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The map label for this gene is frr [H]

Identifier: 91784116

GI number: 91784116

Start: 3043815

End: 3044375

Strand: Reverse

Name: frr [H]

Synonym: Bxe_A1685

Alternate gene names: 91784116

Gene position: 3044375-3043815 (Counterclockwise)

Preceding gene: 91784117

Following gene: 91784115

Centisome position: 62.18

GC content: 60.43

Gene sequence:

>561_bases
ATGTCTGTGGCTGATATCAGAAAGGGCGCTGAACAAAAGATGCAGCGCTCCATCGACGCGTTCAAGAACGACCTGTCGAA
GATCCGCACGGGCCGTGCGCACACGGGCCTGCTGGATCACATCCAGTGCGACTACTACGGTTCGCCGGTGCCGATTTCGC
AAGTGGCGAACCTGACGCTGATCGACGCCCGCACGATCGGCGTGCAGCCGTGGGAAAAGAAGATGGTTCCGGTTGTCGAA
AAGGCGATCCGCGAGTCGGACCTCGGCCTGAACCCGGCCACGCAAGGCGACGTGATCCGCGTACCGATGCCCGCGCTGAC
CGAAGAACGCCGCCGCGAACTGACCAAAGTGGTCAAGAGCGAAGCGGAAACGGCCAAGGTGGCGGTGCGCAACCTGCGCC
GCGACGCCAACGAGCAACTGAAGAAGCTCGTGAAAGACAAGGAAATTTCGGAAGACGACGAGCGCCGTGCGGGTGACGAC
GTTCAGAAGCTGACGGACAGGTTCGTCGCCGAAATCGACAAACTCGTCGTGACGAAAGAAGCCGAGATCATGACGGTCTG
A

Upstream 100 bases:

>100_bases
ACTCTCGTTCACATAACGTGGGCTTTGACGCGAGCCCGGGTCGCCGCATCTTGCGCGCGCCGGCCGGCTCGCACCGTTTT
GAAGGTTCGGAGGTTTAAAA

Downstream 100 bases:

>100_bases
GGCCGCTCGCCTCAACACTGTCACGATTTTCACTTCTTTATTTGCAGTCACTGTCCCGACGGCCATGACCTATACCAGCT
CAACCGTGCGCGTGCCTGAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSVADIRKGAEQKMQRSIDAFKNDLSKIRTGRAHTGLLDHIQCDYYGSPVPISQVANLTLIDARTIGVQPWEKKMVPVVE
KAIRESDLGLNPATQGDVIRVPMPALTEERRRELTKVVKSEAETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRAGDD
VQKLTDRFVAEIDKLVVTKEAEIMTV

Sequences:

>Translated_186_residues
MSVADIRKGAEQKMQRSIDAFKNDLSKIRTGRAHTGLLDHIQCDYYGSPVPISQVANLTLIDARTIGVQPWEKKMVPVVE
KAIRESDLGLNPATQGDVIRVPMPALTEERRRELTKVVKSEAETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRAGDD
VQKLTDRFVAEIDKLVVTKEAEIMTV
>Mature_185_residues
SVADIRKGAEQKMQRSIDAFKNDLSKIRTGRAHTGLLDHIQCDYYGSPVPISQVANLTLIDARTIGVQPWEKKMVPVVEK
AIRESDLGLNPATQGDVIRVPMPALTEERRRELTKVVKSEAETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRAGDDV
QKLTDRFVAEIDKLVVTKEAEIMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=31.0344827586207, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI291042689, Length=104, Percent_Identity=39.4230769230769, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=57.1428571428571, Blast_Score=216, Evalue=7e-58,
Organism=Drosophila melanogaster, GI24661488, Length=177, Percent_Identity=30.5084745762712, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20947; Mature: 20816

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVADIRKGAEQKMQRSIDAFKNDLSKIRTGRAHTGLLDHIQCDYYGSPVPISQVANLTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHCCCCE
IDARTIGVQPWEKKMVPVVEKAIRESDLGLNPATQGDVIRVPMPALTEERRRELTKVVKS
EECHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHH
EAETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRAGDDVQKLTDRFVAEIDKLVVTKE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCC
AEIMTV
CCEECC
>Mature Secondary Structure 
SVADIRKGAEQKMQRSIDAFKNDLSKIRTGRAHTGLLDHIQCDYYGSPVPISQVANLTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHCCCCE
IDARTIGVQPWEKKMVPVVEKAIRESDLGLNPATQGDVIRVPMPALTEERRRELTKVVKS
EECHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHH
EAETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRAGDDVQKLTDRFVAEIDKLVVTKE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCC
AEIMTV
CCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA