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The map label for this gene is uppS [H]

Identifier: 91784115

GI number: 91784115

Start: 3042968

End: 3043750

Strand: Reverse

Name: uppS [H]

Synonym: Bxe_A1686

Alternate gene names: 91784115

Gene position: 3043750-3042968 (Counterclockwise)

Preceding gene: 91784116

Following gene: 91784114

Centisome position: 62.17

GC content: 65.64

Gene sequence:

>783_bases
ATGACCTATACCAGCTCAACCGTGCGCGTGCCTGATGTCGCCGCGGTGCCGCGACATATCGCGATCATCATGGACGGCAA
CGGCCGTTGGGCCACCCAGCGGCGCCTGCCGCGCGTGGCGGGCCATACGCGCGGCGTCGACGCGGTGCGTGCGGCCGTCG
AGGCGTGCGCCCGTCAGGGTGTCGAATATCTGACGCTGTTCGCTTTCAGCTCGGAAAACTGGCGCCGTCCCAACGACGAA
GTGTCGTTCCTGATGCGCCTGTTCGTGACCGCGCTGGAGCGCGAGATCGGCAAATTGCACGCGAACGGCATCCGTTTGCG
CGTGGTGGGCGATCTGTCGCGCTTCGACACACGCATCCGCGACCTGATCAGGCGCGCGGAGACCAAGACCGCGCGCAATA
CCCGTCTGACGCTCACGATCGCCGCGAACTACGGCGGCCGCTGGGACATCATGCAGGCCACCCGCAAGCTCGCCGAGCAG
TCGGCGCTGGCGGGCAAGGCGGTCGAAGTGACCGAGGAATCGTTCGCCGAGCACCTCTCAATGGCTTATGCGCCGGAGCC
GGACCTGTTCATCCGCACCGGCGGCGAGCGCCGGGTCAGCAACTTCCTGCTGTGGCAGCTTGCCTACACCGAGTTCTACT
TCACAGACACATTCTGGCCGGATTTCGACGCCGACGCGCTCGGCCACGCCATCGCTTCGTACGCGGAGCGCGAACGCCGC
TTCGGCCGCACCAGTGCTCAACTCGAGCCGCAATCGCAAAACGTCGATTCGCTTCCATGCTAA

Upstream 100 bases:

>100_bases
GTCGTGACGAAAGAAGCCGAGATCATGACGGTCTGAGGCCGCTCGCCTCAACACTGTCACGATTTTCACTTCTTTATTTG
CAGTCACTGTCCCGACGGCC

Downstream 100 bases:

>100_bases
AAACCCGTGTCATCACGGCGATCATCCTGCTGGCGGTATTCCTGCCGGTCACGTTGTTCGCGCCGGTGGGCGCGTTCGGC
GCGCTGATCGCCTTCGTCGT

Product: undecaprenyl pyrophosphate synthetase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MTYTSSTVRVPDVAAVPRHIAIIMDGNGRWATQRRLPRVAGHTRGVDAVRAAVEACARQGVEYLTLFAFSSENWRRPNDE
VSFLMRLFVTALEREIGKLHANGIRLRVVGDLSRFDTRIRDLIRRAETKTARNTRLTLTIAANYGGRWDIMQATRKLAEQ
SALAGKAVEVTEESFAEHLSMAYAPEPDLFIRTGGERRVSNFLLWQLAYTEFYFTDTFWPDFDADALGHAIASYAERERR
FGRTSAQLEPQSQNVDSLPC

Sequences:

>Translated_260_residues
MTYTSSTVRVPDVAAVPRHIAIIMDGNGRWATQRRLPRVAGHTRGVDAVRAAVEACARQGVEYLTLFAFSSENWRRPNDE
VSFLMRLFVTALEREIGKLHANGIRLRVVGDLSRFDTRIRDLIRRAETKTARNTRLTLTIAANYGGRWDIMQATRKLAEQ
SALAGKAVEVTEESFAEHLSMAYAPEPDLFIRTGGERRVSNFLLWQLAYTEFYFTDTFWPDFDADALGHAIASYAERERR
FGRTSAQLEPQSQNVDSLPC
>Mature_259_residues
TYTSSTVRVPDVAAVPRHIAIIMDGNGRWATQRRLPRVAGHTRGVDAVRAAVEACARQGVEYLTLFAFSSENWRRPNDEV
SFLMRLFVTALEREIGKLHANGIRLRVVGDLSRFDTRIRDLIRRAETKTARNTRLTLTIAANYGGRWDIMQATRKLAEQS
ALAGKAVEVTEESFAEHLSMAYAPEPDLFIRTGGERRVSNFLLWQLAYTEFYFTDTFWPDFDADALGHAIASYAERERRF
GRTSAQLEPQSQNVDSLPC

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580742, Length=225, Percent_Identity=33.7777777777778, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI45580738, Length=225, Percent_Identity=33.7777777777778, Blast_Score=132, Evalue=3e-31,
Organism=Escherichia coli, GI1786371, Length=228, Percent_Identity=54.8245614035088, Blast_Score=257, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI71993029, Length=225, Percent_Identity=33.7777777777778, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6323748, Length=233, Percent_Identity=34.7639484978541, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319474, Length=226, Percent_Identity=36.7256637168142, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI18857969, Length=228, Percent_Identity=34.2105263157895, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 29446; Mature: 29314

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS01066 UPP_SYNTHETASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYTSSTVRVPDVAAVPRHIAIIMDGNGRWATQRRLPRVAGHTRGVDAVRAAVEACARQG
CCCCCCCEECCCHHHCCCEEEEEECCCCCCHHHHHCHHHHCCCCCHHHHHHHHHHHHHCC
VEYLTLFAFSSENWRRPNDEVSFLMRLFVTALEREIGKLHANGIRLRVVGDLSRFDTRIR
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHH
DLIRRAETKTARNTRLTLTIAANYGGRWDIMQATRKLAEQSALAGKAVEVTEESFAEHLS
HHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
MAYAPEPDLFIRTGGERRVSNFLLWQLAYTEFYFTDTFWPDFDADALGHAIASYAERERR
HHCCCCCCEEEEECCCHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHH
FGRTSAQLEPQSQNVDSLPC
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TYTSSTVRVPDVAAVPRHIAIIMDGNGRWATQRRLPRVAGHTRGVDAVRAAVEACARQG
CCCCCCEECCCHHHCCCEEEEEECCCCCCHHHHHCHHHHCCCCCHHHHHHHHHHHHHCC
VEYLTLFAFSSENWRRPNDEVSFLMRLFVTALEREIGKLHANGIRLRVVGDLSRFDTRIR
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHH
DLIRRAETKTARNTRLTLTIAANYGGRWDIMQATRKLAEQSALAGKAVEVTEESFAEHLS
HHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
MAYAPEPDLFIRTGGERRVSNFLLWQLAYTEFYFTDTFWPDFDADALGHAIASYAERERR
HHCCCCCCEEEEECCCHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHH
FGRTSAQLEPQSQNVDSLPC
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]