Click here to switch to the map view.

The map label for this gene is tdcB [H]

Identifier: 91784905

GI number: 91784905

Start: 3907304

End: 3908269

Strand: Reverse

Name: tdcB [H]

Synonym: Bxe_A0886

Alternate gene names: 91784905

Gene position: 3908269-3907304 (Counterclockwise)

Preceding gene: 91784906

Following gene: 91784902

Centisome position: 79.83

GC content: 64.8

Gene sequence:

>966_bases
ATGCAAGCGCTTCCCGCTCCCACTTTCGACGACGTACTCGACGCCGCTGCGCGTCTTGAAGGCGTCGCCCACCGCACTCC
CGTGCTGACCTCGAGCACGTTTGACGAACGAACGGGCGCGTCGGTGTTCTTCAAGTGCGAGAATTTTCAGCGCATGGGCG
CCTTCAAGTTTCGCGGTGCCTATAACGCGATCTCGCATTTCGACGCGGAGCAACGCAAAGCCGGCGTGCTGACGTATTCG
TCGGGTAACCACGCGCAGGCAATTGCATTGTCGGCGCGGCTTGCCGGCATTCGCGCGACGATCATCATGCCGCACGACGC
ACCGGCCGCCAAAGTCGCGGCAACCAAAGGCTACGGCGGCGAAGTGATCACCTACGACCGCTACACCGAGAACCGCGAAG
AGATCGGCCGGCGTCTCGCCGGAGAGCGTGGCATGACGCTGATTCCACCATACGATCATCCACATGTGATCGCCGGGCAG
GGCACGGCGGTGAAAGAACTGATCGAGGAAACCGGCCCGCTCGACATGCTGTTCGTGTGCCTCGGCGGCGGCGGGCTGAT
CAGCGGCAGCGCGTTGTCCGCCGCGGCGTTGAGCCCGGCGTGCACGGTGATCGGCGTCGAGCCGGAGGCGGGTAACGACG
GCCAGCAGTCGCTGGCGCGCGGCGAGATCGTGCATATCGACACGCCGCGCACGATCGCCGACGGCGCCGCCTCCACGCAT
CTGGGCGACTACACGTTTGCGATCATCCGCAAGCTGGTTGCGCGGATCGAAACGGTCAGCGACGGGCAACTGATCGACAC
GATGCGCTTTTTCGCGCAGCGCATGAAGATCGTGGTCGAGCCGACGGGTTGTCTCGCCGCGGCGGCGGTGCTCAACGGCA
TCGTGCCGGTGAAGGGCAAGCGTGTCGGCGTGGTGGTCAGCGGCGGCAACGTCGATCTGGAAAAGCTCGCGCAGTATCTC
GCCTGA

Upstream 100 bases:

>100_bases
GGGTTACGCCGTTTGTATTTTTGCTGCGCGTTCAACGTTCCAAACCTTCGTCGAAGCTGGGAGAATGGCTGTTTCGCCAC
CGCTCTGGAGAGTTTCGCCG

Downstream 100 bases:

>100_bases
TACGTCGGGGCGGCTGTTGTTGCGCTCGCGGGACCCTATGACCTGATATGTGACGCTTGATCGAACACGGCTCGAACGGC
GCGAGCCGTTGTTATATCAG

Product: serine/threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MQALPAPTFDDVLDAAARLEGVAHRTPVLTSSTFDERTGASVFFKCENFQRMGAFKFRGAYNAISHFDAEQRKAGVLTYS
SGNHAQAIALSARLAGIRATIIMPHDAPAAKVAATKGYGGEVITYDRYTENREEIGRRLAGERGMTLIPPYDHPHVIAGQ
GTAVKELIEETGPLDMLFVCLGGGGLISGSALSAAALSPACTVIGVEPEAGNDGQQSLARGEIVHIDTPRTIADGAASTH
LGDYTFAIIRKLVARIETVSDGQLIDTMRFFAQRMKIVVEPTGCLAAAAVLNGIVPVKGKRVGVVVSGGNVDLEKLAQYL
A

Sequences:

>Translated_321_residues
MQALPAPTFDDVLDAAARLEGVAHRTPVLTSSTFDERTGASVFFKCENFQRMGAFKFRGAYNAISHFDAEQRKAGVLTYS
SGNHAQAIALSARLAGIRATIIMPHDAPAAKVAATKGYGGEVITYDRYTENREEIGRRLAGERGMTLIPPYDHPHVIAGQ
GTAVKELIEETGPLDMLFVCLGGGGLISGSALSAAALSPACTVIGVEPEAGNDGQQSLARGEIVHIDTPRTIADGAASTH
LGDYTFAIIRKLVARIETVSDGQLIDTMRFFAQRMKIVVEPTGCLAAAAVLNGIVPVKGKRVGVVVSGGNVDLEKLAQYL
A
>Mature_321_residues
MQALPAPTFDDVLDAAARLEGVAHRTPVLTSSTFDERTGASVFFKCENFQRMGAFKFRGAYNAISHFDAEQRKAGVLTYS
SGNHAQAIALSARLAGIRATIIMPHDAPAAKVAATKGYGGEVITYDRYTENREEIGRRLAGERGMTLIPPYDHPHVIAGQ
GTAVKELIEETGPLDMLFVCLGGGGLISGSALSAAALSPACTVIGVEPEAGNDGQQSLARGEIVHIDTPRTIADGAASTH
LGDYTFAIIRKLVARIETVSDGQLIDTMRFFAQRMKIVVEPTGCLAAAAVLNGIVPVKGKRVGVVVSGGNVDLEKLAQYL
A

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=313, Percent_Identity=40.2555910543131, Blast_Score=223, Evalue=1e-58,
Organism=Homo sapiens, GI19923959, Length=299, Percent_Identity=27.4247491638796, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI33469958, Length=315, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI295821202, Length=199, Percent_Identity=29.6482412060301, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI295821200, Length=199, Percent_Identity=29.6482412060301, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4557415, Length=199, Percent_Identity=29.6482412060301, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789505, Length=314, Percent_Identity=40.1273885350318, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1790207, Length=298, Percent_Identity=35.5704697986577, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI2367138, Length=203, Percent_Identity=28.0788177339901, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508781, Length=309, Percent_Identity=32.6860841423948, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71991565, Length=305, Percent_Identity=32.1311475409836, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17537387, Length=305, Percent_Identity=33.1147540983607, Blast_Score=126, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322631, Length=315, Percent_Identity=62.2222222222222, Blast_Score=383, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6320930, Length=305, Percent_Identity=32.7868852459016, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6319788, Length=286, Percent_Identity=23.4265734265734, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355833, Length=306, Percent_Identity=34.3137254901961, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24645328, Length=211, Percent_Identity=33.6492890995261, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 33908; Mature: 33908

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALPAPTFDDVLDAAARLEGVAHRTPVLTSSTFDERTGASVFFKCENFQRMGAFKFRGA
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCCHHCCCEEECCH
YNAISHFDAEQRKAGVLTYSSGNHAQAIALSARLAGIRATIIMPHDAPAAKVAATKGYGG
HHHHHHCCHHHHHCCEEEECCCCCCEEEEEHHHHCCEEEEEEECCCCCCHHEEEECCCCC
EVITYDRYTENREEIGRRLAGERGMTLIPPYDHPHVIAGQGTAVKELIEETGPLDMLFVC
CEEEECCCCCCHHHHHHHHHCCCCCEEECCCCCCEEEECCCHHHHHHHHHCCCCEEEEEE
LGGGGLISGSALSAAALSPACTVIGVEPEAGNDGQQSLARGEIVHIDTPRTIADGAASTH
ECCCCEECCCHHHHHHCCCCEEEEEECCCCCCCHHHHHHCCCEEEECCCCHHHCCCCCCC
LGDYTFAIIRKLVARIETVSDGQLIDTMRFFAQRMKIVVEPTGCLAAAAVLNGIVPVKGK
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCCC
RVGVVVSGGNVDLEKLAQYLA
EEEEEEECCCCCHHHHHHHHC
>Mature Secondary Structure
MQALPAPTFDDVLDAAARLEGVAHRTPVLTSSTFDERTGASVFFKCENFQRMGAFKFRGA
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCCHHCCCEEECCH
YNAISHFDAEQRKAGVLTYSSGNHAQAIALSARLAGIRATIIMPHDAPAAKVAATKGYGG
HHHHHHCCHHHHHCCEEEECCCCCCEEEEEHHHHCCEEEEEEECCCCCCHHEEEECCCCC
EVITYDRYTENREEIGRRLAGERGMTLIPPYDHPHVIAGQGTAVKELIEETGPLDMLFVC
CEEEECCCCCCHHHHHHHHHCCCCCEEECCCCCCEEEECCCHHHHHHHHHCCCCEEEEEE
LGGGGLISGSALSAAALSPACTVIGVEPEAGNDGQQSLARGEIVHIDTPRTIADGAASTH
ECCCCEECCCHHHHHHCCCCEEEEEECCCCCCCHHHHHHCCCEEEECCCCHHHCCCCCCC
LGDYTFAIIRKLVARIETVSDGQLIDTMRFFAQRMKIVVEPTGCLAAAAVLNGIVPVKGK
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCCC
RVGVVVSGGNVDLEKLAQYLA
EEEEEEECCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA