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The map label for this gene is pncB [H]

Identifier: 91784741

GI number: 91784741

Start: 3728506

End: 3729744

Strand: Reverse

Name: pncB [H]

Synonym: Bxe_A1052

Alternate gene names: 91784741

Gene position: 3729744-3728506 (Counterclockwise)

Preceding gene: 91784748

Following gene: 91784740

Centisome position: 76.18

GC content: 59.56

Gene sequence:

>1239_bases
GTGTCGGGCCTTCCGTTTTCCTGCAGTTCAGTTCGCACCATCATGATTATTACTTCGCTGCTCGACACCGATCTGTACAA
GTTCACGATGATGCAAGTGGTCTTGCATCACTTTCCCGCAGCGAACGTCGAATATCGCTTCCGTTGCCGCACGCCGAACG
TCGATCTCGTGCCGTATATCGGCGAGATTCGCGACGAAGTGCGCAAGCTCTGCCAACTCCGCTTCACCGACGACGAACTC
GACTACCTGCGCCGCATGCGCTTCATCAAGGGCGACTTCATCGAGTTTCTCGCGCTGTTCCATCTGAACGAAAAATACAT
TTCGATCGGGCCTTCGCCCAAGGGCAATGGCGAAATCGACATCGAGATCAAGGGGCCGTGGCTGCATACGATCCTGTTCG
AGATTCCGATGCTCGCGATCGTCAACGAAGTCTACTTCCGCAACACCCAGCAAAAGCCGGACTATAGCGAAGGGCGCGGC
CGTCTCGTCGAGAAGATCAAGCTCCTCGGCGCGCGTCCGGAATTCGCCGACTGCAAGATCGCCGACTACGGTACGCGCCG
CCGCTTCTCGAAGCAATGGCACGAGGAAGTGATCCTCAAGCTCAAAGAGGGCCTCGGCGAGCAGTTCGCCGGCACCAGCA
ACGTCTTCTACGCAATGAAGCACGGCCTCACGCCGCTCGGCACGATGGCGCACGAATACCTGCAGGCGTGTCAGGCGCTC
GGTCCGCGGCTGCGCGATTCGCAGATTTTCGGCTTCGAGATGTGGGCCAAGGAATACCGCGGCGACCTGGGTATCGCGCT
GTCCGACGTGTACGGCATGGAGGCGTTCCTGCGCGACTTCGACATGTATTTCTGCAAGCTGTTCGACGGCGCGCGCCACG
ATTCCGGCGACCCGTTCGACTGGGGCGAACGTCTGCTCAAGCACTACGAAGCGAATCGCTGCGACCCGCGCACCAAGATC
CTCGTATTTTCCGACGCACTCGACATTCCCAAAGTGCTGCAACTCTACGAGCGCTTTCGCGGCCGCTGCAAGCTGGCGTT
CGGCGTGGGCACGAACCTGACCAACGACCTCGGCTATAACCCGCTGCAGATCGTCATCAAGATGGTTCGCTGCAACGGCC
AGCCGGTGGCGAAGCTGTCGGACTCGCCGGGCAAGAACATGTGCGAAGACAAGGCTTACCTCGCTTACCTGCGCCAGGTG
TTCGGCATTGCGCAGCCCGAGGAAGAGGCGGCGAAGTAA

Upstream 100 bases:

>100_bases
CGAGTCCGGCGGCGCGCTGAATCCGGACGCATTCGGGTAACATGCGTGAGGTCGGTGCGCACGGGGCGTGCCGTATGCGC
ATGGGTGAGTCGGACCTTTC

Downstream 100 bases:

>100_bases
CGCGGCTCGCAGCCGGCTATGGCAACTGGCTATAGCGTAAGCCGCGTGGGCGATGCGCGGCAATCGGCCATTCGGCCAGG
GTGGTCGCGCACAAGGCGGC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSGLPFSCSSVRTIMIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPNVDLVPYIGEIRDEVRKLCQLRFTDDEL
DYLRRMRFIKGDFIEFLALFHLNEKYISIGPSPKGNGEIDIEIKGPWLHTILFEIPMLAIVNEVYFRNTQQKPDYSEGRG
RLVEKIKLLGARPEFADCKIADYGTRRRFSKQWHEEVILKLKEGLGEQFAGTSNVFYAMKHGLTPLGTMAHEYLQACQAL
GPRLRDSQIFGFEMWAKEYRGDLGIALSDVYGMEAFLRDFDMYFCKLFDGARHDSGDPFDWGERLLKHYEANRCDPRTKI
LVFSDALDIPKVLQLYERFRGRCKLAFGVGTNLTNDLGYNPLQIVIKMVRCNGQPVAKLSDSPGKNMCEDKAYLAYLRQV
FGIAQPEEEAAK

Sequences:

>Translated_412_residues
MSGLPFSCSSVRTIMIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPNVDLVPYIGEIRDEVRKLCQLRFTDDEL
DYLRRMRFIKGDFIEFLALFHLNEKYISIGPSPKGNGEIDIEIKGPWLHTILFEIPMLAIVNEVYFRNTQQKPDYSEGRG
RLVEKIKLLGARPEFADCKIADYGTRRRFSKQWHEEVILKLKEGLGEQFAGTSNVFYAMKHGLTPLGTMAHEYLQACQAL
GPRLRDSQIFGFEMWAKEYRGDLGIALSDVYGMEAFLRDFDMYFCKLFDGARHDSGDPFDWGERLLKHYEANRCDPRTKI
LVFSDALDIPKVLQLYERFRGRCKLAFGVGTNLTNDLGYNPLQIVIKMVRCNGQPVAKLSDSPGKNMCEDKAYLAYLRQV
FGIAQPEEEAAK
>Mature_411_residues
SGLPFSCSSVRTIMIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPNVDLVPYIGEIRDEVRKLCQLRFTDDELD
YLRRMRFIKGDFIEFLALFHLNEKYISIGPSPKGNGEIDIEIKGPWLHTILFEIPMLAIVNEVYFRNTQQKPDYSEGRGR
LVEKIKLLGARPEFADCKIADYGTRRRFSKQWHEEVILKLKEGLGEQFAGTSNVFYAMKHGLTPLGTMAHEYLQACQALG
PRLRDSQIFGFEMWAKEYRGDLGIALSDVYGMEAFLRDFDMYFCKLFDGARHDSGDPFDWGERLLKHYEANRCDPRTKIL
VFSDALDIPKVLQLYERFRGRCKLAFGVGTNLTNDLGYNPLQIVIKMVRCNGQPVAKLSDSPGKNMCEDKAYLAYLRQVF
GIAQPEEEAAK

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=392, Percent_Identity=42.8571428571429, Blast_Score=331, Evalue=6e-92,
Organism=Saccharomyces cerevisiae, GI6324783, Length=417, Percent_Identity=29.2565947242206, Blast_Score=190, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 47479; Mature: 47348

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLPFSCSSVRTIMIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPNVDLVPYI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCH
GEIRDEVRKLCQLRFTDDELDYLRRMRFIKGDFIEFLALFHLNEKYISIGPSPKGNGEID
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEE
IEIKGPWLHTILFEIPMLAIVNEVYFRNTQQKPDYSEGRGRLVEKIKLLGARPEFADCKI
EEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEE
ADYGTRRRFSKQWHEEVILKLKEGLGEQFAGTSNVFYAMKHGLTPLGTMAHEYLQACQAL
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
GPRLRDSQIFGFEMWAKEYRGDLGIALSDVYGMEAFLRDFDMYFCKLFDGARHDSGDPFD
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
WGERLLKHYEANRCDPRTKILVFSDALDIPKVLQLYERFRGRCKLAFGVGTNLTNDLGYN
HHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
PLQIVIKMVRCNGQPVAKLSDSPGKNMCEDKAYLAYLRQVFGIAQPEEEAAK
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCC
>Mature Secondary Structure 
SGLPFSCSSVRTIMIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPNVDLVPYI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCH
GEIRDEVRKLCQLRFTDDELDYLRRMRFIKGDFIEFLALFHLNEKYISIGPSPKGNGEID
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEE
IEIKGPWLHTILFEIPMLAIVNEVYFRNTQQKPDYSEGRGRLVEKIKLLGARPEFADCKI
EEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEE
ADYGTRRRFSKQWHEEVILKLKEGLGEQFAGTSNVFYAMKHGLTPLGTMAHEYLQACQAL
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
GPRLRDSQIFGFEMWAKEYRGDLGIALSDVYGMEAFLRDFDMYFCKLFDGARHDSGDPFD
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
WGERLLKHYEANRCDPRTKILVFSDALDIPKVLQLYERFRGRCKLAFGVGTNLTNDLGYN
HHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
PLQIVIKMVRCNGQPVAKLSDSPGKNMCEDKAYLAYLRQVFGIAQPEEEAAK
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA