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The map label for this gene is ispH [H]

Identifier: 91784960

GI number: 91784960

Start: 3971420

End: 3972379

Strand: Reverse

Name: ispH [H]

Synonym: Bxe_A0820

Alternate gene names: 91784960

Gene position: 3972379-3971420 (Counterclockwise)

Preceding gene: 91784961

Following gene: 91784959

Centisome position: 81.14

GC content: 63.33

Gene sequence:

>960_bases
ATGAGCATGACGGATACGACTCTTGCTGAAACCGAGATCCTGCTAGCGCAGCCGCGCGGGTTCTGTGCCGGTGTCGACCG
GGCGATCGAGATCGTAGAGCGGGCCATCAAGCTGCACGGCTCGCCGATCTACGTGCGTCACGAAATCGTCCATAACGCGT
ACGTGGTCGAGGATCTGCGCAAGAAGGGTGCGATCTTCATCGAGCGGCTCGAAGAAGTGCCGCCCGGCAACACGGTTATT
TTCAGCGCGCACGGCGTGTCGAAGGCAGTGCGTTCCGAGGCCGAGATTCGCGGGCTGCGGGTGTACGACGCCACGTGCCC
GCTCGTGACCAAGGTGCATATCGAGGTCGCGAAGATGCGCCAGGACGGCTTCGACATCGTCATGATCGGCCACAAGGGCC
ATCCCGAAGTCGAAGGCACGATGGGCCAGGCGGGCGAGGGCATGCATCTGGTGGAAGACATCGAAGACGTACAGGCCTTG
CAACTGGCCGATCCCGAGCGGATTGCATTCGTCACGCAAACCACCCTGTCGGTCGACGACGCAGCCCAGATCATTGCCGC
TCTGAAGGCCAAATATCCGTCCATCCGCGAGCCGAAAAAGCAGGATATCTGCTACGCCACGCAAAACCGCCAGGACGCGG
TGAAGTTCATGGCGCCGCAATGCGACGTCGTGATCGTGGTCGGCAGCCCGAACAGCTCGAACTCCAACCGGCTGCGCGAG
CTGGCCGAGAAGCTCGGCGTGCCTGCCTATATGGTGGACTCGCCCGATCAGATCGATCCGGTCTGGGTCGAAGGCAAACG
CCGCATCGGCGTAACGGCCGGCGCCTCGGCGCCGGAAGTGCTGGCGCAGGCGGTGATCGCCCGCCTGCGTGAGCTCGGCG
TGCGCAATGTGCGCGCGCTCGACGGCATCGAGGAAAACATTGCGTTTCCGCTACCGCGCGGTTTGGGTCTGCCCGCCTGA

Upstream 100 bases:

>100_bases
TGAAAGAAGTCGGTGAAACGTCGGCCCTGTTCGACTTCAACCACCCGCTTGCCGGCCAGGCGCTGGCGTTTGAAGTGAAA
ATCATTGGGATTCTGTAAAC

Downstream 100 bases:

>100_bases
CAATTTGCTGACTGCTGAAAGAAAAGCGCGCCCGAGGGCGCGCTTTTTTCATATCTGGCGTCCAGCAACTGCGGCTAAAA
TAAAGTGCCAGATCATCATG

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSMTDTTLAETEILLAQPRGFCAGVDRAIEIVERAIKLHGSPIYVRHEIVHNAYVVEDLRKKGAIFIERLEEVPPGNTVI
FSAHGVSKAVRSEAEIRGLRVYDATCPLVTKVHIEVAKMRQDGFDIVMIGHKGHPEVEGTMGQAGEGMHLVEDIEDVQAL
QLADPERIAFVTQTTLSVDDAAQIIAALKAKYPSIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNSNRLRE
LAEKLGVPAYMVDSPDQIDPVWVEGKRRIGVTAGASAPEVLAQAVIARLRELGVRNVRALDGIEENIAFPLPRGLGLPA

Sequences:

>Translated_319_residues
MSMTDTTLAETEILLAQPRGFCAGVDRAIEIVERAIKLHGSPIYVRHEIVHNAYVVEDLRKKGAIFIERLEEVPPGNTVI
FSAHGVSKAVRSEAEIRGLRVYDATCPLVTKVHIEVAKMRQDGFDIVMIGHKGHPEVEGTMGQAGEGMHLVEDIEDVQAL
QLADPERIAFVTQTTLSVDDAAQIIAALKAKYPSIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNSNRLRE
LAEKLGVPAYMVDSPDQIDPVWVEGKRRIGVTAGASAPEVLAQAVIARLRELGVRNVRALDGIEENIAFPLPRGLGLPA
>Mature_318_residues
SMTDTTLAETEILLAQPRGFCAGVDRAIEIVERAIKLHGSPIYVRHEIVHNAYVVEDLRKKGAIFIERLEEVPPGNTVIF
SAHGVSKAVRSEAEIRGLRVYDATCPLVTKVHIEVAKMRQDGFDIVMIGHKGHPEVEGTMGQAGEGMHLVEDIEDVQALQ
LADPERIAFVTQTTLSVDDAAQIIAALKAKYPSIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNSNRLREL
AEKLGVPAYMVDSPDQIDPVWVEGKRRIGVTAGASAPEVLAQAVIARLRELGVRNVRALDGIEENIAFPLPRGLGLPA

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=307, Percent_Identity=58.3061889250814, Blast_Score=368, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 34808; Mature: 34676

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTDTTLAETEILLAQPRGFCAGVDRAIEIVERAIKLHGSPIYVRHEIVHNAYVVEDLR
CCCCCCHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHH
KKGAIFIERLEEVPPGNTVIFSAHGVSKAVRSEAEIRGLRVYDATCPLVTKVHIEVAKMR
HCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCEEEEECCCCEEHHHHHHHHHHH
QDGFDIVMIGHKGHPEVEGTMGQAGEGMHLVEDIEDVQALQLADPERIAFVTQTTLSVDD
CCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHH
AAQIIAALKAKYPSIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNSNRLRE
HHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
LAEKLGVPAYMVDSPDQIDPVWVEGKRRIGVTAGASAPEVLAQAVIARLRELGVRNVRAL
HHHHHCCCEEEECCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHH
DGIEENIAFPLPRGLGLPA
CCCHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SMTDTTLAETEILLAQPRGFCAGVDRAIEIVERAIKLHGSPIYVRHEIVHNAYVVEDLR
CCCCCHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHH
KKGAIFIERLEEVPPGNTVIFSAHGVSKAVRSEAEIRGLRVYDATCPLVTKVHIEVAKMR
HCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCEEEEECCCCEEHHHHHHHHHHH
QDGFDIVMIGHKGHPEVEGTMGQAGEGMHLVEDIEDVQALQLADPERIAFVTQTTLSVDD
CCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHH
AAQIIAALKAKYPSIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNSNRLRE
HHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
LAEKLGVPAYMVDSPDQIDPVWVEGKRRIGVTAGASAPEVLAQAVIARLRELGVRNVRAL
HHHHHCCCEEEECCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHH
DGIEENIAFPLPRGLGLPA
CCCHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA