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The map label for this gene is fabF [H]

Identifier: 91784716

GI number: 91784716

Start: 3703615

End: 3704901

Strand: Reverse

Name: fabF [H]

Synonym: Bxe_A1076

Alternate gene names: 91784716

Gene position: 3704901-3703615 (Counterclockwise)

Preceding gene: 91784717

Following gene: 91784715

Centisome position: 75.67

GC content: 61.69

Gene sequence:

>1287_bases
GTGGCCGCTGTGGCTTTTGCTTTTGTCATCTATGAAAAAGGGGTTACCGTGAGCCGCCGTCGTGTTGTTGTTACAGGCCT
GGGGCTGATTTCGCCTGTTGGCAATAATGTTGCCGACGGCTGGGCCAATCTGGTCGCCGGCAAGTCGGGTATTGCCAATA
TCACGAAGTTCGATGCGTCGAACTTTTCGACTCGTTTTGCCGGCGAGGTGAAGGGCTTCAATATCGAGGACTACATCCCC
GGTAAGGAAGCGCGCCACATGGATACGTTTATCCACTACGGCGTGGCTGCAGGCATCCAGGCGATGCAGGACAGCGGCCT
CGAAGTCACCGACGAGAATTCGGAGCGTATCGGCGTGGTGGTTGGTTCGGGCATCGGCGGCTTGCCGATGATCGAAGTGA
CGCAAACCGAACTGCTCAATCGCGGCCCGCGCCGTATTTCGCCGTTCTTCGTGCCGGCGTCGATCATCAACATGATCTCC
GGCCATCTGTCGATCAAGTTCGGCATCAAGGGTCCGAATCTGGCTATCGTCACGGCCTGTACCACGGGCCTGCACTGTAT
CGGCGAGGCGTCGCGCCTGATCGAATACGGCGACGCGGACGTGATGATCGCGGGTGGTGCAGAATCGACCGTATCGCCGC
TCGGCGTCGGCGGCTTTGCGGCGGCGCGCGCGCTGTCGCAACGCAATGACGATCCGGCCACGGCGAGCCGTCCGTGGGAC
AAGGATCGCGACGGTTTCGTGCTGGGCGAGGGCGCCGGCGTCATGGTGCTCGAAGAGTACGAGCACGCGAAGGCACGCGG
CGCGAAGATTTACGCCGAAGTCAGCGGCTATGGGATGAGCGGCGACGCCTATCACATGACCGCCCCGCTGGAAGACGGCG
ACGGCGCGCGCCGCTGCATGCTGGCGGCGTTGAAGAACGCAGGCATCAACCTCGATCAGGTGAATTATCTGAACGCGCAT
GGCACGTCCACGCCGCTCGGCGACCTGGCGGAAACCACCGGCATCAAGCGCGCCTTTGGCGATCATGCCAAAGACATGGT
CGTGAACTCGACCAAGTCGATGACCGGGCACCTGCTGGGCGGCGCCGGCGGTCTGGAGTCGGTGTTTACCGTGCTGGCCG
TGCATCATCAGGTGTCGCCGCCGACGATCAACATCTTCAACCAGGATCCGGCCTGTGATCTGGATTACTGCGCCAATACC
GCGCGGGAGATGAAGATCGACGTCGCGCTGAAGAACTCGTTCGGGTTCGGCGGCACGAACGGCACGCTGGTCTTCAAACG
CGCCTGA

Upstream 100 bases:

>100_bases
AGGAAGTCCTTTTGGGGGATTTCACCCGTCGGGGTGGCTTGGTGCGAAGCACCGGGCGTGGGGGCGCTTAACAGCCACAG
GGCACACAGGGCACATTCCT

Downstream 100 bases:

>100_bases
TCGCCTGATAGTTGGTGACGCGCCAGTCGAAGGCGCCGGGTCGGCCGGCGCGCTCCCCTGAATCGGCAACGCCCGACGGA
GCGCCGCAGCGCATTGCGCT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MAAVAFAFVIYEKGVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIANITKFDASNFSTRFAGEVKGFNIEDYIP
GKEARHMDTFIHYGVAAGIQAMQDSGLEVTDENSERIGVVVGSGIGGLPMIEVTQTELLNRGPRRISPFFVPASIINMIS
GHLSIKFGIKGPNLAIVTACTTGLHCIGEASRLIEYGDADVMIAGGAESTVSPLGVGGFAAARALSQRNDDPATASRPWD
KDRDGFVLGEGAGVMVLEEYEHAKARGAKIYAEVSGYGMSGDAYHMTAPLEDGDGARRCMLAALKNAGINLDQVNYLNAH
GTSTPLGDLAETTGIKRAFGDHAKDMVVNSTKSMTGHLLGGAGGLESVFTVLAVHHQVSPPTINIFNQDPACDLDYCANT
AREMKIDVALKNSFGFGGTNGTLVFKRA

Sequences:

>Translated_428_residues
MAAVAFAFVIYEKGVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIANITKFDASNFSTRFAGEVKGFNIEDYIP
GKEARHMDTFIHYGVAAGIQAMQDSGLEVTDENSERIGVVVGSGIGGLPMIEVTQTELLNRGPRRISPFFVPASIINMIS
GHLSIKFGIKGPNLAIVTACTTGLHCIGEASRLIEYGDADVMIAGGAESTVSPLGVGGFAAARALSQRNDDPATASRPWD
KDRDGFVLGEGAGVMVLEEYEHAKARGAKIYAEVSGYGMSGDAYHMTAPLEDGDGARRCMLAALKNAGINLDQVNYLNAH
GTSTPLGDLAETTGIKRAFGDHAKDMVVNSTKSMTGHLLGGAGGLESVFTVLAVHHQVSPPTINIFNQDPACDLDYCANT
AREMKIDVALKNSFGFGGTNGTLVFKRA
>Mature_427_residues
AAVAFAFVIYEKGVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIANITKFDASNFSTRFAGEVKGFNIEDYIPG
KEARHMDTFIHYGVAAGIQAMQDSGLEVTDENSERIGVVVGSGIGGLPMIEVTQTELLNRGPRRISPFFVPASIINMISG
HLSIKFGIKGPNLAIVTACTTGLHCIGEASRLIEYGDADVMIAGGAESTVSPLGVGGFAAARALSQRNDDPATASRPWDK
DRDGFVLGEGAGVMVLEEYEHAKARGAKIYAEVSGYGMSGDAYHMTAPLEDGDGARRCMLAALKNAGINLDQVNYLNAHG
TSTPLGDLAETTGIKRAFGDHAKDMVVNSTKSMTGHLLGGAGGLESVFTVLAVHHQVSPPTINIFNQDPACDLDYCANTA
REMKIDVALKNSFGFGGTNGTLVFKRA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=424, Percent_Identity=46.9339622641509, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI223972627, Length=147, Percent_Identity=53.7414965986395, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI41872631, Length=425, Percent_Identity=24.7058823529412, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI1787337, Length=412, Percent_Identity=62.1359223300971, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1788663, Length=414, Percent_Identity=40.0966183574879, Blast_Score=265, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI71983541, Length=414, Percent_Identity=36.231884057971, Blast_Score=250, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71983535, Length=255, Percent_Identity=40.7843137254902, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI212642053, Length=419, Percent_Identity=24.8210023866348, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=418, Percent_Identity=24.1626794258373, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320904, Length=446, Percent_Identity=35.8744394618834, Blast_Score=268, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24644341, Length=418, Percent_Identity=44.7368421052632, Blast_Score=348, Evalue=3e-96,
Organism=Drosophila melanogaster, GI19920632, Length=389, Percent_Identity=25.1928020565553, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI221330659, Length=389, Percent_Identity=25.1928020565553, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24581345, Length=428, Percent_Identity=22.8971962616822, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 45003; Mature: 44871

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVAFAFVIYEKGVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIANITKFDAS
CCHHHEEEEEEECCCCEECCEEEEEECCHHCCCCCCHHHHHHHHHCCCCCCCCEEEECCC
NFSTRFAGEVKGFNIEDYIPGKEARHMDTFIHYGVAAGIQAMQDSGLEVTDENSERIGVV
CCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEE
VGSGIGGLPMIEVTQTELLNRGPRRISPFFVPASIINMISGHLSIKFGIKGPNLAIVTAC
EECCCCCCCEEEEHHHHHHCCCCCCCCCEEEHHHHHHHHCCCEEEEEECCCCCEEEEEEE
TTGLHCIGEASRLIEYGDADVMIAGGAESTVSPLGVGGFAAARALSQRNDDPATASRPWD
CCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
KDRDGFVLGEGAGVMVLEEYEHAKARGAKIYAEVSGYGMSGDAYHMTAPLEDGDGARRCM
CCCCCEEEECCCCEEEEECCHHHHCCCCEEEEEEECCCCCCCCEEEECCCCCCCHHHHHH
LAALKNAGINLDQVNYLNAHGTSTPLGDLAETTGIKRAFGDHAKDMVVNSTKSMTGHLLG
HHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHEECCCHHHCEEEEC
GAGGLESVFTVLAVHHQVSPPTINIFNQDPACDLDYCANTAREMKIDVALKNSFGFGGTN
CCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCHHEEEEEEEECCCCCCCCC
GTLVFKRA
CEEEEEEC
>Mature Secondary Structure 
AAVAFAFVIYEKGVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIANITKFDAS
CHHHEEEEEEECCCCEECCEEEEEECCHHCCCCCCHHHHHHHHHCCCCCCCCEEEECCC
NFSTRFAGEVKGFNIEDYIPGKEARHMDTFIHYGVAAGIQAMQDSGLEVTDENSERIGVV
CCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEE
VGSGIGGLPMIEVTQTELLNRGPRRISPFFVPASIINMISGHLSIKFGIKGPNLAIVTAC
EECCCCCCCEEEEHHHHHHCCCCCCCCCEEEHHHHHHHHCCCEEEEEECCCCCEEEEEEE
TTGLHCIGEASRLIEYGDADVMIAGGAESTVSPLGVGGFAAARALSQRNDDPATASRPWD
CCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
KDRDGFVLGEGAGVMVLEEYEHAKARGAKIYAEVSGYGMSGDAYHMTAPLEDGDGARRCM
CCCCCEEEECCCCEEEEECCHHHHCCCCEEEEEEECCCCCCCCEEEECCCCCCCHHHHHH
LAALKNAGINLDQVNYLNAHGTSTPLGDLAETTGIKRAFGDHAKDMVVNSTKSMTGHLLG
HHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHEECCCHHHCEEEEC
GAGGLESVFTVLAVHHQVSPPTINIFNQDPACDLDYCANTAREMKIDVALKNSFGFGGTN
CCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCHHEEEEEEEECCCCCCCCC
GTLVFKRA
CEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]