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The map label for this gene is virB11 [H]

Identifier: 91784041

GI number: 91784041

Start: 2964730

End: 2965848

Strand: Reverse

Name: virB11 [H]

Synonym: Bxe_A1762

Alternate gene names: 91784041

Gene position: 2965848-2964730 (Counterclockwise)

Preceding gene: 91784042

Following gene: 91784040

Centisome position: 60.58

GC content: 65.86

Gene sequence:

>1119_bases
ATGACGTTCCGCCCTGATACGTCGGATTCGCCCCACGATCCCATGCTGGCTCGTCTGCCCGACGATGCTTCCGTACGTGA
GCTGATGCGTCCGTTCGCGCCGCTGCTCGAGGACGCCGACGTGACGGAACTCGTGATCAACCGGCCGCAGCGCGTCCTGA
CCGAGAACGCGCGTGGCTGGCACGGTCACGACTGCGTGGACCTCGATTTCGACCGGCTGATGTCATTCGCGGTAGCGGTC
GCCACGCTGACGAACCAGGAGATCTCGGCCCAGCATCCGGTCCTGTCCGCGTTGCTGCCAGGCGACGCGCGCATCCAGAT
TGTGGTGCCGCCGGTCGTGCCGCCGCGCACCGTCTCCATCACGATCCGCCGGCCGTCCGCGCGCGAAAAAAGCCTCGATG
CCTATCGCGACGAAGGTCTGTTCGACGACACGGTATGGCATCGCCCGGACGGGCTCGATGCGGCGCTGCCGGTGCTGCGC
GCAGAGGACCACCGTCTCGTCCGGTGTTTGGAAGAGCACGACTGGGGTGCCTTCTTCGGTCGTGCGGTGACGGACCGGCT
CAATCTCGTGGTCGTCGGCAACACGGGGTCGGGCAAGACCAGTTTCATGAAAACCCTGTGCCGTTCGATTCCGGCGACCG
AGCGGATCGTGACGATCGAGGACGTCCGCGAGCTGTTCATCCGGCACATCGAGAACTGCGTCCACCTGCTGTACAGCAAA
GGCGGGCAGGGCCAGGCGCGCGTCACGCCCGCCGATCTCATCGCCAGCACCATGCGCATGCGTCCCGATCGCGTGTTGCT
CGCCGAGCTGCGCGGTGCCGAAGCCTACGATTTCCTGAAGCTGCTGACGACGGGCCACGCCGGCTCGATCACGAGTTACC
ACGCGCCCAATGCCGCGGTGGCGATCGAGCGTTTCGCGCTGATGGCGAAGGAACACCCCGAGGCTGCTGCCTGGGACGAT
GCCGCGCTCAAGCGCCTGCTGTTCCTGACGATCGACGTTGTCGCGCACATGGAGGCGCAGCCCGTATTCGACGTTGCGGG
CGAGCAGACCGGCAAACGCTGGCGCATGACTGAAGTCTGGTTCGATCCAGTGCGCAAGGCGCGCACCGCGTTCGTCTAG

Upstream 100 bases:

>100_bases
CGCCGACCCTGGCGCAGAACCAGGGCGCAGAATTTACGATCGTCGTTGCACGCGATCTCGATTTCGGATCGGTCTATGCC
CTGAAGCCGGAGGGCACGCA

Downstream 100 bases:

>100_bases
GGGATGGCCATGACCGGACCATCCTCCCGTCTGCTTCAGCATGCCCGACCGGCAGCGGTGACGCTGGTCGTGCTGATATG
CCTTCTTGGCGGACTGGCCG

Product: putative type IV secretion system protein VirB11

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MTFRPDTSDSPHDPMLARLPDDASVRELMRPFAPLLEDADVTELVINRPQRVLTENARGWHGHDCVDLDFDRLMSFAVAV
ATLTNQEISAQHPVLSALLPGDARIQIVVPPVVPPRTVSITIRRPSAREKSLDAYRDEGLFDDTVWHRPDGLDAALPVLR
AEDHRLVRCLEEHDWGAFFGRAVTDRLNLVVVGNTGSGKTSFMKTLCRSIPATERIVTIEDVRELFIRHIENCVHLLYSK
GGQGQARVTPADLIASTMRMRPDRVLLAELRGAEAYDFLKLLTTGHAGSITSYHAPNAAVAIERFALMAKEHPEAAAWDD
AALKRLLFLTIDVVAHMEAQPVFDVAGEQTGKRWRMTEVWFDPVRKARTAFV

Sequences:

>Translated_372_residues
MTFRPDTSDSPHDPMLARLPDDASVRELMRPFAPLLEDADVTELVINRPQRVLTENARGWHGHDCVDLDFDRLMSFAVAV
ATLTNQEISAQHPVLSALLPGDARIQIVVPPVVPPRTVSITIRRPSAREKSLDAYRDEGLFDDTVWHRPDGLDAALPVLR
AEDHRLVRCLEEHDWGAFFGRAVTDRLNLVVVGNTGSGKTSFMKTLCRSIPATERIVTIEDVRELFIRHIENCVHLLYSK
GGQGQARVTPADLIASTMRMRPDRVLLAELRGAEAYDFLKLLTTGHAGSITSYHAPNAAVAIERFALMAKEHPEAAAWDD
AALKRLLFLTIDVVAHMEAQPVFDVAGEQTGKRWRMTEVWFDPVRKARTAFV
>Mature_371_residues
TFRPDTSDSPHDPMLARLPDDASVRELMRPFAPLLEDADVTELVINRPQRVLTENARGWHGHDCVDLDFDRLMSFAVAVA
TLTNQEISAQHPVLSALLPGDARIQIVVPPVVPPRTVSITIRRPSAREKSLDAYRDEGLFDDTVWHRPDGLDAALPVLRA
EDHRLVRCLEEHDWGAFFGRAVTDRLNLVVVGNTGSGKTSFMKTLCRSIPATERIVTIEDVRELFIRHIENCVHLLYSKG
GQGQARVTPADLIASTMRMRPDRVLLAELRGAEAYDFLKLLTTGHAGSITSYHAPNAAVAIERFALMAKEHPEAAAWDDA
ALKRLLFLTIDVVAHMEAQPVFDVAGEQTGKRWRMTEVWFDPVRKARTAFV

Specific function: The type IV secretion system VirB/VirD4 is a major virulence determinant for subversion of human endothelial cell (HEC) function. VirB-dependent changes of HEC include massive cytoskeletal rearrangements, a proinflammatory activation by nuclear factor NF-

COG id: COG0630

COG function: function code NU; Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis

Gene ontology:

Cell location: Cell inner membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014155
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 41575; Mature: 41444

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFRPDTSDSPHDPMLARLPDDASVRELMRPFAPLLEDADVTELVINRPQRVLTENARGW
CCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHCCCCCC
HGHDCVDLDFDRLMSFAVAVATLTNQEISAQHPVLSALLPGDARIQIVVPPVVPPRTVSI
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCCEEEE
TIRRPSAREKSLDAYRDEGLFDDTVWHRPDGLDAALPVLRAEDHRLVRCLEEHDWGAFFG
EEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHH
RAVTDRLNLVVVGNTGSGKTSFMKTLCRSIPATERIVTIEDVRELFIRHIENCVHLLYSK
HHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCC
GGQGQARVTPADLIASTMRMRPDRVLLAELRGAEAYDFLKLLTTGHAGSITSYHAPNAAV
CCCCCEEECHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHH
AIERFALMAKEHPEAAAWDDAALKRLLFLTIDVVAHMEAQPVFDVAGEQTGKRWRMTEVW
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEHHHHH
FDPVRKARTAFV
HHHHHHHHHCCC
>Mature Secondary Structure 
TFRPDTSDSPHDPMLARLPDDASVRELMRPFAPLLEDADVTELVINRPQRVLTENARGW
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHCCCCCC
HGHDCVDLDFDRLMSFAVAVATLTNQEISAQHPVLSALLPGDARIQIVVPPVVPPRTVSI
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCCEEEE
TIRRPSAREKSLDAYRDEGLFDDTVWHRPDGLDAALPVLRAEDHRLVRCLEEHDWGAFFG
EEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHH
RAVTDRLNLVVVGNTGSGKTSFMKTLCRSIPATERIVTIEDVRELFIRHIENCVHLLYSK
HHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCC
GGQGQARVTPADLIASTMRMRPDRVLLAELRGAEAYDFLKLLTTGHAGSITSYHAPNAAV
CCCCCEEECHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHH
AIERFALMAKEHPEAAAWDDAALKRLLFLTIDVVAHMEAQPVFDVAGEQTGKRWRMTEVW
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEHHHHH
FDPVRKARTAFV
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10882236 [H]