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The map label for this gene is intA [H]

Identifier: 91784522

GI number: 91784522

Start: 3507259

End: 3508623

Strand: Reverse

Name: intA [H]

Synonym: Bxe_A1277

Alternate gene names: 91784522

Gene position: 3508623-3507259 (Counterclockwise)

Preceding gene: 91784525

Following gene: 91784521

Centisome position: 71.67

GC content: 61.25

Gene sequence:

>1365_bases
ATGGCAAGCAAGCTCACTGTAAAAGAACTGGAAGCTCTAAAACCCGCCGATATCGGCACGACGATCCGGGACGAGGGTGG
TATATGGGGAAGGGTCCGCAAGGCCGGTGACGGCGTTTCTGTGACCTTTTGGTATCGGTATAAGTGGCAGGCCAAGACCC
GCGATACCGCGATTGGCACATGGCCCGCCGCGAGCCTGCCGAAGATCAGGAAGAACCGGGACGCCGCGCGCGCACTCGTC
AAGGATGGACGCGACCCCAACGAGCAGCGTGAAATTGACCGGCGCGACCGGGAAGCCGCCGAAGCGCTGCGCAAGGCCGA
GGCGTTGACCGTGAGCGATCTGTACGATGCATGGTTCCCCACGATCAGCGTGAAGCGTGGCAAACGTGGCCGGAAAGACG
AGGGCAAGGAAATCGAACGCACGTTCAATTTGTTCGTGCTGAAGAAGATCGGCACCAAGCTGTTGACGACCATCTACAAG
TCGGACGTGCAACCGATCCTGACCCGGATATCTGACGGAGGAGCGAACCGGCAGGCTACAGCGTTGCTCACCGACCTGAA
GCAGATGTTTCGCTGGGGCGACCAGAATCAACCATACAAGCGGCTACTCGCCGCCAGTGACGTACTGGCGATCAAGCCGG
AGGACATTGTGAGCGGCGACTACGATCCGGTTGCCGACAACGAGCGAACCCGCGTGCTGACCGAGGCGGAGATCAGGCAG
CTTGCCAAGCTCGTTCCTGCCGCCGACCTGCCGCTCACAACGCGCGCCGCAATCTGGATCATGTTGTCGTGCGGCACCCG
TATCGGTGAGACCGTCGCCACGAAGTGGGCGCATGTCGATCTGCAAACCGGTCGCTGGTCGATCCCGAAGGAACACACCA
AGTCAGGTGTGGCGCTGGAAGTTGCGTTGTCTGACTTCGCACTCGCGCAATTCCAGACACTTGCGGATGCACGTGACGCC
CTGCCGGTTGAGGATCGCAGCGACTACGTGTTTCCGAGCCGTAACGACCGAACCAAGCCGCTCAACAATCAGGCAGTGGG
CAAGCAGCTTGCCGATCGCCAGCGGACCAGTGGGGAACCGATCAAGGGCAGGACGGAGAAGGTGGACGCGCTCGCGCTCG
ACGGCGGGCAATGGCGTTGCCATGACCTTCGCCGCACGGCGGGGACGCTTATGCAGTCGCTTGGCGTACCGGAGTCCATC
GTCCACCGTTGCCTGAATCACGCACGCAGTGACAAGCTCGATCGCGTGTACCTGCAACACGACTACTCGAAGGAGATGGC
CGAGGCGTGGGCGGCACTCGGTGTGCGCTTACAGGCATTGAAGACCGACAATGTGCTGACCCTGCCGAATGCATCCGTCG
CCTGA

Upstream 100 bases:

>100_bases
TGACAGGAAAGCGATTCAAGGAAGTGTGCATCCTGTTACATAGATTTTTTATCCGGTATCATCCGGGAGTTCGGTTGGGG
TCAAAGTTGGGGTCAAGGAA

Downstream 100 bases:

>100_bases
CGGTTCTACCCGTTTGCATCCGATTTGTGAGCGGCGTATCCTCGTCACTGTGGTTTCAGTCGGAGCCACGAAGATTTGAT
TGCCCGATACGTAGTGCCAT

Product: putative phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MASKLTVKELEALKPADIGTTIRDEGGIWGRVRKAGDGVSVTFWYRYKWQAKTRDTAIGTWPAASLPKIRKNRDAARALV
KDGRDPNEQREIDRRDREAAEALRKAEALTVSDLYDAWFPTISVKRGKRGRKDEGKEIERTFNLFVLKKIGTKLLTTIYK
SDVQPILTRISDGGANRQATALLTDLKQMFRWGDQNQPYKRLLAASDVLAIKPEDIVSGDYDPVADNERTRVLTEAEIRQ
LAKLVPAADLPLTTRAAIWIMLSCGTRIGETVATKWAHVDLQTGRWSIPKEHTKSGVALEVALSDFALAQFQTLADARDA
LPVEDRSDYVFPSRNDRTKPLNNQAVGKQLADRQRTSGEPIKGRTEKVDALALDGGQWRCHDLRRTAGTLMQSLGVPESI
VHRCLNHARSDKLDRVYLQHDYSKEMAEAWAALGVRLQALKTDNVLTLPNASVA

Sequences:

>Translated_454_residues
MASKLTVKELEALKPADIGTTIRDEGGIWGRVRKAGDGVSVTFWYRYKWQAKTRDTAIGTWPAASLPKIRKNRDAARALV
KDGRDPNEQREIDRRDREAAEALRKAEALTVSDLYDAWFPTISVKRGKRGRKDEGKEIERTFNLFVLKKIGTKLLTTIYK
SDVQPILTRISDGGANRQATALLTDLKQMFRWGDQNQPYKRLLAASDVLAIKPEDIVSGDYDPVADNERTRVLTEAEIRQ
LAKLVPAADLPLTTRAAIWIMLSCGTRIGETVATKWAHVDLQTGRWSIPKEHTKSGVALEVALSDFALAQFQTLADARDA
LPVEDRSDYVFPSRNDRTKPLNNQAVGKQLADRQRTSGEPIKGRTEKVDALALDGGQWRCHDLRRTAGTLMQSLGVPESI
VHRCLNHARSDKLDRVYLQHDYSKEMAEAWAALGVRLQALKTDNVLTLPNASVA
>Mature_453_residues
ASKLTVKELEALKPADIGTTIRDEGGIWGRVRKAGDGVSVTFWYRYKWQAKTRDTAIGTWPAASLPKIRKNRDAARALVK
DGRDPNEQREIDRRDREAAEALRKAEALTVSDLYDAWFPTISVKRGKRGRKDEGKEIERTFNLFVLKKIGTKLLTTIYKS
DVQPILTRISDGGANRQATALLTDLKQMFRWGDQNQPYKRLLAASDVLAIKPEDIVSGDYDPVADNERTRVLTEAEIRQL
AKLVPAADLPLTTRAAIWIMLSCGTRIGETVATKWAHVDLQTGRWSIPKEHTKSGVALEVALSDFALAQFQTLADARDAL
PVEDRSDYVFPSRNDRTKPLNNQAVGKQLADRQRTSGEPIKGRTEKVDALALDGGQWRCHDLRRTAGTLMQSLGVPESIV
HRCLNHARSDKLDRVYLQHDYSKEMAEAWAALGVRLQALKTDNVLTLPNASVA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=436, Percent_Identity=23.394495412844, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 50759; Mature: 50628

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKLTVKELEALKPADIGTTIRDEGGIWGRVRKAGDGVSVTFWYRYKWQAKTRDTAIGT
CCCCCCHHHHHHCCCCCCCCCCCCCCCCEEHHHCCCCCCEEEEEEEEEEECCCCCCCCCC
WPAASLPKIRKNRDAARALVKDGRDPNEQREIDRRDREAAEALRKAEALTVSDLYDAWFP
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TISVKRGKRGRKDEGKEIERTFNLFVLKKIGTKLLTTIYKSDVQPILTRISDGGANRQAT
CEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ALLTDLKQMFRWGDQNQPYKRLLAASDVLAIKPEDIVSGDYDPVADNERTRVLTEAEIRQ
HHHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCHHHCCCCCCCCCCCCHHEEECHHHHHH
LAKLVPAADLPLTTRAAIWIMLSCGTRIGETVATKWAHVDLQTGRWSIPKEHTKSGVALE
HHHHCCCCCCCCCHHHHHHEEECCCCHHHHHHHHHHEEEEECCCCCCCCHHHCCCCEEEE
VALSDFALAQFQTLADARDALPVEDRSDYVFPSRNDRTKPLNNQAVGKQLADRQRTSGEP
EEHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
IKGRTEKVDALALDGGQWRCHDLRRTAGTLMQSLGVPESIVHRCLNHARSDKLDRVYLQH
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHEEHHHC
DYSKEMAEAWAALGVRLQALKTDNVLTLPNASVA
CHHHHHHHHHHHHHHEEEEECCCCEEECCCCCCC
>Mature Secondary Structure 
ASKLTVKELEALKPADIGTTIRDEGGIWGRVRKAGDGVSVTFWYRYKWQAKTRDTAIGT
CCCCCHHHHHHCCCCCCCCCCCCCCCCEEHHHCCCCCCEEEEEEEEEEECCCCCCCCCC
WPAASLPKIRKNRDAARALVKDGRDPNEQREIDRRDREAAEALRKAEALTVSDLYDAWFP
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TISVKRGKRGRKDEGKEIERTFNLFVLKKIGTKLLTTIYKSDVQPILTRISDGGANRQAT
CEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ALLTDLKQMFRWGDQNQPYKRLLAASDVLAIKPEDIVSGDYDPVADNERTRVLTEAEIRQ
HHHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCHHHCCCCCCCCCCCCHHEEECHHHHHH
LAKLVPAADLPLTTRAAIWIMLSCGTRIGETVATKWAHVDLQTGRWSIPKEHTKSGVALE
HHHHCCCCCCCCCHHHHHHEEECCCCHHHHHHHHHHEEEEECCCCCCCCHHHCCCCEEEE
VALSDFALAQFQTLADARDALPVEDRSDYVFPSRNDRTKPLNNQAVGKQLADRQRTSGEP
EEHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
IKGRTEKVDALALDGGQWRCHDLRRTAGTLMQSLGVPESIVHRCLNHARSDKLDRVYLQH
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHEEHHHC
DYSKEMAEAWAALGVRLQALKTDNVLTLPNASVA
CHHHHHHHHHHHHHHEEEEECCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]