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The map label for this gene is obgE [H]

Identifier: 91785270

GI number: 91785270

Start: 4317306

End: 4318427

Strand: Reverse

Name: obgE [H]

Synonym: Bxe_A0509

Alternate gene names: 91785270

Gene position: 4318427-4317306 (Counterclockwise)

Preceding gene: 91785271

Following gene: 91785269

Centisome position: 88.21

GC content: 65.06

Gene sequence:

>1122_bases
ATGAAGTTCATTGACGAAGCGAGGATTGAAGTCATCGCCGGCGACGGAGGGGATGGCAGCGCGTCGATGCGCCGCGAGAA
ATTCGTTCCGTTCGGCGGCCCGGATGGCGGCGACGGCGGCCGGGGCGGCAGCGTGATCGCGGTCGCGGACCGCAACATCA
ACACGCTGATCGACTATCGCTACGCGAAGAAACACCTGGCGCGCAACGGCGAAAACGGCCGCGGTGCGGACTGCTACGGC
AAGGGCGGCGACGACATCACGCTGCGCATGCCGGTGGGCACCACCATCACCGACATGGAGACCGGCGAGCTGATCGCCGA
TCTGACCGAGCACAACCAGAGCGTGCAGATCGCTCAGGGCGGCGCGGGCGGTCTCGGTAACCTGCATTTCAAATCCAGCA
CGAACCGCGCGCCGCGTCAGAAGACGGACGGCAAGCCGGGCGAGCGCCGCATGGTGCGCCTCGAGTTGAAGGTGTTGGCG
GACGTCGGTCTGCTCGGCATGCCGAACGCGGGCAAGTCGACCTTCATCTCGTCGGTGTCGAACGCAAGGCCGAAGATCGC
CGATTACCCGTTCACCACGCTCGCGCCGAATCTCGGCGTGGTGCGTGTCGGGCCGAGCCGCAGCTTCGTGATTGCGGACA
TTCCCGGCCTGATCGAGGGCGCGGCGGAAGGCGCGGGCCTCGGTCATCAGTTCCTGCGCCATCTGCAGCGCACGGGTTTG
TTGCTGCACATCGTCGACCTCGCGCCGTTCGACGAATCGGTCGATCCGGTCGCGGAAGCCAAGGCGATCGTCAACGAACT
GCGCAAGTACGACGAACTGCTGTATGAAAAGCCGCGCTGGCTGGTGTTGAACAAGCTGGATATGGTGCCGGAAGACGAGC
GCGAAGCGCGTGTCTCGGCATTTATCGAGGGCTTTGGCTGGGACGGTCCGGTGTTCGAAATCTCGGCGCTGACTGGCCAG
GGCTGTGAAAACCTTTGCTACGCGGTGTTCGACTACATCGCCGCGCATTCGGACGCACAGCGCGCGGCCGAGGCCGAAGA
TCTCGCCGCCGACGTGCGTTTCCGCGCGAAGCCGGCAGATCCGGTCGCAGCGGACGACTCCGGCGTCGACCCGCAGCAAT
AA

Upstream 100 bases:

>100_bases
CGATTGATCAGCACGCGGCGGGCGCGGCAAAATAGCATCATCCAGTAGCAACCCAATCTGGCAGCACTATCTGGCAGCAC
ACCACGGAACGGAGTTACGC

Downstream 100 bases:

>100_bases
GAAAGCTCGAGCACCGGCACCCGAGCGGGCTGCCGGTTTGCATCACGCGTCATCTTGGGAGACTGCGCATAATGCGTTCC
GTCATCGCAGATTCACGGCG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVIAVADRNINTLIDYRYAKKHLARNGENGRGADCYG
KGGDDITLRMPVGTTITDMETGELIADLTEHNQSVQIAQGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMVRLELKVLA
DVGLLGMPNAGKSTFISSVSNARPKIADYPFTTLAPNLGVVRVGPSRSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHIVDLAPFDESVDPVAEAKAIVNELRKYDELLYEKPRWLVLNKLDMVPEDEREARVSAFIEGFGWDGPVFEISALTGQ
GCENLCYAVFDYIAAHSDAQRAAEAEDLAADVRFRAKPADPVAADDSGVDPQQ

Sequences:

>Translated_373_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVIAVADRNINTLIDYRYAKKHLARNGENGRGADCYG
KGGDDITLRMPVGTTITDMETGELIADLTEHNQSVQIAQGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMVRLELKVLA
DVGLLGMPNAGKSTFISSVSNARPKIADYPFTTLAPNLGVVRVGPSRSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHIVDLAPFDESVDPVAEAKAIVNELRKYDELLYEKPRWLVLNKLDMVPEDEREARVSAFIEGFGWDGPVFEISALTGQ
GCENLCYAVFDYIAAHSDAQRAAEAEDLAADVRFRAKPADPVAADDSGVDPQQ
>Mature_373_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVIAVADRNINTLIDYRYAKKHLARNGENGRGADCYG
KGGDDITLRMPVGTTITDMETGELIADLTEHNQSVQIAQGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMVRLELKVLA
DVGLLGMPNAGKSTFISSVSNARPKIADYPFTTLAPNLGVVRVGPSRSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHIVDLAPFDESVDPVAEAKAIVNELRKYDELLYEKPRWLVLNKLDMVPEDEREARVSAFIEGFGWDGPVFEISALTGQ
GCENLCYAVFDYIAAHSDAQRAAEAEDLAADVRFRAKPADPVAADDSGVDPQQ

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=338, Percent_Identity=39.0532544378698, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI111955139, Length=302, Percent_Identity=35.7615894039735, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI111955063, Length=180, Percent_Identity=36.6666666666667, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI58761500, Length=133, Percent_Identity=32.3308270676692, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4758796, Length=119, Percent_Identity=34.453781512605, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1789574, Length=346, Percent_Identity=56.6473988439306, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI1787454, Length=128, Percent_Identity=33.59375, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=326, Percent_Identity=38.0368098159509, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=309, Percent_Identity=32.3624595469256, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=35.15625, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321962, Length=197, Percent_Identity=36.5482233502538, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6321773, Length=158, Percent_Identity=28.4810126582279, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585318, Length=230, Percent_Identity=44.7826086956522, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI20129375, Length=336, Percent_Identity=35.7142857142857, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24640873, Length=133, Percent_Identity=33.0827067669173, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24640877, Length=133, Percent_Identity=33.0827067669173, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24640875, Length=133, Percent_Identity=33.0827067669173, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 40001; Mature: 40001

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVIAVADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHH
YAKKHLARNGENGRGADCYGKGGDDITLRMPVGTTITDMETGELIADLTEHNQSVQIAQG
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCHHHHHHHHHCCCEEEEECC
GAGGLGNLHFKSSTNRAPRQKTDGKPGERRMVRLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHEEEEEEEHHHHCCCCCCCCCCCHHHHHHHHH
NARPKIADYPFTTLAPNLGVVRVGPSRSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHHCCE
LLHIVDLAPFDESVDPVAEAKAIVNELRKYDELLYEKPRWLVLNKLDMVPEDEREARVSA
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHH
FIEGFGWDGPVFEISALTGQGCENLCYAVFDYIAAHSDAQRAAEAEDLAADVRFRAKPAD
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEECCCCC
PVAADDSGVDPQQ
CCCCCCCCCCCCC
>Mature Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVIAVADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHH
YAKKHLARNGENGRGADCYGKGGDDITLRMPVGTTITDMETGELIADLTEHNQSVQIAQG
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCHHHHHHHHHCCCEEEEECC
GAGGLGNLHFKSSTNRAPRQKTDGKPGERRMVRLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHEEEEEEEHHHHCCCCCCCCCCCHHHHHHHHH
NARPKIADYPFTTLAPNLGVVRVGPSRSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHHCCE
LLHIVDLAPFDESVDPVAEAKAIVNELRKYDELLYEKPRWLVLNKLDMVPEDEREARVSA
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHH
FIEGFGWDGPVFEISALTGQGCENLCYAVFDYIAAHSDAQRAAEAEDLAADVRFRAKPAD
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEECCCCC
PVAADDSGVDPQQ
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA