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The map label for this gene is hisC1 [H]

Identifier: 91784815

GI number: 91784815

Start: 3805319

End: 3806431

Strand: Reverse

Name: hisC1 [H]

Synonym: Bxe_A0978

Alternate gene names: 91784815

Gene position: 3806431-3805319 (Counterclockwise)

Preceding gene: 91784816

Following gene: 91784814

Centisome position: 77.75

GC content: 62.17

Gene sequence:

>1113_bases
ATGACAGCGTCTTTCGGTCCTTCCTACGTGCGTGCCATTGCGCCTTACGTCGCGGGTAAACCGATTTCGGAAGTGGCTCG
CGAATTCGATCTGGACGAAAAGACCATCGTGAAACTGGCCTCGAACGAGAATCCGCTCGGCATGCCGGAATCGGCGCAGC
GCGCGATGGCGCAGGCCGCCAGCGAACTGGGCCGCTACCCCGACGCCAACGCGTTCGAACTGAAGGCCGCGCTGAGCAAG
CGCTACGGCGTGCCGGCCGACTGGATCACGCTCGGCAACGGCAGCAACGACATCCTCGAAATCGCCGCACACGCGTTTGT
GGAAAAGGACCAGTCGATCGTCTATGCACAGTACTCGTTCGCGGTTTACGCGTTGGCCACGCAAGGTCTGGGCGCTCGCG
CGATCGTCGTGCCGGCTGTCGGGTACGGTCATGACCTCGGCGCCATGCTCGCGGCGATCACCGACGACACGCGCCTGATT
TTCGTCGCCAATCCGAACAACCCGACCGGTACGTTCATCGAAGGCGCGAAGCTCGAAGCGTTTCTCGACAAGGTGCCGCG
CAACGTGGTCGTCGTGCTCGACGAGGCATACACGGAATATCTGCCGCAGGAGAAGCGCTACGACTCGATCGCGTGGGTGC
GCCGCTATCCGAATCTGCTGGTGTCGCGAACCTTTTCGAAGGCGTTCGGCCTTGCCGGTTTGCGCGTGGGTTTCGCGATC
GCACAGCCTGAATTGACCGATCTGCTGAATCGTCTGCGTCAGCCGTTCAACGTGAACACGCTGGCGCAAGCCGCGGCGAT
CGCCGCGCTGAACGACAGGGCGTTTCTGGAGAAGAGCGCCGTGTTGAACGCGCAAGGCTATCGCCGTTTGACCGAAGCGT
TCGACAAGCTCGGTCTGGAATATGTGCCTTCGGACGGCAACTTCGTGCTGGTACGTGTCGGCAACGACGACGCAGCGGGC
AACCGCGTCAACCTGGCGTTGCTGAAGCAGGGCGTGATCGTGCGGCCGGTCGGCAACTACGGCTTGCCGCAATGGCTGCG
CGTCACGATCGGCCTGCCGGAAGAAAACGAAGCATTCGTTGCGGCGCTCGAAAAAGCGCTCGCCACCGTGTAA

Upstream 100 bases:

>100_bases
GCTCGTATCCGCGCGCCCGCTGATGATATTCAAGCGGCGGCACGCTGTACCGGGCGCGCCAGCCGCACATCCCATTACTC
ATAGTCGTTCGGAGATTCTC

Downstream 100 bases:

>100_bases
GCGGTAACCCTTGACCCGCGCGCCTCGTCGGCATGACAGGCGCGCTCTATTTGTGACCGACGTGGCCGCGTTTTCTTTTG
ACAAACTGGTAATTTTCGGT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 1 [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTASFGPSYVRAIAPYVAGKPISEVAREFDLDEKTIVKLASNENPLGMPESAQRAMAQAASELGRYPDANAFELKAALSK
RYGVPADWITLGNGSNDILEIAAHAFVEKDQSIVYAQYSFAVYALATQGLGARAIVVPAVGYGHDLGAMLAAITDDTRLI
FVANPNNPTGTFIEGAKLEAFLDKVPRNVVVVLDEAYTEYLPQEKRYDSIAWVRRYPNLLVSRTFSKAFGLAGLRVGFAI
AQPELTDLLNRLRQPFNVNTLAQAAAIAALNDRAFLEKSAVLNAQGYRRLTEAFDKLGLEYVPSDGNFVLVRVGNDDAAG
NRVNLALLKQGVIVRPVGNYGLPQWLRVTIGLPEENEAFVAALEKALATV

Sequences:

>Translated_370_residues
MTASFGPSYVRAIAPYVAGKPISEVAREFDLDEKTIVKLASNENPLGMPESAQRAMAQAASELGRYPDANAFELKAALSK
RYGVPADWITLGNGSNDILEIAAHAFVEKDQSIVYAQYSFAVYALATQGLGARAIVVPAVGYGHDLGAMLAAITDDTRLI
FVANPNNPTGTFIEGAKLEAFLDKVPRNVVVVLDEAYTEYLPQEKRYDSIAWVRRYPNLLVSRTFSKAFGLAGLRVGFAI
AQPELTDLLNRLRQPFNVNTLAQAAAIAALNDRAFLEKSAVLNAQGYRRLTEAFDKLGLEYVPSDGNFVLVRVGNDDAAG
NRVNLALLKQGVIVRPVGNYGLPQWLRVTIGLPEENEAFVAALEKALATV
>Mature_369_residues
TASFGPSYVRAIAPYVAGKPISEVAREFDLDEKTIVKLASNENPLGMPESAQRAMAQAASELGRYPDANAFELKAALSKR
YGVPADWITLGNGSNDILEIAAHAFVEKDQSIVYAQYSFAVYALATQGLGARAIVVPAVGYGHDLGAMLAAITDDTRLIF
VANPNNPTGTFIEGAKLEAFLDKVPRNVVVVLDEAYTEYLPQEKRYDSIAWVRRYPNLLVSRTFSKAFGLAGLRVGFAIA
QPELTDLLNRLRQPFNVNTLAQAAAIAALNDRAFLEKSAVLNAQGYRRLTEAFDKLGLEYVPSDGNFVLVRVGNDDAAGN
RVNLALLKQGVIVRPVGNYGLPQWLRVTIGLPEENEAFVAALEKALATV

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=310, Percent_Identity=30.3225806451613, Blast_Score=126, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6322075, Length=360, Percent_Identity=30, Blast_Score=139, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40108; Mature: 39977

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASFGPSYVRAIAPYVAGKPISEVAREFDLDEKTIVKLASNENPLGMPESAQRAMAQAA
CCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHEEEECCCCCCCCCHHHHHHHHHHH
SELGRYPDANAFELKAALSKRYGVPADWITLGNGSNDILEIAAHAFVEKDQSIVYAQYSF
HHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEEHHH
AVYALATQGLGARAIVVPAVGYGHDLGAMLAAITDDTRLIFVANPNNPTGTFIEGAKLEA
EEEEEHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCEEECCHHHH
FLDKVPRNVVVVLDEAYTEYLPQEKRYDSIAWVRRYPNLLVSRTFSKAFGLAGLRVGFAI
HHHHCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEE
AQPELTDLLNRLRQPFNVNTLAQAAAIAALNDRAFLEKSAVLNAQGYRRLTEAFDKLGLE
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHCCCE
YVPSDGNFVLVRVGNDDAAGNRVNLALLKQGVIVRPVGNYGLPQWLRVTIGLPEENEAFV
EECCCCCEEEEEECCCCCCCCEEEEEEECCCEEEEECCCCCCCCEEEEEECCCCCCHHHH
AALEKALATV
HHHHHHHHCC
>Mature Secondary Structure 
TASFGPSYVRAIAPYVAGKPISEVAREFDLDEKTIVKLASNENPLGMPESAQRAMAQAA
CCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHEEEECCCCCCCCCHHHHHHHHHHH
SELGRYPDANAFELKAALSKRYGVPADWITLGNGSNDILEIAAHAFVEKDQSIVYAQYSF
HHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEEHHH
AVYALATQGLGARAIVVPAVGYGHDLGAMLAAITDDTRLIFVANPNNPTGTFIEGAKLEA
EEEEEHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCEEECCHHHH
FLDKVPRNVVVVLDEAYTEYLPQEKRYDSIAWVRRYPNLLVSRTFSKAFGLAGLRVGFAI
HHHHCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEE
AQPELTDLLNRLRQPFNVNTLAQAAAIAALNDRAFLEKSAVLNAQGYRRLTEAFDKLGLE
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHCCCE
YVPSDGNFVLVRVGNDDAAGNRVNLALLKQGVIVRPVGNYGLPQWLRVTIGLPEENEAFV
EECCCCCEEEEEECCCCCCCCEEEEEEECCCEEEEECCCCCCCCEEEEEECCCCCCHHHH
AALEKALATV
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA