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The map label for this gene is uppP2

Identifier: 91784500

GI number: 91784500

Start: 3492604

End: 3493434

Strand: Reverse

Name: uppP2

Synonym: Bxe_A1299

Alternate gene names: 91784500

Gene position: 3493434-3492604 (Counterclockwise)

Preceding gene: 91784501

Following gene: 91784497

Centisome position: 71.36

GC content: 62.94

Gene sequence:

>831_bases
GTGAACCTGTCGTTTCTCATTTTCCTGAGCGTGCTGCAAGGCGTCACCGAACTGTTTCCGGTGAGCAGCCTCGGCCATAC
GCTGCTCGTGCCCGCATTGTTCGGTATGCATATCGACAAACACGCGCCGCAATTGCTGCCGTTCCTCGTCGCACTGCATC
TCGGCACGGCGTTCGCGCTGCTGTGGTACTTCCGCAAGCGCTGGTGCGCGCTGGTGCGCGGTTTCTTCGCGTCGTTCGGT
GGCCGCCGTAACGACGACGCGCACATGATGTGGGCGCTGATCATCGGCACGATTCCGGCGGGTCTCGTCGGACTGCTGCT
GGAAAAGCGGCTCGAAAGGATTTTTCACGATTTGCGGATCGTCGCGATTGCGCTGATCGTCAACGGTGTGCTGCTGTGGT
TCGGCGACCGTCTGCAACGCACGCGTGCGCATCAGGCGCCGGAGAAGCTGACTTTCCGGCAGGCGTTTTTCGTTGGTCTC
GCGCAGATCGGCGCGTTGATCCCGGGCTTCTCGCGTAGCGGTCTGACGATGATCGCCGGCAATGCGGCCGGCCTGACGGC
GGAGAAGGCGGCGGAGTTCTCGTTCCTGCTCGGCACGCCAATCATCTTCGCGGCGGGCGTGCTCGAACTGCCCAAGCTGT
TCCATGCGCCGGGCCAACTCGCGGACGCGCTGCTCGGTGGTGTGCTGACCGCGATCGCCGCGTATCTCAGCGTGCGTTTC
CTGATGCGCTATTTCGAAGGCCGCGGACGTCTGGCTTCGTTCGGCGTGTACTGCGTGATTGCCGGGATTGTGTTCCTGGG
CTGGTTCCTGCTGCATCCGCAACCGGTCTGA

Upstream 100 bases:

>100_bases
TGGCATTGCAGCCAGGCATAATCGGTGCGCTTTTGACGCGTCCGCAGATTCCTTGTCTGGCGCGCTATTCCCCGACATTA
TCCTTACAAGGACCTGCCGC

Downstream 100 bases:

>100_bases
TCGGGTTCGCCATGTCCGTTGCGTGCTGGCGGGCAGGGAGCGATCGGTTATAATCCGGGCCCGGCTCAAGCTGCCGGGCC
CGTTTGTTTTATGACTGTGA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 2; Undecaprenyl pyrophosphate phosphatase 2

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MNLSFLIFLSVLQGVTELFPVSSLGHTLLVPALFGMHIDKHAPQLLPFLVALHLGTAFALLWYFRKRWCALVRGFFASFG
GRRNDDAHMMWALIIGTIPAGLVGLLLEKRLERIFHDLRIVAIALIVNGVLLWFGDRLQRTRAHQAPEKLTFRQAFFVGL
AQIGALIPGFSRSGLTMIAGNAAGLTAEKAAEFSFLLGTPIIFAAGVLELPKLFHAPGQLADALLGGVLTAIAAYLSVRF
LMRYFEGRGRLASFGVYCVIAGIVFLGWFLLHPQPV

Sequences:

>Translated_276_residues
MNLSFLIFLSVLQGVTELFPVSSLGHTLLVPALFGMHIDKHAPQLLPFLVALHLGTAFALLWYFRKRWCALVRGFFASFG
GRRNDDAHMMWALIIGTIPAGLVGLLLEKRLERIFHDLRIVAIALIVNGVLLWFGDRLQRTRAHQAPEKLTFRQAFFVGL
AQIGALIPGFSRSGLTMIAGNAAGLTAEKAAEFSFLLGTPIIFAAGVLELPKLFHAPGQLADALLGGVLTAIAAYLSVRF
LMRYFEGRGRLASFGVYCVIAGIVFLGWFLLHPQPV
>Mature_276_residues
MNLSFLIFLSVLQGVTELFPVSSLGHTLLVPALFGMHIDKHAPQLLPFLVALHLGTAFALLWYFRKRWCALVRGFFASFG
GRRNDDAHMMWALIIGTIPAGLVGLLLEKRLERIFHDLRIVAIALIVNGVLLWFGDRLQRTRAHQAPEKLTFRQAFFVGL
AQIGALIPGFSRSGLTMIAGNAAGLTAEKAAEFSFLLGTPIIFAAGVLELPKLFHAPGQLADALLGGVLTAIAAYLSVRF
LMRYFEGRGRLASFGVYCVIAGIVFLGWFLLHPQPV

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=268, Percent_Identity=30.5970149253731, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP2_BURXL (Q13W85)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_559706.1
- GeneID:   4005068
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A1299
- HOGENOM:   HBG391969
- OMA:   FALLWYF
- ProtClustDB:   PRK12554
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30269; Mature: 30269

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x18af3e74)-; HASH(0x1a68aa34)-; HASH(0x1a68cf80)-; HASH(0x15a9bdd8)-; HASH(0x1a694db8)-; HASH(0x19f6d3cc)-; HASH(0x1a925e64)-; HASH(0x196ee614)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure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HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA