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The map label for this gene is gltX [H]

Identifier: 91784159

GI number: 91784159

Start: 3095331

End: 3096740

Strand: Reverse

Name: gltX [H]

Synonym: Bxe_A1642

Alternate gene names: 91784159

Gene position: 3096740-3095331 (Counterclockwise)

Preceding gene: 91784161

Following gene: 91784158

Centisome position: 63.25

GC content: 64.61

Gene sequence:

>1410_bases
ATGACCACCTCTGTTCGCACCCGTTTCGCACCGAGTCCCACCGGCTTCATCCACCTCGGCAACATTCGCTCCGCGCTTTA
TCCGTGGGCGTTCGCGCGCAAGATGAAAGGGACCTTCGTGCTGCGGATCGAGGACACCGACGTCGAGCGCTCCACGAGCG
AATCCGTCGACGCCATTCTCGAAGGCATGGCGTGGCTCGGCCTCGATTTCGACGAAGGTCCGTTCTACCAGATGCAGCGC
ATGGACCGCTACCGCGAAGTGCTCAAGCAGATGCAGGACGAGGGGCTGGTGTACCTGTGCTACATGTCGACGGAAGAACT
GGACGCGTTGCGCGAACGCCAGCGCGAAGCCGGCGAAAAGCCGCGCTACGACGGCACGTGGCGCCCGGAGCCGGGCAAGG
TGCTGCCGGAACCGCCTGCGGGCGTACAGCCGGTGCTGCGCTTCCGCAACCCGCTCAACGGCGTGGTGGCATGGGACGAC
GCCGTAAAGGGCCGCATCGAGATTTCGAACGAGGAACTCGACGACCTCGTGATCGCGCGCCCGGACGGCACGCCGACCTA
CAACTTCTGCGTGGTGGTCGACGATCTGGACATGCGTATCACGCACGTGATTCGCGGCGACGATCACGTCAACAACACGC
CGCGCCAGATCAACATTCTGCGCGCGCTCGGCGGCGAGCCGCCCGTCTATGCGCACCTGCCCACCGTGCTGAACGAACAG
GGCGAGAAGATGAGCAAGCGTCACGGCGCAATGAGCGTGATGGGTTATCGCGACGCCGGTTACCTGCCGGAGGCGGTGGT
CAACTATCTGGCGCGTCTGGGCTGGTCGCATGGCGACGCGGAAATCTTCTCTCGTGAACAGTTCGTCGAGTGGTTCGATC
TGGAGCATCTGGGCAAGTCCCCGGCCCAATATGACCACGACAAGCTGAACTGGCTGAATGCGCACTACATCAAGGAAGCC
GGCAACGTGCGCCTCGCGGAGTTGGCGCGGCCCTTCTTCGCTGGGCTCGGTATCGACGAAGCCATGCTTGCCCAGGGCGC
CGATCTGACCGCCGTGGTGGGCTTGCTGAAGGATCGCGCGTCGACGGTAAAGGAAATCGCAGAGAATGCCGCGATGTTCT
ATCGCGCGCCGGCGCCGGACGCCGAGTCGCTCACGCAGCATGTGACCGACGCGGTGCGGCCGGCGCTCGCCGATCTGGCG
GCCGCGCTCAAGGCAGTGGAGTGGACCAGGGAAGCCATCGCGGCCGCGTTGAAGGCAACGCTCGGCGCGCACAAGCTGAA
GATGCCGCAGCTTGCGATGCCGGTGCGTCTGCTGGTGGCGGGCACCACGCACACGCCGTCGATCGACAGCGTGCTGATGC
TGTTCGGGCGCGATGTGGTGGTGAGCCGTATCGAAAAAGCGCTGGCCTGA

Upstream 100 bases:

>100_bases
TGCCTGCTGCATGGGCGCGGTCCGCTGCCGCGCTTCACGGGCTGCTTCACGGGCTATGTTCCACCCGGGCGCCGGCGCCT
GTCTTTCCGAGTAACCGCTA

Downstream 100 bases:

>100_bases
GCGCGTTCGGGCGCGCCTTGAGCGGGTTTGCATGCGACTTGCGAAAAAAGTCGCATGCAATTGCTCAAAGGGTATTTACA
AAGCGCAAATTGGCCTCTAG

Product: glutamyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamate--tRNA ligase; GluRS [H]

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MTTSVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSTSESVDAILEGMAWLGLDFDEGPFYQMQR
MDRYREVLKQMQDEGLVYLCYMSTEELDALRERQREAGEKPRYDGTWRPEPGKVLPEPPAGVQPVLRFRNPLNGVVAWDD
AVKGRIEISNEELDDLVIARPDGTPTYNFCVVVDDLDMRITHVIRGDDHVNNTPRQINILRALGGEPPVYAHLPTVLNEQ
GEKMSKRHGAMSVMGYRDAGYLPEAVVNYLARLGWSHGDAEIFSREQFVEWFDLEHLGKSPAQYDHDKLNWLNAHYIKEA
GNVRLAELARPFFAGLGIDEAMLAQGADLTAVVGLLKDRASTVKEIAENAAMFYRAPAPDAESLTQHVTDAVRPALADLA
AALKAVEWTREAIAAALKATLGAHKLKMPQLAMPVRLLVAGTTHTPSIDSVLMLFGRDVVVSRIEKALA

Sequences:

>Translated_469_residues
MTTSVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSTSESVDAILEGMAWLGLDFDEGPFYQMQR
MDRYREVLKQMQDEGLVYLCYMSTEELDALRERQREAGEKPRYDGTWRPEPGKVLPEPPAGVQPVLRFRNPLNGVVAWDD
AVKGRIEISNEELDDLVIARPDGTPTYNFCVVVDDLDMRITHVIRGDDHVNNTPRQINILRALGGEPPVYAHLPTVLNEQ
GEKMSKRHGAMSVMGYRDAGYLPEAVVNYLARLGWSHGDAEIFSREQFVEWFDLEHLGKSPAQYDHDKLNWLNAHYIKEA
GNVRLAELARPFFAGLGIDEAMLAQGADLTAVVGLLKDRASTVKEIAENAAMFYRAPAPDAESLTQHVTDAVRPALADLA
AALKAVEWTREAIAAALKATLGAHKLKMPQLAMPVRLLVAGTTHTPSIDSVLMLFGRDVVVSRIEKALA
>Mature_468_residues
TTSVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSTSESVDAILEGMAWLGLDFDEGPFYQMQRM
DRYREVLKQMQDEGLVYLCYMSTEELDALRERQREAGEKPRYDGTWRPEPGKVLPEPPAGVQPVLRFRNPLNGVVAWDDA
VKGRIEISNEELDDLVIARPDGTPTYNFCVVVDDLDMRITHVIRGDDHVNNTPRQINILRALGGEPPVYAHLPTVLNEQG
EKMSKRHGAMSVMGYRDAGYLPEAVVNYLARLGWSHGDAEIFSREQFVEWFDLEHLGKSPAQYDHDKLNWLNAHYIKEAG
NVRLAELARPFFAGLGIDEAMLAQGADLTAVVGLLKDRASTVKEIAENAAMFYRAPAPDAESLTQHVTDAVRPALADLAA
ALKAVEWTREAIAAALKATLGAHKLKMPQLAMPVRLLVAGTTHTPSIDSVLMLFGRDVVVSRIEKALA

Specific function: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction:glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) [H]

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=332, Percent_Identity=34.6385542168675, Blast_Score=195, Evalue=7e-50,
Organism=Escherichia coli, GI1788743, Length=467, Percent_Identity=49.8929336188437, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI226510925, Length=245, Percent_Identity=36.3265306122449, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786895, Length=121, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71993394, Length=482, Percent_Identity=29.045643153527, Blast_Score=184, Evalue=8e-47,
Organism=Saccharomyces cerevisiae, GI6324540, Length=332, Percent_Identity=35.5421686746988, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6321192, Length=233, Percent_Identity=26.6094420600858, Blast_Score=73, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324742, Length=106, Percent_Identity=29.2452830188679, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24665321, Length=500, Percent_Identity=28.4, Blast_Score=217, Evalue=1e-56,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR004527
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: =6.1.1.17 [H]

Molecular weight: Translated: 52305; Mature: 52174

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSTSESVDAIL
CCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHH
EGMAWLGLDFDEGPFYQMQRMDRYREVLKQMQDEGLVYLCYMSTEELDALRERQREAGEK
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHCCCC
PRYDGTWRPEPGKVLPEPPAGVQPVLRFRNPLNGVVAWDDAVKGRIEISNEELDDLVIAR
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCCCEEEEC
PDGTPTYNFCVVVDDLDMRITHVIRGDDHVNNTPRQINILRALGGEPPVYAHLPTVLNEQ
CCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCHHHHHH
GEKMSKRHGAMSVMGYRDAGYLPEAVVNYLARLGWSHGDAEIFSREQFVEWFDLEHLGKS
HHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
PAQYDHDKLNWLNAHYIKEAGNVRLAELARPFFAGLGIDEAMLAQGADLTAVVGLLKDRA
CCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHH
STVKEIAENAAMFYRAPAPDAESLTQHVTDAVRPALADLAAALKAVEWTREAIAAALKAT
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAHKLKMPQLAMPVRLLVAGTTHTPSIDSVLMLFGRDVVVSRIEKALA
HHHHHCCCCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TTSVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSTSESVDAIL
CCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHH
EGMAWLGLDFDEGPFYQMQRMDRYREVLKQMQDEGLVYLCYMSTEELDALRERQREAGEK
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHCCCC
PRYDGTWRPEPGKVLPEPPAGVQPVLRFRNPLNGVVAWDDAVKGRIEISNEELDDLVIAR
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCCCEEEEC
PDGTPTYNFCVVVDDLDMRITHVIRGDDHVNNTPRQINILRALGGEPPVYAHLPTVLNEQ
CCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCHHHHHH
GEKMSKRHGAMSVMGYRDAGYLPEAVVNYLARLGWSHGDAEIFSREQFVEWFDLEHLGKS
HHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
PAQYDHDKLNWLNAHYIKEAGNVRLAELARPFFAGLGIDEAMLAQGADLTAVVGLLKDRA
CCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHH
STVKEIAENAAMFYRAPAPDAESLTQHVTDAVRPALADLAAALKAVEWTREAIAAALKAT
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAHKLKMPQLAMPVRLLVAGTTHTPSIDSVLMLFGRDVVVSRIEKALA
HHHHHCCCCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA