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The map label for this gene is hutH [H]

Identifier: 91784859

GI number: 91784859

Start: 3859202

End: 3860797

Strand: Reverse

Name: hutH [H]

Synonym: Bxe_A0933

Alternate gene names: 91784859

Gene position: 3860797-3859202 (Counterclockwise)

Preceding gene: 91784860

Following gene: 91784858

Centisome position: 78.86

GC content: 66.17

Gene sequence:

>1596_bases
ATGGCCGAACATGATCTGATCGATGTACCGGAGGCGGGCGCAAACGTGAACACGGCAGCCGTGGTAATAGGCGGGCGCAA
GCTGACGATCGAAGAGGTCGTCGCGATTGCGCGGCACCGCGCGCCGGTCGCCTTGAGCGCCGATCCGGCATGGCGCGCGC
GCATCCAGCGCGGCGCGGATTTTCTGCGCCGGCATCTGGCCGCGGGCGCGACCGTGTACGGCGTCAACACCGGTTACGGC
GATGCCTGCGTGGTCGACGTGCCGATGGAACTGGTCGAAGCACTGCCGCTGCAACTCACGCGCTATCACGGCTGCGGCAT
GGGCCAGTATCTCGACGAAGCGCAAACGCTCGCGGTGATCGCCGCGCGGCTCAACTCGCTCGCATACGGTTTTTCGGGCG
TGCGTCCGGTGTTGCTCGAACGTCTCGCCGATCTGGTCAATCATCGCGTGTTGCCGCGCATTCCGTCGGAAGGCTCGGTC
GGCGCGAGCGGCGATCTCACGCCGCTTTCGTATGTGGCCGCCGCGCTCGCCGGTGAGCGCGACGTAATGTTCGAAGGGCA
GTTGCGCAACGTGCGCGAGGTGTGGACCGAACTCGGTCAAACGCCGCTCACGCTCGCGCCGAAAGAAGGGCTTGCGCTGA
TGAACGGCACCGCCGTGATGACGGGTCTCGCCTGTCTCGCGTTTGCGCGCGCCGATCATCTCACGCGGCTCACCGCGCGC
CTGACGGCGCTGTGCACGGTCGCGCTCGACGGCCGTGCCGCGCATTTCGACGCAATGCTGTTCGAGGTGAAGCCGCACGC
CGGCCAGGCCGAAGCGGCGGCATGGATCCGCGACGACCTGGCCGGGCGCGACGACACGCCGGGCCACCGTTTGCAGGACC
GCTATTCGATTCGCTGCGCGCCGCACGTGATCGGCGTGGCGCGCGACGCGCTTTCGTGGGTACGCCGCGACATCGAGAAC
GAACTGAACAGCGCGAACGACAACCCGCTGATCGATCCGGACAACGAACGCGTGCTGCACGGCGGCAACTTCTACGGCGG
TCATATCGCTTTCGCGATGGACTCGCTGAAGGTCGCGGTCGCCAACCTCGCCGATCTGATGGACCGGCAACTGGCGCTTC
TCGTCGACGTCAATTTCAATAACGGCTTGCCGCGCAATCTGTCGGGCGCTACGTCCGCGCGCGCCGCGATCAATCACGGG
TTCAAGGCGGTGCAGATTTCCTCATCCGCATGGACCGCCGAAGCATTGAAGAACACCATGCCCGCCAGCGTTTTCTCGCG
CTCCACCGAGGCGCACAACCAGGACAAGGTCAGCATGGGCACGATCGCCGCGCGCGACTGCCTGCGCGTGCTGGAACTGA
CCGAACAGGTGGCGGCAGCGCATACGCTCGCAACCGTGCAAGCTGCCCGTCTGCGATTGAAGATCGATAGCGGAACACCG
GTTCCCGCGCCGCTGCGAACGTTCATGGAGAGCGTGAGCGCGCAGTCGCCGTTCGTGGACGAAGACCGCGCGCTCGAACA
CGAACTGCGCGCCCTGACCGCGCGCATTGCCGCGTGCGATCTGCTGCGGGACTATCGCGGAGGACCGGACGCATGA

Upstream 100 bases:

>100_bases
GCGCAGCGTTACGCCGTGCGTCTCGAACACTATTGCCGCAAGGCACCTTATCAATGGTTCAACTTCTTCGATTTCTGGGC
CAGCCCCAAGCGAGGCGCGA

Downstream 100 bases:

>100_bases
CAGGTTCCCGCAAAGTGCTGAGCGCGAGCGCGACGGTGGAAGTGCCGTTCCACGATGTCGATGCGATGAACGTGTGCTGG
CATGGGCACTATCTGAAGTA

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MAEHDLIDVPEAGANVNTAAVVIGGRKLTIEEVVAIARHRAPVALSADPAWRARIQRGADFLRRHLAAGATVYGVNTGYG
DACVVDVPMELVEALPLQLTRYHGCGMGQYLDEAQTLAVIAARLNSLAYGFSGVRPVLLERLADLVNHRVLPRIPSEGSV
GASGDLTPLSYVAAALAGERDVMFEGQLRNVREVWTELGQTPLTLAPKEGLALMNGTAVMTGLACLAFARADHLTRLTAR
LTALCTVALDGRAAHFDAMLFEVKPHAGQAEAAAWIRDDLAGRDDTPGHRLQDRYSIRCAPHVIGVARDALSWVRRDIEN
ELNSANDNPLIDPDNERVLHGGNFYGGHIAFAMDSLKVAVANLADLMDRQLALLVDVNFNNGLPRNLSGATSARAAINHG
FKAVQISSSAWTAEALKNTMPASVFSRSTEAHNQDKVSMGTIAARDCLRVLELTEQVAAAHTLATVQAARLRLKIDSGTP
VPAPLRTFMESVSAQSPFVDEDRALEHELRALTARIAACDLLRDYRGGPDA

Sequences:

>Translated_531_residues
MAEHDLIDVPEAGANVNTAAVVIGGRKLTIEEVVAIARHRAPVALSADPAWRARIQRGADFLRRHLAAGATVYGVNTGYG
DACVVDVPMELVEALPLQLTRYHGCGMGQYLDEAQTLAVIAARLNSLAYGFSGVRPVLLERLADLVNHRVLPRIPSEGSV
GASGDLTPLSYVAAALAGERDVMFEGQLRNVREVWTELGQTPLTLAPKEGLALMNGTAVMTGLACLAFARADHLTRLTAR
LTALCTVALDGRAAHFDAMLFEVKPHAGQAEAAAWIRDDLAGRDDTPGHRLQDRYSIRCAPHVIGVARDALSWVRRDIEN
ELNSANDNPLIDPDNERVLHGGNFYGGHIAFAMDSLKVAVANLADLMDRQLALLVDVNFNNGLPRNLSGATSARAAINHG
FKAVQISSSAWTAEALKNTMPASVFSRSTEAHNQDKVSMGTIAARDCLRVLELTEQVAAAHTLATVQAARLRLKIDSGTP
VPAPLRTFMESVSAQSPFVDEDRALEHELRALTARIAACDLLRDYRGGPDA
>Mature_530_residues
AEHDLIDVPEAGANVNTAAVVIGGRKLTIEEVVAIARHRAPVALSADPAWRARIQRGADFLRRHLAAGATVYGVNTGYGD
ACVVDVPMELVEALPLQLTRYHGCGMGQYLDEAQTLAVIAARLNSLAYGFSGVRPVLLERLADLVNHRVLPRIPSEGSVG
ASGDLTPLSYVAAALAGERDVMFEGQLRNVREVWTELGQTPLTLAPKEGLALMNGTAVMTGLACLAFARADHLTRLTARL
TALCTVALDGRAAHFDAMLFEVKPHAGQAEAAAWIRDDLAGRDDTPGHRLQDRYSIRCAPHVIGVARDALSWVRRDIENE
LNSANDNPLIDPDNERVLHGGNFYGGHIAFAMDSLKVAVANLADLMDRQLALLVDVNFNNGLPRNLSGATSARAAINHGF
KAVQISSSAWTAEALKNTMPASVFSRSTEAHNQDKVSMGTIAARDCLRVLELTEQVAAAHTLATVQAARLRLKIDSGTPV
PAPLRTFMESVSAQSPFVDEDRALEHELRALTARIAACDLLRDYRGGPDA

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=477, Percent_Identity=33.7526205450734, Blast_Score=260, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17567831, Length=514, Percent_Identity=32.8793774319066, Blast_Score=236, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 57033; Mature: 56901

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00488 PAL_HISTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHDLIDVPEAGANVNTAAVVIGGRKLTIEEVVAIARHRAPVALSADPAWRARIQRGAD
CCCCCCCCCCCCCCCCCEEEEEECCCEECHHHHHHHHHCCCCEEECCCHHHHHHHHHHHH
FLRRHLAAGATVYGVNTGYGDACVVDVPMELVEALPLQLTRYHGCGMGQYLDEAQTLAVI
HHHHHHHCCCEEEECCCCCCCEEEEECCHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHH
AARLNSLAYGFSGVRPVLLERLADLVNHRVLPRIPSEGSVGASGDLTPLSYVAAALAGER
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
DVMFEGQLRNVREVWTELGQTPLTLAPKEGLALMNGTAVMTGLACLAFARADHLTRLTAR
CEEECCHHHHHHHHHHHHCCCCEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LTALCTVALDGRAAHFDAMLFEVKPHAGQAEAAAWIRDDLAGRDDTPGHRLQDRYSIRCA
HHHHHHHEECCCCHHEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
PHVIGVARDALSWVRRDIENELNSANDNPLIDPDNERVLHGGNFYGGHIAFAMDSLKVAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEECCCCEEHHHHHHHHH
ANLADLMDRQLALLVDVNFNNGLPRNLSGATSARAAINHGFKAVQISSSAWTAEALKNTM
HHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHCC
PASVFSRSTEAHNQDKVSMGTIAARDCLRVLELTEQVAAAHTLATVQAARLRLKIDSGTP
CHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCC
VPAPLRTFMESVSAQSPFVDEDRALEHELRALTARIAACDLLRDYRGGPDA
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AEHDLIDVPEAGANVNTAAVVIGGRKLTIEEVVAIARHRAPVALSADPAWRARIQRGAD
CCCCCCCCCCCCCCCCEEEEEECCCEECHHHHHHHHHCCCCEEECCCHHHHHHHHHHHH
FLRRHLAAGATVYGVNTGYGDACVVDVPMELVEALPLQLTRYHGCGMGQYLDEAQTLAVI
HHHHHHHCCCEEEECCCCCCCEEEEECCHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHH
AARLNSLAYGFSGVRPVLLERLADLVNHRVLPRIPSEGSVGASGDLTPLSYVAAALAGER
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
DVMFEGQLRNVREVWTELGQTPLTLAPKEGLALMNGTAVMTGLACLAFARADHLTRLTAR
CEEECCHHHHHHHHHHHHCCCCEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LTALCTVALDGRAAHFDAMLFEVKPHAGQAEAAAWIRDDLAGRDDTPGHRLQDRYSIRCA
HHHHHHHEECCCCHHEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
PHVIGVARDALSWVRRDIENELNSANDNPLIDPDNERVLHGGNFYGGHIAFAMDSLKVAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEECCCCEEHHHHHHHHH
ANLADLMDRQLALLVDVNFNNGLPRNLSGATSARAAINHGFKAVQISSSAWTAEALKNTM
HHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHCC
PASVFSRSTEAHNQDKVSMGTIAARDCLRVLELTEQVAAAHTLATVQAARLRLKIDSGTP
CHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCC
VPAPLRTFMESVSAQSPFVDEDRALEHELRALTARIAACDLLRDYRGGPDA
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA