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The map label for this gene is recQ [H]

Identifier: 91785471

GI number: 91785471

Start: 4519611

End: 4521458

Strand: Reverse

Name: recQ [H]

Synonym: Bxe_A0308

Alternate gene names: 91785471

Gene position: 4521458-4519611 (Counterclockwise)

Preceding gene: 91785472

Following gene: 91785470

Centisome position: 92.35

GC content: 62.88

Gene sequence:

>1848_bases
ATGTCCCGTCCGCTCGAAATCCTCAACGAAGTCTTCGGTTACCCCGCGTTCAGAGGACAGCAGGGCGAAATTGTCGAGCA
CGTCGCCGGCGGCGGCGATTGTCTCGTGCTGATGCCGACGGGCGGCGGCAAATCCTTGTGTTATCAGATTCCGTCGCTGG
TGCGCCGCGAGCGCGGCTTCGGCACAGGCATCGTCGTGTCTCCGCTGATCGCGCTGATGCAGGATCAGGTGGCCGCGCTT
ACAGAGGTGGGCGTGCGCGCGGCGTACCTGAATTCGACGCTGTCGAGCGCCGAGGCGATGGCGACCGAGCGTGCATTGCG
CGAAGGCGATATCGATCTCCTCTACGTGGCGCCGGAACGGTTGATGACGCCCCGTTTCCAGGAATTGCTGGAACGTACCC
GCATCGGCTTGTTCGCCATCGACGAGGCTCATTGTGTGTCGCAATGGGGACATGATTTCCGGCCGGAATACATCCAGTTG
TCGGTGCTGCACGAGCGGTTTCCGAACGTGCCTCGAATCGCGCTGACGGCCACCGCCGATGCAATCACGCGGGACGAGAT
CATCCACCGGCTCGCGCTGGACGACGCGCGCATTTTCGTGTCGAGCTTCGACCGGCCGAACATCCGCTATCGCATCGTTG
AAAAGGACAACGCGCGTACGCAGTTGCTGGACTTTATCCGCGCGGAACATTCGAAGCCGGACGGCACGACCGACGCCGGC
GTTGTCTATTGCCTGTCGCGCCGCAAGGTCGAAGAGACCGCGGAGTGGCTGAAAGAAAAAGGGATGCGTGCGCTGCCGTA
TCACGCCGGCATGGACTTCGAGATCCGTCAGAAGCATCAGGAGATGTTTCAGCGCGAGGAAGGCATCGTGATGTGCGCGA
CGATTGCATTTGGCATGGGCATCGACAAGCCGGACGTGCGTTTTGTCGCTCACCTCGACTTGCCGAAGAGCGTCGAAGGC
TATTACCAGGAAACGGGGCGCGCGGGCCGCGACGGCATGCCGGCGAATGCGTGGATGGCCTACGGCCTCGGCGACGTCGT
GCAGCAACGCAAGATGATCGACGAGTCCGACGCCGACGACGCGCACAAGCGCGTGCAGACCGGCAAGCTGGACGCGCTGC
TCGGTCTGTGCGAAGCGGCAACCTGCCGGCGGGTGCGGTTGCTGGCGTATTTCGGCGAATCGAGCAAGCCATGTGGCAAC
TGCGACAACTGTCTTGAACCGCCGGACACGTGGGATGCTACGCGTGAGGCGCAGATGGCGCTGTCGTGCGTGTTCCGCGC
GCAGCGGGCGAGCGGTTTTCATTTCGGCGCGGGACATCTGATCGACATCCTGCGCGGCAACAGCAACGAGAAAATCCTGC
AGCGTGGTCATGAGAAACTGACCACGTTCGGTATCGGTTCGGCGCTAGGCGAACCCGAGTGGCGCGCGATATTTCGCCAA
CTCGTCGCGTTCGGCTATCTGACGGTCGATCATGAGGGGTTCGGCTCGCTGGTCCTGACCGAGACGAGCAAACCCGTGCT
AAAGGGCGAGCAGAACGTCACGATGCGCCGGTACGTGAAGCCGACGCGTACACGTCAATCGTCCGGCCGCACCAGTGAAC
GCGCCGACCCGACAATCGGCATGGGACCACGTGAACGCGCCCGCTGGGAACGCCTGCGTGCGTGGCGCACCGAAACGGCG
AAGAGCGACGGCGTGCCGGCGTATGTGATCTTCCACGACGCGACGCTGGCGGAAATCGCCCGTAACGGTCCCGATTCCAT
CGAAGATTTGCGTGGCATTCCGGGCATGGGCGCACGCAAGCTCGACCGCTTCGGCGACGAATTGCTGGAAGTCGTCGCCG
CCGACTAA

Upstream 100 bases:

>100_bases
TTGTTAGGCCGAAAGGCTAACGTTGCAGGAAAGCGCGGGCGCAGCACGAATGCGTTGGTAAAATTCGTGTCACCGGCATC
ACGCTGCTTCTCTCAAATCC

Downstream 100 bases:

>100_bases
GCGCTCAGCGAGCGCCTGGCCAGGTCGGCAGGGGTACGAAACATCGCAACCTGTTGACTCCCTTAGTAATTTCGGAATAT
TATGCTAGGTTCCGGTTCTT

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MSRPLEILNEVFGYPAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPSLVRRERGFGTGIVVSPLIALMQDQVAAL
TEVGVRAAYLNSTLSSAEAMATERALREGDIDLLYVAPERLMTPRFQELLERTRIGLFAIDEAHCVSQWGHDFRPEYIQL
SVLHERFPNVPRIALTATADAITRDEIIHRLALDDARIFVSSFDRPNIRYRIVEKDNARTQLLDFIRAEHSKPDGTTDAG
VVYCLSRRKVEETAEWLKEKGMRALPYHAGMDFEIRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEG
YYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADDAHKRVQTGKLDALLGLCEAATCRRVRLLAYFGESSKPCGN
CDNCLEPPDTWDATREAQMALSCVFRAQRASGFHFGAGHLIDILRGNSNEKILQRGHEKLTTFGIGSALGEPEWRAIFRQ
LVAFGYLTVDHEGFGSLVLTETSKPVLKGEQNVTMRRYVKPTRTRQSSGRTSERADPTIGMGPRERARWERLRAWRTETA
KSDGVPAYVIFHDATLAEIARNGPDSIEDLRGIPGMGARKLDRFGDELLEVVAAD

Sequences:

>Translated_615_residues
MSRPLEILNEVFGYPAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPSLVRRERGFGTGIVVSPLIALMQDQVAAL
TEVGVRAAYLNSTLSSAEAMATERALREGDIDLLYVAPERLMTPRFQELLERTRIGLFAIDEAHCVSQWGHDFRPEYIQL
SVLHERFPNVPRIALTATADAITRDEIIHRLALDDARIFVSSFDRPNIRYRIVEKDNARTQLLDFIRAEHSKPDGTTDAG
VVYCLSRRKVEETAEWLKEKGMRALPYHAGMDFEIRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEG
YYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADDAHKRVQTGKLDALLGLCEAATCRRVRLLAYFGESSKPCGN
CDNCLEPPDTWDATREAQMALSCVFRAQRASGFHFGAGHLIDILRGNSNEKILQRGHEKLTTFGIGSALGEPEWRAIFRQ
LVAFGYLTVDHEGFGSLVLTETSKPVLKGEQNVTMRRYVKPTRTRQSSGRTSERADPTIGMGPRERARWERLRAWRTETA
KSDGVPAYVIFHDATLAEIARNGPDSIEDLRGIPGMGARKLDRFGDELLEVVAAD
>Mature_614_residues
SRPLEILNEVFGYPAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPSLVRRERGFGTGIVVSPLIALMQDQVAALT
EVGVRAAYLNSTLSSAEAMATERALREGDIDLLYVAPERLMTPRFQELLERTRIGLFAIDEAHCVSQWGHDFRPEYIQLS
VLHERFPNVPRIALTATADAITRDEIIHRLALDDARIFVSSFDRPNIRYRIVEKDNARTQLLDFIRAEHSKPDGTTDAGV
VYCLSRRKVEETAEWLKEKGMRALPYHAGMDFEIRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEGY
YQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADDAHKRVQTGKLDALLGLCEAATCRRVRLLAYFGESSKPCGNC
DNCLEPPDTWDATREAQMALSCVFRAQRASGFHFGAGHLIDILRGNSNEKILQRGHEKLTTFGIGSALGEPEWRAIFRQL
VAFGYLTVDHEGFGSLVLTETSKPVLKGEQNVTMRRYVKPTRTRQSSGRTSERADPTIGMGPRERARWERLRAWRTETAK
SDGVPAYVIFHDATLAEIARNGPDSIEDLRGIPGMGARKLDRFGDELLEVVAAD

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=650, Percent_Identity=35.2307692307692, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI14591902, Length=411, Percent_Identity=36.9829683698297, Blast_Score=280, Evalue=4e-75,
Organism=Homo sapiens, GI14591904, Length=411, Percent_Identity=36.9829683698297, Blast_Score=280, Evalue=4e-75,
Organism=Homo sapiens, GI148612816, Length=423, Percent_Identity=38.0614657210402, Blast_Score=268, Evalue=9e-72,
Organism=Homo sapiens, GI169218196, Length=593, Percent_Identity=31.0286677908938, Blast_Score=255, Evalue=7e-68,
Organism=Homo sapiens, GI110735439, Length=593, Percent_Identity=30.8600337268128, Blast_Score=254, Evalue=2e-67,
Organism=Homo sapiens, GI51242947, Length=392, Percent_Identity=38.5204081632653, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI51242943, Length=392, Percent_Identity=38.5204081632653, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI284005309, Length=358, Percent_Identity=35.195530726257, Blast_Score=188, Evalue=1e-47,
Organism=Escherichia coli, GI48994977, Length=614, Percent_Identity=44.6254071661238, Blast_Score=527, Evalue=1e-151,
Organism=Escherichia coli, GI87082221, Length=346, Percent_Identity=24.2774566473988, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=657, Percent_Identity=33.4855403348554, Blast_Score=331, Evalue=7e-91,
Organism=Caenorhabditis elegans, GI71987997, Length=410, Percent_Identity=39.7560975609756, Blast_Score=290, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI71987993, Length=410, Percent_Identity=39.7560975609756, Blast_Score=290, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI32564293, Length=674, Percent_Identity=31.8991097922849, Blast_Score=285, Evalue=6e-77,
Organism=Caenorhabditis elegans, GI17552866, Length=443, Percent_Identity=36.568848758465, Blast_Score=258, Evalue=5e-69,
Organism=Caenorhabditis elegans, GI71995718, Length=331, Percent_Identity=22.3564954682779, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71987143, Length=335, Percent_Identity=25.0746268656716, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=541, Percent_Identity=35.8595194085028, Blast_Score=351, Evalue=1e-97,
Organism=Saccharomyces cerevisiae, GI6324778, Length=336, Percent_Identity=22.6190476190476, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646066, Length=646, Percent_Identity=37.7708978328173, Blast_Score=377, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24664226, Length=476, Percent_Identity=36.1344537815126, Blast_Score=270, Evalue=3e-72,
Organism=Drosophila melanogaster, GI62472181, Length=435, Percent_Identity=37.7011494252874, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24664230, Length=435, Percent_Identity=37.7011494252874, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI21358123, Length=361, Percent_Identity=34.9030470914127, Blast_Score=205, Evalue=9e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 68660; Mature: 68529

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPLEILNEVFGYPAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPSLVRRERGF
CCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCC
GTGIVVSPLIALMQDQVAALTEVGVRAAYLNSTLSSAEAMATERALREGDIDLLYVAPER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHH
LMTPRFQELLERTRIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPNVPRIALTATAD
HCCHHHHHHHHHHCCCEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEECHH
AITRDEIIHRLALDDARIFVSSFDRPNIRYRIVEKDNARTQLLDFIRAEHSKPDGTTDAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCH
VVYCLSRRKVEETAEWLKEKGMRALPYHAGMDFEIRQKHQEMFQREEGIVMCATIAFGMG
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCC
IDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADD
CCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCCCHH
AHKRVQTGKLDALLGLCEAATCRRVRLLAYFGESSKPCGNCDNCLEPPDTWDATREAQMA
HHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LSCVFRAQRASGFHFGAGHLIDILRGNSNEKILQRGHEKLTTFGIGSALGEPEWRAIFRQ
HHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHH
LVAFGYLTVDHEGFGSLVLTETSKPVLKGEQNVTMRRYVKPTRTRQSSGRTSERADPTIG
HHHHHEEEEECCCCCCEEEECCCCCCCCCCCCCHHHHHCCCHHHHCCCCCCCCCCCCCCC
MGPRERARWERLRAWRTETAKSDGVPAYVIFHDATLAEIARNGPDSIEDLRGIPGMGARK
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHCCCCCHHHHHCCCCCCCHHH
LDRFGDELLEVVAAD
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRPLEILNEVFGYPAFRGQQGEIVEHVAGGGDCLVLMPTGGGKSLCYQIPSLVRRERGF
CCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCC
GTGIVVSPLIALMQDQVAALTEVGVRAAYLNSTLSSAEAMATERALREGDIDLLYVAPER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHH
LMTPRFQELLERTRIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPNVPRIALTATAD
HCCHHHHHHHHHHCCCEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEECHH
AITRDEIIHRLALDDARIFVSSFDRPNIRYRIVEKDNARTQLLDFIRAEHSKPDGTTDAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCH
VVYCLSRRKVEETAEWLKEKGMRALPYHAGMDFEIRQKHQEMFQREEGIVMCATIAFGMG
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCC
IDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGMPANAWMAYGLGDVVQQRKMIDESDADD
CCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCCCHH
AHKRVQTGKLDALLGLCEAATCRRVRLLAYFGESSKPCGNCDNCLEPPDTWDATREAQMA
HHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LSCVFRAQRASGFHFGAGHLIDILRGNSNEKILQRGHEKLTTFGIGSALGEPEWRAIFRQ
HHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHH
LVAFGYLTVDHEGFGSLVLTETSKPVLKGEQNVTMRRYVKPTRTRQSSGRTSERADPTIG
HHHHHEEEEECCCCCCEEEECCCCCCCCCCCCCHHHHHCCCHHHHCCCCCCCCCCCCCCC
MGPRERARWERLRAWRTETAKSDGVPAYVIFHDATLAEIARNGPDSIEDLRGIPGMGARK
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHCCCCCHHHHHCCCCCCCHHH
LDRFGDELLEVVAAD
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]