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The map label for this gene is murB [H]

Identifier: 91785025

GI number: 91785025

Start: 4047134

End: 4048174

Strand: Reverse

Name: murB [H]

Synonym: Bxe_A0755

Alternate gene names: 91785025

Gene position: 4048174-4047134 (Counterclockwise)

Preceding gene: 91785027

Following gene: 91785022

Centisome position: 82.69

GC content: 66.86

Gene sequence:

>1041_bases
ATGTCCCAAACCGAATCCGCCGCGTTCCTTGCCGGCTATCCGCTCAAGGCGCACAACACCTTCGGCTTCGATGTTCGCGC
GCGGTTTGCATGCCGCATCGAGCAGGAAGCGCAATTGATGCCCGCGGTGCGCGATCCGCGCGCGGCCGGCCTGCCGCGCC
TCGTGCTGGGCGGCGGCAGCAATGTCGTCCTGACCGGCGACTTTGGCGGTCTGGTATTGCTGGTCGCGCTGCGGGGCCGC
CGCGTCGTGCGTGAAGACAATGATGCATGGTACGTCGAAGCAGCGGGCGGCGAGCCGTGGCATGAGTTTGTCGGCTGGAC
TTTGTCGCAAGGAATGGCGGGTCTCGAAAACCTCGCGTTGATCCCGGGCACGGTGGGCGCGGCGCCGATCCAGAACATCG
GCGCGTACGGATTGGAGATGTGCGAGCGCTTTGCGTCGCTGCGCGCGGTGGAGTTGACCACGGGCGCGGTGGTCGAGCTG
GATGCGCAGGCGTGCCGCTTCGGCTATCGCGACAGTTTTTTCAAGCGGGAAGGGCGCGACCGTTTCGTGATTACGTCGGT
GACGTTCCGTTTGCCGAAGGTCTGGCAGCCGCGCGCCGGCTATGCGGATCTCGCTCGCGAGTTGGCCGCGAACGGCCATG
CCGGCACGCCGCCGACCGCGCAGGCCATCTTCGATGCGGTGGTGGCGGTGCGGCGCGCCAAACTGCCCGATCCGCTGGAA
CTCGGCAATGCGGGCAGCTTCTTCAAGAATCCGGTGATCGGGCCGGCGCAGTTCGAGGCGCTGAAGCTCAGGGAACCGGA
CGTCGTGTCCTACGTGCAGGCAGACGGGCGGGTGAAACTCGCCGCCGGCTGGCTGATTGACCGATGCGGCTGGAAAGGCC
GCGCGATGGGCGCGGCGGCCGTGCATGAACGGCAGGCGCTGGTGCTGGTGAACCGCGGCGGCGCGAGTGGCGCCGAAGTG
CTGGCACTCGCGAAAGCGATTCAGCGCGATGTGCGTGAGAGGTTTGGGGTGGAACTGGAGCCGGAGCCGGTTTGTTTGTG
A

Upstream 100 bases:

>100_bases
CCAAGGCCGCCGCGCATTGTCGCCCGGCTGGCGCCGCAAGCCGGTTCGATCGGCTGCTTTATTCGTTGTTTCATTCGTGA
GTTCCACCGTTCTCGTTCCG

Downstream 100 bases:

>100_bases
TGACCGGCTGCCGATAAAAAAGGCGCCGGGAGTCTCCTCCCGGCGCCTTTTTGCGTTTTGGCTCTGGCCGAGCCTTGCGG
CGCCTGACTTCGCTTACGCG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSQTESAAFLAGYPLKAHNTFGFDVRARFACRIEQEAQLMPAVRDPRAAGLPRLVLGGGSNVVLTGDFGGLVLLVALRGR
RVVREDNDAWYVEAAGGEPWHEFVGWTLSQGMAGLENLALIPGTVGAAPIQNIGAYGLEMCERFASLRAVELTTGAVVEL
DAQACRFGYRDSFFKREGRDRFVITSVTFRLPKVWQPRAGYADLARELAANGHAGTPPTAQAIFDAVVAVRRAKLPDPLE
LGNAGSFFKNPVIGPAQFEALKLREPDVVSYVQADGRVKLAAGWLIDRCGWKGRAMGAAAVHERQALVLVNRGGASGAEV
LALAKAIQRDVRERFGVELEPEPVCL

Sequences:

>Translated_346_residues
MSQTESAAFLAGYPLKAHNTFGFDVRARFACRIEQEAQLMPAVRDPRAAGLPRLVLGGGSNVVLTGDFGGLVLLVALRGR
RVVREDNDAWYVEAAGGEPWHEFVGWTLSQGMAGLENLALIPGTVGAAPIQNIGAYGLEMCERFASLRAVELTTGAVVEL
DAQACRFGYRDSFFKREGRDRFVITSVTFRLPKVWQPRAGYADLARELAANGHAGTPPTAQAIFDAVVAVRRAKLPDPLE
LGNAGSFFKNPVIGPAQFEALKLREPDVVSYVQADGRVKLAAGWLIDRCGWKGRAMGAAAVHERQALVLVNRGGASGAEV
LALAKAIQRDVRERFGVELEPEPVCL
>Mature_345_residues
SQTESAAFLAGYPLKAHNTFGFDVRARFACRIEQEAQLMPAVRDPRAAGLPRLVLGGGSNVVLTGDFGGLVLLVALRGRR
VVREDNDAWYVEAAGGEPWHEFVGWTLSQGMAGLENLALIPGTVGAAPIQNIGAYGLEMCERFASLRAVELTTGAVVELD
AQACRFGYRDSFFKREGRDRFVITSVTFRLPKVWQPRAGYADLARELAANGHAGTPPTAQAIFDAVVAVRRAKLPDPLEL
GNAGSFFKNPVIGPAQFEALKLREPDVVSYVQADGRVKLAAGWLIDRCGWKGRAMGAAAVHERQALVLVNRGGASGAEVL
ALAKAIQRDVRERFGVELEPEPVCL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=331, Percent_Identity=49.8489425981873, Blast_Score=311, Evalue=4e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37310; Mature: 37179

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTESAAFLAGYPLKAHNTFGFDVRARFACRIEQEAQLMPAVRDPRAAGLPRLVLGGGS
CCCCCCCEEEECCCEECCCCCCCEEEEEEEEEECHHHHHCCCCCCCCCCCCCEEEEECCC
NVVLTGDFGGLVLLVALRGRRVVREDNDAWYVEAAGGEPWHEFVGWTLSQGMAGLENLAL
CEEEEECCCHHHHHHHHHCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHCCEE
IPGTVGAAPIQNIGAYGLEMCERFASLRAVELTTGAVVELDAQACRFGYRDSFFKREGRD
CCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEECCEEEEECHHHHHCCCHHHHHHHCCCC
RFVITSVTFRLPKVWQPRAGYADLARELAANGHAGTPPTAQAIFDAVVAVRRAKLPDPLE
EEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
LGNAGSFFKNPVIGPAQFEALKLREPDVVSYVQADGRVKLAAGWLIDRCGWKGRAMGAAA
CCCCCCHHCCCCCCCCCHHEEECCCCCHHHHEECCCEEEEEECHHHHHCCCCCCCCCHHH
VHERQALVLVNRGGASGAEVLALAKAIQRDVRERFGVELEPEPVCL
HHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SQTESAAFLAGYPLKAHNTFGFDVRARFACRIEQEAQLMPAVRDPRAAGLPRLVLGGGS
CCCCCCEEEECCCEECCCCCCCEEEEEEEEEECHHHHHCCCCCCCCCCCCCEEEEECCC
NVVLTGDFGGLVLLVALRGRRVVREDNDAWYVEAAGGEPWHEFVGWTLSQGMAGLENLAL
CEEEEECCCHHHHHHHHHCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHCCEE
IPGTVGAAPIQNIGAYGLEMCERFASLRAVELTTGAVVELDAQACRFGYRDSFFKREGRD
CCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEECCEEEEECHHHHHCCCHHHHHHHCCCC
RFVITSVTFRLPKVWQPRAGYADLARELAANGHAGTPPTAQAIFDAVVAVRRAKLPDPLE
EEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
LGNAGSFFKNPVIGPAQFEALKLREPDVVSYVQADGRVKLAAGWLIDRCGWKGRAMGAAA
CCCCCCHHCCCCCCCCCHHEEECCCCCHHHHEECCCEEEEEECHHHHHCCCCCCCCCHHH
VHERQALVLVNRGGASGAEVLALAKAIQRDVRERFGVELEPEPVCL
HHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA