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The map label for this gene is pyrG [H]

Identifier: 91784230

GI number: 91784230

Start: 3174036

End: 3175709

Strand: Reverse

Name: pyrG [H]

Synonym: Bxe_A1571

Alternate gene names: 91784230

Gene position: 3175709-3174036 (Counterclockwise)

Preceding gene: 91784231

Following gene: 91784229

Centisome position: 64.87

GC content: 61.59

Gene sequence:

>1674_bases
ATGACCAAATATGTTTTCGTCACCGGCGGCGTAGTATCTTCCCTCGGCAAGGGTATTGCCGCCGCTTCCCTCGCCGCGAT
CCTCGAATCGCGCGGTCTTAAAGTCACCCTCCTCAAGCTCGATCCCTACATCAATGTCGACCCCGGCACGATGAGCCCGT
TTCAACACGGCGAAGTGTTCGTGACGGAAGACGGAGCGGAGACCGACCTCGACCTCGGCCACTATGAGCGCTTCATCAGC
ACGAAGATGCGCAAGGCCAATAACTTCACCACGGGCCAGATTTACGAATCGGTGATCCGCAAGGAACGCCGCGGCGATTA
TCTCGGCAAGACGGTGCAGGTCATTCCGCACATCACGAACGAAATCCAGGCGTTCATCGAACGCGGCGCGGCTTCCGCAA
CGTGCGGTGAGCCGGACGTCGCCATCGTCGAAGTGGGCGGCACCGTGGGCGACATCGAATCGCTGCCGTTCCTCGAAGCC
GCGCGTCAGATGAGCCTGCGCATGGGCCGCAACAGCGCGTGCTTCGTGCACCTCACGCTGGTGCCGTGGGTTGCCACGGC
CGGCGAACTGAAGACCAAGCCCACGCAGCACAGCGTGCAGAAGCTGCGCGAAATCGGTATCTCGCCGCACGTGCTGCTGT
GCCGCGCCGACCGCCGCATTCCGGACGACGAGCGCGCGAAGATCTCCATGTTCTCGAACGTGCCGGAAGACGCGGTGATC
TCGGTGTGGGACGCGGACAGCATCTACAAGATTCCGCAGATGCTGCACGATCAGGGTTTGGACGCGATCATCTGCGAAGA
ACTCAAGCTCGAGCCGAAGGCCGCCGATCTGTCCATGTGGTCCGATCTGGTCGAGAAGCTGGAGCATCCGAGGCATGAAG
TCACGATCGGCATGGTCGGCAAATACGTCGATCTGACCGAGTCGTACAAGTCGCTGATCGAAGCGCTGCGCCATGCGTCG
ATGCATACGTCGACCAAGGTCAACATCGAATACATCGACTCCGAAGAAATCGAGACGCACGGCGTCGAAAGCCTCAAGCA
TCTGGACGCGGTGCTCGTGCCGGGCGGCTTTGGCCGGCGCGGCACCGAAGGCAAGATCGCCGCGATCCGTTATGCCCGTG
AAGCGAAGGTGCCGTATCTCGGCATCTGCCTCGGCATGCAACTGGCGGTGATCGAATTTGCCCGCGACGTGGTGGGTCTG
AAAGACGCGAACAGCACGGAGTTCGATCAGGAAACGCCGAACCGCGTGGTCGCGCTGATCACCGAATGGTACGACCGCGA
AGGCCGCGTCGAGAAGCGCACGGAAGAGTCGGATCTCGGCGGCACGATGCGCCTCGGTTCGCAACGTTGCCCGATCAAGC
CCGGCACGATGGCCGAAGAGATCTATGGCAAGGACGTGAACGAACGCCATCGCCACCGTTATGAAGTCAATAACCGCTTC
GTGCCCCAGCTCGAAGCCGGCGGCCTTATCATCAGCGCCCGTACCCCGAGTGAAGATCTGCCGGAAATGATGGAACTGCC
GCGCAGCATGCACCCGTGGTTCGTCGGCGTGCAGTTCCATCCGGAATTCACGTCCACGCCGCGTGACGGTCATCCGCTGT
TCAAGTCGTTCGTCGAAGCGGCGCTCGCGCACCAGCAGTCGCGCACGGCGGCCGAAGTCGGGGAGAAAGCATGA

Upstream 100 bases:

>100_bases
GGCCGCCGCGGCGCCATGCATCTGCAGACGCAGCTCGGATTTTGCTGGGGTTGAGACCCTGCTTTACGGTATAATCCGTT
TTTCCCGCGAGCATCCAGCG

Downstream 100 bases:

>100_bases
AACTGGGCGATTTCGAAATCGGGCTCGACAGGCCGTTTTTCCTGATCGCGGGCACCTGTGTCGTCGAATCCGAACAGATG
ACGATCGACACAGCTGGCCG

Product: CTP synthetase

Products: NA

Alternate protein names: CTP synthetase; UTP--ammonia ligase [H]

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFIS
TKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEVGGTVGDIESLPFLEA
ARQMSLRMGRNSACFVHLTLVPWVATAGELKTKPTQHSVQKLREIGISPHVLLCRADRRIPDDERAKISMFSNVPEDAVI
SVWDADSIYKIPQMLHDQGLDAIICEELKLEPKAADLSMWSDLVEKLEHPRHEVTIGMVGKYVDLTESYKSLIEALRHAS
MHTSTKVNIEYIDSEEIETHGVESLKHLDAVLVPGGFGRRGTEGKIAAIRYAREAKVPYLGICLGMQLAVIEFARDVVGL
KDANSTEFDQETPNRVVALITEWYDREGRVEKRTEESDLGGTMRLGSQRCPIKPGTMAEEIYGKDVNERHRHRYEVNNRF
VPQLEAGGLIISARTPSEDLPEMMELPRSMHPWFVGVQFHPEFTSTPRDGHPLFKSFVEAALAHQQSRTAAEVGEKA

Sequences:

>Translated_557_residues
MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFIS
TKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEVGGTVGDIESLPFLEA
ARQMSLRMGRNSACFVHLTLVPWVATAGELKTKPTQHSVQKLREIGISPHVLLCRADRRIPDDERAKISMFSNVPEDAVI
SVWDADSIYKIPQMLHDQGLDAIICEELKLEPKAADLSMWSDLVEKLEHPRHEVTIGMVGKYVDLTESYKSLIEALRHAS
MHTSTKVNIEYIDSEEIETHGVESLKHLDAVLVPGGFGRRGTEGKIAAIRYAREAKVPYLGICLGMQLAVIEFARDVVGL
KDANSTEFDQETPNRVVALITEWYDREGRVEKRTEESDLGGTMRLGSQRCPIKPGTMAEEIYGKDVNERHRHRYEVNNRF
VPQLEAGGLIISARTPSEDLPEMMELPRSMHPWFVGVQFHPEFTSTPRDGHPLFKSFVEAALAHQQSRTAAEVGEKA
>Mature_556_residues
TKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFIST
KMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEVGGTVGDIESLPFLEAA
RQMSLRMGRNSACFVHLTLVPWVATAGELKTKPTQHSVQKLREIGISPHVLLCRADRRIPDDERAKISMFSNVPEDAVIS
VWDADSIYKIPQMLHDQGLDAIICEELKLEPKAADLSMWSDLVEKLEHPRHEVTIGMVGKYVDLTESYKSLIEALRHASM
HTSTKVNIEYIDSEEIETHGVESLKHLDAVLVPGGFGRRGTEGKIAAIRYAREAKVPYLGICLGMQLAVIEFARDVVGLK
DANSTEFDQETPNRVVALITEWYDREGRVEKRTEESDLGGTMRLGSQRCPIKPGTMAEEIYGKDVNERHRHRYEVNNRFV
PQLEAGGLIISARTPSEDLPEMMELPRSMHPWFVGVQFHPEFTSTPRDGHPLFKSFVEAALAHQQSRTAAEVGEKA

Specific function: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen [H]

COG id: COG0504

COG function: function code F; CTP synthase (UTP-ammonia lyase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI28559085, Length=559, Percent_Identity=44.9016100178891, Blast_Score=484, Evalue=1e-136,
Organism=Homo sapiens, GI28559083, Length=559, Percent_Identity=44.9016100178891, Blast_Score=484, Evalue=1e-136,
Organism=Homo sapiens, GI221316689, Length=559, Percent_Identity=44.9016100178891, Blast_Score=484, Evalue=1e-136,
Organism=Homo sapiens, GI148491070, Length=562, Percent_Identity=45.5516014234875, Blast_Score=481, Evalue=1e-136,
Organism=Escherichia coli, GI1789142, Length=548, Percent_Identity=62.043795620438, Blast_Score=684, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25148299, Length=609, Percent_Identity=39.9014778325123, Blast_Score=425, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6319432, Length=570, Percent_Identity=42.4561403508772, Blast_Score=454, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6322563, Length=574, Percent_Identity=42.3344947735192, Blast_Score=448, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24664469, Length=560, Percent_Identity=45.8928571428571, Blast_Score=483, Evalue=1e-136,
Organism=Drosophila melanogaster, GI21357815, Length=505, Percent_Identity=44.5544554455446, Blast_Score=409, Evalue=1e-114,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004468
- InterPro:   IPR017456
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF06418 CTP_synth_N; PF00117 GATase [H]

EC number: =6.3.4.2 [H]

Molecular weight: Translated: 61903; Mature: 61772

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVF
CCEEEEEECHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCCCCCCCEEE
VTEDGAETDLDLGHYERFISTKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITN
EECCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHCCHHHHHHHHHH
EIQAFIERGAASATCGEPDVAIVEVGGTVGDIESLPFLEAARQMSLRMGRNSACFVHLTL
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEE
VPWVATAGELKTKPTQHSVQKLREIGISPHVLLCRADRRIPDDERAKISMFSNVPEDAVI
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCEE
SVWDADSIYKIPQMLHDQGLDAIICEELKLEPKAADLSMWSDLVEKLEHPRHEVTIGMVG
EEECCCHHHHHHHHHHHCCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHH
KYVDLTESYKSLIEALRHASMHTSTKVNIEYIDSEEIETHGVESLKHLDAVLVPGGFGRR
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEECCCCCCC
GTEGKIAAIRYAREAKVPYLGICLGMQLAVIEFARDVVGLKDANSTEFDQETPNRVVALI
CCCCCEEEEEEHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
TEWYDREGRVEKRTEESDLGGTMRLGSQRCPIKPGTMAEEIYGKDVNERHRHRYEVNNRF
HHHHCCCCCCHHCCCHHCCCCEEECCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCC
VPQLEAGGLIISARTPSEDLPEMMELPRSMHPWFVGVQFHPEFTSTPRDGHPLFKSFVEA
CCEECCCCEEEECCCCCCCHHHHHHCCHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
ALAHQQSRTAAEVGEKA
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVF
CEEEEEECHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCCCCCCCEEE
VTEDGAETDLDLGHYERFISTKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITN
EECCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHCCHHHHHHHHHH
EIQAFIERGAASATCGEPDVAIVEVGGTVGDIESLPFLEAARQMSLRMGRNSACFVHLTL
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEE
VPWVATAGELKTKPTQHSVQKLREIGISPHVLLCRADRRIPDDERAKISMFSNVPEDAVI
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCEE
SVWDADSIYKIPQMLHDQGLDAIICEELKLEPKAADLSMWSDLVEKLEHPRHEVTIGMVG
EEECCCHHHHHHHHHHHCCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHH
KYVDLTESYKSLIEALRHASMHTSTKVNIEYIDSEEIETHGVESLKHLDAVLVPGGFGRR
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEECCCCCCC
GTEGKIAAIRYAREAKVPYLGICLGMQLAVIEFARDVVGLKDANSTEFDQETPNRVVALI
CCCCCEEEEEEHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
TEWYDREGRVEKRTEESDLGGTMRLGSQRCPIKPGTMAEEIYGKDVNERHRHRYEVNNRF
HHHHCCCCCCHHCCCHHCCCCEEECCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCC
VPQLEAGGLIISARTPSEDLPEMMELPRSMHPWFVGVQFHPEFTSTPRDGHPLFKSFVEA
CCEECCCCEEEECCCCCCCHHHHHHCCHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
ALAHQQSRTAAEVGEKA
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA