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The map label for this gene is czcD [H]

Identifier: 91784831

GI number: 91784831

Start: 3825219

End: 3826289

Strand: Reverse

Name: czcD [H]

Synonym: Bxe_A0961

Alternate gene names: 91784831

Gene position: 3826289-3825219 (Counterclockwise)

Preceding gene: 91784832

Following gene: 91784830

Centisome position: 78.15

GC content: 67.69

Gene sequence:

>1071_bases
ATGAATAAACCGGATATCCCGAACGGAACCGCAGCAGATCACGAGCACGCGCCCGCCGGGCACGAGCGCGATCGGGCGTC
GGGCGGCTGCGGTCAGGATCACAGCAGTCATGGCCACATTGACCACAACCACGGCAGTCACAACCACGGCAGTCACAACC
ACGCCGGCCATCACCACGCTCACGCCCCTGTCGCAGGCCACGGCCGCTCGTTCGCTCTCGCCGTCGTGTTGAACATCGCC
ATCGTGGTGGCCCAGGCGGTCTACGGCGTGATCGCCCATTCCACCGCGCTGCTCGCCGACGCCGGCCACAATCTCTCCGA
CGTCCTCGGCCTGCTGCTCGCCTGGGGCGCGGCCTGGCTTGCCACGCGCCGTCCGTCGGCGCGCTATACGTTCGGTTATG
GCAGCTCGTCGATCCTGGCCTCGCTCGTCAATGCCGGGCTGTTGCTGTTCGCGTGCGGCGTGATCGTCGCTGAAGCAATC
GGGCGGCTGATCAACCCGGCGCCTGTGGCGGGGCTCGCGGTGTTCGTCGTGGCAATGGGCGGCGTGGTCGTCAACGGCAT
TTCCGCGTGGCTTTTCATGCGCGGGCAGCAGGAGGACCTGAACATCCGCGGCGCGTTCCTGCACATGGCGGCCGATGCCG
GCATCTCCGCAGCGGTCGCGGTGAGTGGTCTCGTGATCCTCTATACCAGCTGGACGTGGCTCGACCCGGTGATGAGCCTG
CTCGTGGTGGCGGTCGTGGTGGCCGGCACCTGGGGCCTGCTGCGCGACTCGGTGCGCCTCGCGCTCGACGCCGTGCCGCC
CGGCGTCGATCTGCAAGGCATCCGCGACTATCTGGCGGGGCAGCCCGGCGTGGTCGACGTGCACGATCTGCACGTGTGGG
CCTTGTCGACCACCGGCAATGCGCTCAGCGCGCATCTGGTGATGCCGGCGGGCCATCCCGGCGACGAGTCGCTCGACGGT
ATCGTCGTCACGCTGCGCGAACGTTTTTCGATGCAGCATGCGACGCTGCAAGTCGACCTCGGCACCACAGACCACCGCTG
CGCGATGGATCATGCGTCGCACGCGCATTGA

Upstream 100 bases:

>100_bases
AGGTTTTCTATCTCGCCGCCGATCGCCATATCAGCGCGATGCTGGCGGGCATGCTCGAACACGTGGCCGAACCGGCCGGC
AACGATTCCCAGGACGCGTC

Downstream 100 bases:

>100_bases
AGCTGGGCGGGACGCGCGGCAAGTCACGGCACCGGCACAACGCGGTCACCACATGGTCACCACGATGCCACGCCGGTGCC
GCGATTGATGCAACGCAACC

Product: cation efflux pump CDF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MNKPDIPNGTAADHEHAPAGHERDRASGGCGQDHSSHGHIDHNHGSHNHGSHNHAGHHHAHAPVAGHGRSFALAVVLNIA
IVVAQAVYGVIAHSTALLADAGHNLSDVLGLLLAWGAAWLATRRPSARYTFGYGSSSILASLVNAGLLLFACGVIVAEAI
GRLINPAPVAGLAVFVVAMGGVVVNGISAWLFMRGQQEDLNIRGAFLHMAADAGISAAVAVSGLVILYTSWTWLDPVMSL
LVVAVVVAGTWGLLRDSVRLALDAVPPGVDLQGIRDYLAGQPGVVDVHDLHVWALSTTGNALSAHLVMPAGHPGDESLDG
IVVTLRERFSMQHATLQVDLGTTDHRCAMDHASHAH

Sequences:

>Translated_356_residues
MNKPDIPNGTAADHEHAPAGHERDRASGGCGQDHSSHGHIDHNHGSHNHGSHNHAGHHHAHAPVAGHGRSFALAVVLNIA
IVVAQAVYGVIAHSTALLADAGHNLSDVLGLLLAWGAAWLATRRPSARYTFGYGSSSILASLVNAGLLLFACGVIVAEAI
GRLINPAPVAGLAVFVVAMGGVVVNGISAWLFMRGQQEDLNIRGAFLHMAADAGISAAVAVSGLVILYTSWTWLDPVMSL
LVVAVVVAGTWGLLRDSVRLALDAVPPGVDLQGIRDYLAGQPGVVDVHDLHVWALSTTGNALSAHLVMPAGHPGDESLDG
IVVTLRERFSMQHATLQVDLGTTDHRCAMDHASHAH
>Mature_356_residues
MNKPDIPNGTAADHEHAPAGHERDRASGGCGQDHSSHGHIDHNHGSHNHGSHNHAGHHHAHAPVAGHGRSFALAVVLNIA
IVVAQAVYGVIAHSTALLADAGHNLSDVLGLLLAWGAAWLATRRPSARYTFGYGSSSILASLVNAGLLLFACGVIVAEAI
GRLINPAPVAGLAVFVVAMGGVVVNGISAWLFMRGQQEDLNIRGAFLHMAADAGISAAVAVSGLVILYTSWTWLDPVMSL
LVVAVVVAGTWGLLRDSVRLALDAVPPGVDLQGIRDYLAGQPGVVDVHDLHVWALSTTGNALSAHLVMPAGHPGDESLDG
IVVTLRERFSMQHATLQVDLGTTDHRCAMDHASHAH

Specific function: Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=313, Percent_Identity=25.8785942492013, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI64762489, Length=269, Percent_Identity=28.2527881040892, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI289803013, Length=269, Percent_Identity=28.2527881040892, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI289803009, Length=269, Percent_Identity=28.2527881040892, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI289803007, Length=269, Percent_Identity=28.2527881040892, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI289803003, Length=269, Percent_Identity=28.2527881040892, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI21361112, Length=297, Percent_Identity=27.9461279461279, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI21359890, Length=314, Percent_Identity=25.1592356687898, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI14210520, Length=223, Percent_Identity=25.5605381165919, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI52351208, Length=157, Percent_Identity=26.1146496815287, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1786966, Length=279, Percent_Identity=34.4086021505376, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI193210990, Length=313, Percent_Identity=28.4345047923323, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17555794, Length=308, Percent_Identity=28.5714285714286, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17555796, Length=282, Percent_Identity=28.7234042553192, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32564488, Length=303, Percent_Identity=24.4224422442244, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17550440, Length=123, Percent_Identity=30.0813008130081, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17550442, Length=123, Percent_Identity=30.0813008130081, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323899, Length=120, Percent_Identity=34.1666666666667, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324892, Length=127, Percent_Identity=33.8582677165354, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320411, Length=176, Percent_Identity=34.6590909090909, Blast_Score=72, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24583858, Length=343, Percent_Identity=23.0320699708455, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24656728, Length=282, Percent_Identity=26.5957446808511, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24656724, Length=282, Percent_Identity=26.5957446808511, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24656720, Length=282, Percent_Identity=26.5957446808511, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24656715, Length=282, Percent_Identity=26.5957446808511, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357035, Length=282, Percent_Identity=26.5957446808511, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28574430, Length=142, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584409, Length=142, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24645863, Length=109, Percent_Identity=31.1926605504587, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24585900, Length=149, Percent_Identity=26.1744966442953, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24585898, Length=149, Percent_Identity=26.1744966442953, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24585896, Length=149, Percent_Identity=26.1744966442953, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19921672, Length=149, Percent_Identity=26.1744966442953, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 37098; Mature: 37098

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPDIPNGTAADHEHAPAGHERDRASGGCGQDHSSHGHIDHNHGSHNHGSHNHAGHHHA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HAPVAGHGRSFALAVVLNIAIVVAQAVYGVIAHSTALLADAGHNLSDVLGLLLAWGAAWL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ATRRPSARYTFGYGSSSILASLVNAGLLLFACGVIVAEAIGRLINPAPVAGLAVFVVAMG
HCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GVVVNGISAWLFMRGQQEDLNIRGAFLHMAADAGISAAVAVSGLVILYTSWTWLDPVMSL
HHHHHHHHHHHEECCCCCCCCEEEEEEEEHHCCCCHHHHHHHCEEEEEECHHHHHHHHHH
LVVAVVVAGTWGLLRDSVRLALDAVPPGVDLQGIRDYLAGQPGVVDVHDLHVWALSTTGN
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEEECCCC
ALSAHLVMPAGHPGDESLDGIVVTLRERFSMQHATLQVDLGTTDHRCAMDHASHAH
CEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MNKPDIPNGTAADHEHAPAGHERDRASGGCGQDHSSHGHIDHNHGSHNHGSHNHAGHHHA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HAPVAGHGRSFALAVVLNIAIVVAQAVYGVIAHSTALLADAGHNLSDVLGLLLAWGAAWL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ATRRPSARYTFGYGSSSILASLVNAGLLLFACGVIVAEAIGRLINPAPVAGLAVFVVAMG
HCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GVVVNGISAWLFMRGQQEDLNIRGAFLHMAADAGISAAVAVSGLVILYTSWTWLDPVMSL
HHHHHHHHHHHEECCCCCCCCEEEEEEEEHHCCCCHHHHHHHCEEEEEECHHHHHHHHHH
LVVAVVVAGTWGLLRDSVRLALDAVPPGVDLQGIRDYLAGQPGVVDVHDLHVWALSTTGN
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEEECCCC
ALSAHLVMPAGHPGDESLDGIVVTLRERFSMQHATLQVDLGTTDHRCAMDHASHAH
CEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377; 9099864 [H]