse

Name: dppA [H]

Synonym: Bxe_A0182

Alternate gene names: 91785595

Gene position: 4652256-4650628 (Counterclockwise)

Preceding gene: 91785596

Following gene: 91785594

Centisome position: 95.02

GC content: 61.26

Gene sequence:

>1629_bases
ATGAAGCAAAACAATCTGTTGCGCGCCGCGCGTGTCACGACGCTCGTCGCAGCTGCAGCGGCATCGATGGTGGGCGCAAG
TGTCGCGCGCGCCGAGATTCCGAATAAAACCCTGGTTTACTGCTCAGAAGGCAGTCCTGCGGGTTTCGATCCTGCCCAAT
ACACCACGGGCACCGATTTCACGGCTAATACGTTCACCGTCTACAACCGCCTCGTCGAATTCGAACGCGGCGGCACCAAG
GTCGAACCGGGCCTCGCCGAAAAGTGGGAAGTCTCGGCGGACGGCAAAACCTACACGTTCCACCTGCGTCATGGCGTGAA
GTTCCAGACCACGTCGTTCTTCAAGCCGACGCGCGAATTCAATGCGGACGACGTCGTGTTCACGTTCCAGCGCATGCTGG
ACCCGAACTCGGCCTTCCATAAGGCTTACCCGGTCCAGTTCCCGTACTTCACGGACATGGGCCTCGACAAGCTGATCACC
AGCGTCGAAAAGGTCGATCCGTACACGGTCAAGTTCACGCTGAAGGAAGTCAACGCGCCGTTCATCCAGAATCTGGCGAT
GGAATACGCGTCGATCCTCTCGGGCGAATACGGCGACCAGTTGCTGAAGGCCGGCAAGGCGGCCGACATCAACCAGTTCC
CGGTCGGCACGGGCCCGTTCATTTTCCGCAGCTACACGAAAGACGCGACGATCCGCTTCGACGGCAATCCGGATTACTGG
AAGCCGAACACGGTGAAGATCTCCAAGCTGATCTTCTCGATCACGCCGGACGCCGGCGTGCGCGTGCAGAAGATCAAGCG
CGACGAATGCCAGGTGATGAGCTATCCGCGTCCGGCCGACATCGCGCCGCTGAAGGCCGAAGCGAACATCGCCATGCCGT
CGCAACCGGGCTTCAATCTCGGCTACCTCGCGTACAACGTGACGCACAAGCCGGTCGACAAGGTCGAAGTGCGTCAGGCG
CTCGACATGGCGATCAACAAGAAGGCGATCATCGAGTCGGTGTACCAGGGCGCGGGCCAGGCGGCCACGAACCCGATGCC
GCCGACCCAATGGTCGTACGACAAGAACCTGAAGGGCGCGTCTTACGATGCGGACAAGGCCAAGGCCTTGCTGGCGAAAG
CGGGCTATCCGAACGGCTTCGACATCACCCTCTGGGCGATGCCGGTGCAGCGCGCGTACAACCCGAACGCCCGCCTGATG
GCGGAAATGATCCAGGCCGACTGGGCCAGGATCGGCGTGAAGGCGAAGATCGTCACGTATGAATGGGGCGAGTACATCAA
GCGCGCTCACGCAGGTGAGGACGACACGATGCTGATCGGCTGGACCGGCGACAACGGCGATCCGGACAACTGGCTCGGCA
CGCTGCTCGGCTGCGAAGCGGTGAACGGCAACAACTTCTCGAAGTGGTGCTACAAGCCGTTCGACGACCTGATCCAGAAG
GGCCGCGTCACGTCCGACCAGGGCGCGCGCACCACGGCTTACATGCAGGCGCAGCAGATCTTCGCGCAGCAACTGCCGTT
CTCGCCGATCGCTCACTCCACGGTGTACCAGCCTGTCAGCAAGAAGGTGGTGGACATGCGCATCGAACCGCTAGGCTATG
CGCGCTTTGACGGCGTCAGCGTCAAGTAA

Upstream 100 bases:

>100_bases
ACTCCGATCGACATACAATTTCCTCTGCTTGTTGCTGCAAGCCAAGCTCAAGTAATATCGCGCTACGCCGGCGGGAGCCG
GCCACGAACCTGGAGGAAAC

Downstream 100 bases:

>100_bases
CCCATCAGGCAAGTCGTAAAATTCGCGCAGTACGCTTTTCGCACGGTTAGAAAACTGGTCGAAATGGTCCGGCGACCGGG
GTCACAAGCCCTCGTCGCCG

Product: ABC dipeptide transporter, periplasmic ligand binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MKQNNLLRAARVTTLVAAAAASMVGASVARAEIPNKTLVYCSEGSPAGFDPAQYTTGTDFTANTFTVYNRLVEFERGGTK
VEPGLAEKWEVSADGKTYTFHLRHGVKFQTTSFFKPTREFNADDVVFTFQRMLDPNSAFHKAYPVQFPYFTDMGLDKLIT
SVEKVDPYTVKFTLKEVNAPFIQNLAMEYASILSGEYGDQLLKAGKAADINQFPVGTGPFIFRSYTKDATIRFDGNPDYW
KPNTVKISKLIFSITPDAGVRVQKIKRDECQVMSYPRPADIAPLKAEANIAMPSQPGFNLGYLAYNVTHKPVDKVEVRQA
LDMAINKKAIIESVYQGAGQAATNPMPPTQWSYDKNLKGASYDADKAKALLAKAGYPNGFDITLWAMPVQRAYNPNARLM
AEMIQADWARIGVKAKIVTYEWGEYIKRAHAGEDDTMLIGWTGDNGDPDNWLGTLLGCEAVNGNNFSKWCYKPFDDLIQK
GRVTSDQGARTTAYMQAQQIFAQQLPFSPIAHSTVYQPVSKKVVDMRIEPLGYARFDGVSVK

Sequences:

>Translated_542_residues
MKQNNLLRAARVTTLVAAAAASMVGASVARAEIPNKTLVYCSEGSPAGFDPAQYTTGTDFTANTFTVYNRLVEFERGGTK
VEPGLAEKWEVSADGKTYTFHLRHGVKFQTTSFFKPTREFNADDVVFTFQRMLDPNSAFHKAYPVQFPYFTDMGLDKLIT
SVEKVDPYTVKFTLKEVNAPFIQNLAMEYASILSGEYGDQLLKAGKAADINQFPVGTGPFIFRSYTKDATIRFDGNPDYW
KPNTVKISKLIFSITPDAGVRVQKIKRDECQVMSYPRPADIAPLKAEANIAMPSQPGFNLGYLAYNVTHKPVDKVEVRQA
LDMAINKKAIIESVYQGAGQAATNPMPPTQWSYDKNLKGASYDADKAKALLAKAGYPNGFDITLWAMPVQRAYNPNARLM
AEMIQADWARIGVKAKIVTYEWGEYIKRAHAGEDDTMLIGWTGDNGDPDNWLGTLLGCEAVNGNNFSKWCYKPFDDLIQK
GRVTSDQGARTTAYMQAQQIFAQQLPFSPIAHSTVYQPVSKKVVDMRIEPLGYARFDGVSVK
>Mature_542_residues
MKQNNLLRAARVTTLVAAAAASMVGASVARAEIPNKTLVYCSEGSPAGFDPAQYTTGTDFTANTFTVYNRLVEFERGGTK
VEPGLAEKWEVSADGKTYTFHLRHGVKFQTTSFFKPTREFNADDVVFTFQRMLDPNSAFHKAYPVQFPYFTDMGLDKLIT
SVEKVDPYTVKFTLKEVNAPFIQNLAMEYASILSGEYGDQLLKAGKAADINQFPVGTGPFIFRSYTKDATIRFDGNPDYW
KPNTVKISKLIFSITPDAGVRVQKIKRDECQVMSYPRPADIAPLKAEANIAMPSQPGFNLGYLAYNVTHKPVDKVEVRQA
LDMAINKKAIIESVYQGAGQAATNPMPPTQWSYDKNLKGASYDADKAKALLAKAGYPNGFDITLWAMPVQRAYNPNARLM
AEMIQADWARIGVKAKIVTYEWGEYIKRAHAGEDDTMLIGWTGDNGDPDNWLGTLLGCEAVNGNNFSKWCYKPFDDLIQK
GRVTSDQGARTTAYMQAQQIFAQQLPFSPIAHSTVYQPVSKKVVDMRIEPLGYARFDGVSVK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=524, Percent_Identity=56.1068702290076, Blast_Score=604, Evalue=1e-174,
Organism=Escherichia coli, GI1787551, Length=540, Percent_Identity=34.0740740740741, Blast_Score=325, Evalue=6e-90,
Organism=Escherichia coli, GI1787052, Length=534, Percent_Identity=29.4007490636704, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1787762, Length=486, Percent_Identity=26.1316872427983, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1789887, Length=558, Percent_Identity=26.1648745519713, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1787495, Length=534, Percent_Identity=23.7827715355805, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1789397, Length=540, Percent_Identity=23.8888888888889, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI87081878, Length=546, Percent_Identity=24.5421245421245, Blast_Score=99, Evalue=7e-22,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60198; Mature: 60198

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQNNLLRAARVTTLVAAAAASMVGASVARAEIPNKTLVYCSEGSPAGFDPAQYTTGTDF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCC
TANTFTVYNRLVEFERGGTKVEPGLAEKWEVSADGKTYTFHLRHGVKFQTTSFFKPTREF
CCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEEEEEECCCEEEECCCCCCHHHC
NADDVVFTFQRMLDPNSAFHKAYPVQFPYFTDMGLDKLITSVEKVDPYTVKFTLKEVNAP
CCCHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCH
FIQNLAMEYASILSGEYGDQLLKAGKAADINQFPVGTGPFIFRSYTKDATIRFDGNPDYW
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCC
KPNTVKISKLIFSITPDAGVRVQKIKRDECQVMSYPRPADIAPLKAEANIAMPSQPGFNL
CCCCEEEEEEEEEECCCCCCEEEHHCCCCHHEECCCCCCCCCCEECCCCEECCCCCCCCE
GYLAYNVTHKPVDKVEVRQALDMAINKKAIIESVYQGAGQAATNPMPPTQWSYDKNLKGA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
SYDADKAKALLAKAGYPNGFDITLWAMPVQRAYNPNARLMAEMIQADWARIGVKAKIVTY
CCCHHHHHHHHHHCCCCCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEEE
EWGEYIKRAHAGEDDTMLIGWTGDNGDPDNWLGTLLGCEAVNGNNFSKWCYKPFDDLIQK
HHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHEEECCCCCCHHHHCCCHHHHHHC
GRVTSDQGARTTAYMQAQQIFAQQLPFSPIAHSTVYQPVSKKVVDMRIEPLGYARFDGVS
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEECCCCCEECCCCC
VK
CC
>Mature Secondary Structure
MKQNNLLRAARVTTLVAAAAASMVGASVARAEIPNKTLVYCSEGSPAGFDPAQYTTGTDF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCC
TANTFTVYNRLVEFERGGTKVEPGLAEKWEVSADGKTYTFHLRHGVKFQTTSFFKPTREF
CCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEEEEEECCCEEEECCCCCCHHHC
NADDVVFTFQRMLDPNSAFHKAYPVQFPYFTDMGLDKLITSVEKVDPYTVKFTLKEVNAP
CCCHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCH
FIQNLAMEYASILSGEYGDQLLKAGKAADINQFPVGTGPFIFRSYTKDATIRFDGNPDYW
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCC
KPNTVKISKLIFSITPDAGVRVQKIKRDECQVMSYPRPADIAPLKAEANIAMPSQPGFNL
CCCCEEEEEEEEEECCCCCCEEEHHCCCCHHEECCCCCCCCCCEECCCCEECCCCCCCCE
GYLAYNVTHKPVDKVEVRQALDMAINKKAIIESVYQGAGQAATNPMPPTQWSYDKNLKGA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
SYDADKAKALLAKAGYPNGFDITLWAMPVQRAYNPNARLMAEMIQADWARIGVKAKIVTY
CCCHHHHHHHHHHCCCCCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEEE
EWGEYIKRAHAGEDDTMLIGWTGDNGDPDNWLGTLLGCEAVNGNNFSKWCYKPFDDLIQK
HHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHEEECCCCCCHHHHCCCHHHHHHC
GRVTSDQGARTTAYMQAQQIFAQQLPFSPIAHSTVYQPVSKKVVDMRIEPLGYARFDGVS
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEECCCCCEECCCCC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]