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The map label for this gene is sucC [H]

Identifier: 91785106

GI number: 91785106

Start: 4138858

End: 4140027

Strand: Reverse

Name: sucC [H]

Synonym: Bxe_A0674

Alternate gene names: 91785106

Gene position: 4140027-4138858 (Counterclockwise)

Preceding gene: 91785107

Following gene: 91785105

Centisome position: 84.56

GC content: 61.88

Gene sequence:

>1170_bases
ATGAAGATTCACGAGTACCAGGGTAAGGAAATCCTGCGGAAATTCGGCGTCGCGGTACCGCGCGGCAAGCCGGTCTTCTC
GGTGGATGATGCGGTCAAGGCCGCGGAAGAGCTCGGCGGCCCGGTATGGGTCGTGAAGGCTCAGATCCACGCGGGTGGCC
GTGGCAAGGGCGGCGGCGTGAAGGTCGCCAAGTCGCTGGAACAGGTTCGCGAATACGCGAACCAGATCCTCGGCATGCAG
CTCGTCACGCACCAGACCGGCCCGGAAGGCCAGAAGGTGAATCGTCTGCTGATCGAAGAAGGCGCTGACATCAAGAAGGA
ACTGTATGTCGGCCTCGTGATCGATCGCGTGTCGCAGAAGATCGTCGTGATGGCATCGAGCGAAGGCGGCATGGACGTCG
AAGAAGTCGCGGAAAAGACGCCTGAGCTGATCCACAAGATCGCCGTCGACCCGGCAACCGGTCTGAAAGACGCCGAAGCC
GACGAGCTCGCAACGAAGATCGGCGTGCCCGCCGCTTCGCTGCCGCAAGCTCGCGCGATCCTGCAAGGCCTGTACAAGGC
ATTCTGGGAAACGGACGCATCGCTCGCCGAAATCAACCCGCTGATCCTGACCGGCGACGGCAAGGTCATCGCGCTGGACG
CCAAGTTCAACTTCGATTCGAACGCACTGTTCCGTCACCCGGAAATCGTCGCGTATCGCGATCTGGACGAGGAAGATCCG
GCTGAAGTCGAAGCGTCGAAGTTCGACCTCGCGTACATCTCGCTCGACGGCAACATCGGCTGCCTCGTGAACGGCGCCGG
CCTCGCAATGGCAACGATGGACACCATCAAGCTGTTCGGCGGCGAACCGGCGAACTTCCTGGACGTGGGCGGTGGCGCCA
CGACCGAGAAGGTCACGGAAGCGTTCAAGATCATGCTGAAGAACCCGAACCTGACGGCGATTCTGGTCAACATTTTCGGC
GGCATCATGCGCTGCGACGTGATCGCGGAAGGCGTGATCGCGGCGTCGAAGGCCGTCTCGCTGAAGGTGCCGCTCGTGGT
CCGCATGAAGGGCACGAACGAAGACCTCGGCAAGAAGATGCTCGCTGAATCCGGCCTGCCGATCATTGCGGCGGACAGCA
TGGAAGAAGCGGCTCAGAAGGTGGTCGCGGCCGCTTCGGGCAAGGCTTGA

Upstream 100 bases:

>100_bases
GGACAGTCCGCCAGGCAGCCGAAGGCGGCGACACGTCCGGCATGAACGACGGCAGCGGAAACGAAGTTCAATCCAACTCT
CAGACTGAAGGGAATCACGC

Downstream 100 bases:

>100_bases
GCCTGGTCCGCAAGTTTTTGCGAGACGCTTTTTCCAGGTAACCAGGATTACGAATGGCGGCGCGGGAATGGCGCATGAGC
GGCGCGGGCGAAGAACATCC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKIHEYQGKEILRKFGVAVPRGKPVFSVDDAVKAAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYANQILGMQ
LVTHQTGPEGQKVNRLLIEEGADIKKELYVGLVIDRVSQKIVVMASSEGGMDVEEVAEKTPELIHKIAVDPATGLKDAEA
DELATKIGVPAASLPQARAILQGLYKAFWETDASLAEINPLILTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEVEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKIMLKNPNLTAILVNIFG
GIMRCDVIAEGVIAASKAVSLKVPLVVRMKGTNEDLGKKMLAESGLPIIAADSMEEAAQKVVAAASGKA

Sequences:

>Translated_389_residues
MKIHEYQGKEILRKFGVAVPRGKPVFSVDDAVKAAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYANQILGMQ
LVTHQTGPEGQKVNRLLIEEGADIKKELYVGLVIDRVSQKIVVMASSEGGMDVEEVAEKTPELIHKIAVDPATGLKDAEA
DELATKIGVPAASLPQARAILQGLYKAFWETDASLAEINPLILTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEVEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKIMLKNPNLTAILVNIFG
GIMRCDVIAEGVIAASKAVSLKVPLVVRMKGTNEDLGKKMLAESGLPIIAADSMEEAAQKVVAAASGKA
>Mature_389_residues
MKIHEYQGKEILRKFGVAVPRGKPVFSVDDAVKAAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYANQILGMQ
LVTHQTGPEGQKVNRLLIEEGADIKKELYVGLVIDRVSQKIVVMASSEGGMDVEEVAEKTPELIHKIAVDPATGLKDAEA
DELATKIGVPAASLPQARAILQGLYKAFWETDASLAEINPLILTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEVEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKIMLKNPNLTAILVNIFG
GIMRCDVIAEGVIAASKAVSLKVPLVVRMKGTNEDLGKKMLAESGLPIIAADSMEEAAQKVVAAASGKA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=47.3007712082262, Blast_Score=356, Evalue=2e-98,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=45.6919060052219, Blast_Score=330, Evalue=1e-90,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=45.9610027855153, Blast_Score=313, Evalue=2e-85,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=54.1237113402062, Blast_Score=416, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17539378, Length=397, Percent_Identity=46.3476070528967, Blast_Score=347, Evalue=5e-96,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=44.3589743589744, Blast_Score=331, Evalue=4e-91,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=44.6428571428571, Blast_Score=351, Evalue=1e-97,
Organism=Drosophila melanogaster, GI21356231, Length=392, Percent_Identity=44.8979591836735, Blast_Score=331, Evalue=6e-91,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=43.765903307888, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=43.765903307888, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=43.9086294416244, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=43.9086294416244, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI281363475, Length=410, Percent_Identity=26.0975609756098, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281363473, Length=410, Percent_Identity=26.0975609756098, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281363477, Length=410, Percent_Identity=26.0975609756098, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41227; Mature: 41227

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50975 ATP_GRASP ; PS00063 ALDOKETO_REDUCTASE_3 ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPVFSVDDAVKAAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSLEQVREYANQILGMQLVTHQTGPEGQKVNRLLIEEGADIKKELYVGLVIDRVSQK
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCE
IVVMASSEGGMDVEEVAEKTPELIHKIAVDPATGLKDAEADELATKIGVPAASLPQARAI
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQGLYKAFWETDASLAEINPLILTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCHHHCCCEEEECCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEVEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHCCCCCCCCEEECCCCCCHHHHHH
AFKIMLKNPNLTAILVNIFGGIMRCDVIAEGVIAASKAVSLKVPLVVRMKGTNEDLGKKM
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCHHHHHHH
LAESGLPIIAADSMEEAAQKVVAAASGKA
HHHCCCCEEEECCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPVFSVDDAVKAAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSLEQVREYANQILGMQLVTHQTGPEGQKVNRLLIEEGADIKKELYVGLVIDRVSQK
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCE
IVVMASSEGGMDVEEVAEKTPELIHKIAVDPATGLKDAEADELATKIGVPAASLPQARAI
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQGLYKAFWETDASLAEINPLILTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCHHHCCCEEEECCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEVEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHCCCCCCCCEEECCCCCCHHHHHH
AFKIMLKNPNLTAILVNIFGGIMRCDVIAEGVIAASKAVSLKVPLVVRMKGTNEDLGKKM
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCHHHHHHH
LAESGLPIIAADSMEEAAQKVVAAASGKA
HHHCCCCEEEECCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA